EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Gene Ontology

Description

Ensembl ID: ENSMUSG00000021313 (Gene tree)
Gene ID: 20191
Gene Symbol: Ryr2
Alias: 9330127I20Rik
Full Name: ryanodine receptor 2%2C cardiac
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 553844
Position: chr13: 11553102-12106945
Accession: 99685
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000021750	-	16814	XM_006516610	ENSMUSP00000021750	4966 (aa)	XP_006516673	E9Q401
ENSMUST00000170156	-	16813	-	ENSMUSP00000127991	4966 (aa)	-	F6U7V1
ENSMUST00000222113	-	920	-	-	- (aa)	-	-
ENSMUST00000221941	-	4117	-	-	- (aa)	-	-
ENSMUST00000222386	-	891	-	-	- (aa)	-	-
ENSMUST00000221341	-	1335	-	-	- (aa)	-	-
ENSMUST00000221916	-	1316	-	-	- (aa)	-	-
ENSMUST00000220712	-	1106	-	ENSMUSP00000152669	369 (aa)	-	A0A1Y7VK09
ENSMUST00000220597	-	4924	-	ENSMUSP00000152051	1020 (aa)	-	Q80ZZ5
ENSMUST00000221018	-	1572	-	-	- (aa)	-	-
ENSMUST00000221527	-	3086	-	ENSMUSP00000152510	1028 (aa)	-	A0A1Y7VJP1
ENSMUST00000222788	-	3794	-	-	- (aa)	-	-
ENSMUST00000221609	-	626	-	-	- (aa)	-	-
ENSMUST00000221890	-	1196	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000021313's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04020	Calcium signaling pathway	KEGG
mmu04024	cAMP signaling pathway	KEGG
mmu04260	Cardiac muscle contraction	KEGG
mmu04261	Adrenergic signaling in cardiomyocytes	KEGG
mmu04371	Apelin signaling pathway	KEGG
mmu04713	Circadian entrainment	KEGG
mmu04911	Insulin secretion	KEGG
mmu04921	Oxytocin signaling pathway	KEGG
mmu04972	Pancreatic secretion	KEGG
mmu05410	Hypertrophic cardiomyopathy (HCM)	KEGG
mmu05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	KEGG
mmu05414	Dilated cardiomyopathy (DCM)	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000021313's network

