EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000025269 (Gene tree)
Gene ID: 77622
Gene Symbol: Apex2
Alias: Ape2|C430040P13Rik
Full Name: apurinic/apyrimidinic endonuclease 2
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 70350 bases
Position: chrX:150519519-150589868
Accession: 1924872
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000026303	Exo_endo_phos	PF03372.23	2.2e-17	1	1
ENSMUSP00000108340	Exo_endo_phos	PF03372.23	2.2e-17	1	1
ENSMUSP00000108341	Exo_endo_phos	PF03372.23	7e-16	1	1
ENSMUSP00000108339	Exo_endo_phos	PF03372.23	2.5e-13	1	1
ENSMUSP00000108345	Exo_endo_phos	PF03372.23	2.7e-13	1	1
ENSMUSP00000108347	Exo_endo_phos	PF03372.23	2.9e-13	1	1
ENSMUSP00000122554	Exo_endo_phos	PF03372.23	9.6e-13	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000140207	-	795	-	ENSMUSP00000122554	265 (aa)	-	F7CPY7
ENSMUST00000152332	-	2617	-	-	- (aa)	-	-
ENSMUST00000138958	-	784	-	-	- (aa)	-	-
ENSMUST00000124521	-	363	-	-	- (aa)	-	-
ENSMUST00000112719	-	969	XM_011247879	ENSMUSP00000108339	246 (aa)	XP_011246181	A2AFM5
ENSMUST00000026303	-	1884	XM_006528991	ENSMUSP00000026303	516 (aa)	XP_006529054	A2AFM3
ENSMUST00000112727	-	1663	-	ENSMUSP00000108347	266 (aa)	-	Q68G58
ENSMUST00000112725	-	3613	XM_011247877	ENSMUSP00000108345	260 (aa)	XP_011246179	Q68G58
ENSMUST00000112720	-	4742	-	ENSMUSP00000108340	516 (aa)	-	A2AFM3
ENSMUST00000112721	-	1852	-	ENSMUSP00000108341	523 (aa)	-	A2AFM4

Gene Model

Click here to download ENSMUSG00000025269's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03410	Base excision repair	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000025269's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000025269	Apex2	99	81.132	ENSG00000169188	APEX2	100	79.344	Homo_sapiens
ENSMUSG00000025269	Apex2	99	53.405	ENSAPOG00000005805	apex2	99	46.573	Acanthochromis_polyacanthus
ENSMUSG00000025269	Apex2	99	80.377	ENSAMEG00000003608	APEX2	100	77.563	Ailuropoda_melanoleuca
ENSMUSG00000025269	Apex2	98	53.650	ENSACIG00000010000	apex2	99	45.629	Amphilophus_citrinellus
ENSMUSG00000025269	Apex2	99	53.405	ENSAOCG00000021774	apex2	99	46.573	Amphiprion_ocellaris
ENSMUSG00000025269	Apex2	99	53.405	ENSAPEG00000020890	apex2	93	46.397	Amphiprion_percula
ENSMUSG00000025269	Apex2	99	52.669	ENSATEG00000023600	apex2	99	45.783	Anabas_testudineus
ENSMUSG00000025269	Apex2	99	58.712	ENSACAG00000011201	APEX2	99	52.132	Anolis_carolinensis
ENSMUSG00000025269	Apex2	99	80.000	ENSANAG00000021907	-	100	78.378	Aotus_nancymaae
ENSMUSG00000025269	Apex2	99	73.585	ENSANAG00000020845	-	100	69.124	Aotus_nancymaae
ENSMUSG00000025269	Apex2	98	51.087	ENSAMXG00000007422	apex2	99	45.070	Astyanax_mexicanus
ENSMUSG00000025269	Apex2	99	81.132	ENSBTAG00000013177	APEX2	100	79.497	Bos_taurus
ENSMUSG00000025269	Apex2	99	80.755	ENSCJAG00000016584	APEX2	100	78.958	Callithrix_jacchus
ENSMUSG00000025269	Apex2	99	78.113	ENSCAFG00000014310	APEX2	100	76.641	Canis_familiaris
