EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000000290 (Gene tree)
Gene ID: 16414
Gene Symbol: Itgb2
Alias: 2E6|Cd18|Mac-1 beta
Full Name: integrin beta 2
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 35457
Position: chr10: 77530252-77565708
Accession: 96611
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000156644	-	2411	-	ENSMUSP00000137865	56 (aa)	-	M0QWJ6
ENSMUST00000000299	-	2970	XM_006513271	ENSMUSP00000000299	770 (aa)	XP_006513334	Q542I8
ENSMUST00000153541	-	2619	-	ENSMUSP00000137734	480 (aa)	-	M0QWA7
ENSMUST00000131023	-	364	-	ENSMUSP00000119657	54 (aa)	-	D3Z1S4
ENSMUST00000130059	-	630	-	ENSMUSP00000118191	130 (aa)	-	D3YYP8

Gene Model

Click here to download ENSMUSG00000000290's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04015	Rap1 signaling pathway	KEGG
mmu04145	Phagosome	KEGG
mmu04390	Hippo signaling pathway	KEGG
mmu04514	Cell adhesion molecules (CAMs)	KEGG
mmu04610	Complement and coagulation cascades	KEGG
mmu04650	Natural killer cell mediated cytotoxicity	KEGG
mmu04670	Leukocyte transendothelial migration	KEGG
mmu04810	Regulation of actin cytoskeleton	KEGG
mmu05133	Pertussis	KEGG
mmu05134	Legionellosis	KEGG
mmu05140	Leishmaniasis	KEGG
mmu05144	Malaria	KEGG
mmu05146	Amoebiasis	KEGG
mmu05150	Staphylococcus aureus infection	KEGG
mmu05152	Tuberculosis	KEGG
mmu05166	Human T-cell leukemia virus 1 infection	KEGG
mmu05323	Rheumatoid arthritis	KEGG
mmu05416	Viral myocarditis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000000290's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000000290	Itgb2	99	45.500	ENSG00000150093	ITGB1	97	47.664	Homo_sapiens
ENSMUSG00000000290	Itgb2	97	48.665	ENSMUSG00000025809	Itgb1	96	46.512	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001540	amyloid-beta binding	21873635.	IBA	Function
GO:0001540	amyloid-beta binding	18981818.	IMP	Function
GO:0001851	complement component C3b binding	20199584.	IGI	Function
GO:0002523	leukocyte migration involved in inflammatory response	-	ISO	Process
GO:0005178	integrin binding	21873635.	IBA	Function
GO:0005515	protein binding	19234461.23395392.	IPI	Function
GO:0005886	plasma membrane	-	ISO	Component
GO:0005925	focal adhesion	21873635.	IBA	Component
GO:0006898	receptor-mediated endocytosis	20199584.	IMP	Process
GO:0006909	phagocytosis	-	IEA	Process
GO:0006911	phagocytosis, engulfment	20199584.	IMP	Process
GO:0007155	cell adhesion	19342649.	IGI	Process
GO:0007155	cell adhesion	10528208.	IMP	Process
GO:0007155	cell adhesion	-	ISO	Process
GO:0007159	leukocyte cell-cell adhesion	-	ISO	Process
GO:0007160	cell-matrix adhesion	21873635.	IBA	Process
GO:0007160	cell-matrix adhesion	-	ISO	Process
GO:0007229	integrin-mediated signaling pathway	21873635.	IBA	Process
GO:0007229	integrin-mediated signaling pathway	15249579.	IDA	Process
GO:0007229	integrin-mediated signaling pathway	-	ISO	Process
GO:0008305	integrin complex	21873635.	IBA	Component
GO:0009986	cell surface	21873635.	IBA	Component
GO:0009986	cell surface	17023661.	IDA	Component
GO:0009986	cell surface	23620790.	ISO	Component
GO:0016020	membrane	10601245.23395392.	IDA	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0016477	cell migration	21873635.	IBA	Process
GO:0019901	protein kinase binding	-	ISO	Function
GO:0030101	natural killer cell activation	-	ISO	Process
GO:0030369	ICAM-3 receptor activity	-	ISO	Function
GO:0030593	neutrophil chemotaxis	10528208.	IMP	Process
GO:0030593	neutrophil chemotaxis	-	ISO	Process
GO:0031072	heat shock protein binding	-	ISO	Function
GO:0031623	receptor internalization	23395392.	IDA	Process
GO:0032930	positive regulation of superoxide anion generation	-	ISO	Process
GO:0033627	cell adhesion mediated by integrin	21873635.	IBA	Process
GO:0034113	heterotypic cell-cell adhesion	-	ISO	Process
GO:0034687	integrin alphaL-beta2 complex	-	ISO	Component
GO:0034688	integrin alphaM-beta2 complex	20199584.	IMP	Component
GO:0038023	signaling receptor activity	-	IEA	Function
GO:0038024	cargo receptor activity	20199584.	IMP	Function
GO:0043113	receptor clustering	-	ISO	Process
GO:0043235	receptor complex	23382219.	ISO	Component
GO:0043315	positive regulation of neutrophil degranulation	-	ISO	Process
GO:0043542	endothelial cell migration	-	ISO	Process
GO:0044853	plasma membrane raft	-	ISO	Component
GO:0044877	protein-containing complex binding	-	ISO	Function
GO:0045121	membrane raft	10601245.	IDA	Component
GO:0045123	cellular extravasation	10528208.	IMP	Process
GO:0045123	cellular extravasation	-	ISO	Process
GO:0045429	positive regulation of nitric oxide biosynthetic process	-	ISO	Process
GO:0045766	positive regulation of angiogenesis	-	ISO	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0046982	protein heterodimerization activity	-	ISO	Function
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	-	ISO	Process
GO:0050798	activated T cell proliferation	15210787.	IMP	Process
GO:0050839	cell adhesion molecule binding	-	ISO	Function
GO:0050839	cell adhesion molecule binding	-	ISO	Function
GO:0051092	positive regulation of NF-kappaB transcription factor activity	-	ISO	Process
GO:0071404	cellular response to low-density lipoprotein particle stimulus	23395392.	IDA	Process
GO:0097242	amyloid-beta clearance	20199584.	IMP	Process
GO:0098609	cell-cell adhesion	12652296.16093349.	IGI	Process
GO:0098609	cell-cell adhesion	-	ISO	Process
GO:0099568	cytoplasmic region	-	ISO	Component
GO:1990266	neutrophil migration	-	ISO	Process