EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000024493 (Gene tree)
Gene ID: 107045
Gene Symbol: Lars
Alias: 2310045K21Rik|3110009L02Rik
Full Name: leucyl-tRNA synthetase
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 59773 bases
Position: chr18:42202350-42262122
Accession: 1913808
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000095197	tRNA-synt_1g	PF09334.11	6.1e-17	1	2
ENSMUSP00000095197	tRNA-synt_1g	PF09334.11	6.1e-17	2	2
ENSMUSP00000095197	Anticodon_1	PF08264.13	9.2e-18	1	1
ENSMUSP00000095197	tRNA-synt_1	PF00133.22	9.8e-40	1	2
ENSMUSP00000095197	tRNA-synt_1	PF00133.22	9.8e-40	2	2
ENSMUSP00000095197	tRNA-synt_1e	PF01406.19	4.4e-06	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000097590	-	3856	-	ENSMUSP00000095197	1178 (aa)	-	Q8BMJ2

Gene Model

Click here to download ENSMUSG00000024493's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu00970	Aminoacyl-tRNA biosynthesis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000024493's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000024493	Lars	100	90.068	ENSG00000133706	LARS	100	90.553	Homo_sapiens
ENSMUSG00000024493	Lars	100	77.001	ENSAPOG00000010585	larsb	100	77.718	Acanthochromis_polyacanthus
ENSMUSG00000024493	Lars	99	89.720	ENSAMEG00000017584	LARS	99	89.720	Ailuropoda_melanoleuca
ENSMUSG00000024493	Lars	100	74.958	ENSACIG00000014026	larsb	100	75.042	Amphilophus_citrinellus
ENSMUSG00000024493	Lars	100	76.793	ENSAOCG00000016931	larsb	100	76.793	Amphiprion_ocellaris
ENSMUSG00000024493	Lars	100	76.878	ENSAPEG00000017720	larsb	100	76.878	Amphiprion_percula
ENSMUSG00000024493	Lars	99	74.172	ENSATEG00000010441	larsb	99	74.278	Anabas_testudineus
ENSMUSG00000024493	Lars	96	85.035	ENSAPLG00000008145	LARS	100	85.035	Anas_platyrhynchos
ENSMUSG00000024493	Lars	100	82.683	ENSACAG00000013916	LARS	100	82.767	Anolis_carolinensis
ENSMUSG00000024493	Lars	95	90.374	ENSANAG00000014375	LARS	100	90.374	Aotus_nancymaae
ENSMUSG00000024493	Lars	100	76.793	ENSACLG00000010881	larsb	100	76.793	Astatotilapia_calliptera
ENSMUSG00000024493	Lars	100	78.711	ENSAMXG00000019979	larsb	100	78.711	Astyanax_mexicanus
ENSMUSG00000024493	Lars	100	89.983	ENSBTAG00000006765	LARS	100	89.983	Bos_taurus
ENSMUSG00000024493	Lars	99	55.000	WBGene00003073	lars-1	99	55.000	Caenorhabditis_elegans
ENSMUSG00000024493	Lars	100	89.643	ENSCJAG00000021314	LARS	100	90.285	Callithrix_jacchus
ENSMUSG00000024493	Lars	100	89.813	ENSCAFG00000006431	LARS	100	89.813	Canis_familiaris
ENSMUSG00000024493	Lars	100	89.737	ENSCAFG00020025009	LARS	100	89.737	Canis_lupus_dingo
ENSMUSG00000024493	Lars	100	90.153	ENSCHIG00000014949	LARS	100	90.153	Capra_hircus
