EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000015656 (Gene tree)
Gene ID: 15481
Gene Symbol: Hspa8
Alias: 2410008N15Rik|Hsc70|Hsc71|Hsc73|Hsp73
Full Name: heat shock protein 8
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 9104
Position: chr9: 40800984-40810087
Accession: 105384
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
25993413	Label-Free Protein RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression	IC & MEF	2015	Boucas J	DOI: 10.1371/journal.pone.0125745
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000117557	-	2019	-	ENSMUSP00000113722	627 (aa)	-	Q504P4
ENSMUST00000117870	-	598	-	-	- (aa)	-	-
ENSMUST00000215526	-	357	-	-	- (aa)	-	-
ENSMUST00000153847	-	727	-	-	- (aa)	-	-
ENSMUST00000138895	-	920	-	-	- (aa)	-	-
ENSMUST00000127699	-	456	-	-	- (aa)	-	-
ENSMUST00000133964	-	514	-	ENSMUSP00000117285	116 (aa)	-	D3Z5E2
ENSMUST00000149936	-	3158	-	-	- (aa)	-	-
ENSMUST00000140984	-	1152	-	-	- (aa)	-	-
ENSMUST00000015800	-	2394	-	ENSMUSP00000015800	646 (aa)	-	P63017

Gene Model

Click here to download ENSMUSG00000015656's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03040	Spliceosome	KEGG
mmu04010	MAPK signaling pathway	KEGG
mmu04141	Protein processing in endoplasmic reticulum	KEGG
mmu04144	Endocytosis	KEGG
mmu04213	Longevity regulating pathway - multiple species	KEGG
mmu04612	Antigen processing and presentation	KEGG
mmu04915	Estrogen signaling pathway	KEGG
mmu05134	Legionellosis	KEGG
mmu05145	Toxoplasmosis	KEGG
mmu05162	Measles	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000015656's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000015656	Hspa8	100	100.000	ENSG00000109971	HSPA8	100	100.000	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000151	ubiquitin ligase complex	-	ISO	Component
GO:0000166	nucleotide binding	-	IEA	Function
GO:0000974	Prp19 complex	-	ISO	Component
GO:0001664	G protein-coupled receptor binding	-	ISO	Function
GO:0001786	phosphatidylserine binding	21238931.	IDA	Function
GO:0001916	positive regulation of T cell mediated cytotoxicity	-	ISO	Process
GO:0001917	photoreceptor inner segment	-	ISO	Component
GO:0003723	RNA binding	-	ISO	Function
GO:0005102	signaling receptor binding	-	ISO	Function
GO:0005515	protein binding	12588994.14644449.18346207.20060297.20111006.23055941.25961502.26581985.	IPI	Function
GO:0005524	ATP binding	21873635.	IBA	Function
GO:0005524	ATP binding	-	ISO	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005681	spliceosomal complex	-	IEA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	26581985.	IDA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005764	lysosome	21873635.	IBA	Component
GO:0005764	lysosome	-	ISO	Component
GO:0005765	lysosomal membrane	-	ISO	Component
GO:0005770	late endosome	21238931.	IDA	Component
GO:0005776	autophagosome	21873635.	IBA	Component
GO:0005776	autophagosome	-	ISO	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	16906134.	IDA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005874	microtubule	-	ISO	Component
GO:0005882	intermediate filament	-	ISO	Component
GO:0005886	plasma membrane	21873635.	IBA	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0006457	protein folding	12588994.	IDA	Process
GO:0006606	protein import into nucleus	-	ISO	Process
GO:0006986	response to unfolded protein	21873635.	IBA	Process
GO:0008021	synaptic vesicle	-	ISO	Component
GO:0008088	axo-dendritic transport	21873635.	IBA	Process
GO:0008134	transcription factor binding	-	ISO	Function
GO:0008380	RNA splicing	-	IEA	Process
GO:0009986	cell surface	-	ISO	Component
GO:0010628	positive regulation of gene expression	-	ISO	Process
GO:0010667	negative regulation of cardiac muscle cell apoptotic process	-	ISO	Process
GO:0014069	postsynaptic density	-	ISO	Component
GO:0016020	membrane	-	IEA	Component
GO:0016192	vesicle-mediated transport	21873635.	IBA	Process
GO:0016887	ATPase activity	21873635.	IBA	Function
GO:0016887	ATPase activity	-	ISO	Function
GO:0019899	enzyme binding	-	ISO	Function
GO:0030424	axon	21873635.	IBA	Component
GO:0030424	axon	-	ISO	Component
GO:0030425	dendrite	21873635.	IBA	Component
GO:0030425	dendrite	-	ISO	Component
GO:0030674	protein binding, bridging	-	ISO	Function
GO:0031072	heat shock protein binding	21873635.	IBA	Function
GO:0031072	heat shock protein binding	-	ISO	Function
GO:0031625	ubiquitin protein ligase binding	-	ISO	Function
GO:0031647	regulation of protein stability	-	ISO	Process
GO:0031686	A1 adenosine receptor binding	-	ISO	Function
GO:0032279	asymmetric synapse	-	ISO	Component
GO:0032991	protein-containing complex	-	ISO	Component
GO:0034605	cellular response to heat	21873635.	IBA	Process
GO:0034620	cellular response to unfolded protein	21873635.	IBA	Process
GO:0042026	protein refolding	21873635.	IBA	Process
GO:0042026	protein refolding	-	ISO	Process
GO:0042277	peptide binding	-	ISO	Function
GO:0042623	ATPase activity, coupled	21873635.	IBA	Function