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001666	response to hypoxia	19120137.	IDA	Process
GO:0002027	regulation of heart rate	17872467.	IMP	Process
GO:0002027	regulation of heart rate	-	ISO	Process
GO:0003143	embryonic heart tube morphogenesis	9628868.	IMP	Process
GO:0003220	left ventricular cardiac muscle tissue morphogenesis	17431507.	IMP	Process
GO:0003300	cardiac muscle hypertrophy	17431507.	IMP	Process
GO:0005216	ion channel activity	-	IEA	Function
GO:0005219	ryanodine-sensitive calcium-release channel activity	21873635.	IBA	Function
GO:0005219	ryanodine-sensitive calcium-release channel activity	14593104.17431507.	IDA	Function
GO:0005219	ryanodine-sensitive calcium-release channel activity	-	ISO	Function
GO:0005262	calcium channel activity	9628868.	IDA	Function
GO:0005509	calcium ion binding	21873635.	IBA	Function
GO:0005513	detection of calcium ion	-	ISO	Process
GO:0005515	protein binding	16481613.20479242.21788490.22939628.23540699.24805197.24952909.	IPI	Function
GO:0005516	calmodulin binding	17431507.	IDA	Function
GO:0005516	calmodulin binding	-	ISO	Function
GO:0005635	nuclear envelope	-	ISO	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005783	endoplasmic reticulum	-	ISO	Component
GO:0005790	smooth endoplasmic reticulum	21873635.	IBA	Component
GO:0005790	smooth endoplasmic reticulum	23454728.	IDA	Component
GO:0005886	plasma membrane	21873635.	IBA	Component
GO:0005886	plasma membrane	-	ISO	Component
GO:0006811	ion transport	-	IEA	Process
GO:0006816	calcium ion transport	10473538.14593104.	IDA	Process
GO:0006816	calcium ion transport	9628868.	IMP	Process
GO:0006816	calcium ion transport	16204356.	IPI	Process
GO:0006816	calcium ion transport	-	ISO	Process
GO:0006874	cellular calcium ion homeostasis	9628868.	IMP	Process
GO:0007275	multicellular organism development	-	IEA	Process
GO:0010460	positive regulation of heart rate	12089338.17431507.	IMP	Process
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	12837242.	IGI	Process
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	-	ISO	Process
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	20226167.	IDA	Process
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	12089338.	IMP	Process
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	-	ISO	Process
GO:0014850	response to muscle activity	-	ISO	Process
GO:0015278	calcium-release channel activity	10473538.	IDA	Function
GO:0015278	calcium-release channel activity	-	ISO	Function
GO:0016020	membrane	17431507.	IDA	Component
GO:0016020	membrane	-	ISO	Component
GO:0016021	integral component of membrane	14593104.	IC	Component
GO:0016529	sarcoplasmic reticulum	12919952.21788490.22406107.	IDA	Component
GO:0016529	sarcoplasmic reticulum	-	ISO	Component
GO:0019722	calcium-mediated signaling	9628868.	IMP	Process
GO:0019899	enzyme binding	16213210.20080623.22406107.	IPI	Function
GO:0019899	enzyme binding	-	ISO	Function
GO:0019901	protein kinase binding	12676814.	IPI	Function
GO:0030017	sarcomere	20226167.	IDA	Component
GO:0030018	Z disc	21873635.	IBA	Component
GO:0030018	Z disc	16204356.19383796.	IDA	Component
GO:0030018	Z disc	-	ISO	Component
GO:0030018	Z disc	-	ISO	Component
GO:0030509	BMP signaling pathway	17360443.	IDA	Process
GO:0030659	cytoplasmic vesicle membrane	21873635.	IBA	Component
GO:0031000	response to caffeine	10473538.14593104.	IDA	Process
GO:0031000	response to caffeine	-	ISO	Process
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	-	ISO	Component
GO:0031672	A band	-	ISO	Component
GO:0032026	response to magnesium ion	-	ISO	Process
GO:0032991	protein-containing complex	18468998.	ISO	Component
GO:0033017	sarcoplasmic reticulum membrane	21873635.	IBA	Component
GO:0033017	sarcoplasmic reticulum membrane	14592808.16481613.	IDA	Component
GO:0033017	sarcoplasmic reticulum membrane	-	ISO	Component
GO:0034220	ion transmembrane transport	-	ISO	Process
GO:0034236	protein kinase A catalytic subunit binding	-	ISO	Function
GO:0034237	protein kinase A regulatory subunit binding	-	ISO	Function
GO:0034704	calcium channel complex	21873635.	IBA	Component
GO:0034704	calcium channel complex	16213210.	IDA	Component
GO:0034704	calcium channel complex	-	ISO	Component
GO:0035584	calcium-mediated signaling using intracellular calcium source	-	ISO	Process
GO:0035994	response to muscle stretch	-	ISO	Process
GO:0042383	sarcolemma	21873635.	IBA	Component
GO:0042383	sarcolemma	-	ISO	Component
GO:0042802	identical protein binding	12324472.20427316.	IPI	Function
GO:0042802	identical protein binding	-	ISO	Function
GO:0043005	neuron projection	-	ISO	Component
GO:0043621	protein self-association	10473538.	IMP	Function
GO:0043924	suramin binding	-	ISO	Function
GO:0048763	calcium-induced calcium release activity	21873635.	IBA	Function
GO:0048763	calcium-induced calcium release activity	-	ISO	Function
GO:0051209	release of sequestered calcium ion into cytosol	21873635.	IBA	Process
GO:0051209	release of sequestered calcium ion into cytosol	-	ISO	Process
GO:0051284	positive regulation of sequestering of calcium ion	-	ISO	Process
GO:0051480	regulation of cytosolic calcium ion concentration	-	ISO	Process
GO:0051481	negative regulation of cytosolic calcium ion concentration	-	ISO	Process
GO:0051592	response to calcium ion	-	ISO	Process
GO:0051775	response to redox state	-	ISO	Process
GO:0055085	transmembrane transport	-	IEA	Process
GO:0055117	regulation of cardiac muscle contraction	-	ISO	Process
GO:0060048	cardiac muscle contraction	-	ISO	Process
GO:0060070	canonical Wnt signaling pathway	17360443.	IDA	Process
GO:0060401	cytosolic calcium ion transport	17431507.	IMP	Process
GO:0060402	calcium ion transport into cytosol	-	ISO	Process
GO:0070296	sarcoplasmic reticulum calcium ion transport	-	ISO	Process
GO:0070588	calcium ion transmembrane transport	21673970.	IMP	Process
GO:0070588	calcium ion transmembrane transport	-	ISO	Process
GO:0071313	cellular response to caffeine	9628868.12089338.22406107.	IDA	Process
GO:0071313	cellular response to caffeine	-	ISO	Process
GO:0071421	manganese ion transmembrane transport	-	ISO	Process
GO:0071872	cellular response to epinephrine stimulus	17872467.	IMP	Process
GO:0072599	establishment of protein localization to endoplasmic reticulum	-	ISO	Process
GO:0086005	ventricular cardiac muscle cell action potential	17872467.	IMP	Process
GO:0086029	Purkinje myocyte to ventricular cardiac muscle cell signaling	17872467.	IMP	Process
GO:0097050	type B pancreatic cell apoptotic process	15044459.	IMP	Process
GO:0097050	type B pancreatic cell apoptotic process	-	ISO	Process
GO:0097110	scaffold protein binding	-	ISO	Function
GO:0097159	organic cyclic compound binding	17431507.	IPI	Function
GO:0098735	positive regulation of the force of heart contraction	-	ISO	Process
GO:0098904	regulation of AV node cell action potential	-	ISO	Process
GO:0098907	regulation of SA node cell action potential	-	ISO	Process
GO:0098910	regulation of atrial cardiac muscle cell action potential	-	ISO	Process
GO:0098911	regulation of ventricular cardiac muscle cell action potential	-	ISO	Process
GO:1901896	positive regulation of calcium-transporting ATPase activity	-	ISO	Process