ENSMUSG00000024493	Lars	100	89.219	ENSTSYG00000001253	LARS	100	89.219	Carlito_syrichta
ENSMUSG00000024493	Lars	96	71.958	ENSCAPG00000015676	LARS	97	71.958	Cavia_aperea
ENSMUSG00000024493	Lars	100	89.219	ENSCPOG00000012329	LARS	100	89.219	Cavia_porcellus
ENSMUSG00000024493	Lars	100	90.068	ENSCCAG00000020789	LARS	100	90.068	Cebus_capucinus
ENSMUSG00000024493	Lars	97	90.325	ENSCATG00000033463	LARS	100	90.463	Cercocebus_atys
ENSMUSG00000024493	Lars	100	90.153	ENSCLAG00000011193	LARS	100	90.153	Chinchilla_lanigera
ENSMUSG00000024493	Lars	99	90.051	ENSCSAG00000012280	LARS	97	90.051	Chlorocebus_sabaeus
ENSMUSG00000024493	Lars	89	85.475	ENSCHOG00000009309	LARS	90	85.475	Choloepus_hoffmanni
ENSMUSG00000024493	Lars	99	82.993	ENSCPBG00000008415	LARS	99	83.574	Chrysemys_picta_bellii
ENSMUSG00000024493	Lars	99	63.551	ENSCING00000008535	-	98	63.660	Ciona_intestinalis
ENSMUSG00000024493	Lars	99	61.929	ENSCSAVG00000009040	-	100	66.667	Ciona_savignyi
ENSMUSG00000024493	Lars	100	89.983	ENSCANG00000031137	LARS	100	89.983	Colobus_angolensis_palliatus
ENSMUSG00000024493	Lars	93	90.842	ENSCGRG00001004647	Lars	99	90.842	Cricetulus_griseus_chok1gshd
ENSMUSG00000024493	Lars	100	92.869	ENSCGRG00000007284	Lars	100	92.869	Cricetulus_griseus_crigri
ENSMUSG00000024493	Lars	100	75.653	ENSCSEG00000014984	larsb	100	75.758	Cynoglossus_semilaevis
ENSMUSG00000024493	Lars	100	76.793	ENSCVAG00000014685	larsb	100	76.793	Cyprinodon_variegatus
ENSMUSG00000024493	Lars	68	77.472	ENSDARG00000019280	larsb	100	77.472	Danio_rerio
ENSMUSG00000024493	Lars	96	88.147	ENSDNOG00000017963	LARS	100	88.235	Dasypus_novemcinctus
ENSMUSG00000024493	Lars	100	85.339	ENSDORG00000014913	Lars	100	85.339	Dipodomys_ordii
ENSMUSG00000024493	Lars	99	58.953	FBgn0284253	LeuRS	99	58.953	Drosophila_melanogaster
ENSMUSG00000024493	Lars	94	71.906	ENSETEG00000003145	LARS	99	71.906	Echinops_telfairi
ENSMUSG00000024493	Lars	92	59.615	ENSEBUG00000014985	larsb	97	59.489	Eptatretus_burgeri
ENSMUSG00000024493	Lars	100	90.153	ENSEASG00005020569	LARS	100	90.481	Equus_asinus_asinus
ENSMUSG00000024493	Lars	100	90.068	ENSECAG00000008963	LARS	100	90.752	Equus_caballus
ENSMUSG00000024493	Lars	92	74.453	ENSEEUG00000014854	LARS	92	74.453	Erinaceus_europaeus
ENSMUSG00000024493	Lars	100	75.552	ENSELUG00000023311	larsb	100	75.552	Esox_lucius
ENSMUSG00000024493	Lars	99	89.532	ENSFCAG00000008715	LARS	100	90.405	Felis_catus
ENSMUSG00000024493	Lars	100	83.545	ENSFALG00000003209	LARS	93	83.545	Ficedula_albicollis
ENSMUSG00000024493	Lars	100	90.238	ENSFDAG00000020764	LARS	100	90.238	Fukomys_damarensis
