EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000025889 (Gene tree)
Gene ID: 20617
Gene Symbol: Snca
Alias: alpha-Syn|alpha-synuclein|alphaSYN
Full Name: synuclein%2C alpha
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 98281
Position: chr6: 60731575-60829855
Accession: 1277151
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000203177	-	1407	-	-	- (aa)	-	-
ENSMUST00000163779	-	1188	-	ENSMUSP00000126067	140 (aa)	-	O55042
ENSMUST00000114268	-	1280	-	ENSMUSP00000109907	140 (aa)	-	O55042
ENSMUST00000204586	-	569	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000025889's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu05010	Alzheimer disease	KEGG
mmu05012	Parkinson disease	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000025889's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000025889	Snca	71	67.000	ENSMUSG00000023064	Sncg	81	67.000	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000149	SNARE binding	-	ISO	Function
GO:0000287	magnesium ion binding	-	ISO	Function
GO:0001774	microglial cell activation	17035541.	IMP	Process
GO:0001921	positive regulation of receptor recycling	-	ISO	Process
GO:0001933	negative regulation of protein phosphorylation	-	ISO	Process
GO:0001956	positive regulation of neurotransmitter secretion	15510220.	IDA	Process
GO:0001963	synaptic transmission, dopaminergic	10707987.12388586.	IMP	Process
GO:0003779	actin binding	-	ISO	Function
GO:0005507	copper ion binding	-	ISO	Function
GO:0005509	calcium ion binding	-	ISO	Function
GO:0005515	protein binding	22163275.24983211.	IPI	Function
GO:0005543	phospholipid binding	-	ISO	Function
GO:0005576	extracellular region	-	ISO	Component
GO:0005615	extracellular space	-	ISO	Component
GO:0005634	nucleus	16959795.	IDA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005640	nuclear outer membrane	-	ISO	Component
GO:0005737	cytoplasm	17475220.20457918.	IDA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005739	mitochondrion	-	ISO	Component
GO:0005741	mitochondrial outer membrane	-	ISO	Component
GO:0005743	mitochondrial inner membrane	-	ISO	Component
GO:0005758	mitochondrial intermembrane space	-	ISO	Component
GO:0005759	mitochondrial matrix	-	ISO	Component
GO:0005791	rough endoplasmic reticulum	-	ISO	Component
GO:0005794	Golgi apparatus	-	ISO	Component
GO:0005829	cytosol	18980610.	IDA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005840	ribosome	-	ISO	Component
GO:0005856	cytoskeleton	17077307.	IDA	Component
GO:0005886	plasma membrane	17475220.25246573.	IDA	Component
GO:0005886	plasma membrane	-	ISO	Component
GO:0005938	cell cortex	-	ISO	Component
GO:0006631	fatty acid metabolic process	14507911.17250686.	IMP	Process
GO:0006638	neutral lipid metabolic process	17250686.	IMP	Process
GO:0006644	phospholipid metabolic process	15938614.16260631.16734431.	IMP	Process
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	-	ISO	Process
GO:0007006	mitochondrial membrane organization	16260631.	IMP	Process
GO:0007268	chemical synaptic transmission	20974939.	IGI	Process
GO:0008017	microtubule binding	-	ISO	Function
GO:0008021	synaptic vesicle	-	ISO	Component
GO:0008198	ferrous iron binding	-	ISO	Function
GO:0008270	zinc ion binding	-	ISO	Function
GO:0008344	adult locomotory behavior	18333965.	IGI	Process
GO:0010040	response to iron(II) ion	-	ISO	Process
GO:0010517	regulation of phospholipase activity	-	ISO	Process
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	-	ISO	Process
GO:0014048	regulation of glutamate secretion	17689254.	IMP	Process
GO:0014059	regulation of dopamine secretion	18333965.	IGI	Process
GO:0014059	regulation of dopamine secretion	21563316.	TAS	Process
GO:0015629	actin cytoskeleton	-	ISO	Component
GO:0016020	membrane	-	ISO	Component
GO:0016079	synaptic vesicle exocytosis	-	ISO	Process
GO:0016234	inclusion body	17222866.24076025.	IDA	Component
GO:0016234	inclusion body	-	ISO	Component
GO:0016491	oxidoreductase activity	-	ISO	Function
GO:0019894	kinesin binding	-	ISO	Function
GO:0019899	enzyme binding	-	ISO	Function
GO:0019904	protein domain specific binding	-	ISO	Function
GO:0022898	regulation of transmembrane transporter activity	-	ISO	Process
GO:0030054	cell junction	-	IEA	Component
GO:0030424	axon	-	ISO	Component
GO:0030426	growth cone	-	ISO	Component
GO:0030544	Hsp70 protein binding	-	ISO	Function
GO:0030659	cytoplasmic vesicle membrane	-	ISO	Component
GO:0030672	synaptic vesicle membrane	28052246.	IDA	Component
GO:0031092	platelet alpha granule membrane	-	ISO	Component
GO:0031115	negative regulation of microtubule polymerization	-	ISO	Process
GO:0031623	receptor internalization	-	ISO	Process
GO:0031648	protein destabilization	-	ISO	Process
GO:0032026	response to magnesium ion	-	ISO	Process
GO:0032410	negative regulation of transporter activity	-	ISO	Process
GO:0032496	response to lipopolysaccharide	-	ISO	Process
GO:0032769	negative regulation of monooxygenase activity	-	ISO	Process
GO:0033138	positive regulation of peptidyl-serine phosphorylation	21127069.	IMP	Process
GO:0034341	response to interferon-gamma	-	ISO	Process
