EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000004667 (Gene tree)
Gene ID: 66420
Gene Symbol: Polr2e
Alias: 25kDa|RPB5|XAP4
Full Name: polymerase (RNA) II (DNA directed) polypeptide E
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Minus strand
Length: 3847 bases
Position: chr10:80035949-80039795
Accession: 1913670
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000004786	RNA_pol_Rpb5_N	PF03871.14	1.9e-34	1	1
ENSMUSP00000004786	RNA_pol_Rpb5_C	PF01191.19	1.7e-34	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000131743	-	1238	-	-	- (aa)	-	-
ENSMUST00000152843	-	900	-	-	- (aa)	-	-
ENSMUST00000147507	-	792	-	-	- (aa)	-	-
ENSMUST00000143438	-	2403	-	-	- (aa)	-	-
ENSMUST00000004786	-	1148	-	ENSMUSP00000004786	210 (aa)	-	Q80UW8

Gene Model

Click here to download ENSMUSG00000004667's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03020	RNA polymerase	KEGG
mmu04623	Cytosolic DNA-sensing pathway	KEGG
mmu05016	Huntington disease	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000004667's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000004667	Polr2e	100	98.571	ENSG00000099817	POLR2E	100	98.571	Homo_sapiens
ENSMUSG00000004667	Polr2e	100	95.714	ENSAPOG00000002935	polr2eb	100	95.714	Acanthochromis_polyacanthus
ENSMUSG00000004667	Polr2e	100	99.048	ENSAMEG00000003159	POLR2E	100	99.048	Ailuropoda_melanoleuca
ENSMUSG00000004667	Polr2e	100	83.810	ENSACIG00000024371	polr2eb	100	83.810	Amphilophus_citrinellus
ENSMUSG00000004667	Polr2e	100	95.714	ENSAOCG00000018166	polr2eb	100	95.714	Amphiprion_ocellaris
ENSMUSG00000004667	Polr2e	100	95.714	ENSAPEG00000009000	polr2eb	100	95.714	Amphiprion_percula
ENSMUSG00000004667	Polr2e	100	95.714	ENSATEG00000023760	polr2eb	100	95.714	Anabas_testudineus
ENSMUSG00000004667	Polr2e	100	99.048	ENSANAG00000038488	POLR2E	100	99.048	Aotus_nancymaae
ENSMUSG00000004667	Polr2e	100	96.190	ENSACLG00000005254	polr2eb	100	96.190	Astatotilapia_calliptera
ENSMUSG00000004667	Polr2e	100	96.190	ENSAMXG00000018915	POLR2E	100	96.190	Astyanax_mexicanus
ENSMUSG00000004667	Polr2e	100	99.048	ENSBTAG00000020776	POLR2E	100	99.048	Bos_taurus
ENSMUSG00000004667	Polr2e	99	78.365	WBGene00019246	rpb-5	99	78.365	Caenorhabditis_elegans
ENSMUSG00000004667	Polr2e	67	94.286	ENSCJAG00000007666	-	77	94.286	Callithrix_jacchus
ENSMUSG00000004667	Polr2e	100	95.714	ENSCAFG00000019546	POLR2E	100	95.714	Canis_familiaris
ENSMUSG00000004667	Polr2e	100	99.048	ENSCAFG00020017111	POLR2E	100	99.048	Canis_lupus_dingo
ENSMUSG00000004667	Polr2e	100	99.048	ENSCHIG00000014151	POLR2E	100	99.048	Capra_hircus
