EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Gene Ontology

Description

Ensembl ID: ENSMUSG00000004266 (Gene tree)
Gene ID: 15170
Gene Symbol: Ptpn6
Alias: Hcph|Ptp1C|SHP-1|hcp
Full Name: protein tyrosine phosphatase%2C non-receptor type 6
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 18008
Position: chr6: 124720707-124738714
Accession: 96055
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000172690	-	134	-	ENSMUSP00000134638	45 (aa)	-	G3UZU6
ENSMUST00000004377	-	2308	-	ENSMUSP00000004377	597 (aa)	-	P29351
ENSMUST00000172613	-	421	-	-	- (aa)	-	-
ENSMUST00000173647	-	330	-	ENSMUSP00000133747	67 (aa)	-	G3UXM2
ENSMUST00000173315	-	456	-	ENSMUSP00000134274	101 (aa)	-	G3UYY5
ENSMUST00000172770	-	371	-	-	- (aa)	-	-
ENSMUST00000173228	-	198	-	-	- (aa)	-	-
ENSMUST00000112484	-	2219	-	ENSMUSP00000108103	595 (aa)	-	P29351
ENSMUST00000174787	-	120	-	ENSMUSP00000133429	40 (aa)	-	G3UWU7
ENSMUST00000171549	-	2226	-	ENSMUSP00000129124	597 (aa)	-	P29351
ENSMUST00000174265	-	1743	-	ENSMUSP00000133991	556 (aa)	-	P29351

Gene Model

Click here to download ENSMUSG00000004266's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04520	Adherens junction	KEGG
mmu04630	JAK-STAT signaling pathway	KEGG
mmu04650	Natural killer cell mediated cytotoxicity	KEGG
mmu04660	T cell receptor signaling pathway	KEGG
mmu04662	B cell receptor signaling pathway	KEGG
mmu05140	Leishmaniasis	KEGG
mmu05205	Proteoglycans in cancer	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000004266's network

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001784	phosphotyrosine residue binding	10229828.	IPI	Function
GO:0001784	phosphotyrosine residue binding	-	ISO	Function
GO:0002244	hematopoietic progenitor cell differentiation	24029230.	IMP	Process
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	9254656.	IMP	Process
GO:0004721	phosphoprotein phosphatase activity	-	IEA	Function
GO:0004725	protein tyrosine phosphatase activity	8632004.8943354.9064344.10585470.	IDA	Function
GO:0004725	protein tyrosine phosphatase activity	-	ISO	Function
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	-	ISO	Function
GO:0005515	protein binding	8632004.8943354.9047385.9064344.9867848.9890995.10229823.11551923.12646217.12893283.17954568.18028878.19171907.20526344.21029969.22496641.23001144.23112346.23509253.24360797.25915125.	IPI	Function
GO:0005634	nucleus	-	ISO	Component
GO:0005730	nucleolus	-	ISO	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005737	cytoplasm	8943354.	TAS	Component
GO:0005911	cell-cell junction	23793062.	IDA	Component
GO:0006470	protein dephosphorylation	8632004.9064344.	IDA	Process
GO:0006470	protein dephosphorylation	9064344.	IMP	Process
GO:0006470	protein dephosphorylation	-	ISO	Process
GO:0008283	cell proliferation	-	ISO	Process
GO:0008284	positive regulation of cell proliferation	-	ISO	Process
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	-	ISO	Process
GO:0016311	dephosphorylation	-	IEA	Process
GO:0016787	hydrolase activity	-	IEA	Function
GO:0016791	phosphatase activity	-	IEA	Function
GO:0017124	SH3 domain binding	8632004.	IDA	Function
GO:0018108	peptidyl-tyrosine phosphorylation	-	ISO	Process
GO:0019221	cytokine-mediated signaling pathway	8943354.	TAS	Process
GO:0019901	protein kinase binding	-	ISO	Function
GO:0030154	cell differentiation	-	ISO	Process
GO:0030220	platelet formation	23509158.	IGI	Process
GO:0032715	negative regulation of interleukin-6 production	17954568.	IGI	Process
GO:0032720	negative regulation of tumor necrosis factor production	17954568.	IGI	Process
GO:0032991	protein-containing complex	-	ISO	Component
GO:0033277	abortive mitotic cell cycle	23509158.	IMP	Process
GO:0033630	positive regulation of cell adhesion mediated by integrin	23509158.	IMP	Process
GO:0035335	peptidyl-tyrosine dephosphorylation	-	ISO	Process
GO:0035556	intracellular signal transduction	10229828.	IDA	Process
GO:0035855	megakaryocyte development	23509158.	IMP	Process
GO:0042105	alpha-beta T cell receptor complex	9064344.	IDA	Component
GO:0042130	negative regulation of T cell proliferation	9064344.	IMP	Process
GO:0042169	SH2 domain binding	8632004.	IDA	Function
GO:0042267	natural killer cell mediated cytotoxicity	6971254.	IMP	Process
GO:0043407	negative regulation of MAP kinase activity	9064344.9254656.	IMP	Process
GO:0043409	negative regulation of MAPK cascade	9064344.9254656.	IMP	Process
GO:0045577	regulation of B cell differentiation	9254656.	IMP	Process
GO:0046703	natural killer cell lectin-like receptor binding	-	ISO	Function
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	9254656.	IMP	Process
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	-	ISO	Process
GO:0050839	cell adhesion molecule binding	19948503.	IPI	Function
GO:0050853	B cell receptor signaling pathway	9254656.	IMP	Process
GO:0050859	negative regulation of B cell receptor signaling pathway	23509253.	IGI	Process
GO:0050860	negative regulation of T cell receptor signaling pathway	9064344.	IMP	Process
GO:0051279	regulation of release of sequestered calcium ion into cytosol	23509253.	IGI	Process
GO:0070372	regulation of ERK1 and ERK2 cascade	-	ISO	Process
GO:0070527	platelet aggregation	23509158.	IMP	Process
GO:0140031	phosphorylation-dependent protein binding	-	ISO	Function
GO:2000045	regulation of G1/S transition of mitotic cell cycle	-	ISO	Process