EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000021823 (Gene tree)
Gene ID: 22330
Gene Symbol: Vcl
Alias: metavinculin
Full Name: vinculin
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 104279
Position: chr14: 20929398-21033676
Accession: 98927
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000226113	-	3934	-	-	- (aa)	-	-
ENSMUST00000022369	-	5267	XM_006518922	ENSMUSP00000022369	1066 (aa)	XP_006518985	Q64727
ENSMUST00000224380	-	446	-	ENSMUSP00000153447	149 (aa)	-	A0A286YDJ4

Gene Model

Click here to download ENSMUSG00000021823's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04510	Focal adhesion	KEGG
mmu04520	Adherens junction	KEGG
mmu04670	Leukocyte transendothelial migration	KEGG
mmu04810	Regulation of actin cytoskeleton	KEGG
mmu05100	Bacterial invasion of epithelial cells	KEGG
mmu05146	Amoebiasis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000021823's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000021823	Vcl	100	99.343	ENSG00000035403	VCL	100	99.343	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001725	stress fiber	-	ISO	Component
GO:0002009	morphogenesis of an epithelium	-	ISO	Process
GO:0002102	podosome	17893324.	IDA	Component
GO:0002162	dystroglycan binding	-	ISO	Function
GO:0003779	actin binding	-	IEA	Function
GO:0005198	structural molecule activity	-	IEA	Function
GO:0005515	protein binding	10085297.15102471.20308429.23055941.23260139.24413171.	IPI	Function
GO:0005737	cytoplasm	24036928.	IDA	Component
GO:0005856	cytoskeleton	-	IEA	Component
GO:0005884	actin filament	-	ISO	Component
GO:0005886	plasma membrane	16481394.	IDA	Component
GO:0005911	cell-cell junction	14657280.22984613.	IDA	Component
GO:0005912	adherens junction	12203715.	IDA	Component
GO:0005913	cell-cell adherens junction	-	ISO	Component
GO:0005916	fascia adherens	11732910.16481394.	IDA	Component
GO:0005925	focal adhesion	15883197.24036928.25217619.	IDA	Component
GO:0005925	focal adhesion	29162887.	ISO	Component
GO:0005925	focal adhesion	-	ISO	Component
GO:0007155	cell adhesion	12473693.	IDA	Process
GO:0014704	intercalated disc	-	ISO	Component
GO:0015629	actin cytoskeleton	21048959.	IDA	Component
GO:0016020	membrane	-	IEA	Component
GO:0017048	Rho GTPase binding	-	ISO	Function
GO:0030018	Z disc	-	ISO	Component
GO:0030032	lamellipodium assembly	12473693.	IDA	Process
GO:0030054	cell junction	-	IEA	Component
GO:0030334	regulation of cell migration	12473693.	IDA	Process
GO:0031625	ubiquitin protein ligase binding	-	ISO	Function
GO:0032991	protein-containing complex	-	ISO	Component
GO:0034333	adherens junction assembly	-	ISO	Process
GO:0034394	protein localization to cell surface	-	ISO	Process
GO:0042383	sarcolemma	26359501.	IDA	Component
GO:0042383	sarcolemma	-	ISO	Component
GO:0043034	costamere	15128702.	IDA	Component
GO:0043034	costamere	-	ISO	Component
GO:0043297	apical junction assembly	-	ISO	Process
GO:0045121	membrane raft	-	ISO	Component
GO:0045294	alpha-catenin binding	-	ISO	Function
GO:0048675	axon extension	24623780.	IGI	Process
GO:0051015	actin filament binding	-	IEA	Function
GO:0090136	epithelial cell-cell adhesion	-	ISO	Process