ENSMUSG00000004667	Polr2e	100	80.930	ENSTSYG00000026377	POLR2E	100	80.930	Carlito_syrichta
ENSMUSG00000004667	Polr2e	91	98.958	ENSCAPG00000010843	POLR2E	93	98.958	Cavia_aperea
ENSMUSG00000004667	Polr2e	100	99.048	ENSCPOG00000001542	POLR2E	100	99.048	Cavia_porcellus
ENSMUSG00000004667	Polr2e	100	99.048	ENSCCAG00000025658	POLR2E	100	99.048	Cebus_capucinus
ENSMUSG00000004667	Polr2e	100	99.048	ENSCATG00000008926	POLR2E	100	99.048	Cercocebus_atys
ENSMUSG00000004667	Polr2e	98	75.610	ENSCLAG00000009238	-	100	75.610	Chinchilla_lanigera
ENSMUSG00000004667	Polr2e	100	98.571	ENSCLAG00000014874	-	100	98.571	Chinchilla_lanigera
ENSMUSG00000004667	Polr2e	100	99.048	ENSCSAG00000012336	POLR2E	100	99.048	Chlorocebus_sabaeus
ENSMUSG00000004667	Polr2e	100	98.571	ENSCPBG00000009702	POLR2E	100	98.571	Chrysemys_picta_bellii
ENSMUSG00000004667	Polr2e	100	85.714	ENSCING00000024933	-	99	85.714	Ciona_intestinalis
ENSMUSG00000004667	Polr2e	100	99.048	ENSCANG00000025560	POLR2E	100	99.048	Colobus_angolensis_palliatus
ENSMUSG00000004667	Polr2e	100	100.000	ENSCGRG00001022927	Polr2e	100	100.000	Cricetulus_griseus_chok1gshd
ENSMUSG00000004667	Polr2e	100	93.488	ENSCGRG00000016441	Polr2e	100	93.488	Cricetulus_griseus_crigri
ENSMUSG00000004667	Polr2e	100	94.762	ENSCSEG00000007107	polr2eb	92	94.762	Cynoglossus_semilaevis
ENSMUSG00000004667	Polr2e	100	95.714	ENSCVAG00000019940	polr2eb	100	95.714	Cyprinodon_variegatus
ENSMUSG00000004667	Polr2e	100	94.762	ENSDARG00000026183	polr2eb	100	94.762	Danio_rerio
ENSMUSG00000004667	Polr2e	90	98.947	ENSDNOG00000044994	POLR2E	84	98.947	Dasypus_novemcinctus
ENSMUSG00000004667	Polr2e	100	99.048	ENSDORG00000001154	Polr2e	100	99.048	Dipodomys_ordii
ENSMUSG00000004667	Polr2e	99	84.689	FBgn0033571	Rpb5	99	84.689	Drosophila_melanogaster
ENSMUSG00000004667	Polr2e	75	91.083	ENSEBUG00000010159	-	76	91.083	Eptatretus_burgeri
ENSMUSG00000004667	Polr2e	69	92.414	ENSEASG00005021615	POLR2E	67	86.420	Equus_asinus_asinus
ENSMUSG00000004667	Polr2e	91	97.906	ENSECAG00000011124	POLR2E	100	86.667	Equus_caballus
ENSMUSG00000004667	Polr2e	100	94.286	ENSELUG00000005815	POLR2E	100	94.286	Esox_lucius
ENSMUSG00000004667	Polr2e	100	93.333	ENSELUG00000020646	polr2e	100	93.333	Esox_lucius
ENSMUSG00000004667	Polr2e	100	99.524	ENSFCAG00000007318	POLR2E	100	99.524	Felis_catus
ENSMUSG00000004667	Polr2e	91	98.438	ENSFALG00000013986	POLR2E	99	98.438	Ficedula_albicollis
ENSMUSG00000004667	Polr2e	100	99.048	ENSFDAG00000014539	POLR2E	100	99.048	Fukomys_damarensis
ENSMUSG00000004667	Polr2e	100	95.714	ENSFHEG00000022398	polr2eb	100	95.714	Fundulus_heteroclitus
