EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000021134 (Gene tree)
Gene ID: 20384
Gene Symbol: Srsf5
Alias: Sfrs5
Full Name: serine/arginine-rich splicing factor 5
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Plus strand
Length: 5004 bases
Position: chr12:80945504-80950507
Accession: 98287
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000105981	RRM_1	PF00076.22	2.2e-30	1	2
ENSMUSP00000105981	RRM_1	PF00076.22	2.2e-30	2	2
ENSMUSP00000105985	RRM_1	PF00076.22	2.2e-30	1	2
ENSMUSP00000105985	RRM_1	PF00076.22	2.2e-30	2	2
ENSMUSP00000131323	RRM_1	PF00076.22	2.2e-30	1	2
ENSMUSP00000131323	RRM_1	PF00076.22	2.2e-30	2	2
ENSMUSP00000105980	RRM_1	PF00076.22	2.2e-30	1	2
ENSMUSP00000105980	RRM_1	PF00076.22	2.2e-30	2	2
ENSMUSP00000105983	RRM_1	PF00076.22	2.2e-30	1	2
ENSMUSP00000105983	RRM_1	PF00076.22	2.2e-30	2	2

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
25993413	Label-Free Protein RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression	IC & MEF	2015	Boucas J	DOI: 10.1371/journal.pone.0125745
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000110351	-	1498	XM_006515629	ENSMUSP00000105980	270 (aa)	XP_006515692	Q9D8S5
ENSMUST00000110352	-	1491	-	ENSMUSP00000105981	269 (aa)	-	O35326
ENSMUST00000110354	-	1489	-	ENSMUSP00000105983	270 (aa)	-	Q9D8S5
ENSMUST00000138434	-	547	-	ENSMUSP00000138632	46 (aa)	-	S4R2G3
ENSMUST00000110356	-	1568	-	ENSMUSP00000105985	269 (aa)	-	O35326
ENSMUST00000153056	-	2720	-	-	- (aa)	-	-
ENSMUST00000133783	-	2919	-	-	- (aa)	-	-
ENSMUST00000094693	-	1527	-	ENSMUSP00000131323	269 (aa)	-	O35326
ENSMUST00000151036	-	3482	-	-	- (aa)	-	-
ENSMUST00000152662	-	538	-	-	- (aa)	-	-
ENSMUST00000125814	-	886	-	-	- (aa)	-	-
ENSMUST00000151968	-	489	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000021134's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03040	Spliceosome	KEGG
mmu05168	Herpes simplex virus 1 infection	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000021134's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSMUSG00000021134	Srsf5	89	48.780	ENSMUSG00000029538	Srsf9	68	39.394
ENSMUSG00000021134	Srsf5	89	63.415	ENSMUSG00000016921	Srsf6	50	71.642
ENSMUSG00000021134	Srsf5	96	51.020	ENSMUSG00000018379	Srsf1	80	46.988

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000021134	Srsf5	100	98.162	ENSG00000100650	SRSF5	100	100.000	Homo_sapiens
ENSMUSG00000021134	Srsf5	96	90.909	ENSAPOG00000008642	srsf5b	63	85.405	Acanthochromis_polyacanthus
ENSMUSG00000021134	Srsf5	100	98.162	ENSAMEG00000014574	SRSF5	100	98.162	Ailuropoda_melanoleuca
ENSMUSG00000021134	Srsf5	96	90.909	ENSACIG00000010742	srsf5b	81	75.969	Amphilophus_citrinellus
ENSMUSG00000021134	Srsf5	96	90.909	ENSAOCG00000005719	srsf5b	63	85.405	Amphiprion_ocellaris
ENSMUSG00000021134	Srsf5	96	90.909	ENSAPEG00000007830	srsf5b	63	85.405	Amphiprion_percula
ENSMUSG00000021134	Srsf5	96	90.909	ENSATEG00000019112	srsf5b	63	82.258	Anabas_testudineus