ENSMUSG00000025269	Apex2	99	80.377	ENSCAFG00020013818	APEX2	100	77.992	Canis_lupus_dingo
ENSMUSG00000025269	Apex2	99	80.377	ENSCHIG00000019916	APEX2	100	79.110	Capra_hircus
ENSMUSG00000025269	Apex2	99	81.887	ENSTSYG00000005612	APEX2	100	78.998	Carlito_syrichta
ENSMUSG00000025269	Apex2	99	75.094	ENSCPOG00000007265	APEX2	100	73.114	Cavia_porcellus
ENSMUSG00000025269	Apex2	94	73.092	ENSCCAG00000025405	-	99	66.200	Cebus_capucinus
ENSMUSG00000025269	Apex2	99	79.245	ENSCATG00000044854	APEX2	100	78.185	Cercocebus_atys
ENSMUSG00000025269	Apex2	99	78.113	ENSCLAG00000017315	APEX2	100	75.483	Chinchilla_lanigera
ENSMUSG00000025269	Apex2	100	78.378	ENSCSAG00000012124	APEX2	100	78.378	Chlorocebus_sabaeus
ENSMUSG00000025269	Apex2	99	54.135	ENSCPBG00000016631	APEX2	99	48.256	Chrysemys_picta_bellii
ENSMUSG00000025269	Apex2	99	45.552	ENSCSAVG00000006052	-	99	39.962	Ciona_savignyi
ENSMUSG00000025269	Apex2	100	78.185	ENSCANG00000003053	APEX2	100	78.185	Colobus_angolensis_palliatus
ENSMUSG00000025269	Apex2	100	88.395	ENSCGRG00001008132	Apex2	100	88.395	Cricetulus_griseus_chok1gshd
ENSMUSG00000025269	Apex2	99	89.712	ENSCGRG00000009667	Apex2	99	89.712	Cricetulus_griseus_crigri
ENSMUSG00000025269	Apex2	99	53.986	ENSCSEG00000019900	apex2	98	45.645	Cynoglossus_semilaevis
ENSMUSG00000025269	Apex2	99	51.971	ENSCVAG00000021583	apex2	99	44.655	Cyprinodon_variegatus
ENSMUSG00000025269	Apex2	99	53.405	ENSDARG00000008472	apex2	99	45.518	Danio_rerio
ENSMUSG00000025269	Apex2	99	78.113	ENSDNOG00000038901	APEX2	100	75.676	Dasypus_novemcinctus
ENSMUSG00000025269	Apex2	94	83.983	ENSDORG00000024412	-	99	83.983	Dipodomys_ordii
ENSMUSG00000025269	Apex2	99	49.064	ENSEBUG00000015654	apex2	99	44.788	Eptatretus_burgeri
ENSMUSG00000025269	Apex2	99	81.509	ENSEASG00005011694	APEX2	91	79.537	Equus_asinus_asinus
ENSMUSG00000025269	Apex2	99	81.509	ENSECAG00000026921	APEX2	91	79.537	Equus_caballus
ENSMUSG00000025269	Apex2	99	76.604	ENSEEUG00000013172	APEX2	100	72.201	Erinaceus_europaeus
ENSMUSG00000025269	Apex2	99	53.004	ENSELUG00000021417	apex2	99	43.294	Esox_lucius
ENSMUSG00000025269	Apex2	99	78.491	ENSFCAG00000021990	APEX2	100	75.483	Felis_catus
ENSMUSG00000025269	Apex2	99	78.868	ENSFDAG00000008076	APEX2	94	84.234	Fukomys_damarensis
ENSMUSG00000025269	Apex2	99	41.993	ENSFHEG00000021411	apex2	99	42.349	Fundulus_heteroclitus
ENSMUSG00000025269	Apex2	81	55.500	ENSGMOG00000019681	apex2	89	55.779	Gadus_morhua
ENSMUSG00000025269	Apex2	99	50.903	ENSGAFG00000005829	apex2	99	45.550	Gambusia_affinis
ENSMUSG00000025269	Apex2	76	61.702	ENSGACG00000012307	apex2	81	60.417	Gasterosteus_aculeatus
ENSMUSG00000025269	Apex2	86	47.692	ENSGAGG00000011520	APEX2	85	48.098	Gopherus_agassizii
ENSMUSG00000025269	Apex2	99	80.755	ENSGGOG00000002056	APEX2	100	79.151	Gorilla_gorilla
ENSMUSG00000025269	Apex2	99	53.405	ENSHBUG00000009938	apex2	99	46.972	Haplochromis_burtoni