ENSMUSG00000004667	Polr2e	100	94.286	ENSGMOG00000007615	polr2eb	100	94.286	Gadus_morhua
ENSMUSG00000004667	Polr2e	100	98.571	ENSGALG00000002591	POLR2E	100	98.571	Gallus_gallus
ENSMUSG00000004667	Polr2e	100	96.190	ENSGAFG00000005087	polr2eb	100	96.190	Gambusia_affinis
ENSMUSG00000004667	Polr2e	100	94.286	ENSGACG00000013247	polr2eb	100	94.286	Gasterosteus_aculeatus
ENSMUSG00000004667	Polr2e	100	98.571	ENSGAGG00000008356	POLR2E	100	98.571	Gopherus_agassizii
ENSMUSG00000004667	Polr2e	100	99.048	ENSGGOG00000011267	POLR2E	100	99.048	Gorilla_gorilla
ENSMUSG00000004667	Polr2e	68	90.141	ENSHBUG00000011099	polr2eb	100	90.141	Haplochromis_burtoni
ENSMUSG00000004667	Polr2e	100	98.095	ENSHGLG00000013330	POLR2E	100	98.095	Heterocephalus_glaber_female
ENSMUSG00000004667	Polr2e	100	98.095	ENSHGLG00100011014	POLR2E	100	98.095	Heterocephalus_glaber_male
ENSMUSG00000004667	Polr2e	53	91.071	ENSHCOG00000012099	-	88	91.071	Hippocampus_comes
ENSMUSG00000004667	Polr2e	100	94.286	ENSHCOG00000000906	polr2eb	100	94.286	Hippocampus_comes
ENSMUSG00000004667	Polr2e	100	95.714	ENSIPUG00000019801	polr2e	100	95.714	Ictalurus_punctatus
ENSMUSG00000004667	Polr2e	100	99.048	ENSSTOG00000002853	POLR2E	100	99.048	Ictidomys_tridecemlineatus
ENSMUSG00000004667	Polr2e	100	80.476	ENSJJAG00000003145	-	100	80.476	Jaculus_jaculus
ENSMUSG00000004667	Polr2e	100	100.000	ENSJJAG00000016595	-	100	100.000	Jaculus_jaculus
ENSMUSG00000004667	Polr2e	77	81.988	ENSJJAG00000015812	-	100	81.988	Jaculus_jaculus
ENSMUSG00000004667	Polr2e	100	95.714	ENSKMAG00000005954	polr2eb	100	95.714	Kryptolebias_marmoratus
ENSMUSG00000004667	Polr2e	100	95.714	ENSLBEG00000024802	polr2eb	100	95.714	Labrus_bergylta
ENSMUSG00000004667	Polr2e	100	95.714	ENSLACG00000013686	POLR2E	100	95.714	Latimeria_chalumnae
ENSMUSG00000004667	Polr2e	77	96.296	ENSLOCG00000004599	POLR2E	100	96.296	Lepisosteus_oculatus
ENSMUSG00000004667	Polr2e	100	79.245	ENSLAFG00000025587	POLR2E	100	79.245	Loxodonta_africana
ENSMUSG00000004667	Polr2e	100	99.048	ENSMFAG00000002884	POLR2E	100	99.048	Macaca_fascicularis
ENSMUSG00000004667	Polr2e	100	99.048	ENSMMUG00000013927	POLR2E	100	99.048	Macaca_mulatta
ENSMUSG00000004667	Polr2e	100	65.877	ENSMNEG00000033452	-	100	65.877	Macaca_nemestrina
ENSMUSG00000004667	Polr2e	100	99.048	ENSMNEG00000034046	-	100	99.048	Macaca_nemestrina
ENSMUSG00000004667	Polr2e	92	80.311	ENSMLEG00000012405	POLR2E	94	80.311	Mandrillus_leucophaeus
ENSMUSG00000004667	Polr2e	100	95.714	ENSMAMG00000018703	polr2eb	100	95.714	Mastacembelus_armatus
ENSMUSG00000004667	Polr2e	90	95.789	ENSMZEG00005010796	polr2eb	96	95.789	Maylandia_zebra
