EuRBPDB

Description

RBDs

Literatures

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000275111 (Gene tree)
Gene ID: 7549
Gene Symbol: ZNF2
Alias: A1-5|ZNF661|Zfp661
Full Name: zinc finger protein 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 18,901 bases
Position: chr2:95,165,417-95,184,317
Accession: 12991
RBP type: canonical RBP
Summary: The protein encoded by this gene belongs to the C2H2-type zinc-finger protein family. The exact function of this gene is not known, however, zinc-finger proteins are known to interact with DNA and function as transcription regulators. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000477960	zf-C2H2	PF00096.26	1.2e-51	1	9
ENSP00000477960	zf-C2H2	PF00096.26	1.2e-51	2	9
ENSP00000477960	zf-C2H2	PF00096.26	1.2e-51	3	9
ENSP00000477960	zf-C2H2	PF00096.26	1.2e-51	4	9
ENSP00000477960	zf-C2H2	PF00096.26	1.2e-51	5	9
ENSP00000477960	zf-C2H2	PF00096.26	1.2e-51	6	9
ENSP00000477960	zf-C2H2	PF00096.26	1.2e-51	7	9
ENSP00000477960	zf-C2H2	PF00096.26	1.2e-51	8	9
ENSP00000477960	zf-C2H2	PF00096.26	1.2e-51	9	9
ENSP00000480057	zf-C2H2	PF00096.26	3.9e-51	1	9
ENSP00000480057	zf-C2H2	PF00096.26	3.9e-51	2	9
ENSP00000480057	zf-C2H2	PF00096.26	3.9e-51	3	9
ENSP00000480057	zf-C2H2	PF00096.26	3.9e-51	4	9
ENSP00000480057	zf-C2H2	PF00096.26	3.9e-51	5	9
ENSP00000480057	zf-C2H2	PF00096.26	3.9e-51	6	9
ENSP00000480057	zf-C2H2	PF00096.26	3.9e-51	7	9
ENSP00000480057	zf-C2H2	PF00096.26	3.9e-51	8	9
ENSP00000480057	zf-C2H2	PF00096.26	3.9e-51	9	9
ENSP00000483131	zf-C2H2	PF00096.26	4.1e-51	1	9
ENSP00000483131	zf-C2H2	PF00096.26	4.1e-51	2	9
ENSP00000483131	zf-C2H2	PF00096.26	4.1e-51	3	9
ENSP00000483131	zf-C2H2	PF00096.26	4.1e-51	4	9
ENSP00000483131	zf-C2H2	PF00096.26	4.1e-51	5	9
ENSP00000483131	zf-C2H2	PF00096.26	4.1e-51	6	9
ENSP00000483131	zf-C2H2	PF00096.26	4.1e-51	7	9
ENSP00000483131	zf-C2H2	PF00096.26	4.1e-51	8	9
ENSP00000483131	zf-C2H2	PF00096.26	4.1e-51	9	9
ENSP00000480297	zf-C2H2	PF00096.26	1.2e-50	1	9
ENSP00000480297	zf-C2H2	PF00096.26	1.2e-50	2	9
ENSP00000480297	zf-C2H2	PF00096.26	1.2e-50	3	9
ENSP00000480297	zf-C2H2	PF00096.26	1.2e-50	4	9
ENSP00000480297	zf-C2H2	PF00096.26	1.2e-50	5	9
ENSP00000480297	zf-C2H2	PF00096.26	1.2e-50	6	9
ENSP00000480297	zf-C2H2	PF00096.26	1.2e-50	7	9
ENSP00000480297	zf-C2H2	PF00096.26	1.2e-50	8	9
ENSP00000480297	zf-C2H2	PF00096.26	1.2e-50	9	9
ENSP00000482030	zf-C2H2	PF00096.26	1.6e-50	1	9
ENSP00000482030	zf-C2H2	PF00096.26	1.6e-50	2	9
ENSP00000482030	zf-C2H2	PF00096.26	1.6e-50	3	9
ENSP00000482030	zf-C2H2	PF00096.26	1.6e-50	4	9
ENSP00000482030	zf-C2H2	PF00096.26	1.6e-50	5	9
ENSP00000482030	zf-C2H2	PF00096.26	1.6e-50	6	9
ENSP00000482030	zf-C2H2	PF00096.26	1.6e-50	7	9
ENSP00000482030	zf-C2H2	PF00096.26	1.6e-50	8	9
ENSP00000482030	zf-C2H2	PF00096.26	1.6e-50	9	9
ENSP00000477960	zf-met	PF12874.7	1.1e-06	1	1
ENSP00000483131	zf-met	PF12874.7	4.6e-06	1	1
ENSP00000480057	zf-met	PF12874.7	4.7e-06	1	1
ENSP00000480297	zf-met	PF12874.7	1.1e-05	1	1
ENSP00000482030	zf-met	PF12874.7	1.5e-05	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
29511296	Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.	Sci Rep	2018 Mar 6	Iradi MCG	doi: 10.1038/s41598-018-21371-4.

