EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000025809 (Gene tree)
Gene ID: 16412
Gene Symbol: Itgb1
Alias: 4633401G24Rik|CD29|Fnrb|Gm9863|beta1 integrin
Full Name: integrin beta 1 (fibronectin receptor beta)
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 47547
Position: chr8: 128685654-128733200
Accession: 96610
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000124826	-	2906	-	ENSMUSP00000120026	58 (aa)	-	D6RJL5
ENSMUST00000149116	-	711	-	ENSMUSP00000119699	112 (aa)	-	A0A0A0MQJ3
ENSMUST00000090006	-	3815	-	ENSMUSP00000087457	798 (aa)	-	P09055
ENSMUST00000135281	-	651	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000025809's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04015	Rap1 signaling pathway	KEGG
mmu04145	Phagosome	KEGG
mmu04151	PI3K-Akt signaling pathway	KEGG
mmu04360	Axon guidance	KEGG
mmu04510	Focal adhesion	KEGG
mmu04512	ECM-receptor interaction	KEGG
mmu04514	Cell adhesion molecules (CAMs)	KEGG
mmu04530	Tight junction	KEGG
mmu04611	Platelet activation	KEGG
mmu04670	Leukocyte transendothelial migration	KEGG
mmu04810	Regulation of actin cytoskeleton	KEGG
mmu05100	Bacterial invasion of epithelial cells	KEGG
mmu05133	Pertussis	KEGG
mmu05140	Leishmaniasis	KEGG
mmu05145	Toxoplasmosis	KEGG
mmu05165	Human papillomavirus infection	KEGG
mmu05200	Pathways in cancer	KEGG
mmu05205	Proteoglycans in cancer	KEGG
mmu05222	Small cell lung cancer	KEGG
mmu05410	Hypertrophic cardiomyopathy (HCM)	KEGG
mmu05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	KEGG
mmu05414	Dilated cardiomyopathy (DCM)	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000025809's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000025809	Itgb1	99	95.495	ENSG00000150093	ITGB1	99	100.000	Homo_sapiens
ENSMUSG00000025809	Itgb1	96	46.512	ENSMUSG00000000290	Itgb2	97	48.665	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000082	G1/S transition of mitotic cell cycle	12957148.	IMP	Process
GO:0001669	acrosomal vesicle	-	ISO	Component
GO:0001701	in utero embryonic development	7544313.	IMP	Process
GO:0001708	cell fate specification	9004034.	IMP	Process
GO:0001894	tissue homeostasis	-	ISO	Process
GO:0001968	fibronectin binding	21873635.	IBA	Function
GO:0001968	fibronectin binding	-	ISO	Function
GO:0002020	protease binding	-	ISO	Function
GO:0002042	cell migration involved in sprouting angiogenesis	16424942.	IMP	Process
GO:0003779	actin binding	-	ISO	Function
GO:0005102	signaling receptor binding	-	ISO	Function
GO:0005178	integrin binding	21873635.	IBA	Function
GO:0005178	integrin binding	1833411.8601592.	IPI	Function
GO:0005178	integrin binding	-	ISO	Function
GO:0005515	protein binding	10613898.10634791.11223950.12189152.12904471.15102471.15723043.17377534.18278053.18794329.20802515.21427700.22357865.23395392.	IPI	Function
GO:0005518	collagen binding	-	ISO	Function
GO:0005604	basement membrane	-	ISO	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005768	endosome	-	IEA	Component
GO:0005886	plasma membrane	12591243.12670870.14522949.	IDA	Component
GO:0005886	plasma membrane	12189152.	IDA	Component
GO:0005886	plasma membrane	-	ISO	Component
GO:0005911	cell-cell junction	-	ISO	Component
GO:0005912	adherens junction	-	ISO	Component
GO:0005925	focal adhesion	21873635.	IBA	Component
GO:0005925	focal adhesion	29162887.	ISO	Component
GO:0006909	phagocytosis	-	ISO	Process
GO:0007155	cell adhesion	-	ISO	Process
GO:0007159	leukocyte cell-cell adhesion	-	ISO	Process
GO:0007160	cell-matrix adhesion	21873635.	IBA	Process
