EuRBPDB

Description

RBDs

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Description

Ensembl ID: ENSHCOG00000018918 (Gene tree)
Gene ID: 109510803
Gene Symbol: srsf1a
Alias: sfrs1a|sfrs1l|wu:fb52g10|wu:fb97g12|zgc:66146
Full Name: serine and arginine rich splicing factor 1
Gene Type: protein_coding
Species: Hippocampus_comes
Status: putative
Strand: Plus strand
Length: 3658 bases
Position: chrKV880533.1:689311-692968
Accession: 109510803
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSHCOP00000015332	RRM_1	PF00076.22	2.6e-31	1	2
ENSHCOP00000015332	RRM_1	PF00076.22	2.6e-31	2	2

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSHCOT00000023226	-	1147	XM_019861395	ENSHCOP00000015332	256 (aa)	XP_019716954	UPI00094E285A

Gene Model

Click here to download ENSHCOG00000018918's gene model file

Pathways

Pathway ID	Pathway Name	Source
hcq03040	Spliceosome	KEGG
hcq05168	Herpes simplex virus 1 infection	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSHCOG00000018918's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSHCOG00000018918	srsf1a	66	43.529	ENSHCOG00000002740	srsf6a	51	44.578
ENSHCOG00000018918	srsf1a	77	79.397	ENSHCOG00000008016	-	77	77.889
ENSHCOG00000018918	srsf1a	66	42.135	ENSHCOG00000017557	srsf5a	85	33.460
ENSHCOG00000018918	srsf1a	71	49.189	ENSHCOG00000017311	srsf9	76	47.340
ENSHCOG00000018918	srsf1a	64	46.857	ENSHCOG00000005592	srsf5b	58	44.318
ENSHCOG00000018918	srsf1a	66	45.614	ENSHCOG00000012540	srsf4	62	44.253

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSHCOG00000018918	srsf1a	97	81.928	ENSG00000136450	SRSF1	95	90.323	Homo_sapiens
ENSHCOG00000018918	srsf1a	78	91.457	ENSAPOG00000002748	-	79	88.945	Acanthochromis_polyacanthus
ENSHCOG00000018918	srsf1a	77	87.940	ENSAPOG00000008542	-	80	87.940	Acanthochromis_polyacanthus
ENSHCOG00000018918	srsf1a	77	84.264	ENSAMEG00000002635	SRSF1	77	85.279	Ailuropoda_melanoleuca
ENSHCOG00000018918	srsf1a	88	86.161	ENSACIG00000008091	srsf1a	83	89.950	Amphilophus_citrinellus
ENSHCOG00000018918	srsf1a	88	86.607	ENSAOCG00000010671	-	84	90.452	Amphiprion_ocellaris
ENSHCOG00000018918	srsf1a	77	87.940	ENSAOCG00000000337	-	80	87.940	Amphiprion_ocellaris
ENSHCOG00000018918	srsf1a	88	86.607	ENSAPEG00000009915	-	84	90.452	Amphiprion_percula
ENSHCOG00000018918	srsf1a	77	87.940	ENSAPEG00000023352	-	79	87.940	Amphiprion_percula
ENSHCOG00000018918	srsf1a	78	91.960	ENSATEG00000022403	-	78	90.452	Anabas_testudineus
ENSHCOG00000018918	srsf1a	80	81.863	ENSATEG00000021567	-	80	81.818	Anabas_testudineus
ENSHCOG00000018918	srsf1a	77	86.802	ENSACAG00000005542	-	78	86.294	Anolis_carolinensis
