EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000015837 (Gene tree)
Gene ID: 18412
Gene Symbol: Sqstm1
Alias: A170|OSF-6|Osi|STAP|p62
Full Name: sequestosome 1
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 11462
Position: chr11: 50199366-50210827
Accession: 107931
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000154805	-	585	-	-	- (aa)	-	-
ENSMUST00000015981	-	2673	-	ENSMUSP00000015981	404 (aa)	-	Q64337
ENSMUST00000136936	-	953	-	ENSMUSP00000120442	109 (aa)	-	F6VD69
ENSMUST00000102774	-	2037	-	ENSMUSP00000099835	442 (aa)	-	Q64337
ENSMUST00000143379	-	1266	-	ENSMUSP00000118662	382 (aa)	-	D3YZJ1
ENSMUST00000147846	-	457	-	-	- (aa)	-	-
ENSMUST00000131214	-	582	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000015837's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04137	Mitophagy - animal	KEGG
mmu04217	Necroptosis	KEGG
mmu04218	Cellular senescence	KEGG
mmu04380	Osteoclast differentiation	KEGG
mmu05418	Fluid shear stress and atherosclerosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000015837's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000015837	Sqstm1	100	89.819	ENSG00000161011	SQSTM1	100	92.143	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	24035364.	IMP	Process
GO:0000407	phagophore assembly site	21220506.	IDA	Component
GO:0000423	mitophagy	21873635.	IBA	Process
GO:0000423	mitophagy	-	ISO	Process
GO:0000932	P-body	-	ISO	Component
GO:0001934	positive regulation of protein phosphorylation	-	ISO	Process
GO:0002376	immune system process	-	IEA	Process
GO:0003712	transcription coregulator activity	10458914.	TAS	Function
GO:0005080	protein kinase C binding	21873635.	IBA	Function
GO:0005080	protein kinase C binding	-	ISO	Function
GO:0005515	protein binding	15102471.16252010.17389358.18083104.19250911.20173742.22792322.27728806.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005739	mitochondrion	-	ISO	Component
GO:0005764	lysosome	-	IEA	Component
GO:0005768	endosome	-	IEA	Component
GO:0005776	autophagosome	21873635.	IBA	Component
GO:0005776	autophagosome	24713655.	IDA	Component
GO:0005776	autophagosome	24954904.	ISO	Component
GO:0005783	endoplasmic reticulum	-	IEA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0006914	autophagy	-	ISO	Process
GO:0006915	apoptotic process	-	IEA	Process
GO:0007005	mitochondrion organization	21873635.	IBA	Process
GO:0007032	endosome organization	21873635.	IBA	Process
GO:0007032	endosome organization	-	ISO	Process
GO:0008270	zinc ion binding	-	IEA	Function
GO:0016234	inclusion body	-	ISO	Component
GO:0016235	aggresome	21873635.	IBA	Component
GO:0016235	aggresome	22792322.	IDA	Component
GO:0016236	macroautophagy	-	ISO	Process
GO:0016605	PML body	-	ISO	Component
GO:0019899	enzyme binding	-	ISO	Function
GO:0019901	protein kinase binding	-	ISO	Function
GO:0030154	cell differentiation	-	IEA	Process
GO:0031410	cytoplasmic vesicle	-	IEA	Component
GO:0031625	ubiquitin protein ligase binding	-	ISO	Function
GO:0035255	ionotropic glutamate receptor binding	19004011.	IPI	Function
GO:0035973	aggrephagy	21873635.	IBA	Process
GO:0035973	aggrephagy	-	ISO	Process
GO:0042169	SH2 domain binding	-	ISO	Function
GO:0042802	identical protein binding	21220506.	IDA	Function
GO:0042802	identical protein binding	-	ISO	Function
GO:0042803	protein homodimerization activity	-	ISO	Function
GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	-	ISO	Process
GO:0043130	ubiquitin binding	-	ISO	Function
GO:0043231	intracellular membrane-bounded organelle	-	ISO	Component
GO:0044130	negative regulation of growth of symbiont in host	23148214.	IMP	Process
GO:0044753	amphisome	21873635.	IBA	Component
GO:0044753	amphisome	-	ISO	Component
GO:0044754	autolysosome	26284655.	IDA	Component
GO:0044754	autolysosome	-	ISO	Component
GO:0046872	metal ion binding	-	IEA	Function
GO:0051291	protein heterooligomerization	-	ISO	Process
GO:0061635	regulation of protein complex stability	-	ISO	Process
GO:0061912	selective autophagy	-	ISO	Process
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	21873635.	IBA	Function
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	16252010.	IDA	Function
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	-	ISO	Function
GO:0097225	sperm midpiece	22033522.	IDA	Component
GO:0097413	Lewy body	-	ISO	Component
GO:0098780	response to mitochondrial depolarisation	-	ISO	Process
GO:1900273	positive regulation of long-term synaptic potentiation	19004011.	IMP	Process
GO:1903078	positive regulation of protein localization to plasma membrane	19004011.	IMP	Process
GO:1905719	protein localization to perinuclear region of cytoplasm	-	ISO	Process