EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000006494 (Gene tree)
Gene ID: 228026
Gene Symbol: Pdk1
Alias: D530020C15Rik
Full Name: pyruvate dehydrogenase kinase%2C isoenzyme 1
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 30635
Position: chr2: 71873224-71903858
Accession: 1926119
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000152696	-	795	-	-	- (aa)	-	-
ENSMUST00000129887	-	680	-	-	- (aa)	-	-
ENSMUST00000006669	-	5185	XM_011239444	ENSMUSP00000006669	434 (aa)	XP_011237746	Q8BFP9
ENSMUST00000151358	-	777	-	-	- (aa)	-	-
ENSMUST00000148249	-	2596	-	-	- (aa)	-	-
ENSMUST00000134362	-	1060	-	-	- (aa)	-	-
ENSMUST00000156036	-	2972	-	-	- (aa)	-	-
ENSMUST00000129427	-	327	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000006494's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04066	HIF-1 signaling pathway	KEGG
mmu04360	Axon guidance	KEGG
mmu05230	Central carbon metabolism in cancer	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000006494's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000006494	Pdk1	89	56.266	FBgn0017558	Pdk	91	57.256	Drosophila_melanogaster
ENSMUSG00000006494	Pdk1	90	69.211	ENSMUSG00000035232	Pdk3	95	69.211	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0004672	protein kinase activity	-	ISO	Function
GO:0004674	protein serine/threonine kinase activity	-	ISO	Function
GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity	-	ISO	Function
GO:0005524	ATP binding	-	ISO	Function
GO:0005634	nucleus	-	ISO	Component
GO:0005730	nucleolus	-	ISO	Component
GO:0005739	mitochondrion	14651853.18614015.	HDA	Component
GO:0005739	mitochondrion	-	ISO	Component
GO:0005886	plasma membrane	14749367.	ISA	Component
GO:0005967	mitochondrial pyruvate dehydrogenase complex	22195962.	IDA	Component
GO:0005975	carbohydrate metabolic process	-	IEA	Process
GO:0006006	glucose metabolic process	-	IEA	Process
GO:0006468	protein phosphorylation	-	ISO	Process
GO:0007166	cell surface receptor signaling pathway	-	ISO	Process
GO:0008283	cell proliferation	-	ISO	Process
GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	-	ISO	Process
GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate	22195962.	IMP	Process
GO:0010906	regulation of glucose metabolic process	-	ISO	Process
GO:0016301	kinase activity	-	IEA	Function
GO:0016310	phosphorylation	-	IEA	Process
GO:0016740	transferase activity	-	IEA	Function
GO:0018105	peptidyl-serine phosphorylation	-	ISO	Process
GO:0035556	intracellular signal transduction	14749367.	ISA	Process
GO:0042803	protein homodimerization activity	-	ISO	Function
GO:0044877	protein-containing complex binding	-	ISO	Function
GO:0045254	pyruvate dehydrogenase complex	-	ISO	Component
GO:0046982	protein heterodimerization activity	-	ISO	Function
GO:0097411	hypoxia-inducible factor-1alpha signaling pathway	-	ISO	Process