ENSHCOG00000018918	srsf1a	97	81.928	ENSANAG00000020583	-	95	88.406	Aotus_nancymaae
ENSHCOG00000018918	srsf1a	78	65.500	ENSANAG00000025417	-	73	65.482	Aotus_nancymaae
ENSHCOG00000018918	srsf1a	78	86.070	ENSAMXG00000035996	srsf1a	80	87.065	Astyanax_mexicanus
ENSHCOG00000018918	srsf1a	54	76.129	ENSAMXG00000024373	-	72	78.065	Astyanax_mexicanus
ENSHCOG00000018918	srsf1a	97	81.928	ENSBTAG00000014766	SRSF1	78	87.310	Bos_taurus
ENSHCOG00000018918	srsf1a	77	80.711	ENSCJAG00000008111	-	86	77.665	Callithrix_jacchus
ENSHCOG00000018918	srsf1a	97	81.928	ENSCJAG00000041713	-	95	88.406	Callithrix_jacchus
ENSHCOG00000018918	srsf1a	97	81.928	ENSCAFG00000017430	SRSF1	76	87.310	Canis_familiaris
ENSHCOG00000018918	srsf1a	97	81.928	ENSCAFG00020025632	-	76	87.310	Canis_lupus_dingo
ENSHCOG00000018918	srsf1a	77	87.817	ENSCHIG00000010787	SRSF1	78	87.310	Capra_hircus
ENSHCOG00000018918	srsf1a	97	81.928	ENSTSYG00000013899	-	95	88.406	Carlito_syrichta
ENSHCOG00000018918	srsf1a	97	81.928	ENSCPOG00000032681	-	78	87.310	Cavia_porcellus
ENSHCOG00000018918	srsf1a	97	81.928	ENSCCAG00000029484	-	95	88.406	Cebus_capucinus
ENSHCOG00000018918	srsf1a	97	81.928	ENSCATG00000042294	-	95	88.406	Cercocebus_atys
ENSHCOG00000018918	srsf1a	97	81.928	ENSCLAG00000014707	-	78	87.310	Chinchilla_lanigera
ENSHCOG00000018918	srsf1a	98	80.800	ENSCSAG00000005642	-	76	86.294	Chlorocebus_sabaeus
ENSHCOG00000018918	srsf1a	77	87.817	ENSCHOG00000001899	SRSF1	78	87.310	Choloepus_hoffmanni
ENSHCOG00000018918	srsf1a	97	81.526	ENSCPBG00000009851	-	78	86.802	Chrysemys_picta_bellii
ENSHCOG00000018918	srsf1a	97	81.928	ENSCANG00000029726	-	95	88.406	Colobus_angolensis_palliatus
ENSHCOG00000018918	srsf1a	97	81.928	ENSCGRG00001000670	Srsf1	76	87.310	Cricetulus_griseus_chok1gshd
ENSHCOG00000018918	srsf1a	97	81.928	ENSCGRG00000005590	Srsf1	78	87.310	Cricetulus_griseus_crigri
ENSHCOG00000018918	srsf1a	78	93.467	ENSCSEG00000014272	-	79	90.955	Cynoglossus_semilaevis
ENSHCOG00000018918	srsf1a	77	81.731	ENSCSEG00000009973	-	79	80.769	Cynoglossus_semilaevis
ENSHCOG00000018918	srsf1a	78	84.925	ENSCVAG00000005458	-	92	83.422	Cyprinodon_variegatus
ENSHCOG00000018918	srsf1a	78	91.960	ENSCVAG00000018617	-	79	90.452	Cyprinodon_variegatus
ENSHCOG00000018918	srsf1a	78	85.500	ENSDARG00000017843	srsf1b	80	84.500	Danio_rerio
ENSHCOG00000018918	srsf1a	78	84.951	ENSDARG00000057691	srsf1a	100	83.420	Danio_rerio
ENSHCOG00000018918	srsf1a	97	81.928	ENSDNOG00000011737	-	76	87.310	Dasypus_novemcinctus
ENSHCOG00000018918	srsf1a	97	81.928	ENSDORG00000015082	Srsf1	78	87.310	Dipodomys_ordii
ENSHCOG00000018918	srsf1a	72	84.783	ENSETEG00000005349	-	62	87.500	Echinops_telfairi
ENSHCOG00000018918	srsf1a	97	81.928	ENSEASG00005002922	-	76	87.310	Equus_asinus_asinus
