EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000001440 (Gene tree)
Gene ID: 16211
Gene Symbol: Kpnb1
Alias: Impnb
Full Name: karyopherin (importin) beta 1
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Minus strand
Length: 28168 bases
Position: chr11:97159714-97187881
Accession: 107532
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000001479	IBN_N	PF03810.19	1.6e-11	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000001479	-	5894	-	ENSMUSP00000001479	876 (aa)	-	P70168
ENSMUST00000132633	-	643	-	-	- (aa)	-	-
ENSMUST00000153727	-	779	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000001440's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03013	RNA transport	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000001440's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000001440	Kpnb1	100	99.201	ENSG00000108424	KPNB1	100	100.000	Homo_sapiens
ENSMUSG00000001440	Kpnb1	100	93.037	ENSAPOG00000020572	kpnb1	100	93.037	Acanthochromis_polyacanthus
ENSMUSG00000001440	Kpnb1	96	99.052	ENSAMEG00000004613	KPNB1	100	99.052	Ailuropoda_melanoleuca
ENSMUSG00000001440	Kpnb1	98	92.874	ENSACIG00000023130	kpnb1	99	92.874	Amphilophus_citrinellus
ENSMUSG00000001440	Kpnb1	100	93.037	ENSAOCG00000007048	kpnb1	100	93.037	Amphiprion_ocellaris
ENSMUSG00000001440	Kpnb1	100	93.037	ENSAPEG00000008270	kpnb1	100	93.037	Amphiprion_percula
ENSMUSG00000001440	Kpnb1	100	92.466	ENSATEG00000015139	kpnb1	100	92.466	Anabas_testudineus
ENSMUSG00000001440	Kpnb1	99	94.863	ENSAPLG00000010177	KPNB1	100	94.863	Anas_platyrhynchos
ENSMUSG00000001440	Kpnb1	100	97.032	ENSACAG00000007097	KPNB1	100	97.032	Anolis_carolinensis
ENSMUSG00000001440	Kpnb1	100	96.461	ENSANAG00000024932	-	99	96.461	Aotus_nancymaae
ENSMUSG00000001440	Kpnb1	100	92.922	ENSACLG00000015070	kpnb1	100	92.922	Astatotilapia_calliptera
ENSMUSG00000001440	Kpnb1	100	93.037	ENSAMXG00000041903	kpnb1	100	93.037	Astyanax_mexicanus
ENSMUSG00000001440	Kpnb1	100	99.315	ENSBTAG00000006586	KPNB1	100	99.315	Bos_taurus
ENSMUSG00000001440	Kpnb1	99	48.077	WBGene00002075	imb-1	98	48.077	Caenorhabditis_elegans
ENSMUSG00000001440	Kpnb1	100	99.087	ENSCJAG00000007834	KPNB1	100	99.087	Callithrix_jacchus
ENSMUSG00000001440	Kpnb1	100	99.315	ENSCAFG00000016678	KPNB1	100	99.315	Canis_familiaris
ENSMUSG00000001440	Kpnb1	100	99.315	ENSCAFG00020023205	KPNB1	100	99.315	Canis_lupus_dingo
ENSMUSG00000001440	Kpnb1	100	99.315	ENSCHIG00000014896	KPNB1	100	99.315	Capra_hircus
ENSMUSG00000001440	Kpnb1	100	97.032	ENSTSYG00000014472	KPNB1	99	97.032	Carlito_syrichta
ENSMUSG00000001440	Kpnb1	96	99.288	ENSCAPG00000014185	KPNB1	100	99.288	Cavia_aperea
ENSMUSG00000001440	Kpnb1	100	99.315	ENSCPOG00000006566	KPNB1	100	99.315	Cavia_porcellus
ENSMUSG00000001440	Kpnb1	100	79.038	ENSCCAG00000018551	-	100	79.038	Cebus_capucinus
ENSMUSG00000001440	Kpnb1	100	92.255	ENSCCAG00000029263	-	99	92.255	Cebus_capucinus
ENSMUSG00000001440	Kpnb1	100	99.201	ENSCATG00000037124	KPNB1	100	99.201	Cercocebus_atys
