EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000269586 (Gene tree)
Gene ID: 102723631
Gene Symbol: CT45A10
Alias: -
Full Name: cancer/testis antigen family 45 member A10
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 12,826 bases
Position: chrX:135,880,752-135,893,577
Accession: 51263
RBP type: canonical RBP
Summary: CT45A10 (Cancer/Testis Antigen Family 45 Member A10) is a Protein Coding gene. An important paralog of this gene is CT45A6.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000481558	INT_SG_DDX_CT_C	PF15300.6	7.5e-27	1	1
ENSP00000484601	INT_SG_DDX_CT_C	PF15300.6	7.5e-27	1	1

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000617981	CT45A10-202	578	XM_011531239	ENSP00000481558	189 (aa)	XP_011529541	P0DMU9
ENST00000611668	CT45A10-201	1010	XM_011531238	ENSP00000484601	189 (aa)	XP_011529540	P0DMU9

Gene Model

Click here to download ENSG00000269586's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000269586's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000269586	CT45A10	69	38.235	ENSAMEG00000005934	-	80	38.235	Ailuropoda_melanoleuca
ENSG00000269586	CT45A10	98	70.430	ENSANAG00000006559	-	98	70.430	Aotus_nancymaae
ENSG00000269586	CT45A10	99	68.617	ENSCJAG00000004135	-	99	68.617	Callithrix_jacchus
ENSG00000269586	CT45A10	92	33.143	ENSCAFG00000014436	-	90	33.143	Canis_familiaris
ENSG00000269586	CT45A10	87	40.698	ENSCAFG00020000069	-	61	40.698	Canis_lupus_dingo
ENSG00000269586	CT45A10	85	45.882	ENSCAFG00020024726	-	76	45.882	Canis_lupus_dingo
ENSG00000269586	CT45A10	100	51.295	ENSTSYG00000003411	-	99	51.295	Carlito_syrichta
ENSG00000269586	CT45A10	100	80.952	ENSCATG00000026275	-	89	80.952	Cercocebus_atys
ENSG00000269586	CT45A10	100	81.481	ENSCSAG00000007640	-	93	81.481	Chlorocebus_sabaeus
ENSG00000269586	CT45A10	100	68.783	ENSCSAG00000015072	-	100	68.783	Chlorocebus_sabaeus
ENSG00000269586	CT45A10	100	79.894	ENSCANG00000040837	-	99	79.894	Colobus_angolensis_palliatus
ENSG00000269586	CT45A10	68	37.209	ENSCGRG00001016867	Gm648	60	37.209	Cricetulus_griseus_chok1gshd
ENSG00000269586	CT45A10	68	37.209	ENSCGRG00000002325	Gm648	58	37.209	Cricetulus_griseus_crigri
ENSG00000269586	CT45A10	96	80.663	ENSMFAG00000036609	-	100	80.663	Macaca_fascicularis
ENSG00000269586	CT45A10	100	80.952	ENSMFAG00000035558	-	93	80.952	Macaca_fascicularis
ENSG00000269586	CT45A10	100	51.852	ENSMMUG00000042170	-	100	51.852	Macaca_mulatta
ENSG00000269586	CT45A10	100	80.423	ENSMMUG00000021984	-	91	80.423	Macaca_mulatta
ENSG00000269586	CT45A10	100	81.481	ENSMNEG00000028699	-	93	81.481	Macaca_nemestrina
ENSG00000269586	CT45A10	96	80.663	ENSMNEG00000040510	-	100	80.663	Macaca_nemestrina
ENSG00000269586	CT45A10	79	68.667	ENSMLEG00000042160	-	77	68.667	Mandrillus_leucophaeus
ENSG00000269586	CT45A10	100	80.952	ENSMLEG00000000289	-	93	80.952	Mandrillus_leucophaeus
ENSG00000269586	CT45A10	75	35.811	MGP_CAROLIEiJ_G0033087	Gm648	64	37.324	Mus_caroli
ENSG00000269586	CT45A10	99	33.466	MGP_CAROLIEiJ_G0033085	Ints6l	77	49.153	Mus_caroli
ENSG00000269586	CT45A10	76	36.424	ENSMUSG00000064016	Gm648	68	36.424	Mus_musculus
ENSG00000269586	CT45A10	99	34.400	ENSMUSG00000035967	Ints6l	76	50.847	Mus_musculus
ENSG00000269586	CT45A10	99	33.466	MGP_PahariEiJ_G0031627	Ints6l	77	50.847	Mus_pahari
ENSG00000269586	CT45A10	76	36.424	MGP_SPRETEiJ_G0034242	Gm648	68	36.424	Mus_spretus
ENSG00000269586	CT45A10	99	35.200	MGP_SPRETEiJ_G0034240	Ints6l	77	50.847	Mus_spretus
ENSG00000269586	CT45A10	99	35.233	ENSMPUG00000012647	-	100	35.233	Mustela_putorius_furo
