EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000025403 (Gene tree)
Gene ID: 108037
Gene Symbol: Shmt2
Alias: 2700043D08Rik
Full Name: serine hydroxymethyltransferase 2 (mitochondrial)
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 5322
Position: chr10: 127517123-127522444
Accession: 1277989
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000218035	-	722	-	-	- (aa)	-	-
ENSMUST00000220356	-	754	-	-	- (aa)	-	-
ENSMUST00000218258	-	960	-	-	- (aa)	-	-
ENSMUST00000026470	-	2289	-	ENSMUSP00000026470	504 (aa)	-	Q9CZN7
ENSMUST00000219239	-	2238	-	ENSMUSP00000151616	501 (aa)	-	Q9CZN7
ENSMUST00000217682	-	725	-	-	- (aa)	-	-
ENSMUST00000218313	-	397	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000025403's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu00260	Glycine, serine and threonine metabolism	KEGG
mmu00630	Glyoxylate and dicarboxylate metabolism	KEGG
mmu00670	One carbon pool by folate	KEGG
mmu01100	Metabolic pathways	KEGG
mmu01200	Carbon metabolism	KEGG
mmu01230	Biosynthesis of amino acids	KEGG
mmu01523	Antifolate resistance	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000025403's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000025403	Shmt2	91	59.913	FBgn0029823	Shmt	98	59.913	Drosophila_melanogaster
ENSMUSG00000025403	Shmt2	99	94.036	ENSG00000182199	SHMT2	100	95.814	Homo_sapiens
ENSMUSG00000025403	Shmt2	90	55.947	YLR058C	SHM2	96	55.947	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002082	regulation of oxidative phosphorylation	21873635.	IBA	Process
GO:0002082	regulation of oxidative phosphorylation	29323231.	IMP	Process
GO:0002082	regulation of oxidative phosphorylation	-	ISO	Process
GO:0003682	chromatin binding	-	ISO	Function
GO:0003824	catalytic activity	-	IEA	Function
GO:0004372	glycine hydroxymethyltransferase activity	21873635.	IBA	Function
GO:0004372	glycine hydroxymethyltransferase activity	-	ISO	Function
GO:0005634	nucleus	-	ISO	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005739	mitochondrion	14651853.18614015.	HDA	Component
GO:0005739	mitochondrion	21873635.	IBA	Component
GO:0005739	mitochondrion	-	ISO	Component
GO:0005743	mitochondrial inner membrane	12865426.	HDA	Component
GO:0005743	mitochondrial inner membrane	21873635.	IBA	Component
GO:0005743	mitochondrial inner membrane	-	ISO	Component
GO:0005758	mitochondrial intermembrane space	-	ISO	Component
GO:0005759	mitochondrial matrix	21873635.	IBA	Component
GO:0005759	mitochondrial matrix	-	ISO	Component
GO:0006544	glycine metabolic process	21873635.	IBA	Process
GO:0006544	glycine metabolic process	-	ISO	Process
GO:0006545	glycine biosynthetic process	-	ISO	Process
GO:0006563	L-serine metabolic process	-	ISO	Process
GO:0006564	L-serine biosynthetic process	-	ISO	Process
GO:0006565	L-serine catabolic process	21873635.	IBA	Process
GO:0006730	one-carbon metabolic process	21873635.	IBA	Process
GO:0006730	one-carbon metabolic process	-	ISO	Process
GO:0008270	zinc ion binding	21873635.	IBA	Function
GO:0008284	positive regulation of cell proliferation	-	ISO	Process
GO:0008732	L-allo-threonine aldolase activity	-	ISO	Function
GO:0015630	microtubule cytoskeleton	-	ISO	Component
GO:0016020	membrane	-	IEA	Component
GO:0016597	amino acid binding	21873635.	IBA	Function
GO:0016597	amino acid binding	-	ISO	Function
GO:0016740	transferase activity	-	IEA	Function
GO:0019264	glycine biosynthetic process from serine	21873635.	IBA	Process
GO:0019264	glycine biosynthetic process from serine	-	ISO	Process
GO:0030170	pyridoxal phosphate binding	21873635.	IBA	Function
GO:0030170	pyridoxal phosphate binding	-	ISO	Function
GO:0034340	response to type I interferon	21873635.	IBA	Process
GO:0034340	response to type I interferon	-	ISO	Process
GO:0035999	tetrahydrofolate interconversion	-	IEA	Process
GO:0042645	mitochondrial nucleoid	-	ISO	Component
GO:0042802	identical protein binding	21873635.	IBA	Function
GO:0042802	identical protein binding	-	ISO	Function
GO:0046653	tetrahydrofolate metabolic process	21873635.	IBA	Process
GO:0046653	tetrahydrofolate metabolic process	-	ISO	Process
GO:0046655	folic acid metabolic process	21873635.	IBA	Process
GO:0050897	cobalt ion binding	21873635.	IBA	Function
GO:0051262	protein tetramerization	-	ISO	Process
GO:0051289	protein homotetramerization	21873635.	IBA	Process
GO:0051289	protein homotetramerization	-	ISO	Process
GO:0070129	regulation of mitochondrial translation	29323231.29452640.	IMP	Process
GO:0070129	regulation of mitochondrial translation	-	ISO	Process
GO:0070536	protein K63-linked deubiquitination	-	ISO	Process
GO:0070552	BRISC complex	21873635.	IBA	Component
GO:0070552	BRISC complex	-	ISO	Component
GO:0070905	serine binding	21873635.	IBA	Function
GO:1903715	regulation of aerobic respiration	29323231.	IMP	Process
GO:1903715	regulation of aerobic respiration	-	ISO	Process
GO:1904482	cellular response to tetrahydrofolate	21873635.	IBA	Process