ENSMUSG00000021134	Srsf5	98	93.208	ENSAPLG00000014681	SRSF5	67	94.444	Anas_platyrhynchos
ENSMUSG00000021134	Srsf5	100	95.203	ENSACAG00000005143	SRSF5	67	98.889	Anolis_carolinensis
ENSMUSG00000021134	Srsf5	91	100.000	ENSANAG00000037529	-	95	97.541	Aotus_nancymaae
ENSMUSG00000021134	Srsf5	100	98.155	ENSANAG00000027977	-	100	100.000	Aotus_nancymaae
ENSMUSG00000021134	Srsf5	96	90.909	ENSACLG00000026424	srsf5b	63	84.324	Astatotilapia_calliptera
ENSMUSG00000021134	Srsf5	96	93.182	ENSAMXG00000011932	srsf5b	84	80.000	Astyanax_mexicanus
ENSMUSG00000021134	Srsf5	100	98.162	ENSBTAG00000011596	SRSF5	100	98.162	Bos_taurus
ENSMUSG00000021134	Srsf5	100	98.162	ENSCJAG00000014884	SRSF5	100	100.000	Callithrix_jacchus
ENSMUSG00000021134	Srsf5	100	98.162	ENSCAFG00000016589	SRSF5	100	98.162	Canis_familiaris
ENSMUSG00000021134	Srsf5	100	98.162	ENSCAFG00020005661	SRSF5	100	98.162	Canis_lupus_dingo
ENSMUSG00000021134	Srsf5	100	97.445	ENSCHIG00000016794	SRSF5	100	97.445	Capra_hircus
ENSMUSG00000021134	Srsf5	100	98.175	ENSTSYG00000007786	SRSF5	100	100.000	Carlito_syrichta
ENSMUSG00000021134	Srsf5	100	97.445	ENSCAPG00000008801	SRSF5	100	97.445	Cavia_aperea
ENSMUSG00000021134	Srsf5	100	97.080	ENSCPOG00000039926	SRSF5	100	97.080	Cavia_porcellus
ENSMUSG00000021134	Srsf5	100	98.162	ENSCCAG00000029002	SRSF5	100	100.000	Cebus_capucinus
ENSMUSG00000021134	Srsf5	100	97.794	ENSCATG00000045051	SRSF5	100	100.000	Cercocebus_atys
ENSMUSG00000021134	Srsf5	100	97.426	ENSCLAG00000004755	SRSF5	100	97.426	Chinchilla_lanigera
ENSMUSG00000021134	Srsf5	100	98.162	ENSCSAG00000013041	SRSF5	100	98.162	Chlorocebus_sabaeus
ENSMUSG00000021134	Srsf5	100	95.926	ENSCPBG00000021653	SRSF5	100	95.926	Chrysemys_picta_bellii
ENSMUSG00000021134	Srsf5	100	98.162	ENSCANG00000030560	SRSF5	100	100.000	Colobus_angolensis_palliatus
ENSMUSG00000021134	Srsf5	100	100.000	ENSCGRG00001015339	Srsf5	100	100.000	Cricetulus_griseus_chok1gshd
ENSMUSG00000021134	Srsf5	100	100.000	ENSCGRG00000009833	Srsf5	100	100.000	Cricetulus_griseus_crigri
ENSMUSG00000021134	Srsf5	96	90.909	ENSCSEG00000003801	srsf5b	64	82.353	Cynoglossus_semilaevis
ENSMUSG00000021134	Srsf5	96	90.909	ENSCVAG00000017240	srsf5b	68	76.471	Cyprinodon_variegatus
ENSMUSG00000021134	Srsf5	96	93.182	ENSDARG00000027734	srsf5b	90	82.400	Danio_rerio
ENSMUSG00000021134	Srsf5	100	98.519	ENSDNOG00000006160	SRSF5	100	98.519	Dasypus_novemcinctus
ENSMUSG00000021134	Srsf5	100	98.885	ENSDORG00000003989	Srsf5	100	98.885	Dipodomys_ordii
ENSMUSG00000021134	Srsf5	98	93.333	ENSETEG00000020396	SRSF5	88	90.336	Echinops_telfairi
ENSMUSG00000021134	Srsf5	96	77.273	ENSEBUG00000006229	srsf5b	68	65.730	Eptatretus_burgeri
ENSMUSG00000021134	Srsf5	100	98.162	ENSEASG00005016615	SRSF5	100	98.162	Equus_asinus_asinus
ENSMUSG00000021134	Srsf5	100	97.794	ENSECAG00000026873	SRSF5	100	97.794	Equus_caballus
ENSMUSG00000021134	Srsf5	96	93.182	ENSELUG00000019852	srsf5b	85	69.863	Esox_lucius
