EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000021270 (Gene tree)
Gene ID: 15519
Gene Symbol: Hsp90aa1
Alias: Hsp86-1|Hsp89|Hsp90|Hspca|hsp4
Full Name: heat shock protein 90%2C alpha (cytosolic)%2C class A member 1
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 12124
Position: chr12: 110690605-110702728
Accession: 96250
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000021698	-	2852	-	ENSMUSP00000021698	733 (aa)	-	P07901
ENSMUST00000155242	-	711	-	ENSMUSP00000118189	201 (aa)	-	B7ZC50
ENSMUST00000134967	-	487	-	-	- (aa)	-	-
ENSMUST00000129005	-	325	-	-	- (aa)	-	-
ENSMUST00000094361	-	3281	-	ENSMUSP00000091921	733 (aa)	-	P07901
ENSMUST00000145255	-	924	-	-	- (aa)	-	-
ENSMUST00000124156	-	427	-	ENSMUSP00000121138	103 (aa)	-	B7ZC49
ENSMUST00000149189	-	481	-	ENSMUSP00000114201	98 (aa)	-	A2A6A2

Gene Model

Click here to download ENSMUSG00000021270's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04141	Protein processing in endoplasmic reticulum	KEGG
mmu04151	PI3K-Akt signaling pathway	KEGG
mmu04217	Necroptosis	KEGG
mmu04612	Antigen processing and presentation	KEGG
mmu04621	NOD-like receptor signaling pathway	KEGG
mmu04657	IL-17 signaling pathway	KEGG
mmu04659	Th17 cell differentiation	KEGG
mmu04914	Progesterone-mediated oocyte maturation	KEGG
mmu04915	Estrogen signaling pathway	KEGG
mmu05200	Pathways in cancer	KEGG
mmu05215	Prostate cancer	KEGG
mmu05418	Fluid shear stress and atherosclerosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000021270's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000021270	Hsp90aa1	98	73.992	WBGene00000915	daf-21	99	74.409	Caenorhabditis_elegans
ENSMUSG00000021270	Hsp90aa1	93	86.559	FBgn0001233	Hsp83	99	77.191	Drosophila_melanogaster
ENSMUSG00000021270	Hsp90aa1	92	43.523	FBgn0026761	Trap1	89	45.540	Drosophila_melanogaster
ENSMUSG00000021270	Hsp90aa1	100	99.502	ENSG00000080824	HSP90AA1	100	99.045	Homo_sapiens
ENSMUSG00000021270	Hsp90aa1	91	93.443	ENSG00000096384	HSP90AB1	100	84.311	Homo_sapiens
ENSMUSG00000021270	Hsp90aa1	92	54.974	ENSG00000166598	HSP90B1	100	68.750	Homo_sapiens
ENSMUSG00000021270	Hsp90aa1	89	46.448	ENSG00000126602	TRAP1	93	45.320	Homo_sapiens
ENSMUSG00000021270	Hsp90aa1	91	93.443	ENSMUSG00000023944	Hsp90ab1	100	84.720	Mus_musculus
ENSMUSG00000021270	Hsp90aa1	92	53.684	ENSMUSG00000020048	Hsp90b1	88	50.760	Mus_musculus
ENSMUSG00000021270	Hsp90aa1	92	46.277	ENSMUSG00000005981	Trap1	86	45.813	Mus_musculus
ENSMUSG00000021270	Hsp90aa1	92	71.892	YPL240C	HSP82	99	60.610	Saccharomyces_cerevisiae
ENSMUSG00000021270	Hsp90aa1	92	70.811	YMR186W	HSC82	99	60.306	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0001764	neuron migration	-	ISO	Process
GO:0001934	positive regulation of protein phosphorylation	-	ISO	Process
GO:0002134	UTP binding	-	ISO	Function
GO:0002135	CTP binding	-	ISO	Function
GO:0003729	mRNA binding	-	ISO	Function
GO:0005515	protein binding	21873635.	IBA	Function
GO:0005515	protein binding	12855682.12885400.18474241.18566586.22431752.23055941.23184943.29127155.	IPI	Function
GO:0005524	ATP binding	21873635.	IBA	Function
GO:0005524	ATP binding	-	ISO	Function
GO:0005525	GTP binding	-	ISO	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	22431752.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	17908927.22431752.	IDA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	17923681.	IDA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005829	cytosol	12855682.	TAS	Component
GO:0005886	plasma membrane	21873635.	IBA	Component
GO:0006457	protein folding	-	IEA	Process
GO:0006809	nitric oxide biosynthetic process	12855682.	TAS	Process
GO:0006986	response to unfolded protein	12855682.	TAS	Process
GO:0007004	telomere maintenance via telomerase	-	ISO	Process
GO:0009408	response to heat	21873635.	IBA	Process
GO:0009986	cell surface	21873635.	IBA	Component
GO:0009986	cell surface	-	ISO	Component
GO:0010592	positive regulation of lamellipodium assembly	-	ISO	Process
GO:0016020	membrane	-	IEA	Component
GO:0016323	basolateral plasma membrane	-	ISO	Component