ENSMUSG00000001440	Kpnb1	100	99.201	ENSCLAG00000017091	KPNB1	100	99.201	Chinchilla_lanigera
ENSMUSG00000001440	Kpnb1	100	99.201	ENSCSAG00000002605	KPNB1	100	99.201	Chlorocebus_sabaeus
ENSMUSG00000001440	Kpnb1	73	100.000	ENSCHOG00000010604	KPNB1	73	100.000	Choloepus_hoffmanni
ENSMUSG00000001440	Kpnb1	99	98.030	ENSCPBG00000027423	KPNB1	94	98.030	Chrysemys_picta_bellii
ENSMUSG00000001440	Kpnb1	99	64.538	ENSCING00000004639	-	99	64.538	Ciona_intestinalis
ENSMUSG00000001440	Kpnb1	100	62.260	ENSCSAVG00000008624	-	100	62.260	Ciona_savignyi
ENSMUSG00000001440	Kpnb1	96	96.948	ENSCANG00000013489	KPNB1	100	96.948	Colobus_angolensis_palliatus
ENSMUSG00000001440	Kpnb1	100	99.886	ENSCGRG00001016042	Kpnb1	100	99.886	Cricetulus_griseus_chok1gshd
ENSMUSG00000001440	Kpnb1	96	99.881	ENSCGRG00000013910	Kpnb1	100	99.881	Cricetulus_griseus_crigri
ENSMUSG00000001440	Kpnb1	97	90.258	ENSCSEG00000007991	kpnb1	100	90.258	Cynoglossus_semilaevis
ENSMUSG00000001440	Kpnb1	100	92.237	ENSDARG00000104889	kpnb1	100	92.237	Danio_rerio
ENSMUSG00000001440	Kpnb1	99	61.758	FBgn0262743	Fs(2)Ket	99	61.758	Drosophila_melanogaster
ENSMUSG00000001440	Kpnb1	98	82.367	ENSEBUG00000013869	kpnb1	98	82.367	Eptatretus_burgeri
ENSMUSG00000001440	Kpnb1	100	99.315	ENSEASG00005000805	KPNB1	100	99.315	Equus_asinus_asinus
ENSMUSG00000001440	Kpnb1	100	99.315	ENSECAG00000014560	KPNB1	100	99.315	Equus_caballus
ENSMUSG00000001440	Kpnb1	85	98.492	ENSEEUG00000005046	KPNB1	88	98.492	Erinaceus_europaeus
ENSMUSG00000001440	Kpnb1	100	93.037	ENSELUG00000015847	kpnb1	100	93.037	Esox_lucius
ENSMUSG00000001440	Kpnb1	100	99.315	ENSFCAG00000023994	KPNB1	100	99.315	Felis_catus
ENSMUSG00000001440	Kpnb1	96	99.288	ENSFDAG00000019923	KPNB1	100	99.288	Fukomys_damarensis
ENSMUSG00000001440	Kpnb1	100	92.352	ENSFHEG00000020199	kpnb1	100	92.352	Fundulus_heteroclitus
ENSMUSG00000001440	Kpnb1	100	88.128	ENSGMOG00000011607	kpnb1	99	88.128	Gadus_morhua
ENSMUSG00000001440	Kpnb1	100	97.374	ENSGALG00000036962	KPNB1	100	97.374	Gallus_gallus
ENSMUSG00000001440	Kpnb1	100	92.237	ENSGAFG00000000783	kpnb1	100	92.237	Gambusia_affinis
ENSMUSG00000001440	Kpnb1	100	88.588	ENSGACG00000014765	kpnb1	100	88.588	Gasterosteus_aculeatus
ENSMUSG00000001440	Kpnb1	96	97.741	ENSGAGG00000023737	KPNB1	92	97.741	Gopherus_agassizii
ENSMUSG00000001440	Kpnb1	100	99.201	ENSGGOG00000008089	KPNB1	100	99.201	Gorilla_gorilla
ENSMUSG00000001440	Kpnb1	100	92.922	ENSHBUG00000016826	kpnb1	100	92.922	Haplochromis_burtoni
ENSMUSG00000001440	Kpnb1	100	99.315	ENSHGLG00000014138	KPNB1	100	99.315	Heterocephalus_glaber_female
ENSMUSG00000001440	Kpnb1	98	97.796	ENSHGLG00100006572	KPNB1	100	99.288	Heterocephalus_glaber_male
ENSMUSG00000001440	Kpnb1	100	91.324	ENSHCOG00000002084	kpnb1	100	91.324	Hippocampus_comes
ENSMUSG00000001440	Kpnb1	99	88.876	ENSIPUG00000012402	kpnb1	95	88.876	Ictalurus_punctatus
ENSMUSG00000001440	Kpnb1	100	99.543	ENSSTOG00000007896	KPNB1	100	99.543	Ictidomys_tridecemlineatus
ENSMUSG00000001440	Kpnb1	100	99.429	ENSJJAG00000010909	Kpnb1	100	99.429	Jaculus_jaculus