ENSHCOG00000018918	srsf1a	77	87.817	ENSECAG00000016654	SRSF1	78	87.310	Equus_caballus
ENSHCOG00000018918	srsf1a	72	85.870	ENSEEUG00000009255	-	62	88.587	Erinaceus_europaeus
ENSHCOG00000018918	srsf1a	78	89.000	ENSELUG00000021646	srsf1a	78	86.000	Esox_lucius
ENSHCOG00000018918	srsf1a	97	81.928	ENSFCAG00000002250	-	90	88.108	Felis_catus
ENSHCOG00000018918	srsf1a	75	92.453	ENSFALG00000005062	-	76	71.574	Ficedula_albicollis
ENSHCOG00000018918	srsf1a	97	81.928	ENSFDAG00000010646	-	78	87.310	Fukomys_damarensis
ENSHCOG00000018918	srsf1a	88	86.607	ENSFHEG00000003174	srsf1a	84	90.452	Fundulus_heteroclitus
ENSHCOG00000018918	srsf1a	79	85.644	ENSGMOG00000014787	-	80	82.234	Gadus_morhua
ENSHCOG00000018918	srsf1a	77	88.325	ENSGALG00000005525	SRSF1	78	86.802	Gallus_gallus
ENSHCOG00000018918	srsf1a	77	82.741	ENSGACG00000020621	srsf1b	78	80.203	Gasterosteus_aculeatus
ENSHCOG00000018918	srsf1a	97	81.526	ENSGAGG00000022965	-	76	86.802	Gopherus_agassizii
ENSHCOG00000018918	srsf1a	97	81.928	ENSGGOG00000004386	SRSF1	95	88.406	Gorilla_gorilla
ENSHCOG00000018918	srsf1a	88	86.161	ENSHBUG00000016788	srsf1a	81	89.950	Haplochromis_burtoni
ENSHCOG00000018918	srsf1a	66	86.905	ENSHGLG00000000669	-	76	86.310	Heterocephalus_glaber_female
ENSHCOG00000018918	srsf1a	66	86.905	ENSHGLG00000000600	-	76	86.310	Heterocephalus_glaber_female
ENSHCOG00000018918	srsf1a	97	81.928	ENSHGLG00100016906	-	78	87.310	Heterocephalus_glaber_male
ENSHCOG00000018918	srsf1a	77	87.817	ENSIPUG00000008750	srsf1b	78	84.772	Ictalurus_punctatus
ENSHCOG00000018918	srsf1a	78	87.065	ENSIPUG00000017039	srsf1a	80	89.055	Ictalurus_punctatus
ENSHCOG00000018918	srsf1a	97	81.928	ENSSTOG00000000243	-	96	84.264	Ictidomys_tridecemlineatus
ENSHCOG00000018918	srsf1a	50	77.953	ENSJJAG00000014464	-	92	79.688	Jaculus_jaculus
ENSHCOG00000018918	srsf1a	97	81.928	ENSJJAG00000000102	-	78	87.310	Jaculus_jaculus
ENSHCOG00000018918	srsf1a	78	92.462	ENSKMAG00000019232	srsf1a	79	89.447	Kryptolebias_marmoratus
ENSHCOG00000018918	srsf1a	88	85.714	ENSLBEG00000020864	-	84	89.447	Labrus_bergylta
ENSHCOG00000018918	srsf1a	77	79.695	ENSLBEG00000015294	-	79	77.665	Labrus_bergylta
ENSHCOG00000018918	srsf1a	77	84.772	ENSLACG00000014160	srsf1a	72	83.249	Latimeria_chalumnae
ENSHCOG00000018918	srsf1a	77	87.310	ENSLOCG00000005994	srsf1a	78	84.264	Lepisosteus_oculatus
ENSHCOG00000018918	srsf1a	77	87.817	ENSLAFG00000025743	SRSF1	78	87.310	Loxodonta_africana
ENSHCOG00000018918	srsf1a	97	81.928	ENSMFAG00000040003	-	95	88.406	Macaca_fascicularis
ENSHCOG00000018918	srsf1a	98	79.200	ENSMMUG00000003260	-	93	84.264	Macaca_mulatta
