EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000024151 (Gene tree)
Gene ID: 17685
Gene Symbol: Msh2
Alias: -
Full Name: mutS homolog 2
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 51384
Position: chr17: 87672330-87723713
Accession: 101816
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000172596	-	409	-	-	- (aa)	-	-
ENSMUST00000024967	-	3283	-	ENSMUSP00000024967	935 (aa)	-	P43247
ENSMUST00000173097	-	2502	-	-	- (aa)	-	-
ENSMUST00000174240	-	1752	-	-	- (aa)	-	-
ENSMUST00000174703	-	510	-	ENSMUSP00000133488	68 (aa)	-	G3UWZ8
ENSMUST00000172855	-	630	-	ENSMUSP00000133650	210 (aa)	-	G3UXD8

Gene Model

Click here to download ENSMUSG00000024151's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu01524	Platinum drug resistance	KEGG
mmu03430	Mismatch repair	KEGG
mmu05200	Pathways in cancer	KEGG
mmu05210	Colorectal cancer	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000024151's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000024151	Msh2	99	92.803	ENSG00000095002	MSH2	99	93.128	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0000287	magnesium ion binding	-	ISO	Function
GO:0000400	four-way junction DNA binding	21873635.	IBA	Function
GO:0000400	four-way junction DNA binding	-	ISO	Function
GO:0001701	in utero embryonic development	9288110.	IGI	Process
GO:0001701	in utero embryonic development	9425892.	IGI	Process
GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	12743174.	IGI	Process
GO:0003677	DNA binding	10545954.	IMP	Function
GO:0003677	DNA binding	-	ISO	Function
GO:0003682	chromatin binding	-	ISO	Function
GO:0003684	damaged DNA binding	21873635.	IBA	Function
GO:0003684	damaged DNA binding	7628020.10545954.	IMP	Function
GO:0003690	double-stranded DNA binding	-	ISO	Function
GO:0003697	single-stranded DNA binding	-	ISO	Function
GO:0005524	ATP binding	21873635.	IBA	Function
GO:0005524	ATP binding	-	ISO	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	7628020.	IC	Component
GO:0005634	nucleus	9443401.14744764.	IDA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005694	chromosome	-	IEA	Component
GO:0006119	oxidative phosphorylation	16805809.	IMP	Process
GO:0006281	DNA repair	12687013.	IMP	Process
GO:0006281	DNA repair	-	ISO	Process
GO:0006298	mismatch repair	21873635.	IBA	Process
GO:0006298	mismatch repair	9157971.9244348.	IDA	Process
GO:0006298	mismatch repair	16728433.	IGI	Process
GO:0006298	mismatch repair	7628020.8706033.9288110.9697842.10581038.10874005.10992298.11046134.11890935.12531017.14744764.16728433.17331550.23071719.	IMP	Process
GO:0006298	mismatch repair	11555625.23603115.	ISO	Process
GO:0006301	postreplication repair	21873635.	IBA	Process
GO:0006301	postreplication repair	7628020.	IMP	Process
GO:0006301	postreplication repair	-	ISO	Process
GO:0006302	double-strand break repair	21873635.	IBA	Process
GO:0006302	double-strand break repair	17912366.	IMP	Process
GO:0006974	cellular response to DNA damage stimulus	10097137.10720738.11429706.14744764.	IMP	Process
GO:0007049	cell cycle	-	IEA	Process
GO:0007050	cell cycle arrest	12687013.	IMP	Process
GO:0007281	germ cell development	17912366.	IMP	Process
GO:0008022	protein C-terminus binding	-	ISO	Function
GO:0008094	DNA-dependent ATPase activity	21873635.	IBA	Function
GO:0008340	determination of adult lifespan	10545954.	IMP	Process
GO:0008584	male gonad development	17912366.	IMP	Process
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	10097137.14744764.	IMP	Process
GO:0010165	response to X-ray	21873635.	IBA	Process
GO:0010165	response to X-ray	12687013.	IMP	Process
GO:0010224	response to UV-B	21873635.	IBA	Process
GO:0010224	response to UV-B	15166087.	IMP	Process
GO:0016446	somatic hypermutation of immunoglobulin genes	15494304.	IGI	Process
GO:0016446	somatic hypermutation of immunoglobulin genes	9607916.9697842.9697843.14568978.	IMP	Process
GO:0016446	somatic hypermutation of immunoglobulin genes	9607915.	IMP	Process
GO:0016447	somatic recombination of immunoglobulin gene segments	15494304.	IGI	Process
GO:0016447	somatic recombination of immunoglobulin gene segments	11828012.14563316.14568978.15955838.	IMP	Process
GO:0016887	ATPase activity	14568978.	IMP	Function
GO:0016887	ATPase activity	-	ISO	Function
GO:0019237	centromeric DNA binding	16260499.	IDA	Function
GO:0019724	B cell mediated immunity	9697843.9927509.	IMP	Process
GO:0019899	enzyme binding	-	ISO	Function
GO:0019901	protein kinase binding	-	ISO	Function
GO:0030183	B cell differentiation	9697843.	IMP	Process
GO:0030983	mismatched DNA binding	7550317.14744764.	IMP	Function
GO:0030983	mismatched DNA binding	-	ISO	Function
GO:0031573	intra-S DNA damage checkpoint	21873635.	IBA	Process
GO:0031573	intra-S DNA damage checkpoint	15533840.	IGI	Process
GO:0032137	guanine/thymine mispair binding	21873635.	IBA	Function
GO:0032137	guanine/thymine mispair binding	16713580.	IDA	Function
GO:0032137	guanine/thymine mispair binding	16713580.	ISO	Function
GO:0032137	guanine/thymine mispair binding	-	ISO	Function
GO:0032139	dinucleotide insertion or deletion binding	-	ISO	Function
GO:0032142	single guanine insertion binding	-	ISO	Function
GO:0032143	single thymine insertion binding	21873635.	IBA	Function
GO:0032143	single thymine insertion binding	-	ISO	Function
GO:0032181	dinucleotide repeat insertion binding	-	ISO	Function
GO:0032300	mismatch repair complex	21873635.	IBA	Component
GO:0032301	MutSalpha complex	21873635.	IBA	Component
GO:0032301	MutSalpha complex	16713580.	IDA	Component
GO:0032301	MutSalpha complex	-	ISO	Component
GO:0032302	MutSbeta complex	21873635.	IBA	Component
GO:0032302	MutSbeta complex	-	ISO	Component
GO:0032357	oxidized purine DNA binding	-	ISO	Function
GO:0032405	MutLalpha complex binding	-	ISO	Function
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	21873635.	IBA	Process
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	10097137.	IGI	Process
GO:0042803	protein homodimerization activity	-	ISO	Function
GO:0043524	negative regulation of neuron apoptotic process	16805809.	IMP	Process
GO:0043531	ADP binding	-	ISO	Function
GO:0043570	maintenance of DNA repeat elements	21873635.	IBA	Process
GO:0043570	maintenance of DNA repeat elements	-	ISO	Process
GO:0045190	isotype switching	10430621.12743174.	IMP	Process
GO:0045910	negative regulation of DNA recombination	21873635.	IBA	Process
GO:0045910	negative regulation of DNA recombination	7628020.10545954.	IMP	Process
GO:0045910	negative regulation of DNA recombination	-	ISO	Process
GO:0048298	positive regulation of isotype switching to IgA isotypes	10430621.	IMP	Process
GO:0048304	positive regulation of isotype switching to IgG isotypes	10430621.	IMP	Process
GO:0051096	positive regulation of helicase activity	-	ISO	Process
GO:0071168	protein localization to chromatin	-	ISO	Process