ENSMUSG00000024493	Lars	91	76.902	ENSFHEG00000010437	larsb	100	76.722	Fundulus_heteroclitus
ENSMUSG00000024493	Lars	99	74.405	ENSGMOG00000013645	larsb	99	74.490	Gadus_morhua
ENSMUSG00000024493	Lars	100	84.394	ENSGALG00000007494	LARS	100	84.394	Gallus_gallus
ENSMUSG00000024493	Lars	100	75.781	ENSGAFG00000005029	larsb	100	75.781	Gambusia_affinis
ENSMUSG00000024493	Lars	99	75.660	ENSGACG00000020720	larsb	99	75.574	Gasterosteus_aculeatus
ENSMUSG00000024493	Lars	99	82.483	ENSGAGG00000002353	LARS	99	82.483	Gopherus_agassizii
ENSMUSG00000024493	Lars	100	89.898	ENSGGOG00000004103	LARS	100	89.898	Gorilla_gorilla
ENSMUSG00000024493	Lars	99	75.980	ENSHBUG00000003051	larsb	99	77.838	Haplochromis_burtoni
ENSMUSG00000024493	Lars	100	90.323	ENSHGLG00000006937	LARS	100	90.323	Heterocephalus_glaber_female
ENSMUSG00000024493	Lars	100	90.323	ENSHGLG00100002801	LARS	100	90.323	Heterocephalus_glaber_male
ENSMUSG00000024493	Lars	99	75.591	ENSHCOG00000003651	larsb	100	75.591	Hippocampus_comes
ENSMUSG00000024493	Lars	99	77.674	ENSIPUG00000010756	lars	100	77.998	Ictalurus_punctatus
ENSMUSG00000024493	Lars	100	90.747	ENSSTOG00000002356	LARS	100	90.747	Ictidomys_tridecemlineatus
ENSMUSG00000024493	Lars	100	91.002	ENSJJAG00000015265	Lars	100	91.002	Jaculus_jaculus
ENSMUSG00000024493	Lars	100	76.138	ENSKMAG00000009903	larsb	100	76.138	Kryptolebias_marmoratus
ENSMUSG00000024493	Lars	100	76.560	ENSLBEG00000025237	larsb	100	76.560	Labrus_bergylta
ENSMUSG00000024493	Lars	100	78.559	ENSLACG00000009321	LARS	100	78.983	Latimeria_chalumnae
ENSMUSG00000024493	Lars	99	78.535	ENSLOCG00000010442	larsb	99	78.109	Lepisosteus_oculatus
ENSMUSG00000024493	Lars	99	88.851	ENSLAFG00000000318	LARS	100	88.851	Loxodonta_africana
ENSMUSG00000024493	Lars	100	89.983	ENSMFAG00000038685	LARS	100	89.983	Macaca_fascicularis
ENSMUSG00000024493	Lars	100	89.983	ENSMMUG00000029787	LARS	100	89.983	Macaca_mulatta
ENSMUSG00000024493	Lars	99	88.000	ENSMNEG00000044014	LARS	99	88.000	Macaca_nemestrina
ENSMUSG00000024493	Lars	99	90.128	ENSMLEG00000037563	LARS	99	90.128	Mandrillus_leucophaeus
ENSMUSG00000024493	Lars	100	76.371	ENSMAMG00000021385	larsb	100	76.371	Mastacembelus_armatus
ENSMUSG00000024493	Lars	100	76.709	ENSMZEG00005002662	larsb	100	76.709	Maylandia_zebra
ENSMUSG00000024493	Lars	96	84.859	ENSMGAG00000009388	LARS	100	84.859	Meleagris_gallopavo
ENSMUSG00000024493	Lars	99	83.319	ENSMAUG00000003063	Lars	99	83.319	Mesocricetus_auratus
ENSMUSG00000024493	Lars	100	75.722	ENSMICG00000035435	-	100	79.286	Microcebus_murinus
ENSMUSG00000024493	Lars	100	90.577	ENSMICG00000035589	-	100	90.577	Microcebus_murinus