ENSMUSG00000004667	Polr2e	100	97.156	ENSMGAG00000003769	POLR2E	100	97.156	Meleagris_gallopavo
ENSMUSG00000004667	Polr2e	92	99.482	ENSMAUG00000010125	-	100	100.000	Mesocricetus_auratus
ENSMUSG00000004667	Polr2e	100	68.571	ENSMAUG00000011003	-	100	68.571	Mesocricetus_auratus
ENSMUSG00000004667	Polr2e	100	99.048	ENSMICG00000013063	POLR2E	100	99.048	Microcebus_murinus
ENSMUSG00000004667	Polr2e	100	100.000	ENSMOCG00000013414	Polr2e	100	100.000	Microtus_ochrogaster
ENSMUSG00000004667	Polr2e	91	85.864	ENSMMOG00000001167	polr2eb	88	85.864	Mola_mola
ENSMUSG00000004667	Polr2e	100	81.429	ENSMMOG00000001161	polr2eb	100	81.429	Mola_mola
ENSMUSG00000004667	Polr2e	100	98.571	ENSMODG00000005494	POLR2E	100	98.571	Monodelphis_domestica
ENSMUSG00000004667	Polr2e	100	96.190	ENSMALG00000021888	polr2eb	100	96.190	Monopterus_albus
ENSMUSG00000004667	Polr2e	100	100.000	MGP_CAROLIEiJ_G0015561	Polr2e	100	100.000	Mus_caroli
ENSMUSG00000004667	Polr2e	100	100.000	MGP_PahariEiJ_G0030974	Polr2e	100	100.000	Mus_pahari
ENSMUSG00000004667	Polr2e	100	100.000	MGP_SPRETEiJ_G0016379	Polr2e	100	100.000	Mus_spretus
ENSMUSG00000004667	Polr2e	100	99.048	ENSMPUG00000008953	POLR2E	100	99.048	Mustela_putorius_furo
ENSMUSG00000004667	Polr2e	100	99.048	ENSMLUG00000013193	POLR2E	100	99.048	Myotis_lucifugus
ENSMUSG00000004667	Polr2e	66	93.478	ENSMLUG00000006376	-	100	82.099	Myotis_lucifugus
ENSMUSG00000004667	Polr2e	85	75.419	ENSNGAG00000017344	-	96	75.419	Nannospalax_galili
ENSMUSG00000004667	Polr2e	100	100.000	ENSNGAG00000001147	Polr2e	100	100.000	Nannospalax_galili
ENSMUSG00000004667	Polr2e	100	83.810	ENSNBRG00000022772	polr2eb	100	83.810	Neolamprologus_brichardi
ENSMUSG00000004667	Polr2e	100	76.190	ENSNLEG00000031364	-	100	76.190	Nomascus_leucogenys
ENSMUSG00000004667	Polr2e	100	95.261	ENSNLEG00000001207	-	100	95.261	Nomascus_leucogenys
ENSMUSG00000004667	Polr2e	100	87.619	ENSOPRG00000008331	POLR2E	100	87.619	Ochotona_princeps
ENSMUSG00000004667	Polr2e	100	72.381	ENSODEG00000011490	-	100	72.381	Octodon_degus
ENSMUSG00000004667	Polr2e	89	87.634	ENSODEG00000007985	-	100	87.634	Octodon_degus
ENSMUSG00000004667	Polr2e	100	99.048	ENSODEG00000013230	-	100	99.048	Octodon_degus
ENSMUSG00000004667	Polr2e	100	95.714	ENSONIG00000002519	polr2eb	100	95.714	Oreochromis_niloticus
ENSMUSG00000004667	Polr2e	100	96.190	ENSORLG00000015346	polr2eb	100	96.190	Oryzias_latipes
ENSMUSG00000004667	Polr2e	100	96.190	ENSORLG00020020700	polr2e	100	96.190	Oryzias_latipes_hni
ENSMUSG00000004667	Polr2e	100	96.190	ENSORLG00015016842	polr2e	100	96.190	Oryzias_latipes_hsok