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000617923	ZNF2-204	3885	-	ENSP00000480057	383 (aa)	-	B0AZN8
ENST00000611147	ZNF2-201	1465	-	ENSP00000482030	438 (aa)	-	A0A087WYR5
ENST00000614034	ZNF2-203	2601	-	ENSP00000480297	425 (aa)	-	Q9BSG1
ENST00000611463	ZNF2-202	3737	-	ENSP00000477960	345 (aa)	-	Q68CY6
ENST00000622059	ZNF2-205	1624	-	ENSP00000483131	387 (aa)	-	A0A087X063

Gene Model

Click here to download ENSG00000275111's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05168	Herpes simplex virus 1 infection	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000275111's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000275111	ZNF2	100	93.023	ENSANAG00000031410	ZNF2	100	93.023	Aotus_nancymaae
ENSG00000275111	ZNF2	100	93.023	ENSCJAG00000018930	ZNF2	100	93.023	Callithrix_jacchus
ENSG00000275111	ZNF2	100	83.803	ENSCHIG00000012483	ZNF2	100	83.803	Capra_hircus
ENSG00000275111	ZNF2	100	85.838	ENSTSYG00000004899	ZNF2	100	85.309	Carlito_syrichta
ENSG00000275111	ZNF2	100	83.815	ENSCAPG00000017499	ZNF2	100	83.862	Cavia_aperea
ENSG00000275111	ZNF2	100	82.292	ENSCPOG00000035126	ZNF2	100	81.690	Cavia_porcellus
ENSG00000275111	ZNF2	100	92.506	ENSCCAG00000027604	ZNF2	100	92.506	Cebus_capucinus
ENSG00000275111	ZNF2	100	95.607	ENSCATG00000035067	ZNF2	100	95.607	Cercocebus_atys
ENSG00000275111	ZNF2	100	83.812	ENSCLAG00000003116	ZNF2	100	83.294	Chinchilla_lanigera
ENSG00000275111	ZNF2	100	94.778	ENSCSAG00000017407	ZNF2	100	94.778	Chlorocebus_sabaeus
ENSG00000275111	ZNF2	100	94.057	ENSCANG00000036216	ZNF2	100	94.057	Colobus_angolensis_palliatus
ENSG00000275111	ZNF2	100	84.638	ENSDORG00000016625	Zfp661	99	85.196	Dipodomys_ordii
ENSG00000275111	ZNF2	100	87.283	ENSEASG00005005268	ZNF2	100	87.397	Equus_asinus_asinus
ENSG00000275111	ZNF2	98	86.095	ENSECAG00000016130	ZNF2	88	84.987	Equus_caballus
ENSG00000275111	ZNF2	100	82.552	ENSFDAG00000008549	ZNF2	99	81.455	Fukomys_damarensis
ENSG00000275111	ZNF2	100	97.971	ENSGGOG00000039661	ZNF2	100	97.971	Gorilla_gorilla
ENSG00000275111	ZNF2	100	82.552	ENSHGLG00000005282	ZNF2	100	81.455	Heterocephalus_glaber_female
ENSG00000275111	ZNF2	100	82.552	ENSHGLG00100018809	ZNF2	100	81.455	Heterocephalus_glaber_male
ENSG00000275111	ZNF2	100	81.201	ENSSTOG00000026739	ZNF2	100	80.235	Ictidomys_tridecemlineatus
ENSG00000275111	ZNF2	100	81.510	ENSJJAG00000014531	Zfp661	100	80.986	Jaculus_jaculus
ENSG00000275111	ZNF2	100	83.099	ENSLAFG00000006959	ZNF2	100	83.099	Loxodonta_africana
ENSG00000275111	ZNF2	100	95.349	ENSMFAG00000039940	ZNF2	100	95.349	Macaca_fascicularis
ENSG00000275111	ZNF2	100	95.349	ENSMMUG00000019423	ZNF2	100	95.349	Macaca_mulatta
ENSG00000275111	ZNF2	100	95.090	ENSMNEG00000035673	ZNF2	100	95.090	Macaca_nemestrina
ENSG00000275111	ZNF2	100	95.607	ENSMLEG00000042823	ZNF2	100	95.607	Mandrillus_leucophaeus