ENSG00000269586	CT45A10	100	86.772	ENSNLEG00000002303	-	100	86.772	Nomascus_leucogenys
ENSG00000269586	CT45A10	100	44.041	ENSOCUG00000027335	-	93	44.041	Oryctolagus_cuniculus
ENSG00000269586	CT45A10	99	39.153	ENSOARG00000011598	-	91	39.153	Ovis_aries
ENSG00000269586	CT45A10	100	94.709	ENSPTRG00000047355	-	100	94.709	Pan_troglodytes
ENSG00000269586	CT45A10	100	71.958	ENSPTRG00000028196	-	100	71.958	Pan_troglodytes
ENSG00000269586	CT45A10	100	95.767	ENSPTRG00000047577	CT45A10	100	95.767	Pan_troglodytes
ENSG00000269586	CT45A10	100	80.952	ENSPANG00000023647	-	99	80.952	Papio_anubis
ENSG00000269586	CT45A10	100	80.952	ENSPANG00000014397	-	89	80.952	Papio_anubis
ENSG00000269586	CT45A10	90	86.550	ENSPPYG00000020753	-	99	86.550	Pongo_abelii
ENSG00000269586	CT45A10	100	76.842	ENSPPYG00000020754	-	99	76.842	Pongo_abelii
ENSG00000269586	CT45A10	100	92.593	ENSPPYG00000020755	-	100	92.593	Pongo_abelii
ENSG00000269586	CT45A10	69	46.154	ENSPVAG00000002652	-	96	46.154	Pteropus_vampyrus
ENSG00000269586	CT45A10	99	82.979	ENSRBIG00000006469	-	99	82.979	Rhinopithecus_bieti
ENSG00000269586	CT45A10	100	81.481	ENSRROG00000017978	-	93	81.481	Rhinopithecus_roxellana
ENSG00000269586	CT45A10	99	68.085	ENSSBOG00000024560	-	99	68.085	Saimiri_boliviensis_boliviensis
ENSG00000269586	CT45A10	89	38.674	ENSUAMG00000021456	-	83	38.674	Ursus_americanus
ENSG00000269586	CT45A10	96	39.583	ENSUAMG00000005870	-	99	39.583	Ursus_americanus
ENSG00000269586	CT45A10	99	39.899	ENSUAMG00000003018	-	93	39.899	Ursus_americanus
ENSG00000269586	CT45A10	54	49.515	ENSVPAG00000011549	-	60	48.276	Vicugna_pacos
ENSG00000269586	CT45A10	99	33.158	ENSVVUG00000010778	-	91	33.158	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0032039	integrator complex	21873635.	IBA	Component
GO:0034472	snRNA 3'-end processing	21873635.	IBA	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
CESC	chrX	135883032	Missense_Mutation	novel	K132E	0.1	INT_SG_DDX_CT_C
COAD	chrX	135883067	Missense_Mutation	NA	Q120R	0.06
COAD	chrX	135883010	Missense_Mutation	NA	R139Q	0.12	INT_SG_DDX_CT_C
HNSC	chrX	135883018	Nonsense_Mutation	NA	C136*	0.2	INT_SG_DDX_CT_C
HNSC	chrX	135883037	Missense_Mutation	novel	V130E	0.2	INT_SG_DDX_CT_C
KIRC	chrX	135883084	Nonsense_Mutation	novel	S114_S115ins*	0.03
LIHC	chrX	135883079	Missense_Mutation	NA	P116R	0.4
LUAD	chrX	135883018	Nonsense_Mutation	NA	C136*	0.3	INT_SG_DDX_CT_C
LUAD	chrX	135883085	Missense_Mutation	NA	S114Y	0.07
LUAD	chrX	135883029	Nonsense_Mutation	NA	E133*	0.12	INT_SG_DDX_CT_C
LUSC	chrX	135883068	Missense_Mutation	novel	Q120K	0.15
PRAD	chrX	135883126	Missense_Mutation	NA	S100R	0.59
READ	chrX	135883127	Missense_Mutation	NA	S100I	0.79
SKCM	chrX	135883079	Missense_Mutation	novel	P116L	0.36
SKCM	chrX	135883010	Missense_Mutation	NA	R139Q	0.58	INT_SG_DDX_CT_C
SKCM	chrX	135883082	Missense_Mutation	novel	S115F	0.66
SKCM	chrX	135883029	Missense_Mutation	NA	E133K	0.74	INT_SG_DDX_CT_C
SKCM	chrX	135883031	Missense_Mutation	novel	K132R	0.75	INT_SG_DDX_CT_C
SKCM	chrX	135883010	Missense_Mutation	NA	R139Q	0.77	INT_SG_DDX_CT_C
UCEC	chrX	135883042	Silent	novel	C128C	0.1
UCEC	chrX	135883019	Missense_Mutation	novel	C136Y	0.41	INT_SG_DDX_CT_C
UCEC	chrX	135883022	Missense_Mutation	novel	R135Q	0.36	INT_SG_DDX_CT_C
UCEC	chrX	135883055	Missense_Mutation	novel	A124V	0.11	INT_SG_DDX_CT_C
UCEC	chrX	135883113	Missense_Mutation	novel	D105Y	0.04

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value

Survival Analysis

Cancer	P-value	Q-value
LGG	0.0027	Kaplan-Meier Survival Analysis
OV	0.002	Kaplan-Meier Survival Analysis