EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000023944 (Gene tree)
Gene ID: 15516
Gene Symbol: Hsp90ab1
Alias: C81438|Hsp84|Hsp84-1|Hsp90|Hspcb
Full Name: heat shock protein 90 alpha (cytosolic)%2C class B member 1
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 5497
Position: chr17: 45567775-45573271
Accession: 96247
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
25993413	Label-Free Protein RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression	IC & MEF	2015	Boucas J	DOI: 10.1371/journal.pone.0125745
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000146770	-	685	-	-	- (aa)	-	-
ENSMUST00000130406	-	351	-	ENSMUSP00000119678	76 (aa)	-	D3Z1R1
ENSMUST00000163966	-	703	-	ENSMUSP00000131601	112 (aa)	-	E9PX27
ENSMUST00000151306	-	764	-	-	- (aa)	-	-
ENSMUST00000024739	-	2520	-	ENSMUSP00000024739	724 (aa)	-	P11499
ENSMUST00000165127	-	572	-	ENSMUSP00000126239	161 (aa)	-	E9Q0C3
ENSMUST00000145205	-	797	-	-	- (aa)	-	-
ENSMUST00000166469	-	656	-	ENSMUSP00000127338	189 (aa)	-	E9Q3D6

Gene Model

Click here to download ENSMUSG00000023944's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04141	Protein processing in endoplasmic reticulum	KEGG
mmu04151	PI3K-Akt signaling pathway	KEGG
mmu04217	Necroptosis	KEGG
mmu04612	Antigen processing and presentation	KEGG
mmu04621	NOD-like receptor signaling pathway	KEGG
mmu04657	IL-17 signaling pathway	KEGG
mmu04659	Th17 cell differentiation	KEGG
mmu04914	Progesterone-mediated oocyte maturation	KEGG
mmu04915	Estrogen signaling pathway	KEGG
mmu05200	Pathways in cancer	KEGG
mmu05215	Prostate cancer	KEGG
mmu05418	Fluid shear stress and atherosclerosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000023944's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000023944	Hsp90ab1	94	88.372	WBGene00000915	daf-21	99	75.664	Caenorhabditis_elegans
ENSMUSG00000023944	Hsp90ab1	94	93.023	FBgn0001233	Hsp83	99	78.481	Drosophila_melanogaster
ENSMUSG00000023944	Hsp90ab1	93	48.148	FBgn0026761	Trap1	88	46.154	Drosophila_melanogaster
ENSMUSG00000023944	Hsp90ab1	100	100.000	ENSG00000096384	HSP90AB1	100	99.586	Homo_sapiens
ENSMUSG00000023944	Hsp90ab1	100	85.656	ENSG00000080824	HSP90AA1	98	86.555	Homo_sapiens
ENSMUSG00000023944	Hsp90ab1	95	59.722	ENSG00000166598	HSP90B1	100	70.833	Homo_sapiens
ENSMUSG00000023944	Hsp90ab1	86	58.333	ENSG00000126602	TRAP1	93	46.411	Homo_sapiens
ENSMUSG00000023944	Hsp90ab1	100	84.720	ENSMUSG00000021270	Hsp90aa1	91	93.443	Mus_musculus
ENSMUSG00000023944	Hsp90ab1	87	65.152	ENSMUSG00000020048	Hsp90b1	89	49.699	Mus_musculus
ENSMUSG00000023944	Hsp90ab1	86	58.333	ENSMUSG00000005981	Trap1	86	46.411	Mus_musculus
ENSMUSG00000023944	Hsp90ab1	91	87.500	YPL240C	HSP82	99	61.925	Saccharomyces_cerevisiae
ENSMUSG00000023944	Hsp90ab1	91	87.500	YMR186W	HSC82	99	61.571	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0001890	placenta development	10654595.	IMP	Process
GO:0002134	UTP binding	-	ISO	Function
GO:0002135	CTP binding	-	ISO	Function
GO:0003725	double-stranded RNA binding	21266579.	ISO	Function
GO:0005515	protein binding	21873635.	IBA	Function
GO:0005515	protein binding	11751894.11809749.17475835.17517623.21689689.22579285.23055941.23428871.	IPI	Function
GO:0005524	ATP binding	21873635.	IBA	Function
GO:0005524	ATP binding	-	ISO	Function
GO:0005525	GTP binding	-	ISO	Function
GO:0005576	extracellular region	-	ISO	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	17908927.	IDA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005739	mitochondrion	14651853.	HDA	Component
GO:0005765	lysosomal membrane	-	ISO	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005886	plasma membrane	-	IEA	Component
GO:0006457	protein folding	-	IEA	Process
GO:0007004	telomere maintenance via telomerase	-	ISO	Process
GO:0008144	drug binding	-	ISO	Function
GO:0008180	COP9 signalosome	-	ISO	Component
GO:0009986	cell surface	-	ISO	Component
GO:0010033	response to organic substance	17475835.	IDA	Process
GO:0016020	membrane	-	IEA	Component
GO:0016234	inclusion body	-	ISO	Component
GO:0016323	basolateral plasma membrane	-	ISO	Component
GO:0016324	apical plasma membrane	-	ISO	Component
GO:0017098	sulfonylurea receptor binding	-	ISO	Function
