EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000005370 (Gene tree)
Gene ID: 17688
Gene Symbol: Msh6
Alias: GTBP|Gtmbp|Msh6
Full Name: mutS homolog 6
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 15831
Position: chr17: 87975062-87990892
Accession: 1343961
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000234936	-	479	-	-	- (aa)	-	-
ENSMUST00000234756	-	578	-	ENSMUSP00000157173	167 (aa)	-	-
ENSMUST00000005503	-	4251	-	ENSMUSP00000005503	1358 (aa)	-	P54276

Gene Model

Click here to download ENSMUSG00000005370's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu01524	Platinum drug resistance	KEGG
mmu03430	Mismatch repair	KEGG
mmu05200	Pathways in cancer	KEGG
mmu05210	Colorectal cancer	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000005370's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000005370	Msh6	80	44.203	FBgn0036486	Msh6	89	44.283	Drosophila_melanogaster
ENSMUSG00000005370	Msh6	100	85.337	ENSG00000116062	MSH6	100	96.078	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0000287	magnesium ion binding	-	ISO	Function
GO:0000400	four-way junction DNA binding	21873635.	IBA	Function
GO:0000400	four-way junction DNA binding	-	ISO	Function
GO:0000710	meiotic mismatch repair	21873635.	IBA	Process
GO:0000790	nuclear chromatin	16618598.	IDA	Component
GO:0003677	DNA binding	10545954.	IGI	Function
GO:0003677	DNA binding	10545954.	IMP	Function
GO:0003682	chromatin binding	16618598.	IDA	Function
GO:0003684	damaged DNA binding	21873635.	IBA	Function
GO:0003684	damaged DNA binding	10545954.	IGI	Function
GO:0003684	damaged DNA binding	10545954.	IMP	Function
GO:0003690	double-stranded DNA binding	-	ISO	Function
GO:0005524	ATP binding	21873635.	IBA	Function
GO:0005524	ATP binding	-	ISO	Function
GO:0005634	nucleus	-	ISO	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005694	chromosome	-	IEA	Component
GO:0005794	Golgi apparatus	-	ISO	Component
GO:0005829	cytosol	-	ISO	Component
GO:0006281	DNA repair	-	ISO	Process
GO:0006290	pyrimidine dimer repair	21873635.	IBA	Process
GO:0006298	mismatch repair	21873635.	IBA	Process
GO:0006298	mismatch repair	11691815.16728433.	IGI	Process
GO:0006298	mismatch repair	9390556.12370835.15324697.16728433.23071719.	IMP	Process
GO:0006298	mismatch repair	23603115.	ISO	Process
GO:0006974	cellular response to DNA damage stimulus	-	IEA	Process
GO:0007095	mitotic G2 DNA damage checkpoint	21873635.	IBA	Process
GO:0008094	DNA-dependent ATPase activity	21873635.	IBA	Function
GO:0008340	determination of adult lifespan	9390556.10545954.	IMP	Process
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	21873635.	IBA	Process
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	15324697.	IMP	Process
GO:0009411	response to UV	21873635.	IBA	Process
GO:0009411	response to UV	14632208.	IMP	Process
GO:0016446	somatic hypermutation of immunoglobulin genes	10662804.15238604.16618598.17015724.	IMP	Process
GO:0016447	somatic recombination of immunoglobulin gene segments	15238604.	IMP	Process
GO:0016887	ATPase activity	-	ISO	Function
GO:0019899	enzyme binding	-	ISO	Function
GO:0030983	mismatched DNA binding	-	ISO	Function
GO:0030983	mismatched DNA binding	-	ISO	Function
GO:0032137	guanine/thymine mispair binding	21873635.	IBA	Function
GO:0032137	guanine/thymine mispair binding	15324697.	IDA	Function
GO:0032137	guanine/thymine mispair binding	16713580.	IDA	Function
GO:0032137	guanine/thymine mispair binding	-	ISO	Function
GO:0032142	single guanine insertion binding	-	ISO	Function
GO:0032143	single thymine insertion binding	21873635.	IBA	Function
GO:0032143	single thymine insertion binding	-	ISO	Function
GO:0032300	mismatch repair complex	21873635.	IBA	Component
GO:0032301	MutSalpha complex	21873635.	IBA	Component
GO:0032301	MutSalpha complex	16713580.	IDA	Component
GO:0032301	MutSalpha complex	-	ISO	Component
GO:0032357	oxidized purine DNA binding	-	ISO	Function
GO:0032405	MutLalpha complex binding	21873635.	IBA	Function
GO:0032405	MutLalpha complex binding	-	ISO	Function
GO:0032876	negative regulation of DNA endoreduplication	21873635.	IBA	Process
GO:0035064	methylated histone binding	21873635.	IBA	Function
GO:0035064	methylated histone binding	-	ISO	Function
GO:0036297	interstrand cross-link repair	21873635.	IBA	Process
GO:0043111	replication fork arrest	21873635.	IBA	Process
GO:0043231	intracellular membrane-bounded organelle	-	ISO	Component
GO:0043531	ADP binding	21873635.	IBA	Function
GO:0043531	ADP binding	-	ISO	Function
GO:0043570	maintenance of DNA repeat elements	21873635.	IBA	Process
GO:0045190	isotype switching	17015724.	IGI	Process
GO:0045190	isotype switching	16618598.	IMP	Process
GO:0045910	negative regulation of DNA recombination	21873635.	IBA	Process
GO:0045910	negative regulation of DNA recombination	10545954.	IMP	Process
GO:0045910	negative regulation of DNA recombination	-	ISO	Process
GO:0051096	positive regulation of helicase activity	21873635.	IBA	Process
GO:0051096	positive regulation of helicase activity	-	ISO	Process
GO:0097193	intrinsic apoptotic signaling pathway	14632208.	IMP	Process