ENSMUSG00000004667	Polr2e	100	95.714	ENSOMEG00000002709	polr2eb	100	95.714	Oryzias_melastigma
ENSMUSG00000004667	Polr2e	100	99.048	ENSOGAG00000012311	POLR2E	100	99.048	Otolemur_garnettii
ENSMUSG00000004667	Polr2e	100	99.048	ENSOARG00000010994	POLR2E	100	99.048	Ovis_aries
ENSMUSG00000004667	Polr2e	91	98.953	ENSPPAG00000003145	POLR2E	100	98.953	Pan_paniscus
ENSMUSG00000004667	Polr2e	100	99.524	ENSPPRG00000000777	POLR2E	100	99.524	Panthera_pardus
ENSMUSG00000004667	Polr2e	91	77.083	ENSPTIG00000012237	POLR2E	98	94.737	Panthera_tigris_altaica
ENSMUSG00000004667	Polr2e	100	99.048	ENSPTRG00000010183	POLR2E	100	99.048	Pan_troglodytes
ENSMUSG00000004667	Polr2e	100	99.048	ENSPANG00000018011	POLR2E	100	99.048	Papio_anubis
ENSMUSG00000004667	Polr2e	100	94.762	ENSPKIG00000024123	POLR2E	100	94.762	Paramormyrops_kingsleyae
ENSMUSG00000004667	Polr2e	100	94.762	ENSPKIG00000009607	POLR2E	100	94.762	Paramormyrops_kingsleyae
ENSMUSG00000004667	Polr2e	98	94.634	ENSPSIG00000002870	POLR2E	99	94.634	Pelodiscus_sinensis
ENSMUSG00000004667	Polr2e	100	83.333	ENSPMGG00000014354	polr2eb	100	83.333	Periophthalmus_magnuspinnatus
ENSMUSG00000004667	Polr2e	100	100.000	ENSPEMG00000023261	Polr2e	100	100.000	Peromyscus_maniculatus_bairdii
ENSMUSG00000004667	Polr2e	90	98.413	ENSPCIG00000007312	POLR2E	75	98.413	Phascolarctos_cinereus
ENSMUSG00000004667	Polr2e	100	96.190	ENSPFOG00000005734	polr2eb	100	96.190	Poecilia_formosa
ENSMUSG00000004667	Polr2e	100	96.190	ENSPLAG00000014496	polr2eb	100	96.190	Poecilia_latipinna
ENSMUSG00000004667	Polr2e	100	96.190	ENSPMEG00000008053	polr2eb	100	96.190	Poecilia_mexicana
ENSMUSG00000004667	Polr2e	100	96.190	ENSPREG00000006489	polr2eb	100	96.190	Poecilia_reticulata
ENSMUSG00000004667	Polr2e	100	91.469	ENSPPYG00000009305	POLR2E	100	91.469	Pongo_abelii
ENSMUSG00000004667	Polr2e	53	98.198	ENSPCAG00000016605	POLR2E	100	98.198	Procavia_capensis
ENSMUSG00000004667	Polr2e	100	99.048	ENSPCOG00000014491	POLR2E	100	99.048	Propithecus_coquereli
ENSMUSG00000004667	Polr2e	65	100.000	ENSPVAG00000007718	-	55	100.000	Pteropus_vampyrus
ENSMUSG00000004667	Polr2e	90	95.789	ENSPNYG00000019797	polr2eb	96	95.789	Pundamilia_nyererei
ENSMUSG00000004667	Polr2e	100	95.714	ENSPNAG00000026263	POLR2E	100	95.714	Pygocentrus_nattereri
ENSMUSG00000004667	Polr2e	100	100.000	ENSRNOG00000013545	Polr2e	100	100.000	Rattus_norvegicus
ENSMUSG00000004667	Polr2e	100	72.986	ENSRBIG00000027259	-	100	72.986	Rhinopithecus_bieti
ENSMUSG00000004667	Polr2e	100	99.048	ENSRBIG00000028726	-	100	99.048	Rhinopithecus_bieti