ENSHCOG00000018918	srsf1a	97	81.928	ENSMMUG00000004725	SRSF1	95	88.406	Macaca_mulatta
ENSHCOG00000018918	srsf1a	98	79.600	ENSMNEG00000015983	-	76	85.279	Macaca_nemestrina
ENSHCOG00000018918	srsf1a	97	81.928	ENSMNEG00000027680	-	95	88.406	Macaca_nemestrina
ENSHCOG00000018918	srsf1a	98	76.400	ENSMLEG00000015243	-	76	82.234	Mandrillus_leucophaeus
ENSHCOG00000018918	srsf1a	77	87.817	ENSMLEG00000040509	SRSF1	78	87.310	Mandrillus_leucophaeus
ENSHCOG00000018918	srsf1a	77	84.264	ENSMAMG00000019687	-	78	83.249	Mastacembelus_armatus
ENSHCOG00000018918	srsf1a	78	91.960	ENSMAMG00000018454	-	79	90.452	Mastacembelus_armatus
ENSHCOG00000018918	srsf1a	77	88.325	ENSMAMG00000019691	-	80	85.787	Mastacembelus_armatus
ENSHCOG00000018918	srsf1a	97	81.928	ENSMAUG00000021845	Srsf1	78	87.310	Mesocricetus_auratus
ENSHCOG00000018918	srsf1a	97	81.928	ENSMICG00000013639	-	95	88.406	Microcebus_murinus
ENSHCOG00000018918	srsf1a	97	81.928	ENSMOCG00000001996	Srsf1	78	87.310	Microtus_ochrogaster
ENSHCOG00000018918	srsf1a	88	86.161	ENSMMOG00000014354	srsf1a	84	89.447	Mola_mola
ENSHCOG00000018918	srsf1a	72	90.761	ENSMODG00000014781	-	62	90.761	Monodelphis_domestica
ENSHCOG00000018918	srsf1a	80	75.490	ENSMALG00000007763	-	77	76.650	Monopterus_albus
ENSHCOG00000018918	srsf1a	78	91.960	ENSMALG00000017129	-	76	88.945	Monopterus_albus
ENSHCOG00000018918	srsf1a	97	81.928	MGP_CAROLIEiJ_G0016943	Srsf1	90	88.108	Mus_caroli
ENSHCOG00000018918	srsf1a	97	81.928	ENSMUSG00000018379	Srsf1	90	88.108	Mus_musculus
ENSHCOG00000018918	srsf1a	97	81.928	MGP_PahariEiJ_G0018074	Srsf1	70	95.946	Mus_pahari
ENSHCOG00000018918	srsf1a	97	81.928	MGP_SPRETEiJ_G0017790	Srsf1	90	88.108	Mus_spretus
ENSHCOG00000018918	srsf1a	77	87.817	ENSMPUG00000015369	SRSF1	78	87.310	Mustela_putorius_furo
ENSHCOG00000018918	srsf1a	77	87.817	ENSMLUG00000011040	SRSF1	78	87.310	Myotis_lucifugus
ENSHCOG00000018918	srsf1a	79	80.788	ENSMLUG00000023995	-	77	80.711	Myotis_lucifugus
ENSHCOG00000018918	srsf1a	77	87.817	ENSNGAG00000011395	Srsf1	78	87.310	Nannospalax_galili
ENSHCOG00000018918	srsf1a	99	70.356	ENSNBRG00000008041	srsf1b	78	76.142	Neolamprologus_brichardi
ENSHCOG00000018918	srsf1a	97	81.928	ENSNLEG00000008088	-	95	88.406	Nomascus_leucogenys
ENSHCOG00000018918	srsf1a	53	86.029	ENSOPRG00000001234	-	72	85.294	Ochotona_princeps
ENSHCOG00000018918	srsf1a	97	81.928	ENSODEG00000011481	-	78	87.310	Octodon_degus
ENSHCOG00000018918	srsf1a	78	91.457	ENSONIG00000013160	-	78	89.500	Oreochromis_niloticus
ENSHCOG00000018918	srsf1a	78	87.500	ENSONIG00000004860	-	79	84.772	Oreochromis_niloticus
ENSHCOG00000018918	srsf1a	94	63.223	ENSOCUG00000010894	-	75	67.692	Oryctolagus_cuniculus