ENSMUSG00000024493	Lars	100	94.907	ENSMOCG00000002092	Lars	100	94.907	Microtus_ochrogaster
ENSMUSG00000024493	Lars	99	74.002	ENSMMOG00000013802	larsb	99	74.109	Mola_mola
ENSMUSG00000024493	Lars	99	79.234	ENSMODG00000010231	LARS	99	79.354	Monodelphis_domestica
ENSMUSG00000024493	Lars	99	75.127	ENSMALG00000018444	larsb	99	75.127	Monopterus_albus
ENSMUSG00000024493	Lars	100	99.151	MGP_CAROLIEiJ_G0022225	Lars	100	99.151	Mus_caroli
ENSMUSG00000024493	Lars	100	98.642	MGP_PahariEiJ_G0018958	Lars	100	98.642	Mus_pahari
ENSMUSG00000024493	Lars	100	99.236	MGP_SPRETEiJ_G0023135	Lars	100	99.236	Mus_spretus
ENSMUSG00000024493	Lars	100	90.238	ENSMPUG00000007844	LARS	100	90.238	Mustela_putorius_furo
ENSMUSG00000024493	Lars	99	89.201	ENSMLUG00000001125	LARS	99	89.201	Myotis_lucifugus
ENSMUSG00000024493	Lars	100	91.256	ENSNGAG00000011596	Lars	100	91.341	Nannospalax_galili
ENSMUSG00000024493	Lars	100	76.962	ENSNBRG00000005764	larsb	100	76.962	Neolamprologus_brichardi
ENSMUSG00000024493	Lars	99	89.106	ENSNLEG00000009816	LARS	99	89.106	Nomascus_leucogenys
ENSMUSG00000024493	Lars	60	80.597	ENSMEUG00000002332	-	60	80.597	Notamacropus_eugenii
ENSMUSG00000024493	Lars	78	90.860	ENSOPRG00000003076	LARS	83	90.860	Ochotona_princeps
ENSMUSG00000024493	Lars	99	87.064	ENSODEG00000004882	LARS	99	87.064	Octodon_degus
ENSMUSG00000024493	Lars	100	77.131	ENSONIG00000008493	larsb	100	77.131	Oreochromis_niloticus
ENSMUSG00000024493	Lars	100	81.657	ENSOANG00000005755	LARS	100	81.657	Ornithorhynchus_anatinus
ENSMUSG00000024493	Lars	100	90.407	ENSOCUG00000015684	LARS	100	90.407	Oryctolagus_cuniculus
ENSMUSG00000024493	Lars	100	76.034	ENSORLG00000001622	larsb	100	76.034	Oryzias_latipes
ENSMUSG00000024493	Lars	100	76.034	ENSORLG00020019950	larsb	100	76.034	Oryzias_latipes_hni
ENSMUSG00000024493	Lars	100	76.118	ENSORLG00015003895	larsb	100	76.118	Oryzias_latipes_hsok
ENSMUSG00000024493	Lars	100	76.118	ENSOMEG00000005677	larsb	100	76.118	Oryzias_melastigma
ENSMUSG00000024493	Lars	96	87.489	ENSOGAG00000008750	LARS	100	87.489	Otolemur_garnettii
ENSMUSG00000024493	Lars	99	89.966	ENSOARG00000002454	-	99	89.966	Ovis_aries
ENSMUSG00000024493	Lars	100	89.898	ENSOARG00000015911	-	99	89.898	Ovis_aries
ENSMUSG00000024493	Lars	99	90.043	ENSPPAG00000027964	LARS	99	90.043	Pan_paniscus
ENSMUSG00000024493	Lars	100	89.898	ENSPPRG00000023492	LARS	100	89.898	Panthera_pardus
ENSMUSG00000024493	Lars	100	89.728	ENSPTIG00000013110	LARS	100	89.728	Panthera_tigris_altaica
ENSMUSG00000024493	Lars	100	89.898	ENSPTRG00000017372	LARS	100	89.898	Pan_troglodytes
ENSMUSG00000024493	Lars	100	90.153	ENSPANG00000002663	LARS	100	90.153	Papio_anubis