ENSG00000275111	ZNF2	100	82.262	ENSMICG00000031069	ZNF2	100	82.262	Microcebus_murinus
ENSG00000275111	ZNF2	99	65.468	ENSMODG00000023146	-	99	65.468	Monodelphis_domestica
ENSG00000275111	ZNF2	100	79.373	MGP_CAROLIEiJ_G0024261	Zfp661	99	79.294	Mus_caroli
ENSG00000275111	ZNF2	100	79.634	ENSMUSG00000034800	Zfp661	99	79.529	Mus_musculus
ENSG00000275111	ZNF2	100	78.851	MGP_PahariEiJ_G0025706	Zfp661	99	78.824	Mus_pahari
ENSG00000275111	ZNF2	100	79.634	MGP_SPRETEiJ_G0025181	Zfp661	99	79.294	Mus_spretus
ENSG00000275111	ZNF2	100	83.854	ENSNGAG00000014357	Zfp661	98	82.629	Nannospalax_galili
ENSG00000275111	ZNF2	100	97.391	ENSNLEG00000000004	ZNF2	100	97.391	Nomascus_leucogenys
ENSG00000275111	ZNF2	97	55.988	ENSMEUG00000004196	-	99	55.405	Notamacropus_eugenii
ENSG00000275111	ZNF2	97	67.262	ENSMEUG00000005903	-	86	65.946	Notamacropus_eugenii
ENSG00000275111	ZNF2	100	84.635	ENSOPRG00000001825	ZNF2	100	84.038	Ochotona_princeps
ENSG00000275111	ZNF2	100	79.896	ENSODEG00000005837	ZNF2	100	79.059	Octodon_degus
ENSG00000275111	ZNF2	99	81.579	ENSOCUG00000003561	ZNF2	97	82.527	Oryctolagus_cuniculus
ENSG00000275111	ZNF2	100	84.115	ENSOARG00000014166	ZNF2	89	84.038	Ovis_aries
ENSG00000275111	ZNF2	100	99.294	ENSPPAG00000042229	ZNF2	100	99.294	Pan_paniscus
ENSG00000275111	ZNF2	100	99.529	ENSPTRG00000012207	ZNF2	100	99.529	Pan_troglodytes
ENSG00000275111	ZNF2	100	95.607	ENSPANG00000018071	ZNF2	100	95.607	Papio_anubis
ENSG00000275111	ZNF2	91	68.639	ENSPCIG00000023001	-	100	44.476	Phascolarctos_cinereus
ENSG00000275111	ZNF2	99	65.000	ENSPCIG00000023002	-	99	65.250	Phascolarctos_cinereus
ENSG00000275111	ZNF2	100	97.650	ENSPPYG00000012053	ZNF2	100	97.412	Pongo_abelii
ENSG00000275111	ZNF2	100	75.117	ENSPCAG00000016939	ZNF2	100	75.117	Procavia_capensis
ENSG00000275111	ZNF2	100	84.833	ENSPCOG00000021930	ZNF2	100	84.833	Propithecus_coquereli
ENSG00000275111	ZNF2	98	83.728	ENSPVAG00000006095	ZNF2	100	80.516	Pteropus_vampyrus
ENSG00000275111	ZNF2	98	81.899	ENSRNOG00000015188	AABR07053681.1	100	81.534	Rattus_norvegicus
ENSG00000275111	ZNF2	100	93.023	ENSSBOG00000030730	ZNF2	100	93.023	Saimiri_boliviensis_boliviensis
ENSG00000275111	ZNF2	99	53.023	ENSSHAG00000011714	-	100	53.488	Sarcophilus_harrisii
ENSG00000275111	ZNF2	99	64.844	ENSSHAG00000011906	-	100	64.789	Sarcophilus_harrisii
ENSG00000275111	ZNF2	100	65.421	ENSSARG00000002081	ZNF2	100	65.421	Sorex_araneus
ENSG00000275111	ZNF2	100	82.812	ENSSSCG00000008117	ZNF2	100	82.812	Sus_scrofa
ENSG00000275111	ZNF2	100	74.178	ENSTBEG00000012847	ZNF2	100	74.178	Tupaia_belangeri
ENSG00000275111	ZNF2	99	84.514	ENSTTRG00000004968	ZNF2	99	84.397	Tursiops_truncatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0006355	regulation of transcription, DNA-templated	1945843.	NAS	Process
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0008270	zinc ion binding	1945843.	NAS	Function