ENSHCOG00000018918	srsf1a	78	91.960	ENSORLG00000004580	srsf1a	79	90.452	Oryzias_latipes
ENSHCOG00000018918	srsf1a	88	86.607	ENSORLG00020009456	srsf1a	84	90.452	Oryzias_latipes_hni
ENSHCOG00000018918	srsf1a	88	86.607	ENSORLG00015014384	srsf1a	84	90.452	Oryzias_latipes_hsok
ENSHCOG00000018918	srsf1a	70	89.444	ENSOMEG00000004106	srsf1a	71	87.778	Oryzias_melastigma
ENSHCOG00000018918	srsf1a	81	88.462	ENSOGAG00000025950	-	78	87.310	Otolemur_garnettii
ENSHCOG00000018918	srsf1a	77	82.741	ENSOARG00000008323	SRSF1	77	82.741	Ovis_aries
ENSHCOG00000018918	srsf1a	97	81.928	ENSPPAG00000043403	-	95	88.406	Pan_paniscus
ENSHCOG00000018918	srsf1a	97	81.928	ENSPPRG00000004238	-	90	88.108	Panthera_pardus
ENSHCOG00000018918	srsf1a	97	81.928	ENSPTRG00000049077	SRSF1	95	88.406	Pan_troglodytes
ENSHCOG00000018918	srsf1a	97	81.928	ENSPANG00000022305	-	95	88.406	Papio_anubis
ENSHCOG00000018918	srsf1a	98	64.032	ENSPANG00000030275	-	75	64.500	Papio_anubis
ENSHCOG00000018918	srsf1a	77	87.817	ENSPKIG00000012857	srsf1b	78	84.772	Paramormyrops_kingsleyae
ENSHCOG00000018918	srsf1a	88	82.743	ENSPKIG00000007204	srsf1a	84	84.500	Paramormyrops_kingsleyae
ENSHCOG00000018918	srsf1a	77	80.905	ENSPSIG00000009000	-	78	79.695	Pelodiscus_sinensis
ENSHCOG00000018918	srsf1a	94	78.512	ENSPMGG00000013112	-	80	93.048	Periophthalmus_magnuspinnatus
ENSHCOG00000018918	srsf1a	79	82.673	ENSPMGG00000005467	-	79	82.412	Periophthalmus_magnuspinnatus
ENSHCOG00000018918	srsf1a	97	81.928	ENSPEMG00000021416	Srsf1	78	87.310	Peromyscus_maniculatus_bairdii
ENSHCOG00000018918	srsf1a	77	87.817	ENSPCIG00000006076	-	78	87.817	Phascolarctos_cinereus
ENSHCOG00000018918	srsf1a	79	84.236	ENSPFOG00000018325	-	70	82.412	Poecilia_formosa
ENSHCOG00000018918	srsf1a	79	84.236	ENSPLAG00000008416	srsf1b	80	82.412	Poecilia_latipinna
ENSHCOG00000018918	srsf1a	50	89.147	ENSPMEG00000020607	-	99	86.047	Poecilia_mexicana
ENSHCOG00000018918	srsf1a	79	84.236	ENSPMEG00000002388	-	80	82.412	Poecilia_mexicana
ENSHCOG00000018918	srsf1a	50	89.147	ENSPMEG00000014312	-	99	86.047	Poecilia_mexicana
ENSHCOG00000018918	srsf1a	78	91.960	ENSPREG00000009667	srsf1a	79	90.452	Poecilia_reticulata
ENSHCOG00000018918	srsf1a	97	81.928	ENSPPYG00000008240	SRSF1	78	87.310	Pongo_abelii
ENSHCOG00000018918	srsf1a	77	87.817	ENSPCAG00000005199	SRSF1	78	87.310	Procavia_capensis
ENSHCOG00000018918	srsf1a	97	81.928	ENSPCOG00000023654	-	95	88.406	Propithecus_coquereli
ENSHCOG00000018918	srsf1a	84	69.907	ENSPCOG00000025736	-	93	71.066	Propithecus_coquereli
ENSHCOG00000018918	srsf1a	51	94.286	ENSPVAG00000000519	-	53	94.286	Pteropus_vampyrus
ENSHCOG00000018918	srsf1a	77	85.787	ENSPNAG00000014601	srsf1b	78	84.264	Pygocentrus_nattereri
