EuRBPDB

Description

Ensembl ID: ENSG00000270011 (Gene tree)
Gene ID: 100529215
Gene Symbol: ZNF559-ZNF177
Alias: -
Full Name: ZNF559-ZNF177 readthrough
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 58,444 bases
Position: chr19:9,324,174-9,382,617
Accession: 42964
RBP type: canonical RBP
Summary: This locus represents naturally occurring read-through transcription between the neighboring zinc finger protein 559 (ZNF559) and zinc finger protein 177 (ZNF177) genes on chromosome 19. Alternative splicing results in multiple transcript variants, which encode the ZNF177 protein due to either leaky scanning by ribosomes, or absence of the ZNF559 start codon. [provided by RefSeq, Jan 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000445323	zf-C2H2	PF00096.26	3.7e-46	1	7
ENSP00000445323	zf-C2H2	PF00096.26	3.7e-46	2	7
ENSP00000445323	zf-C2H2	PF00096.26	3.7e-46	3	7
ENSP00000445323	zf-C2H2	PF00096.26	3.7e-46	4	7
ENSP00000445323	zf-C2H2	PF00096.26	3.7e-46	5	7
ENSP00000445323	zf-C2H2	PF00096.26	3.7e-46	6	7
ENSP00000445323	zf-C2H2	PF00096.26	3.7e-46	7	7
ENSP00000445323	zf-met	PF12874.7	0.0015	1	2
ENSP00000445323	zf-met	PF12874.7	0.0015	2	2

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000603974	ZNF559-ZNF177-207	911	-	ENSP00000473911	111 (aa)	-	S4R342
ENST00000605522	ZNF559-ZNF177-215	549	-	-	- (aa)	-	-
ENST00000605071	ZNF559-ZNF177-211	725	-	ENSP00000474076	84 (aa)	-	S4R3A1
ENST00000603099	ZNF559-ZNF177-205	584	-	-	- (aa)	-	-
ENST00000605301	ZNF559-ZNF177-213	565	-	-	- (aa)	-	-
ENST00000593242	ZNF559-ZNF177-203	586	-	ENSP00000474108	67 (aa)	-	S4R3B1
ENST00000603024	ZNF559-ZNF177-204	610	-	ENSP00000474980	76 (aa)	-	S4R422
ENST00000446085	ZNF559-ZNF177-201	2470	-	ENSP00000413568	120 (aa)	-	UPI0001F6F9E9
ENST00000605093	ZNF559-ZNF177-212	591	-	ENSP00000474918	46 (aa)	-	S4R401
ENST00000604543	ZNF559-ZNF177-208	585	-	ENSP00000474716	66 (aa)	-	S4R3T9
ENST00000605471	ZNF559-ZNF177-214	634	-	-	- (aa)	-	-
ENST00000605006	ZNF559-ZNF177-210	597	-	ENSP00000473974	47 (aa)	-	S4R367
ENST00000603656	ZNF559-ZNF177-206	827	-	ENSP00000474602	126 (aa)	-	S4R3Q2
ENST00000605775	ZNF559-ZNF177-216	604	-	ENSP00000474354	53 (aa)	-	S4R3H7
ENST00000604886	ZNF559-ZNF177-209	587	-	ENSP00000473968	82 (aa)	-	S4R365
ENST00000541595	ZNF559-ZNF177-202	2435	-	ENSP00000445323	321 (aa)	-	UPI000013C64B

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa05168	Herpes simplex virus 1 infection	KEGG

Protein-Protein Interaction (PPI)

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000270011	ZNF559-ZNF177	99	96.172	ENSANAG00000012491	-	100	96.172	Aotus_nancymaae
ENSG00000270011	ZNF559-ZNF177	100	85.535	ENSFCAG00000040603	-	99	85.535	Felis_catus
ENSG00000270011	ZNF559-ZNF177	99	93.659	ENSHGLG00100011420	-	100	93.659	Heterocephalus_glaber_male
ENSG00000270011	ZNF559-ZNF177	100	98.754	ENSPPAG00000034550	-	100	98.754	Pan_paniscus
ENSG00000270011	ZNF559-ZNF177	100	85.535	ENSPPRG00000000109	-	99	85.535	Panthera_pardus
ENSG00000270011	ZNF559-ZNF177	100	85.535	ENSPTIG00000016395	-	99	85.535	Panthera_tigris_altaica
ENSG00000270011	ZNF559-ZNF177	93	97.297	ENSPTRG00000010445	-	100	100.000	Pan_troglodytes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	8661005.	TAS	Process
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0046872	metal ion binding	-	IEA	Function
GO:0072562	blood microparticle	22516433.	HDA	Component