ENSMUSG00000025269	Apex2	99	77.736	ENSHGLG00000000273	APEX2	93	83.486	Heterocephalus_glaber_female
ENSMUSG00000025269	Apex2	86	82.629	ENSHGLG00100006734	-	100	82.629	Heterocephalus_glaber_male
ENSMUSG00000025269	Apex2	99	55.431	ENSHCOG00000010165	apex2	99	47.761	Hippocampus_comes
ENSMUSG00000025269	Apex2	84	63.285	ENSHCOG00000018521	-	100	63.285	Hippocampus_comes
ENSMUSG00000025269	Apex2	99	52.158	ENSIPUG00000000352	APEX2	99	44.501	Ictalurus_punctatus
ENSMUSG00000025269	Apex2	99	83.396	ENSSTOG00000025121	APEX2	99	83.673	Ictidomys_tridecemlineatus
ENSMUSG00000025269	Apex2	100	81.238	ENSJJAG00000019611	Apex2	100	81.238	Jaculus_jaculus
ENSMUSG00000025269	Apex2	99	56.727	ENSKMAG00000006985	apex2	99	49.376	Kryptolebias_marmoratus
ENSMUSG00000025269	Apex2	99	53.025	ENSLBEG00000012139	apex2	99	46.459	Labrus_bergylta
ENSMUSG00000025269	Apex2	99	43.816	ENSLACG00000000865	APEX2	99	43.816	Latimeria_chalumnae
ENSMUSG00000025269	Apex2	99	53.521	ENSLOCG00000014467	apex2	99	46.127	Lepisosteus_oculatus
ENSMUSG00000025269	Apex2	99	80.377	ENSLAFG00000018312	APEX2	100	77.413	Loxodonta_africana
ENSMUSG00000025269	Apex2	99	79.623	ENSMFAG00000002486	APEX2	100	78.378	Macaca_fascicularis
ENSMUSG00000025269	Apex2	99	79.623	ENSMMUG00000008428	APEX2	100	77.992	Macaca_mulatta
ENSMUSG00000025269	Apex2	99	79.623	ENSMNEG00000036783	APEX2	100	78.378	Macaca_nemestrina
ENSMUSG00000025269	Apex2	99	79.245	ENSMLEG00000028208	APEX2	100	78.185	Mandrillus_leucophaeus
ENSMUSG00000025269	Apex2	99	51.429	ENSMAMG00000024220	apex2	99	43.537	Mastacembelus_armatus
ENSMUSG00000025269	Apex2	99	53.405	ENSMZEG00005026322	apex2	99	46.972	Maylandia_zebra
ENSMUSG00000025269	Apex2	76	94.681	ENSMAUG00000016924	-	100	94.681	Mesocricetus_auratus
ENSMUSG00000025269	Apex2	100	75.290	ENSMICG00000043181	APEX2	100	75.290	Microcebus_murinus
ENSMUSG00000025269	Apex2	100	87.041	ENSMOCG00000004339	Apex2	100	88.201	Microtus_ochrogaster
ENSMUSG00000025269	Apex2	99	54.286	ENSMMOG00000017340	apex2	99	44.750	Mola_mola
ENSMUSG00000025269	Apex2	98	63.707	ENSMODG00000005341	APEX2	99	56.226	Monodelphis_domestica
ENSMUSG00000025269	Apex2	99	50.178	ENSMALG00000014179	apex2	99	44.162	Monopterus_albus
ENSMUSG00000025269	Apex2	100	98.780	MGP_CAROLIEiJ_G0033484	Apex2	100	99.621	Mus_caroli
ENSMUSG00000025269	Apex2	100	97.132	MGP_PahariEiJ_G0032023	Apex2	100	98.106	Mus_pahari
ENSMUSG00000025269	Apex2	100	99.235	MGP_SPRETEiJ_G0034654	Apex2	100	99.621	Mus_spretus
ENSMUSG00000025269	Apex2	99	79.245	ENSMPUG00000003293	APEX2	100	76.789	Mustela_putorius_furo
ENSMUSG00000025269	Apex2	99	77.736	ENSMLUG00000016298	-	100	74.517	Myotis_lucifugus
ENSMUSG00000025269	Apex2	99	76.226	ENSMLUG00000004562	-	100	72.587	Myotis_lucifugus
ENSMUSG00000025269	Apex2	99	83.712	ENSNGAG00000013576	Apex2	100	82.205	Nannospalax_galili
ENSMUSG00000025269	Apex2	99	53.405	ENSNBRG00000010099	apex2	99	45.486	Neolamprologus_brichardi