GO:0016324	apical plasma membrane	-	ISO	Component
GO:0016887	ATPase activity	-	ISO	Function
GO:0017098	sulfonylurea receptor binding	-	ISO	Function
GO:0019903	protein phosphatase binding	-	ISO	Function
GO:0021955	central nervous system neuron axonogenesis	24286867.	IMP	Process
GO:0030010	establishment of cell polarity	24286867.	IMP	Process
GO:0030235	nitric-oxide synthase regulator activity	21873635.	IBA	Function
GO:0030235	nitric-oxide synthase regulator activity	12855682.	IDA	Function
GO:0030235	nitric-oxide synthase regulator activity	-	ISO	Function
GO:0030911	TPR domain binding	-	ISO	Function
GO:0031396	regulation of protein ubiquitination	-	ISO	Process
GO:0031526	brush border membrane	-	ISO	Component
GO:0031625	ubiquitin protein ligase binding	-	ISO	Function
GO:0032273	positive regulation of protein polymerization	-	ISO	Process
GO:0032564	dATP binding	-	ISO	Function
GO:0032587	ruffle membrane	22431752.	IDA	Component
GO:0032991	protein-containing complex	21873635.	IBA	Component
GO:0032991	protein-containing complex	-	ISO	Component
GO:0033138	positive regulation of peptidyl-serine phosphorylation	24286867.	IMP	Process
GO:0034605	cellular response to heat	21873635.	IBA	Process
GO:0036126	sperm flagellum	-	ISO	Component
GO:0042026	protein refolding	12855682.	TAS	Process
GO:0042802	identical protein binding	-	ISO	Function
GO:0042803	protein homodimerization activity	21873635.	IBA	Function
GO:0042803	protein homodimerization activity	12885400.	IDA	Function
GO:0042803	protein homodimerization activity	-	ISO	Function
GO:0042826	histone deacetylase binding	-	ISO	Function
GO:0043005	neuron projection	-	ISO	Component
GO:0043025	neuronal cell body	21873635.	IBA	Component
GO:0043025	neuronal cell body	24286867.	IDA	Component
GO:0043025	neuronal cell body	-	ISO	Component
GO:0043209	myelin sheath	17634366.	HDA	Component
GO:0043209	myelin sheath	21873635.	IBA	Component
GO:0043209	myelin sheath	-	ISO	Component
GO:0044294	dendritic growth cone	24286867.	IDA	Component
GO:0044295	axonal growth cone	24286867.	IDA	Component
GO:0044325	ion channel binding	-	ISO	Function
GO:0045040	protein import into mitochondrial outer membrane	-	ISO	Process
GO:0045429	positive regulation of nitric oxide biosynthetic process	12855682.	IDA	Process
GO:0045585	positive regulation of cytotoxic T cell differentiation	12855682.	TAS	Process
GO:0045793	positive regulation of cell size	-	ISO	Process
GO:0048156	tau protein binding	-	ISO	Function
GO:0048471	perinuclear region of cytoplasm	21873635.	IBA	Component
GO:0048471	perinuclear region of cytoplasm	24286867.	IDA	Component
GO:0048471	perinuclear region of cytoplasm	-	ISO	Component
GO:0048675	axon extension	24286867.	IMP	Process
GO:0050821	protein stabilization	21873635.	IBA	Process
GO:0050821	protein stabilization	-	ISO	Process
GO:0051020	GTPase binding	-	ISO	Function
GO:0051022	Rho GDP-dissociation inhibitor binding	-	ISO	Function
GO:0051082	unfolded protein binding	21873635.	IBA	Function
GO:0051082	unfolded protein binding	12855682.	TAS	Function
GO:0051131	chaperone-mediated protein complex assembly	-	ISO	Process
GO:0051897	positive regulation of protein kinase B signaling	24286867.	IMP	Process
GO:0051973	positive regulation of telomerase activity	-	ISO	Process
GO:0062023	collagen-containing extracellular matrix	-	ISO	Component
GO:0070182	DNA polymerase binding	-	ISO	Function
GO:0097110	scaffold protein binding	-	ISO	Function
GO:0097226	sperm mitochondrial sheath	-	ISO	Component
GO:0097524	sperm plasma membrane	-	ISO	Component
GO:0097718	disordered domain specific binding	21873635.	IBA	Function
GO:0097718	disordered domain specific binding	-	ISO	Function
GO:1902949	positive regulation of tau-protein kinase activity	-	ISO	Process
GO:1903364	positive regulation of cellular protein catabolic process	-	ISO	Process
GO:1903827	regulation of cellular protein localization	24286867.	IMP	Process
GO:1905323	telomerase holoenzyme complex assembly	-	ISO	Process
GO:1990782	protein tyrosine kinase binding	-	ISO	Function