ENSMUSG00000021134	Srsf5	100	98.162	ENSFCAG00000008848	SRSF5	99	100.000	Felis_catus
ENSMUSG00000021134	Srsf5	98	95.556	ENSFALG00000004979	SRSF5	67	94.972	Ficedula_albicollis
ENSMUSG00000021134	Srsf5	100	98.519	ENSFDAG00000011562	SRSF5	100	98.519	Fukomys_damarensis
ENSMUSG00000021134	Srsf5	96	90.909	ENSFHEG00000009476	srsf5b	60	84.324	Fundulus_heteroclitus
ENSMUSG00000021134	Srsf5	96	93.182	ENSGMOG00000000595	srsf5b	97	67.117	Gadus_morhua
ENSMUSG00000021134	Srsf5	100	94.424	ENSGALG00000009421	SRSF5	90	90.323	Gallus_gallus
ENSMUSG00000021134	Srsf5	96	90.909	ENSGACG00000007834	srsf5b	86	71.324	Gasterosteus_aculeatus
ENSMUSG00000021134	Srsf5	100	95.926	ENSGAGG00000004447	SRSF5	100	95.926	Gopherus_agassizii
ENSMUSG00000021134	Srsf5	100	98.162	ENSGGOG00000016462	SRSF5	100	100.000	Gorilla_gorilla
ENSMUSG00000021134	Srsf5	96	90.909	ENSHBUG00000012462	srsf5b	93	75.000	Haplochromis_burtoni
ENSMUSG00000021134	Srsf5	100	98.519	ENSHGLG00000010147	SRSF5	100	98.519	Heterocephalus_glaber_female
ENSMUSG00000021134	Srsf5	100	98.519	ENSHGLG00100015328	SRSF5	100	98.519	Heterocephalus_glaber_male
ENSMUSG00000021134	Srsf5	98	82.609	ENSHGLG00100000095	-	62	65.517	Heterocephalus_glaber_male
ENSMUSG00000021134	Srsf5	98	84.444	ENSHCOG00000005592	srsf5b	64	77.128	Hippocampus_comes
ENSMUSG00000021134	Srsf5	100	98.889	ENSSTOG00000020672	SRSF5	100	98.889	Ictidomys_tridecemlineatus
ENSMUSG00000021134	Srsf5	100	98.529	ENSJJAG00000001688	Srsf5	100	98.529	Jaculus_jaculus
ENSMUSG00000021134	Srsf5	96	90.909	ENSKMAG00000020486	srsf5b	84	79.528	Kryptolebias_marmoratus
ENSMUSG00000021134	Srsf5	96	90.909	ENSLBEG00000013647	srsf5b	63	82.353	Labrus_bergylta
ENSMUSG00000021134	Srsf5	98	88.889	ENSLACG00000005874	SRSF5	67	90.608	Latimeria_chalumnae
ENSMUSG00000021134	Srsf5	96	93.182	ENSLOCG00000012438	srsf5b	69	82.703	Lepisosteus_oculatus
ENSMUSG00000021134	Srsf5	100	97.426	ENSLAFG00000005260	SRSF5	100	97.426	Loxodonta_africana
ENSMUSG00000021134	Srsf5	100	98.162	ENSMFAG00000002393	SRSF5	100	100.000	Macaca_fascicularis
ENSMUSG00000021134	Srsf5	100	98.162	ENSMNEG00000030872	SRSF5	100	100.000	Macaca_nemestrina
ENSMUSG00000021134	Srsf5	100	97.794	ENSMLEG00000030017	SRSF5	100	100.000	Mandrillus_leucophaeus
ENSMUSG00000021134	Srsf5	96	90.909	ENSMAMG00000002673	srsf5b	63	80.978	Mastacembelus_armatus
ENSMUSG00000021134	Srsf5	96	90.909	ENSMZEG00005003550	srsf5b	63	84.324	Maylandia_zebra
ENSMUSG00000021134	Srsf5	75	91.045	ENSMGAG00000011835	SRSF5	62	91.429	Meleagris_gallopavo
ENSMUSG00000021134	Srsf5	100	100.000	ENSMAUG00000009544	Srsf5	100	100.000	Mesocricetus_auratus
ENSMUSG00000021134	Srsf5	98	95.556	ENSMICG00000046738	-	95	74.167	Microcebus_murinus
ENSMUSG00000021134	Srsf5	100	98.885	ENSMICG00000037432	-	100	100.000	Microcebus_murinus
ENSMUSG00000021134	Srsf5	100	99.630	ENSMOCG00000013134	Srsf5	100	99.630	Microtus_ochrogaster
ENSMUSG00000021134	Srsf5	96	88.636	ENSMMOG00000000137	srsf5b	93	61.538	Mola_mola
