EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000003119 (Gene tree)
Gene ID: 69131
Gene Symbol: Cdk12
Alias: 1810022J16Rik|Crk7|Crkrs|D11Ertd752e
Full Name: cyclin-dependent kinase 12
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 75446
Position: chr11: 98203059-98278504
Accession: 1098802
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000147441	-	2605	-	-	- (aa)	-	-
ENSMUST00000003203	-	4837	XM_011249225	ENSMUSP00000003203	1258 (aa)	XP_011247527	Q14AX6
ENSMUST00000125152	-	443	-	-	- (aa)	-	-
ENSMUST00000145113	-	3648	-	-	- (aa)	-	-
ENSMUST00000107539	-	5912	-	ENSMUSP00000103163	1475 (aa)	-	Q14AX6
ENSMUST00000107538	-	5143	XM_006534108	ENSMUSP00000103162	1484 (aa)	XP_006534171	Q14AX6

Gene Model

Click here to download ENSMUSG00000003119's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000003119's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000003119	Cdk12	100	90.268	ENSG00000167258	CDK12	100	90.201	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0000307	cyclin-dependent protein kinase holoenzyme complex	21873635.	IBA	Component
GO:0000790	nuclear chromatin	21873635.	IBA	Component
GO:0001650	fibrillar center	-	ISO	Component
GO:0002944	cyclin K-CDK12 complex	-	ISO	Component
GO:0004672	protein kinase activity	-	ISO	Function
GO:0004674	protein serine/threonine kinase activity	-	IEA	Function
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	21873635.	IBA	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005694	chromosome	21873635.	IBA	Component
GO:0006368	transcription elongation from RNA polymerase II promoter	21873635.	IBA	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0006468	protein phosphorylation	21873635.	IBA	Process
GO:0008024	cyclin/CDK positive transcription elongation factor complex	21873635.	IBA	Component
GO:0008134	transcription factor binding	21873635.	IBA	Function
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	21873635.	IBA	Function
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	-	ISO	Function
GO:0008380	RNA splicing	-	ISO	Process
GO:0016301	kinase activity	-	IEA	Function
GO:0016310	phosphorylation	-	IEA	Process
GO:0016607	nuclear speck	-	ISO	Component
GO:0016740	transferase activity	-	IEA	Function
GO:0019901	protein kinase binding	22547058.	IDA	Function
GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex	-	ISO	Component
GO:0030332	cyclin binding	21873635.	IBA	Function
GO:0030332	cyclin binding	-	ISO	Function
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	21873635.	IBA	Process
GO:0043405	regulation of MAP kinase activity	-	ISO	Process
GO:0043484	regulation of RNA splicing	-	ISO	Process
GO:0044212	transcription regulatory region DNA binding	21873635.	IBA	Function
GO:0045944	positive regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0046777	protein autophosphorylation	-	ISO	Process
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	21873635.	IBA	Process
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	-	ISO	Process
GO:2000737	negative regulation of stem cell differentiation	22547058.	IMP	Process