EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000000628 (Gene tree)
Gene ID: 15277
Gene Symbol: Hk2
Alias: HKII
Full Name: hexokinase 2
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 49430
Position: chr6: 82725025-82774454
Accession: 1315197
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000170833	-	2792	XM_017321401	ENSMUSP00000125986	889 (aa)	XP_017176890	E9Q5B5
ENSMUST00000168725	-	594	-	-	- (aa)	-	-
ENSMUST00000000642	-	5513	-	ENSMUSP00000000642	917 (aa)	-	O08528
ENSMUST00000169270	-	505	-	ENSMUSP00000128572	43 (aa)	-	E9Q9M6

Gene Model

Click here to download ENSMUSG00000000628's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu00010	Glycolysis / Gluconeogenesis	KEGG
mmu00051	Fructose and mannose metabolism	KEGG
mmu00052	Galactose metabolism	KEGG
mmu00500	Starch and sucrose metabolism	KEGG
mmu00520	Amino sugar and nucleotide sugar metabolism	KEGG
mmu00524	Neomycin, kanamycin and gentamicin biosynthesis	KEGG
mmu01100	Metabolic pathways	KEGG
mmu01200	Carbon metabolism	KEGG
mmu04066	HIF-1 signaling pathway	KEGG
mmu04910	Insulin signaling pathway	KEGG
mmu04930	Type II diabetes mellitus	KEGG
mmu04973	Carbohydrate digestion and absorption	KEGG
mmu05230	Central carbon metabolism in cancer	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000000628's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000000628	Hk2	100	97.674	ENSG00000159399	HK2	100	94.713	Homo_sapiens
ENSMUSG00000000628	Hk2	99	73.982	ENSG00000156515	HK1	99	73.982	Homo_sapiens
ENSMUSG00000000628	Hk2	96	35.347	YFR053C		91	35.463	Saccharomyces_cerevisiae
ENSMUSG00000000628	Hk2	94	33.410	YGL253W	HXK2	94	33.475	Saccharomyces_cerevisiae
ENSMUSG00000000628	Hk2	98	36.175	YCL040W	GLK1	99	36.175	Saccharomyces_cerevisiae
ENSMUSG00000000628	Hk2	96	35.865	YDR516C		95	35.865	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0001678	cellular glucose homeostasis	21873635.	IBA	Process
GO:0002931	response to ischemia	-	ISO	Process
GO:0003824	catalytic activity	-	IEA	Function
GO:0004340	glucokinase activity	21873635.	IBA	Function
GO:0004396	hexokinase activity	18165236.	IDA	Function
GO:0004396	hexokinase activity	10428828.	IMP	Function
GO:0004396	hexokinase activity	-	ISO	Function
GO:0005515	protein binding	22233811.	IPI	Function
GO:0005524	ATP binding	-	ISO	Function
GO:0005536	glucose binding	-	ISO	Function
GO:0005739	mitochondrion	18614015.	HDA	Component
GO:0005739	mitochondrion	-	ISO	Component
GO:0005741	mitochondrial outer membrane	-	ISO	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005886	plasma membrane	-	ISO	Component
GO:0005975	carbohydrate metabolic process	-	IEA	Process
GO:0006006	glucose metabolic process	10428828.	IMP	Process
GO:0006096	glycolytic process	21873635.	IBA	Process
GO:0008152	metabolic process	-	IEA	Process
GO:0008637	apoptotic mitochondrial changes	18350175.	IGI	Process
GO:0008637	apoptotic mitochondrial changes	-	ISO	Process
GO:0008865	fructokinase activity	21873635.	IBA	Function
GO:0016301	kinase activity	-	IEA	Function
GO:0016310	phosphorylation	-	IEA	Process
GO:0016529	sarcoplasmic reticulum	-	ISO	Component
GO:0016740	transferase activity	-	IEA	Function
GO:0016773	phosphotransferase activity, alcohol group as acceptor	-	IEA	Function
GO:0019158	mannokinase activity	21873635.	IBA	Function
GO:0035795	negative regulation of mitochondrial membrane permeability	22517678.	IMP	Process
GO:0045766	positive regulation of angiogenesis	-	ISO	Process
GO:0046324	regulation of glucose import	17639019.	IMP	Process
GO:0046835	carbohydrate phosphorylation	10428828.	IMP	Process
GO:0046835	carbohydrate phosphorylation	-	ISO	Process
GO:0072655	establishment of protein localization to mitochondrion	-	ISO	Process
GO:0072656	maintenance of protein location in mitochondrion	-	ISO	Process
GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	-	ISO	Process
GO:1990830	cellular response to leukemia inhibitory factor	20439489.	IEP	Process
GO:2000378	negative regulation of reactive oxygen species metabolic process	22517678.	IMP	Process