ENSMUSG00000021134	Srsf5	98	95.556	ENSMODG00000011362	SRSF5	67	99.441	Monodelphis_domestica
ENSMUSG00000021134	Srsf5	96	90.909	ENSMALG00000021875	srsf5b	84	75.194	Monopterus_albus
ENSMUSG00000021134	Srsf5	100	100.000	MGP_PahariEiJ_G0029659	Srsf5	100	100.000	Mus_pahari
ENSMUSG00000021134	Srsf5	100	98.162	ENSMPUG00000007458	SRSF5	100	98.162	Mustela_putorius_furo
ENSMUSG00000021134	Srsf5	100	94.624	ENSMLUG00000011939	SRSF5	100	94.624	Myotis_lucifugus
ENSMUSG00000021134	Srsf5	100	99.630	ENSNGAG00000010073	-	100	99.630	Nannospalax_galili
ENSMUSG00000021134	Srsf5	96	90.909	ENSNBRG00000001285	srsf5b	63	83.422	Neolamprologus_brichardi
ENSMUSG00000021134	Srsf5	100	98.162	ENSNLEG00000001615	SRSF5	100	100.000	Nomascus_leucogenys
ENSMUSG00000021134	Srsf5	100	94.643	ENSOPRG00000008286	SRSF5	100	94.643	Ochotona_princeps
ENSMUSG00000021134	Srsf5	100	97.778	ENSODEG00000013469	-	100	97.778	Octodon_degus
ENSMUSG00000021134	Srsf5	98	93.333	ENSODEG00000000700	-	68	97.765	Octodon_degus
ENSMUSG00000021134	Srsf5	96	90.909	ENSONIG00000005759	srsf5b	63	84.324	Oreochromis_niloticus
ENSMUSG00000021134	Srsf5	100	92.593	ENSOANG00000013336	SRSF5	89	92.857	Ornithorhynchus_anatinus
ENSMUSG00000021134	Srsf5	100	96.377	ENSOCUG00000009274	SRSF5	100	96.377	Oryctolagus_cuniculus
ENSMUSG00000021134	Srsf5	96	90.909	ENSORLG00000029854	srsf5b	58	79.787	Oryzias_latipes
ENSMUSG00000021134	Srsf5	96	90.909	ENSORLG00015001720	srsf5b	63	81.818	Oryzias_latipes_hsok
ENSMUSG00000021134	Srsf5	100	98.519	ENSOGAG00000015122	SRSF5	100	98.519	Otolemur_garnettii
ENSMUSG00000021134	Srsf5	100	98.162	ENSPPAG00000029921	SRSF5	100	100.000	Pan_paniscus
ENSMUSG00000021134	Srsf5	100	98.162	ENSPPRG00000012903	SRSF5	99	100.000	Panthera_pardus
ENSMUSG00000021134	Srsf5	100	98.162	ENSPTIG00000018589	SRSF5	99	100.000	Panthera_tigris_altaica
ENSMUSG00000021134	Srsf5	100	98.162	ENSPTRG00000006488	SRSF5	100	100.000	Pan_troglodytes
ENSMUSG00000021134	Srsf5	100	97.794	ENSPANG00000021091	SRSF5	100	100.000	Papio_anubis
ENSMUSG00000021134	Srsf5	100	95.556	ENSPSIG00000012522	SRSF5	100	95.556	Pelodiscus_sinensis
ENSMUSG00000021134	Srsf5	96	90.909	ENSPMGG00000021646	srsf5b	85	81.102	Periophthalmus_magnuspinnatus
ENSMUSG00000021134	Srsf5	100	100.000	ENSPEMG00000020173	Srsf5	100	100.000	Peromyscus_maniculatus_bairdii
ENSMUSG00000021134	Srsf5	96	73.333	ENSPMAG00000007790	srsf5b	67	62.694	Petromyzon_marinus
ENSMUSG00000021134	Srsf5	98	95.556	ENSPCIG00000011877	SRSF5	67	99.441	Phascolarctos_cinereus
ENSMUSG00000021134	Srsf5	96	90.909	ENSPMEG00000012751	srsf5b	84	75.000	Poecilia_mexicana
ENSMUSG00000021134	Srsf5	100	98.162	ENSPPYG00000005945	SRSF5	100	98.162	Pongo_abelii
ENSMUSG00000021134	Srsf5	98	93.333	ENSPCAG00000004405	SRSF5	100	99.315	Procavia_capensis
ENSMUSG00000021134	Srsf5	100	98.889	ENSPCOG00000014442	SRSF5	100	98.889	Propithecus_coquereli
ENSMUSG00000021134	Srsf5	98	95.556	ENSPVAG00000009828	SRSF5	100	76.838	Pteropus_vampyrus