GO:0007160	cell-matrix adhesion	17099249.	IGI	Process
GO:0007160	cell-matrix adhesion	21185282.	IMP	Process
GO:0007160	cell-matrix adhesion	-	ISO	Process
GO:0007161	calcium-independent cell-matrix adhesion	-	ISO	Process
GO:0007179	transforming growth factor beta receptor signaling pathway	24036928.	IMP	Process
GO:0007229	integrin-mediated signaling pathway	21873635.	IBA	Process
GO:0007229	integrin-mediated signaling pathway	-	ISO	Process
GO:0008277	regulation of G protein-coupled receptor signaling pathway	-	ISO	Process
GO:0008284	positive regulation of cell proliferation	15056720.	IMP	Process
GO:0008285	negative regulation of cell proliferation	-	ISO	Process
GO:0008305	integrin complex	21873635.	IBA	Component
GO:0008305	integrin complex	-	ISO	Component
GO:0008354	germ cell migration	10079228.	IMP	Process
GO:0008542	visual learning	22357865.	IGI	Process
GO:0008542	visual learning	22357865.	IMP	Process
GO:0009897	external side of plasma membrane	9553049.19487454.20103531.	IDA	Component
GO:0009986	cell surface	21873635.	IBA	Component
GO:0009986	cell surface	8306881.23023225.	IDA	Component
GO:0009986	cell surface	23620790.	ISO	Component
GO:0010710	regulation of collagen catabolic process	-	ISO	Process
GO:0010811	positive regulation of cell-substrate adhesion	-	ISO	Process
GO:0010976	positive regulation of neuron projection development	-	ISO	Process
GO:0014704	intercalated disc	11732910.	IDA	Component
GO:0016020	membrane	23395392.	IDA	Component
GO:0016020	membrane	-	ISO	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0016477	cell migration	21873635.	IBA	Process
GO:0016477	cell migration	9553049.	IMP	Process
GO:0019900	kinase binding	-	ISO	Function
GO:0019901	protein kinase binding	-	ISO	Function
GO:0019904	protein domain specific binding	-	ISO	Function
GO:0019960	C-X3-C chemokine binding	21873635.	IBA	Function
GO:0019960	C-X3-C chemokine binding	-	ISO	Function
GO:0021943	formation of radial glial scaffolds	21185282.	IMP	Process
GO:0030030	cell projection organization	-	ISO	Process
GO:0030032	lamellipodium assembly	-	ISO	Process
GO:0030054	cell junction	-	IEA	Component
GO:0030056	hemidesmosome	-	ISO	Component
GO:0030175	filopodium	-	ISO	Component
GO:0030335	positive regulation of cell migration	-	ISO	Process
GO:0031175	neuron projection development	19118221.	IMP	Process
GO:0031345	negative regulation of cell projection organization	-	ISO	Process
GO:0031410	cytoplasmic vesicle	12189152.	IDA	Component
GO:0031589	cell-substrate adhesion	-	ISO	Process
GO:0031594	neuromuscular junction	9415431.	IDA	Component
GO:0031594	neuromuscular junction	-	ISO	Component
GO:0031623	receptor internalization	23395392.	IDA	Process
GO:0032587	ruffle membrane	-	ISO	Component
GO:0032594	protein transport within lipid bilayer	-	ISO	Process
GO:0033627	cell adhesion mediated by integrin	21873635.	IBA	Process
GO:0033627	cell adhesion mediated by integrin	-	ISO	Process
GO:0034113	heterotypic cell-cell adhesion	-	ISO	Process
GO:0034665	integrin alpha1-beta1 complex	-	ISO	Component
GO:0034666	integrin alpha2-beta1 complex	-	ISO	Component
GO:0034667	integrin alpha3-beta1 complex	-	ISO	Component
GO:0034677	integrin alpha7-beta1 complex	18611855.	IDA	Component
GO:0034677	integrin alpha7-beta1 complex	1839357.	IPI	Component
GO:0034679	integrin alpha9-beta1 complex	-	ISO	Component
GO:0034680	integrin alpha10-beta1 complex	-	ISO	Component
GO:0034681	integrin alpha11-beta1 complex	-	ISO	Component
GO:0035024	negative regulation of Rho protein signal transduction	22357865.	IGI	Process