ENSHCOG00000018918	srsf1a	78	85.000	ENSPNAG00000022241	srsf1a	79	82.500	Pygocentrus_nattereri
ENSHCOG00000018918	srsf1a	77	87.817	ENSRNOG00000050323	Srsf1	78	87.310	Rattus_norvegicus
ENSHCOG00000018918	srsf1a	97	81.928	ENSRBIG00000034445	-	95	88.406	Rhinopithecus_bieti
ENSHCOG00000018918	srsf1a	97	81.928	ENSRROG00000041506	-	95	88.406	Rhinopithecus_roxellana
ENSHCOG00000018918	srsf1a	97	81.928	ENSSBOG00000025377	-	95	88.406	Saimiri_boliviensis_boliviensis
ENSHCOG00000018918	srsf1a	77	87.817	ENSSHAG00000002552	-	78	87.817	Sarcophilus_harrisii
ENSHCOG00000018918	srsf1a	77	87.817	ENSSFOG00015004800	srsf1a	77	84.772	Scleropages_formosus
ENSHCOG00000018918	srsf1a	77	85.000	ENSSMAG00000009719	-	78	85.500	Scophthalmus_maximus
ENSHCOG00000018918	srsf1a	78	90.452	ENSSMAG00000007018	-	79	87.940	Scophthalmus_maximus
ENSHCOG00000018918	srsf1a	98	71.713	ENSSDUG00000003929	-	83	77.387	Seriola_dumerili
ENSHCOG00000018918	srsf1a	88	85.714	ENSSDUG00000011303	-	84	89.447	Seriola_dumerili
ENSHCOG00000018918	srsf1a	78	90.955	ENSSLDG00000010543	-	79	89.447	Seriola_lalandi_dorsalis
ENSHCOG00000018918	srsf1a	89	70.175	ENSSLDG00000016895	-	79	78.238	Seriola_lalandi_dorsalis
ENSHCOG00000018918	srsf1a	77	77.778	ENSSLDG00000016868	-	76	77.778	Seriola_lalandi_dorsalis
ENSHCOG00000018918	srsf1a	72	85.870	ENSSARG00000010949	-	62	88.587	Sorex_araneus
ENSHCOG00000018918	srsf1a	97	81.526	ENSSPUG00000000804	-	91	87.568	Sphenodon_punctatus
ENSHCOG00000018918	srsf1a	78	92.965	ENSSPAG00000022562	-	79	91.457	Stegastes_partitus
ENSHCOG00000018918	srsf1a	77	84.466	ENSSPAG00000014152	-	80	83.495	Stegastes_partitus
ENSHCOG00000018918	srsf1a	97	81.928	ENSSSCG00000017626	-	78	87.310	Sus_scrofa
ENSHCOG00000018918	srsf1a	54	85.401	ENSTGUG00000008416	-	72	84.672	Taeniopygia_guttata
ENSHCOG00000018918	srsf1a	78	90.955	ENSTRUG00000003691	srsf1a	79	89.447	Takifugu_rubripes
ENSHCOG00000018918	srsf1a	78	90.955	ENSTNIG00000016223	srsf1a	79	89.000	Tetraodon_nigroviridis
ENSHCOG00000018918	srsf1a	72	86.957	ENSTBEG00000015378	-	62	86.413	Tupaia_belangeri
ENSHCOG00000018918	srsf1a	53	86.029	ENSTTRG00000007310	SRSF1	72	85.294	Tursiops_truncatus
ENSHCOG00000018918	srsf1a	77	87.817	ENSUAMG00000009858	SRSF1	78	87.310	Ursus_americanus
ENSHCOG00000018918	srsf1a	97	81.928	ENSUMAG00000000455	-	76	87.310	Ursus_maritimus
ENSHCOG00000018918	srsf1a	77	88.325	ENSVPAG00000010094	SRSF1	78	86.802	Vicugna_pacos
ENSHCOG00000018918	srsf1a	97	81.928	ENSVVUG00000011882	-	76	87.310	Vulpes_vulpes
ENSHCOG00000018918	srsf1a	77	85.279	ENSXETG00000008954	srsf1	79	83.491	Xenopus_tropicalis
ENSHCOG00000018918	srsf1a	78	91.960	ENSXMAG00000011766	srsf1a	79	90.452	Xiphophorus_maculatus