ENSMUSG00000001440	Kpnb1	100	92.009	ENSKMAG00000001547	kpnb1	100	92.009	Kryptolebias_marmoratus
ENSMUSG00000001440	Kpnb1	99	92.734	ENSLBEG00000025794	kpnb1	99	91.228	Labrus_bergylta
ENSMUSG00000001440	Kpnb1	88	94.682	ENSLACG00000017620	KPNB1	99	94.682	Latimeria_chalumnae
ENSMUSG00000001440	Kpnb1	100	93.607	ENSLOCG00000013753	kpnb1	100	93.607	Lepisosteus_oculatus
ENSMUSG00000001440	Kpnb1	100	93.836	ENSLAFG00000001328	KPNB1	100	93.836	Loxodonta_africana
ENSMUSG00000001440	Kpnb1	99	96.564	ENSMFAG00000030197	KPNB1	100	99.170	Macaca_fascicularis
ENSMUSG00000001440	Kpnb1	99	97.486	ENSMMUG00000019760	KPNB1	99	97.486	Macaca_mulatta
ENSMUSG00000001440	Kpnb1	100	99.201	ENSMNEG00000040927	KPNB1	100	99.201	Macaca_nemestrina
ENSMUSG00000001440	Kpnb1	96	99.170	ENSMLEG00000038185	KPNB1	96	99.170	Mandrillus_leucophaeus
ENSMUSG00000001440	Kpnb1	100	93.037	ENSMAMG00000011036	kpnb1	100	93.037	Mastacembelus_armatus
ENSMUSG00000001440	Kpnb1	100	92.922	ENSMZEG00005004564	kpnb1	100	92.922	Maylandia_zebra
ENSMUSG00000001440	Kpnb1	55	97.516	ENSMGAG00000002770	-	100	97.516	Meleagris_gallopavo
ENSMUSG00000001440	Kpnb1	100	99.886	ENSMAUG00000006211	Kpnb1	100	99.886	Mesocricetus_auratus
ENSMUSG00000001440	Kpnb1	100	99.315	ENSMICG00000012059	KPNB1	84	99.315	Microcebus_murinus
ENSMUSG00000001440	Kpnb1	100	99.886	ENSMOCG00000003683	Kpnb1	100	99.886	Microtus_ochrogaster
ENSMUSG00000001440	Kpnb1	100	98.288	ENSMODG00000012505	KPNB1	100	98.288	Monodelphis_domestica
ENSMUSG00000001440	Kpnb1	100	93.151	ENSMALG00000000863	kpnb1	100	93.151	Monopterus_albus
ENSMUSG00000001440	Kpnb1	94	100.000	MGP_CAROLIEiJ_G0017050	Kpnb1	100	100.000	Mus_caroli
ENSMUSG00000001440	Kpnb1	100	98.290	ENSMPUG00000015220	KPNB1	100	98.290	Mustela_putorius_furo
ENSMUSG00000001440	Kpnb1	100	93.970	ENSMLUG00000014522	KPNB1	100	93.970	Myotis_lucifugus
ENSMUSG00000001440	Kpnb1	96	99.644	ENSNGAG00000017610	Kpnb1	100	99.644	Nannospalax_galili
ENSMUSG00000001440	Kpnb1	100	92.922	ENSNBRG00000019305	kpnb1	100	92.922	Neolamprologus_brichardi
ENSMUSG00000001440	Kpnb1	100	99.201	ENSNLEG00000001446	KPNB1	100	99.201	Nomascus_leucogenys
ENSMUSG00000001440	Kpnb1	100	92.694	ENSMEUG00000014284	KPNB1	100	92.694	Notamacropus_eugenii
ENSMUSG00000001440	Kpnb1	100	98.973	ENSODEG00000017287	KPNB1	100	98.973	Octodon_degus
ENSMUSG00000001440	Kpnb1	100	93.037	ENSONIG00000009269	kpnb1	100	93.037	Oreochromis_niloticus
ENSMUSG00000001440	Kpnb1	100	99.315	ENSOCUG00000015425	KPNB1	100	99.315	Oryctolagus_cuniculus
ENSMUSG00000001440	Kpnb1	100	92.922	ENSORLG00000019936	kpnb1	100	92.922	Oryzias_latipes
ENSMUSG00000001440	Kpnb1	100	92.922	ENSORLG00020021181	kpnb1	100	92.922	Oryzias_latipes_hni
ENSMUSG00000001440	Kpnb1	100	92.808	ENSORLG00015012177	kpnb1	100	92.808	Oryzias_latipes_hsok
ENSMUSG00000001440	Kpnb1	100	93.037	ENSOMEG00000021022	kpnb1	100	93.037	Oryzias_melastigma
ENSMUSG00000001440	Kpnb1	100	99.201	ENSOGAG00000006153	KPNB1	100	99.201	Otolemur_garnettii
ENSMUSG00000001440	Kpnb1	97	98.244	ENSOARG00000008469	KPNB1	99	98.244	Ovis_aries
