EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000024991 (Gene tree)
Gene ID: 13669
Gene Symbol: Eif3a
Alias: A830012B05Rik|Csma|Eif3|Eif3s10
Full Name: eukaryotic translation initiation factor 3%2C subunit A
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 29578
Position: chr19: 60761116-60790693
Accession: 95301
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
25993413	Label-Free Protein RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression	IC & MEF	2015	Boucas J	DOI: 10.1371/journal.pone.0125745
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000025955	-	5176	-	ENSMUSP00000025955	1344 (aa)	-	P23116

Gene Model

Click here to download ENSMUSG00000024991's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03013	RNA transport	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000024991's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000024991	Eif3a	60	39.007	WBGene00001209	egl-45	76	39.199	Caenorhabditis_elegans
ENSMUSG00000024991	Eif3a	100	71.923	ENSDARG00000076815	eif3s10	92	77.380	Danio_rerio
ENSMUSG00000024991	Eif3a	79	45.745	FBgn0037249	eIF3a	99	44.667	Drosophila_melanogaster
ENSMUSG00000024991	Eif3a	100	92.857	ENSG00000107581	EIF3A	100	91.486	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001732	formation of cytoplasmic translation initiation complex	21873635.	IBA	Process
GO:0001732	formation of cytoplasmic translation initiation complex	17581632.	IDA	Process
GO:0001732	formation of cytoplasmic translation initiation complex	-	ISO	Process
GO:0002188	translation reinitiation	21873635.	IBA	Process
GO:0003723	RNA binding	-	ISO	Function
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0003743	translation initiation factor activity	21873635.	IBA	Function
GO:0003743	translation initiation factor activity	17581632.	IDA	Function
GO:0003743	translation initiation factor activity	-	ISO	Function
GO:0005515	protein binding	19114715.	IPI	Function
GO:0005634	nucleus	-	ISO	Component
GO:0005730	nucleolus	-	ISO	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005852	eukaryotic translation initiation factor 3 complex	17581632.	IDA	Component
GO:0005852	eukaryotic translation initiation factor 3 complex	-	ISO	Component
GO:0005856	cytoskeleton	-	IEA	Component
GO:0005874	microtubule	-	ISO	Component
GO:0006412	translation	-	IEA	Process
GO:0006413	translational initiation	-	IEA	Process
GO:0014069	postsynaptic density	25211037.	EXP	Component
GO:0014069	postsynaptic density	25211037.	IDA	Component
GO:0030971	receptor tyrosine kinase binding	-	ISO	Function
GO:0043614	multi-eIF complex	21873635.	IBA	Component
GO:0070373	negative regulation of ERK1 and ERK2 cascade	-	ISO	Process
GO:0071540	eukaryotic translation initiation factor 3 complex, eIF3e	21873635.	IBA	Component
GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m	21873635.	IBA	Component
GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m	24003236.	IDA	Component
GO:0075522	IRES-dependent viral translational initiation	-	ISO	Process
GO:0075525	viral translational termination-reinitiation	-	ISO	Process