GO:0035748	myelin sheath abaxonal region	20237282.	IDA	Component
GO:0038023	signaling receptor activity	-	IEA	Function
GO:0042383	sarcolemma	9415431.	IDA	Component
GO:0042383	sarcolemma	-	ISO	Component
GO:0042995	cell projection	-	IEA	Component
GO:0043065	positive regulation of apoptotic process	-	ISO	Process
GO:0043066	negative regulation of apoptotic process	-	ISO	Process
GO:0043149	stress fiber assembly	24036928.	IMP	Process
GO:0043197	dendritic spine	22357865.	IDA	Component
GO:0043197	dendritic spine	-	ISO	Component
GO:0043235	receptor complex	23382219.	ISO	Component
GO:0043236	laminin binding	21873635.	IBA	Function
GO:0043236	laminin binding	1839357.	IDA	Function
GO:0043236	laminin binding	-	ISO	Function
GO:0043547	positive regulation of GTPase activity	-	ISO	Process
GO:0044877	protein-containing complex binding	-	ISO	Function
GO:0045121	membrane raft	-	ISO	Component
GO:0045202	synapse	12904471.	IDA	Component
GO:0045211	postsynaptic membrane	-	ISO	Component
GO:0045214	sarcomere organization	9004034.	IMP	Process
GO:0045596	negative regulation of cell differentiation	15056720.	IMP	Process
GO:0045665	negative regulation of neuron differentiation	-	ISO	Process
GO:0045666	positive regulation of neuron differentiation	-	ISO	Process
GO:0045766	positive regulation of angiogenesis	-	ISO	Process
GO:0045807	positive regulation of endocytosis	-	ISO	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0046982	protein heterodimerization activity	-	ISO	Function
GO:0048471	perinuclear region of cytoplasm	12189152.	IDA	Component
GO:0048471	perinuclear region of cytoplasm	-	ISO	Component
GO:0048675	axon extension	12879062.	IGI	Process
GO:0048675	axon extension	12879062.	IMP	Process
GO:0048738	cardiac muscle tissue development	9553049.	IMP	Process
GO:0048813	dendrite morphogenesis	22357865.	IGI	Process
GO:0048813	dendrite morphogenesis	22357865.	IMP	Process
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	-	ISO	Process
GO:0050804	modulation of chemical synaptic transmission	17065460.	IMP	Process
GO:0050839	cell adhesion molecule binding	-	ISO	Function
GO:0050901	leukocyte tethering or rolling	-	ISO	Process
GO:0051393	alpha-actinin binding	-	ISO	Function
GO:0051726	regulation of cell cycle	14522949.	IMP	Process
GO:0051897	positive regulation of protein kinase B signaling	-	ISO	Process
GO:0055007	cardiac muscle cell differentiation	9004034.	IMP	Process
GO:0070830	bicellular tight junction assembly	-	ISO	Process
GO:0071404	cellular response to low-density lipoprotein particle stimulus	23395392.	IDA	Process
GO:0071438	invadopodium membrane	-	ISO	Component
GO:0071711	basement membrane organization	24681597.	IMP	Process
GO:0097060	synaptic membrane	22357865.	IDA	Component
GO:0097386	glial cell projection	-	ISO	Component
GO:0098639	collagen binding involved in cell-matrix adhesion	21873635.	IBA	Function
GO:0098639	collagen binding involved in cell-matrix adhesion	-	ISO	Function
GO:0098685	Schaffer collateral - CA1 synapse	17065460.	IMP	Component
GO:0098978	glutamatergic synapse	16467530.	IDA	Component
GO:0098978	glutamatergic synapse	-	ISO	Component
GO:0099055	integral component of postsynaptic membrane	-	ISO	Component
GO:0099699	integral component of synaptic membrane	16467530.	IDA	Component
GO:1903078	positive regulation of protein localization to plasma membrane	-	ISO	Process
GO:2000273	positive regulation of signaling receptor activity	-	ISO	Process
GO:2000811	negative regulation of anoikis	-	ISO	Process