ENSMUSG00000021134	Srsf5	96	90.909	ENSPNYG00000002669	srsf5b	94	75.000	Pundamilia_nyererei
ENSMUSG00000021134	Srsf5	96	93.182	ENSPNAG00000011262	srsf5b	84	79.200	Pygocentrus_nattereri
ENSMUSG00000021134	Srsf5	100	100.000	ENSRNOG00000005513	Srsf5	100	100.000	Rattus_norvegicus
ENSMUSG00000021134	Srsf5	100	98.162	ENSRBIG00000013003	SRSF5	100	100.000	Rhinopithecus_bieti
ENSMUSG00000021134	Srsf5	100	98.162	ENSRROG00000043407	SRSF5	100	100.000	Rhinopithecus_roxellana
ENSMUSG00000021134	Srsf5	100	98.162	ENSSBOG00000030784	SRSF5	100	100.000	Saimiri_boliviensis_boliviensis
ENSMUSG00000021134	Srsf5	98	95.556	ENSSHAG00000002871	SRSF5	67	99.441	Sarcophilus_harrisii
ENSMUSG00000021134	Srsf5	96	90.909	ENSSMAG00000019728	srsf5b	61	79.695	Scophthalmus_maximus
ENSMUSG00000021134	Srsf5	96	90.909	ENSSDUG00000005766	srsf5b	65	81.081	Seriola_dumerili
ENSMUSG00000021134	Srsf5	96	90.909	ENSSLDG00000023255	srsf5b	84	75.000	Seriola_lalandi_dorsalis
ENSMUSG00000021134	Srsf5	100	89.259	ENSSARG00000001059	SRSF5	88	88.235	Sorex_araneus
ENSMUSG00000021134	Srsf5	96	97.727	ENSSPUG00000002464	SRSF5	90	91.729	Sphenodon_punctatus
ENSMUSG00000021134	Srsf5	96	90.909	ENSSPAG00000015325	srsf5b	63	84.865	Stegastes_partitus
ENSMUSG00000021134	Srsf5	100	98.897	ENSSSCG00000032583	SRSF5	100	98.897	Sus_scrofa
ENSMUSG00000021134	Srsf5	98	95.556	ENSTGUG00000011425	SRSF5	67	94.972	Taeniopygia_guttata
ENSMUSG00000021134	Srsf5	96	88.636	ENSTRUG00000017811	srsf5b	59	84.153	Takifugu_rubripes
ENSMUSG00000021134	Srsf5	96	88.636	ENSTNIG00000016411	srsf5b	66	84.153	Tetraodon_nigroviridis
ENSMUSG00000021134	Srsf5	98	95.556	ENSTBEG00000001972	SRSF5	65	97.765	Tupaia_belangeri
ENSMUSG00000021134	Srsf5	99	97.436	ENSTTRG00000003318	SRSF5	100	97.436	Tursiops_truncatus
ENSMUSG00000021134	Srsf5	100	98.162	ENSUAMG00000014184	SRSF5	100	98.162	Ursus_americanus
ENSMUSG00000021134	Srsf5	100	98.155	ENSUMAG00000009827	SRSF5	100	98.155	Ursus_maritimus
ENSMUSG00000021134	Srsf5	100	98.889	ENSVPAG00000006448	SRSF5	100	98.889	Vicugna_pacos
ENSMUSG00000021134	Srsf5	100	98.162	ENSVVUG00000003790	SRSF5	100	98.162	Vulpes_vulpes
ENSMUSG00000021134	Srsf5	96	97.727	ENSXETG00000002211	srsf5	67	92.308	Xenopus_tropicalis
ENSMUSG00000021134	Srsf5	96	90.909	ENSXCOG00000001570	srsf5b	92	66.176	Xiphophorus_couchianus
ENSMUSG00000021134	Srsf5	96	90.909	ENSXMAG00000026416	srsf5b	84	75.969	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003723	RNA binding	-	ISO	Function
GO:0005515	protein binding	18758164.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0009611	response to wounding	9857059.	IDA	Process
GO:0016607	nuclear speck	21873635.	IBA	Component
GO:0016607	nuclear speck	18758164.	IDA	Component
GO:0032868	response to insulin	-	ISO	Process
GO:0033120	positive regulation of RNA splicing	-	ISO	Process
GO:0043422	protein kinase B binding	-	ISO	Function
GO:0045292	mRNA cis splicing, via spliceosome	21873635.	IBA	Process
GO:0050733	RS domain binding	15798186.	IPI	Function