GO:0019062	virion attachment to host cell	-	ISO	Process
GO:0019887	protein kinase regulator activity	21855797.	IMP	Function
GO:0019900	kinase binding	21855797.	IPI	Function
GO:0019900	kinase binding	-	ISO	Function
GO:0019901	protein kinase binding	21873635.	IBA	Function
GO:0019901	protein kinase binding	17517623.	IPI	Function
GO:0021955	central nervous system neuron axonogenesis	24286867.	IMP	Process
GO:0030010	establishment of cell polarity	24286867.	IMP	Process
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	-	ISO	Process
GO:0031072	heat shock protein binding	-	ISO	Function
GO:0031396	regulation of protein ubiquitination	-	ISO	Process
GO:0031526	brush border membrane	-	ISO	Component
GO:0031625	ubiquitin protein ligase binding	-	ISO	Function
GO:0032092	positive regulation of protein binding	-	ISO	Process
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	-	ISO	Process
GO:0032516	positive regulation of phosphoprotein phosphatase activity	-	ISO	Process
GO:0032564	dATP binding	-	ISO	Function
GO:0032991	protein-containing complex	-	ISO	Component
GO:0033138	positive regulation of peptidyl-serine phosphorylation	24286867.	IMP	Process
GO:0034751	aryl hydrocarbon receptor complex	-	ISO	Component
GO:0042277	peptide binding	-	ISO	Function
GO:0042802	identical protein binding	-	ISO	Function
GO:0042803	protein homodimerization activity	-	ISO	Function
GO:0042826	histone deacetylase binding	-	ISO	Function
GO:0043008	ATP-dependent protein binding	-	ISO	Function
GO:0043025	neuronal cell body	24286867.	IDA	Component
GO:0043066	negative regulation of apoptotic process	17475835.	IMP	Process
GO:0043524	negative regulation of neuron apoptotic process	-	ISO	Process
GO:0044294	dendritic growth cone	24286867.	IDA	Component
GO:0044295	axonal growth cone	24286867.	IDA	Component
GO:0044325	ion channel binding	-	ISO	Function
GO:0045597	positive regulation of cell differentiation	-	ISO	Process
GO:0045793	positive regulation of cell size	-	ISO	Process
GO:0046983	protein dimerization activity	-	ISO	Function
GO:0048156	tau protein binding	17517623.	IPI	Function
GO:0048471	perinuclear region of cytoplasm	24286867.	IDA	Component
GO:0048675	axon extension	24286867.	IMP	Process
GO:0051082	unfolded protein binding	-	IEA	Function
GO:0051131	chaperone-mediated protein complex assembly	-	ISO	Process
GO:0051248	negative regulation of protein metabolic process	-	ISO	Process
GO:0051897	positive regulation of protein kinase B signaling	24286867.	IMP	Process
GO:0051973	positive regulation of telomerase activity	-	ISO	Process
GO:0070182	DNA polymerase binding	-	ISO	Function
GO:0071157	negative regulation of cell cycle arrest	-	ISO	Process
GO:0071353	cellular response to interleukin-4	9798653.	IDA	Process
GO:0071902	positive regulation of protein serine/threonine kinase activity	-	ISO	Process
GO:0097435	supramolecular fiber organization	-	ISO	Process
GO:0097718	disordered domain specific binding	-	ISO	Function
GO:1901389	negative regulation of transforming growth factor beta activation	-	ISO	Process
GO:1901799	negative regulation of proteasomal protein catabolic process	21873635.	IBA	Process
GO:1901799	negative regulation of proteasomal protein catabolic process	17517623.	IMP	Process
GO:1901799	negative regulation of proteasomal protein catabolic process	-	ISO	Process
GO:1903660	negative regulation of complement-dependent cytotoxicity	-	ISO	Process
GO:1903827	regulation of cellular protein localization	21873635.	IBA	Process
GO:1903827	regulation of cellular protein localization	24286867.	IMP	Process
GO:1904031	positive regulation of cyclin-dependent protein kinase activity	17517623.	IMP	Process
GO:1904031	positive regulation of cyclin-dependent protein kinase activity	-	ISO	Process
GO:1905323	telomerase holoenzyme complex assembly	-	ISO	Process
GO:1990226	histone methyltransferase binding	-	ISO	Function
GO:1990565	HSP90-CDC37 chaperone complex	21855797.	IDA	Component
GO:1990565	HSP90-CDC37 chaperone complex	-	ISO	Component
GO:1990913	sperm head plasma membrane	-	ISO	Component
GO:1990917	ooplasm	-	ISO	Component
GO:2000010	positive regulation of protein localization to cell surface	-	ISO	Process