GO:0042623	ATPase activity, coupled	12588994.	IDA	Function
GO:0042623	ATPase activity, coupled	-	ISO	Function
GO:0043005	neuron projection	-	ISO	Component
GO:0043025	neuronal cell body	-	ISO	Component
GO:0043085	positive regulation of catalytic activity	-	ISO	Process
GO:0043195	terminal bouton	21873635.	IBA	Component
GO:0043195	terminal bouton	-	ISO	Component
GO:0043197	dendritic spine	-	ISO	Component
GO:0043198	dendritic shaft	-	ISO	Component
GO:0043204	perikaryon	-	ISO	Component
GO:0043209	myelin sheath	17634366.	HDA	Component
GO:0043531	ADP binding	-	ISO	Function
GO:0043624	cellular protein complex disassembly	-	ISO	Process
GO:0044183	protein binding involved in protein folding	21873635.	IBA	Function
GO:0044309	neuron spine	-	ISO	Component
GO:0044788	modulation by host of viral process	26581985.	IMP	Process
GO:0044829	positive regulation by host of viral genome replication	26581985.	IMP	Process
GO:0045121	membrane raft	-	ISO	Component
GO:0045862	positive regulation of proteolysis	-	ISO	Process
GO:0045892	negative regulation of transcription, DNA-templated	-	ISO	Process
GO:0046034	ATP metabolic process	-	ISO	Process
GO:0046777	protein autophosphorylation	-	ISO	Process
GO:0048026	positive regulation of mRNA splicing, via spliceosome	23636947.	IMP	Process
GO:0048471	perinuclear region of cytoplasm	14627652.	IDA	Component
GO:0048471	perinuclear region of cytoplasm	-	ISO	Component
GO:0050766	positive regulation of phagocytosis	-	ISO	Process
GO:0051082	unfolded protein binding	21873635.	IBA	Function
GO:0051082	unfolded protein binding	12588994.	IPI	Function
GO:0051082	unfolded protein binding	-	ISO	Function
GO:0051085	chaperone cofactor-dependent protein refolding	21873635.	IBA	Process
GO:0051085	chaperone cofactor-dependent protein refolding	14644449.	IGI	Process
GO:0051087	chaperone binding	-	ISO	Function
GO:0051726	regulation of cell cycle	12588994.	IDA	Process
GO:0051787	misfolded protein binding	21873635.	IBA	Function
GO:0055131	C3HC4-type RING finger domain binding	-	ISO	Function
GO:0061077	chaperone-mediated protein folding	21151134.	EXP	Process
GO:0061077	chaperone-mediated protein folding	21151134.	IDA	Process
GO:0061077	chaperone-mediated protein folding	-	ISO	Process
GO:0061635	regulation of protein complex stability	-	ISO	Process
GO:0061684	chaperone-mediated autophagy	-	ISO	Process
GO:0061738	late endosomal microautophagy	21873635.	IBA	Process
GO:0061738	late endosomal microautophagy	21238931.	IMP	Process
GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	21873635.	IBA	Process
GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	-	ISO	Process
GO:0061741	chaperone-mediated protein transport involved in chaperone-mediated autophagy	21873635.	IBA	Process
GO:0061741	chaperone-mediated protein transport involved in chaperone-mediated autophagy	-	ISO	Process
GO:0070062	extracellular exosome	19724054.	IDA	Component
GO:0070062	extracellular exosome	-	ISO	Component
GO:0072318	clathrin coat disassembly	20160091.	IGI	Process
GO:0072318	clathrin coat disassembly	-	ISO	Process
GO:0097214	positive regulation of lysosomal membrane permeability	-	ISO	Process
GO:0098684	photoreceptor ribbon synapse	24616664.	IDA	Component
GO:0098690	glycinergic synapse	21209184.	IDA	Component
GO:0098690	glycinergic synapse	-	ISO	Component
GO:0098793	presynapse	21151134.	EXP	Component
GO:0098793	presynapse	21151134.24616664.	IDA	Component
GO:0098793	presynapse	-	ISO	Component
GO:0098794	postsynapse	-	ISO	Component
GO:0098880	maintenance of postsynaptic specialization structure	-	ISO	Process
GO:0098978	glutamatergic synapse	28234934.	EXP	Component
GO:0098978	glutamatergic synapse	21209184.28234934.	IDA	Component
GO:0098978	glutamatergic synapse	-	ISO	Component
GO:0099175	regulation of postsynapse organization	28234934.	EXP	Process
GO:0099175	regulation of postsynapse organization	28234934.	IDA	Process
GO:0099523	presynaptic cytosol	21873635.	IBA	Component
GO:0099523	presynaptic cytosol	-	ISO	Component
GO:0099524	postsynaptic cytosol	21873635.	IBA	Component
GO:0099524	postsynaptic cytosol	-	ISO	Component
GO:0099634	postsynaptic specialization membrane	21209184.	IDA	Component
GO:0101031	chaperone complex	-	ISO	Component
GO:1902904	negative regulation of supramolecular fiber organization	-	ISO	Process
GO:1904592	positive regulation of protein refolding	-	ISO	Process
GO:1904593	prostaglandin binding	-	ISO	Function
GO:1904764	chaperone-mediated autophagy translocation complex disassembly	21873635.	IBA	Process
GO:1904764	chaperone-mediated autophagy translocation complex disassembly	-	ISO	Process
GO:1990124	messenger ribonucleoprotein complex	-	ISO	Component
GO:1990832	slow axonal transport	21873635.	IBA	Process
GO:1990833	clathrin-uncoating ATPase activity	21873635.	IBA	Function
GO:1990833	clathrin-uncoating ATPase activity	-	ISO	Function
GO:1990836	lysosomal matrix	-	ISO	Component
GO:1990904	ribonucleoprotein complex	-	ISO	Component