ENSMUSG00000001440	Kpnb1	100	99.201	ENSPPAG00000028842	KPNB1	100	99.201	Pan_paniscus
ENSMUSG00000001440	Kpnb1	99	96.670	ENSPPRG00000022879	KPNB1	99	96.670	Panthera_pardus
ENSMUSG00000001440	Kpnb1	99	96.670	ENSPTIG00000006870	KPNB1	99	96.670	Panthera_tigris_altaica
ENSMUSG00000001440	Kpnb1	100	99.201	ENSPTRG00000009333	KPNB1	100	99.201	Pan_troglodytes
ENSMUSG00000001440	Kpnb1	100	99.201	ENSPANG00000022099	KPNB1	100	99.201	Papio_anubis
ENSMUSG00000001440	Kpnb1	100	93.151	ENSPKIG00000017563	kpnb1	100	93.151	Paramormyrops_kingsleyae
ENSMUSG00000001440	Kpnb1	96	98.221	ENSPSIG00000009775	KPNB1	100	98.221	Pelodiscus_sinensis
ENSMUSG00000001440	Kpnb1	100	88.255	ENSPMGG00000001041	kpnb1	93	88.255	Periophthalmus_magnuspinnatus
ENSMUSG00000001440	Kpnb1	100	99.886	ENSPEMG00000017783	Kpnb1	100	99.886	Peromyscus_maniculatus_bairdii
ENSMUSG00000001440	Kpnb1	99	86.219	ENSPMAG00000007117	kpnb1	99	86.219	Petromyzon_marinus
ENSMUSG00000001440	Kpnb1	100	98.288	ENSPCIG00000001034	KPNB1	100	98.288	Phascolarctos_cinereus
ENSMUSG00000001440	Kpnb1	100	92.237	ENSPFOG00000009014	kpnb1	100	92.237	Poecilia_formosa
ENSMUSG00000001440	Kpnb1	100	92.237	ENSPLAG00000010922	kpnb1	100	92.237	Poecilia_latipinna
ENSMUSG00000001440	Kpnb1	100	92.237	ENSPREG00000012268	kpnb1	100	92.237	Poecilia_reticulata
ENSMUSG00000001440	Kpnb1	100	98.744	ENSPPYG00000025935	KPNB1	100	98.744	Pongo_abelii
ENSMUSG00000001440	Kpnb1	75	82.333	ENSPCAG00000002526	KPNB1	78	82.333	Procavia_capensis
ENSMUSG00000001440	Kpnb1	100	99.315	ENSPCOG00000026259	KPNB1	100	99.315	Propithecus_coquereli
ENSMUSG00000001440	Kpnb1	100	98.858	ENSPVAG00000004910	KPNB1	100	98.858	Pteropus_vampyrus
ENSMUSG00000001440	Kpnb1	100	88.755	ENSPNYG00000017703	kpnb1	96	93.495	Pundamilia_nyererei
ENSMUSG00000001440	Kpnb1	99	84.880	ENSPNAG00000024047	kpnb1	98	84.880	Pygocentrus_nattereri
ENSMUSG00000001440	Kpnb1	100	100.000	ENSRNOG00000009275	Kpnb1	100	100.000	Rattus_norvegicus
ENSMUSG00000001440	Kpnb1	100	98.973	ENSRBIG00000002254	KPNB1	99	98.973	Rhinopithecus_bieti
ENSMUSG00000001440	Kpnb1	99	98.730	ENSRROG00000030419	KPNB1	99	98.730	Rhinopithecus_roxellana
ENSMUSG00000001440	Kpnb1	99	34.016	YLR347C	KAP95	99	33.902	Saccharomyces_cerevisiae
ENSMUSG00000001440	Kpnb1	100	99.201	ENSSBOG00000030025	KPNB1	94	99.201	Saimiri_boliviensis_boliviensis
ENSMUSG00000001440	Kpnb1	96	97.993	ENSSHAG00000018214	KPNB1	100	97.993	Sarcophilus_harrisii
ENSMUSG00000001440	Kpnb1	100	93.721	ENSSFOG00015020000	kpnb1	100	93.721	Scleropages_formosus
ENSMUSG00000001440	Kpnb1	100	93.265	ENSSDUG00000016218	kpnb1	100	93.265	Seriola_dumerili
ENSMUSG00000001440	Kpnb1	98	93.240	ENSSLDG00000021549	kpnb1	97	93.240	Seriola_lalandi_dorsalis
ENSMUSG00000001440	Kpnb1	100	97.374	ENSSPUG00000017799	KPNB1	100	97.374	Sphenodon_punctatus
ENSMUSG00000001440	Kpnb1	100	93.037	ENSSPAG00000019346	kpnb1	100	93.037	Stegastes_partitus
ENSMUSG00000001440	Kpnb1	100	99.315	ENSSSCG00000017514	KPNB1	100	99.315	Sus_scrofa
ENSMUSG00000001440	Kpnb1	96	92.764	ENSTGUG00000003387	KPNB1	100	92.764	Taeniopygia_guttata