GO:0034599	cellular response to oxidative stress	16298531.	IMP	Process
GO:0035067	negative regulation of histone acetylation	-	ISO	Process
GO:0035493	SNARE complex assembly	25246573.	IDA	Process
GO:0035493	SNARE complex assembly	-	ISO	Process
GO:0040012	regulation of locomotion	10707987.	IMP	Process
GO:0042393	histone binding	16959795.	IDA	Function
GO:0042393	histone binding	-	ISO	Function
GO:0042416	dopamine biosynthetic process	10707987.	IMP	Process
GO:0042417	dopamine metabolic process	15465911.	IGI	Process
GO:0042493	response to drug	10707987.	IMP	Process
GO:0042775	mitochondrial ATP synthesis coupled electron transport	16260631.	IMP	Process
GO:0042802	identical protein binding	10978144.	IDA	Function
GO:0042802	identical protein binding	-	ISO	Function
GO:0043014	alpha-tubulin binding	-	ISO	Function
GO:0043025	neuronal cell body	26203154.	IMP	Component
GO:0043025	neuronal cell body	-	ISO	Component
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	-	ISO	Function
GO:0043030	regulation of macrophage activation	17035541.	IMP	Process
GO:0043066	negative regulation of apoptotic process	-	ISO	Process
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	-	ISO	Process
GO:0043195	terminal bouton	-	ISO	Component
GO:0043231	intracellular membrane-bounded organelle	-	ISO	Component
GO:0043274	phospholipase binding	-	ISO	Function
GO:0043523	regulation of neuron apoptotic process	15380020.	IMP	Process
GO:0043524	negative regulation of neuron apoptotic process	16269331.	IGI	Process
GO:0043524	negative regulation of neuron apoptotic process	-	ISO	Process
GO:0043679	axon terminus	-	ISO	Component
GO:0045202	synapse	10964942.	IDA	Component
GO:0045807	positive regulation of endocytosis	-	ISO	Process
GO:0045920	negative regulation of exocytosis	-	ISO	Process
GO:0045921	positive regulation of exocytosis	-	ISO	Process
GO:0045963	negative regulation of dopamine metabolic process	-	ISO	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0046928	regulation of neurotransmitter secretion	18333965.	IGI	Process
GO:0046928	regulation of neurotransmitter secretion	10707987.12388586.15510220.	IMP	Process
GO:0047485	protein N-terminus binding	-	ISO	Function
GO:0048148	behavioral response to cocaine	-	ISO	Process
GO:0048156	tau protein binding	-	ISO	Function
GO:0048168	regulation of neuronal synaptic plasticity	17610578.	IMP	Process
GO:0048169	regulation of long-term neuronal synaptic plasticity	15510220.	IMP	Process
GO:0048471	perinuclear region of cytoplasm	-	ISO	Component
GO:0048487	beta-tubulin binding	-	ISO	Function
GO:0048488	synaptic vesicle endocytosis	25009269.	EXP	Process
GO:0048488	synaptic vesicle endocytosis	25009269.	IDA	Process
GO:0048488	synaptic vesicle endocytosis	18980610.25009269.	IMP	Process
GO:0048489	synaptic vesicle transport	12388586.	IMP	Process
GO:0050544	arachidonic acid binding	16734431.	IDA	Function
GO:0050729	positive regulation of inflammatory response	-	ISO	Process
GO:0050806	positive regulation of synaptic transmission	15579163.	IMP	Process
GO:0050808	synapse organization	20974939.	IGI	Process
GO:0050812	regulation of acyl-CoA biosynthetic process	16734431.	IDA	Process
GO:0050812	regulation of acyl-CoA biosynthetic process	16636270.	IMP	Process
GO:0051219	phosphoprotein binding	-	ISO	Function
GO:0051259	protein complex oligomerization	25246573.	IDA	Process
GO:0051262	protein tetramerization	-	ISO	Process
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	-	ISO	Process
GO:0051585	negative regulation of dopamine uptake involved in synaptic transmission	-	ISO	Process
GO:0051612	negative regulation of serotonin uptake	-	ISO	Process
GO:0051621	regulation of norepinephrine uptake	-	ISO	Process
GO:0051622	negative regulation of norepinephrine uptake	-	ISO	Process
GO:0055114	oxidation-reduction process	-	ISO	Process
GO:0060079	excitatory postsynaptic potential	17610578.	IMP	Process
GO:0060291	long-term synaptic potentiation	17689254.	IMP	Process
GO:0060732	positive regulation of inositol phosphate biosynthetic process	-	ISO	Process
GO:0061024	membrane organization	14507911.	IMP	Process
GO:0070495	negative regulation of thrombin-activated receptor signaling pathway	-	ISO	Process
GO:0070555	response to interleukin-1	-	ISO	Process
GO:0070840	dynein complex binding	-	ISO	Function
GO:0071280	cellular response to copper ion	-	ISO	Process
GO:0071902	positive regulation of protein serine/threonine kinase activity	-	ISO	Process
GO:0098793	presynapse	-	ISO	Component
GO:0099512	supramolecular fiber	-	ISO	Component
GO:1901214	regulation of neuron death	-	ISO	Process
GO:1901215	negative regulation of neuron death	-	ISO	Process
GO:1901216	positive regulation of neuron death	-	ISO	Process
GO:1903136	cuprous ion binding	-	ISO	Function
GO:1903284	positive regulation of glutathione peroxidase activity	-	ISO	Process
GO:1903285	positive regulation of hydrogen peroxide catabolic process	-	ISO	Process
GO:1904715	negative regulation of chaperone-mediated autophagy	-	ISO	Process
GO:1905606	regulation of presynapse assembly	-	ISO	Process
GO:2000377	regulation of reactive oxygen species metabolic process	25043722.	IMP	Process