EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000004099 (Gene tree)
Gene ID: 13433
Gene Symbol: Dnmt1
Alias: Cxxc9|Dnmt1o|MTase|MommeD2
Full Name: DNA methyltransferase (cytosine-5) 1
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 52680
Position: chr9: 20907209-20959888
Accession: 94912
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000004202	-	5367	XM_006509988	ENSMUSP00000004202	1620 (aa)	XP_006510051	P13864
ENSMUST00000216135	-	693	-	-	- (aa)	-	-
ENSMUST00000214964	-	1252	-	-	- (aa)	-	-
ENSMUST00000178110	-	5870	-	ENSMUSP00000136669	1501 (aa)	-	J3QNW0
ENSMUST00000216540	-	5543	XM_011242393	ENSMUSP00000150433	1502 (aa)	XP_011240695	P13864
ENSMUST00000215545	-	607	-	-	- (aa)	-	-
ENSMUST00000177754	-	5248	-	ENSMUSP00000136982	1501 (aa)	-	J3QNW0

Gene Model

Click here to download ENSMUSG00000004099's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu00270	Cysteine and methionine metabolism	KEGG
mmu01100	Metabolic pathways	KEGG
mmu05206	MicroRNAs in cancer	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000004099's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000004099	Dnmt1	100	77.483	ENSG00000130816	DNMT1	100	85.000	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	16887828.24105743.	IMP	Process
GO:0000792	heterochromatin	14519686.	IDA	Component
GO:0003677	DNA binding	21873635.	IBA	Function
GO:0003677	DNA binding	11399088.	IDA	Function
GO:0003677	DNA binding	-	ISO	Function
GO:0003682	chromatin binding	24105743.	IDA	Function
GO:0003723	RNA binding	20573698.	IDA	Function
GO:0003824	catalytic activity	-	IEA	Function
GO:0003886	DNA (cytosine-5-)-methyltransferase activity	21873635.	IBA	Function
GO:0003886	DNA (cytosine-5-)-methyltransferase activity	11399088.	IDA	Function
GO:0003886	DNA (cytosine-5-)-methyltransferase activity	-	ISO	Function
GO:0005515	protein binding	10615135.10888872.15550930.16085498.17931718.17994007.21268065.24335282.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	11942627.15063176.16424344.17931718.	IDA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005657	replication fork	10888872.	IDA	Component
GO:0005721	pericentric heterochromatin	17576694.	IDA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0006306	DNA methylation	11399088.	IDA	Process
GO:0006306	DNA methylation	16887828.24105743.	IMP	Process
GO:0006325	chromatin organization	-	IEA	Process
GO:0007265	Ras protein signal transduction	-	ISO	Process
GO:0008152	metabolic process	-	IEA	Process
GO:0008168	methyltransferase activity	10615135.	IDA	Function
GO:0008270	zinc ion binding	11399088.	IDA	Function
GO:0008327	methyl-CpG binding	20573698.	IDA	Function
GO:0009008	DNA-methyltransferase activity	-	ISO	Function
GO:0010216	maintenance of DNA methylation	21873635.	IBA	Process
GO:0010216	maintenance of DNA methylation	17576694.	IMP	Process
GO:0010216	maintenance of DNA methylation	-	ISO	Process
GO:0010424	DNA methylation on cytosine within a CG sequence	21873635.	IBA	Process
GO:0010424	DNA methylation on cytosine within a CG sequence	-	ISO	Process
GO:0010468	regulation of gene expression	16491076.23028046.	IMP	Process
GO:0010628	positive regulation of gene expression	-	ISO	Process
GO:0010629	negative regulation of gene expression	-	ISO	Process
GO:0016458	gene silencing	10615135.	IDA	Process
GO:0016740	transferase activity	-	IEA	Function
GO:0019904	protein domain specific binding	-	ISO	Function
GO:0030331	estrogen receptor binding	-	ISO	Function
GO:0032259	methylation	-	IEA	Process
GO:0032776	DNA methylation on cytosine	1606615.	IMP	Process
GO:0032776	DNA methylation on cytosine	-	ISO	Process
GO:0032991	protein-containing complex	-	ISO	Component
GO:0042127	regulation of cell proliferation	10919675.	IGI	Process
GO:0042493	response to drug	-	ISO	Process
GO:0042826	histone deacetylase binding	-	ISO	Function
GO:0043025	neuronal cell body	-	ISO	Component
GO:0043045	DNA methylation involved in embryo development	1606615.	IMP	Process
GO:0044026	DNA hypermethylation	-	ISO	Process
GO:0045892	negative regulation of transcription, DNA-templated	10888872.	IDA	Process
GO:0045892	negative regulation of transcription, DNA-templated	17245608.	IMP	Process
GO:0046500	S-adenosylmethionine metabolic process	-	ISO	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0051571	positive regulation of histone H3-K4 methylation	-	ISO	Process
GO:0051573	negative regulation of histone H3-K9 methylation	-	ISO	Process
GO:0071230	cellular response to amino acid stimulus	20548288.	IDA	Process
GO:0071560	cellular response to transforming growth factor beta stimulus	-	ISO	Process
GO:0090116	C-5 methylation of cytosine	-	IEA	Process
GO:0090309	positive regulation of methylation-dependent chromatin silencing	-	ISO	Process
GO:1904707	positive regulation of vascular smooth muscle cell proliferation	-	ISO	Process
GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process	-	ISO	Process
GO:1905931	negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching	-	ISO	Process
GO:1990841	promoter-specific chromatin binding	-	ISO	Function