ENSMUSG00000024493	Lars	98	77.190	ENSPKIG00000006650	larsb	99	76.122	Paramormyrops_kingsleyae
ENSMUSG00000024493	Lars	99	83.163	ENSPSIG00000015641	LARS	99	83.163	Pelodiscus_sinensis
ENSMUSG00000024493	Lars	68	77.000	ENSPMGG00000019556	LARS	100	77.000	Periophthalmus_magnuspinnatus
ENSMUSG00000024493	Lars	100	91.511	ENSPEMG00000010933	Lars	100	91.511	Peromyscus_maniculatus_bairdii
ENSMUSG00000024493	Lars	51	62.852	ENSPMAG00000005301	larsb	99	62.852	Petromyzon_marinus
ENSMUSG00000024493	Lars	100	84.635	ENSPCIG00000030572	LARS	100	84.635	Phascolarctos_cinereus
ENSMUSG00000024493	Lars	100	76.203	ENSPFOG00000002361	larsb	100	76.203	Poecilia_formosa
ENSMUSG00000024493	Lars	100	76.456	ENSPLAG00000016550	larsb	100	76.456	Poecilia_latipinna
ENSMUSG00000024493	Lars	100	76.118	ENSPMEG00000018422	larsb	100	76.118	Poecilia_mexicana
ENSMUSG00000024493	Lars	100	76.034	ENSPREG00000005668	larsb	100	76.034	Poecilia_reticulata
ENSMUSG00000024493	Lars	99	88.625	ENSPPYG00000015908	LARS	97	88.625	Pongo_abelii
ENSMUSG00000024493	Lars	89	81.081	ENSPCAG00000005621	LARS	99	81.081	Procavia_capensis
ENSMUSG00000024493	Lars	100	88.964	ENSPCOG00000019325	LARS	100	88.964	Propithecus_coquereli
ENSMUSG00000024493	Lars	96	80.546	ENSPVAG00000011237	LARS	100	80.986	Pteropus_vampyrus
ENSMUSG00000024493	Lars	100	76.540	ENSPNYG00000015254	larsb	100	76.540	Pundamilia_nyererei
ENSMUSG00000024493	Lars	100	77.504	ENSPNAG00000027191	larsb	100	77.504	Pygocentrus_nattereri
ENSMUSG00000024493	Lars	100	97.199	ENSRNOG00000018304	Lars	100	97.199	Rattus_norvegicus
ENSMUSG00000024493	Lars	94	88.347	ENSRBIG00000043198	LARS	99	88.347	Rhinopithecus_bieti
ENSMUSG00000024493	Lars	86	46.712	YPL160W	CDC60	93	46.712	Saccharomyces_cerevisiae
ENSMUSG00000024493	Lars	99	87.319	ENSSBOG00000026661	LARS	100	90.769	Saimiri_boliviensis_boliviensis
ENSMUSG00000024493	Lars	100	85.666	ENSSHAG00000006084	LARS	100	85.666	Sarcophilus_harrisii
ENSMUSG00000024493	Lars	97	78.665	ENSSFOG00015018117	larsb	90	78.665	Scleropages_formosus
ENSMUSG00000024493	Lars	88	77.586	ENSSMAG00000004078	larsb	97	77.703	Scophthalmus_maximus
ENSMUSG00000024493	Lars	100	76.624	ENSSDUG00000021142	larsb	100	76.624	Seriola_dumerili
ENSMUSG00000024493	Lars	100	76.793	ENSSLDG00000007054	larsb	100	76.793	Seriola_lalandi_dorsalis
ENSMUSG00000024493	Lars	85	87.143	ENSSARG00000013481	LARS	85	86.861	Sorex_araneus
ENSMUSG00000024493	Lars	100	83.051	ENSSPUG00000013805	LARS	100	83.136	Sphenodon_punctatus
ENSMUSG00000024493	Lars	100	76.624	ENSSPAG00000012124	larsb	100	76.624	Stegastes_partitus
ENSMUSG00000024493	Lars	100	85.908	ENSSSCG00000014411	LARS	100	85.908	Sus_scrofa