ENSMUSG00000025269	Apex2	98	80.843	ENSNLEG00000032067	-	100	81.955	Nomascus_leucogenys
ENSMUSG00000025269	Apex2	86	83.568	ENSODEG00000003095	-	100	83.568	Octodon_degus
ENSMUSG00000025269	Apex2	99	55.849	ENSONIG00000016881	apex2	99	49.248	Oreochromis_niloticus
ENSMUSG00000025269	Apex2	77	66.977	ENSOANG00000000689	-	95	52.784	Ornithorhynchus_anatinus
ENSMUSG00000025269	Apex2	86	85.446	ENSOCUG00000000570	APEX2	100	66.089	Oryctolagus_cuniculus
ENSMUSG00000025269	Apex2	99	53.650	ENSORLG00000014053	apex2	99	47.500	Oryzias_latipes
ENSMUSG00000025269	Apex2	99	52.190	ENSORLG00020013253	apex2	99	46.607	Oryzias_latipes_hni
ENSMUSG00000025269	Apex2	98	54.275	ENSORLG00015007515	apex2	99	47.500	Oryzias_latipes_hsok
ENSMUSG00000025269	Apex2	99	52.518	ENSOMEG00000003655	apex2	99	45.714	Oryzias_melastigma
ENSMUSG00000025269	Apex2	99	78.491	ENSOGAG00000007797	APEX2	99	77.626	Otolemur_garnettii
ENSMUSG00000025269	Apex2	99	80.755	ENSOARG00000005742	APEX2	100	79.304	Ovis_aries
ENSMUSG00000025269	Apex2	99	80.000	ENSPPAG00000035747	APEX2	100	78.958	Pan_paniscus
ENSMUSG00000025269	Apex2	99	78.868	ENSPPRG00000002440	APEX2	100	75.483	Panthera_pardus
ENSMUSG00000025269	Apex2	99	78.113	ENSPTIG00000021651	APEX2	100	75.097	Panthera_tigris_altaica
ENSMUSG00000025269	Apex2	99	80.377	ENSPTRG00000021946	APEX2	100	79.151	Pan_troglodytes
ENSMUSG00000025269	Apex2	99	79.623	ENSPANG00000003595	APEX2	100	78.378	Papio_anubis
ENSMUSG00000025269	Apex2	99	51.418	ENSPKIG00000007752	apex2	99	45.775	Paramormyrops_kingsleyae
ENSMUSG00000025269	Apex2	99	50.714	ENSPMGG00000009151	apex2	99	44.128	Periophthalmus_magnuspinnatus
ENSMUSG00000025269	Apex2	100	88.201	ENSPEMG00000016475	Apex2	100	88.571	Peromyscus_maniculatus_bairdii
ENSMUSG00000025269	Apex2	98	61.303	ENSPCIG00000007633	APEX2	98	55.859	Phascolarctos_cinereus
ENSMUSG00000025269	Apex2	99	51.986	ENSPFOG00000000408	apex2	99	45.550	Poecilia_formosa
ENSMUSG00000025269	Apex2	99	51.986	ENSPLAG00000023814	apex2	99	45.550	Poecilia_latipinna
ENSMUSG00000025269	Apex2	99	51.625	ENSPMEG00000023222	apex2	99	45.375	Poecilia_mexicana
ENSMUSG00000025269	Apex2	99	80.755	ENSPPYG00000020388	APEX2	100	79.151	Pongo_abelii
ENSMUSG00000025269	Apex2	99	79.623	ENSPCOG00000016083	APEX2	100	77.799	Propithecus_coquereli
ENSMUSG00000025269	Apex2	90	77.634	ENSPVAG00000007851	APEX2	100	77.634	Pteropus_vampyrus
ENSMUSG00000025269	Apex2	99	53.047	ENSPNYG00000015698	apex2	99	45.694	Pundamilia_nyererei
ENSMUSG00000025269	Apex2	99	53.430	ENSPNAG00000011666	apex2	99	44.595	Pygocentrus_nattereri
ENSMUSG00000025269	Apex2	100	92.636	ENSRNOG00000000166	Apex2	100	92.636	Rattus_norvegicus
ENSMUSG00000025269	Apex2	100	78.764	ENSRBIG00000036500	APEX2	100	78.764	Rhinopithecus_bieti
ENSMUSG00000025269	Apex2	99	79.623	ENSRROG00000032674	APEX2	100	78.571	Rhinopithecus_roxellana
ENSMUSG00000025269	Apex2	99	80.377	ENSSBOG00000030500	-	100	78.571	Saimiri_boliviensis_boliviensis