ENSMUSG00000001440	Kpnb1	100	90.411	ENSTRUG00000000542	kpnb1	100	90.411	Takifugu_rubripes
ENSMUSG00000001440	Kpnb1	100	90.639	ENSTNIG00000006494	kpnb1	100	90.639	Tetraodon_nigroviridis
ENSMUSG00000001440	Kpnb1	96	99.170	ENSTTRG00000004682	KPNB1	100	99.170	Tursiops_truncatus
ENSMUSG00000001440	Kpnb1	100	99.315	ENSUAMG00000025344	KPNB1	99	99.315	Ursus_americanus
ENSMUSG00000001440	Kpnb1	98	98.023	ENSUMAG00000016471	KPNB1	98	98.023	Ursus_maritimus
ENSMUSG00000001440	Kpnb1	100	84.817	ENSVPAG00000003675	KPNB1	100	84.817	Vicugna_pacos
ENSMUSG00000001440	Kpnb1	100	99.315	ENSVVUG00000003085	KPNB1	100	99.315	Vulpes_vulpes
ENSMUSG00000001440	Kpnb1	100	94.863	ENSXETG00000014717	kpnb1	100	94.863	Xenopus_tropicalis
ENSMUSG00000001440	Kpnb1	100	92.352	ENSXMAG00000018792	kpnb1	100	92.352	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	10891500.11809816.15719015.17548362.18845677.19581287.23055941.25946333.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005635	nuclear envelope	-	ISO	Component
GO:0005643	nuclear pore	-	ISO	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0006606	protein import into nucleus	15689618.	IDA	Process
GO:0006606	protein import into nucleus	15964792.	ISO	Process
GO:0006607	NLS-bearing protein import into nucleus	21873635.	IBA	Process
GO:0006610	ribosomal protein import into nucleus	21873635.	IBA	Process
GO:0006610	ribosomal protein import into nucleus	11809816.	IDA	Process
GO:0006610	ribosomal protein import into nucleus	-	ISO	Process
GO:0006886	intracellular protein transport	-	IEA	Process
GO:0007079	mitotic chromosome movement towards spindle pole	-	ISO	Process
GO:0007080	mitotic metaphase plate congression	-	ISO	Process
GO:0008139	nuclear localization sequence binding	21873635.	IBA	Function
GO:0008536	Ran GTPase binding	-	IEA	Function
GO:0008565	protein transporter activity	21873635.	IBA	Function
GO:0008565	protein transporter activity	11809816.15689618.	IDA	Function
GO:0010494	cytoplasmic stress granule	27430620.	IDA	Component
GO:0015031	protein transport	-	IEA	Process
GO:0019894	kinesin binding	-	ISO	Function
GO:0019899	enzyme binding	-	ISO	Function
GO:0019904	protein domain specific binding	-	ISO	Function
GO:0030953	astral microtubule organization	-	ISO	Process
GO:0031291	Ran protein signal transduction	-	ISO	Process
GO:0031965	nuclear membrane	21873635.	IBA	Component
GO:0031965	nuclear membrane	-	ISO	Component
GO:0032991	protein-containing complex	19796622.	IDA	Component
GO:0034399	nuclear periphery	21873635.	IBA	Component
GO:0040001	establishment of mitotic spindle localization	-	ISO	Process
GO:0044877	protein-containing complex binding	-	ISO	Function
GO:0045184	establishment of protein localization	-	ISO	Process
GO:0051879	Hsp90 protein binding	19581287.	IDA	Function
GO:0061676	importin-alpha family protein binding	20699224.	IPI	Function
GO:0071782	endoplasmic reticulum tubular network	-	ISO	Component
GO:0090307	mitotic spindle assembly	-	ISO	Process