ENSMUSG00000024493	Lars	99	83.929	ENSTGUG00000000092	-	99	83.929	Taeniopygia_guttata
ENSMUSG00000024493	Lars	100	76.287	ENSTRUG00000005358	larsb	100	76.287	Takifugu_rubripes
ENSMUSG00000024493	Lars	99	74.068	ENSTNIG00000018214	larsb	99	74.068	Tetraodon_nigroviridis
ENSMUSG00000024493	Lars	91	88.618	ENSTBEG00000003757	LARS	94	88.618	Tupaia_belangeri
ENSMUSG00000024493	Lars	96	87.213	ENSTTRG00000016712	LARS	96	87.213	Tursiops_truncatus
ENSMUSG00000024493	Lars	94	90.090	ENSUAMG00000019907	LARS	99	90.090	Ursus_americanus
ENSMUSG00000024493	Lars	100	89.813	ENSUMAG00000010585	LARS	100	89.813	Ursus_maritimus
ENSMUSG00000024493	Lars	92	90.268	ENSVPAG00000000557	LARS	92	90.268	Vicugna_pacos
ENSMUSG00000024493	Lars	100	89.898	ENSVVUG00000021124	LARS	100	89.898	Vulpes_vulpes
ENSMUSG00000024493	Lars	99	82.612	ENSXETG00000002320	lars	100	82.542	Xenopus_tropicalis
ENSMUSG00000024493	Lars	100	76.118	ENSXMAG00000001454	larsb	100	76.118	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0002161	aminoacyl-tRNA editing activity	-	IEA	Function
GO:0004812	aminoacyl-tRNA ligase activity	-	IEA	Function
GO:0004819	glutamine-tRNA ligase activity	-	ISO	Function
GO:0004823	leucine-tRNA ligase activity	21873635.	IBA	Function
GO:0004823	leucine-tRNA ligase activity	12060739.	IMP	Function
GO:0005096	GTPase activator activity	-	ISO	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005737	cytoplasm	-	ISO	Component
GO:0005764	lysosome	-	ISO	Component
GO:0005783	endoplasmic reticulum	-	ISO	Component
GO:0005829	cytosol	-	ISO	Component
GO:0006412	translation	-	IEA	Process
GO:0006418	tRNA aminoacylation for protein translation	-	IEA	Process
GO:0006425	glutaminyl-tRNA aminoacylation	-	ISO	Process
GO:0006429	leucyl-tRNA aminoacylation	21873635.	IBA	Process
GO:0006429	leucyl-tRNA aminoacylation	12060739.	IDA	Process
GO:0006622	protein targeting to lysosome	-	ISO	Process
GO:0008361	regulation of cell size	-	ISO	Process
GO:0010507	negative regulation of autophagy	-	ISO	Process
GO:0012505	endomembrane system	-	ISO	Component
GO:0016604	nuclear body	-	ISO	Component
GO:0016874	ligase activity	-	IEA	Function
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	12060739.	IDA	Component
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	-	ISO	Component
GO:0034198	cellular response to amino acid starvation	-	ISO	Process
GO:0043547	positive regulation of GTPase activity	-	ISO	Process
GO:0071230	cellular response to amino acid stimulus	-	ISO	Process
GO:0071233	cellular response to leucine	-	ISO	Process
GO:1904263	positive regulation of TORC1 signaling	-	ISO	Process
GO:1990253	cellular response to leucine starvation	-	ISO	Process