ENSMUSG00000004667	Polr2e	100	99.048	ENSRROG00000043763	POLR2E	100	99.048	Rhinopithecus_roxellana
ENSMUSG00000004667	Polr2e	99	44.037	YBR154C	RPB5	98	44.037	Saccharomyces_cerevisiae
ENSMUSG00000004667	Polr2e	100	99.048	ENSSBOG00000027241	POLR2E	100	99.048	Saimiri_boliviensis_boliviensis
ENSMUSG00000004667	Polr2e	100	98.571	ENSSHAG00000010690	POLR2E	100	98.571	Sarcophilus_harrisii
ENSMUSG00000004667	Polr2e	100	95.714	ENSSFOG00015006073	polr2e	100	95.714	Scleropages_formosus
ENSMUSG00000004667	Polr2e	100	95.714	ENSSMAG00000012782	polr2eb	100	95.714	Scophthalmus_maximus
ENSMUSG00000004667	Polr2e	100	95.714	ENSSDUG00000003352	polr2eb	100	95.714	Seriola_dumerili
ENSMUSG00000004667	Polr2e	100	95.714	ENSSLDG00000004965	polr2eb	100	95.714	Seriola_lalandi_dorsalis
ENSMUSG00000004667	Polr2e	100	97.143	ENSSPUG00000006114	POLR2E	100	97.143	Sphenodon_punctatus
ENSMUSG00000004667	Polr2e	100	95.714	ENSSPAG00000017556	polr2eb	100	95.714	Stegastes_partitus
ENSMUSG00000004667	Polr2e	100	99.048	ENSSSCG00000021472	POLR2E	100	99.048	Sus_scrofa
ENSMUSG00000004667	Polr2e	66	90.000	ENSTGUG00000000922	POLR2E	99	90.000	Taeniopygia_guttata
ENSMUSG00000004667	Polr2e	96	91.045	ENSTRUG00000018238	polr2eb	100	83.333	Takifugu_rubripes
ENSMUSG00000004667	Polr2e	100	95.714	ENSTNIG00000013187	polr2eb	100	95.714	Tetraodon_nigroviridis
ENSMUSG00000004667	Polr2e	100	98.571	ENSTTRG00000001484	POLR2E	100	98.571	Tursiops_truncatus
ENSMUSG00000004667	Polr2e	92	95.876	ENSUAMG00000009166	POLR2E	100	86.190	Ursus_americanus
ENSMUSG00000004667	Polr2e	100	99.048	ENSVVUG00000022818	POLR2E	54	99.048	Vulpes_vulpes
ENSMUSG00000004667	Polr2e	100	97.619	ENSXETG00000003291	polr2e	100	97.619	Xenopus_tropicalis
ENSMUSG00000004667	Polr2e	100	83.810	ENSXCOG00000009197	polr2eb	100	83.810	Xiphophorus_couchianus
ENSMUSG00000004667	Polr2e	100	96.190	ENSXMAG00000026495	polr2eb	100	96.190	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001054	RNA polymerase I activity	21873635.	IBA	Function
GO:0001055	RNA polymerase II activity	21873635.	IBA	Function
GO:0001056	RNA polymerase III activity	21873635.	IBA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	21873635.	IBA	Function
GO:0005634	nucleus	-	ISO	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005665	RNA polymerase II, core complex	21873635.	IBA	Component
GO:0005665	RNA polymerase II, core complex	-	ISO	Component
GO:0005666	RNA polymerase III complex	21873635.	IBA	Component
GO:0005736	RNA polymerase I complex	21873635.	IBA	Component
GO:0006351	transcription, DNA-templated	-	IEA	Process
GO:0006366	transcription by RNA polymerase II	-	ISO	Process