ENSMUSG00000025269	Apex2	96	62.926	ENSSBOG00000003489	-	99	62.926	Saimiri_boliviensis_boliviensis
ENSMUSG00000025269	Apex2	98	62.835	ENSSHAG00000007846	APEX2	99	55.166	Sarcophilus_harrisii
ENSMUSG00000025269	Apex2	99	54.093	ENSSFOG00015010354	apex2	99	48.624	Scleropages_formosus
ENSMUSG00000025269	Apex2	99	51.418	ENSSMAG00000012753	apex2	99	45.217	Scophthalmus_maximus
ENSMUSG00000025269	Apex2	99	51.601	ENSSDUG00000022892	apex2	99	46.004	Seriola_dumerili
ENSMUSG00000025269	Apex2	99	51.601	ENSSLDG00000024347	apex2	99	46.630	Seriola_lalandi_dorsalis
ENSMUSG00000025269	Apex2	99	75.940	ENSSARG00000010297	APEX2	100	71.209	Sorex_araneus
ENSMUSG00000025269	Apex2	87	53.991	ENSSPUG00000019279	-	88	53.991	Sphenodon_punctatus
ENSMUSG00000025269	Apex2	99	52.688	ENSSPAG00000016279	apex2	99	46.853	Stegastes_partitus
ENSMUSG00000025269	Apex2	99	80.000	ENSSSCG00000012348	-	100	78.185	Sus_scrofa
ENSMUSG00000025269	Apex2	99	52.330	ENSTRUG00000015660	apex2	99	46.737	Takifugu_rubripes
ENSMUSG00000025269	Apex2	81	47.045	ENSTNIG00000003725	apex2	100	47.045	Tetraodon_nigroviridis
ENSMUSG00000025269	Apex2	90	77.419	ENSTBEG00000010520	APEX2	100	77.419	Tupaia_belangeri
ENSMUSG00000025269	Apex2	99	80.377	ENSUAMG00000004720	APEX2	100	77.950	Ursus_americanus
ENSMUSG00000025269	Apex2	100	73.114	ENSUMAG00000002892	APEX2	100	73.114	Ursus_maritimus
ENSMUSG00000025269	Apex2	99	80.000	ENSVVUG00000005989	APEX2	100	77.606	Vulpes_vulpes
ENSMUSG00000025269	Apex2	99	53.818	ENSXETG00000022026	apex2	98	49.245	Xenopus_tropicalis
ENSMUSG00000025269	Apex2	90	58.559	ENSXCOG00000014274	apex2	100	58.559	Xiphophorus_couchianus
ENSMUSG00000025269	Apex2	99	52.364	ENSXMAG00000025740	apex2	99	45.534	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001650	fibrillar center	-	ISO	Component
GO:0003677	DNA binding	-	IEA	Function
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	21873635.	IBA	Function
GO:0004518	nuclease activity	-	IEA	Function
GO:0004519	endonuclease activity	-	IEA	Function
GO:0004527	exonuclease activity	-	IEA	Function
GO:0004528	phosphodiesterase I activity	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	12573260.	IDA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0005739	mitochondrion	14651853.18614015.	HDA	Component
GO:0005743	mitochondrial inner membrane	12573260.	IDA	Component
GO:0006281	DNA repair	-	IEA	Process
GO:0006284	base-excision repair	21873635.	IBA	Process
GO:0006310	DNA recombination	-	IEA	Process
GO:0006974	cellular response to DNA damage stimulus	-	IEA	Process
GO:0007049	cell cycle	-	IEA	Process
GO:0008270	zinc ion binding	-	IEA	Function
GO:0008311	double-stranded DNA 3'-5' exodeoxyribonuclease activity	21873635.	IBA	Function
GO:0016787	hydrolase activity	-	IEA	Function
GO:0016829	lyase activity	-	IEA	Function
GO:0043231	intracellular membrane-bounded organelle	-	ISO	Component
GO:0046872	metal ion binding	-	IEA	Function