EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000025980 (Gene tree)
Gene ID: 15510
Gene Symbol: Hspd1
Alias: Hsp60
Full Name: heat shock protein 1 (chaperonin)
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 10409
Position: chr1: 55077835-55088243
Accession: 96242
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000027123	-	2423	XM_006495706	ENSMUSP00000027123	573 (aa)	XP_006495769	P63038
ENSMUST00000144077	-	528	-	ENSMUSP00000122947	142 (aa)	-	D3Z7J9
ENSMUST00000127861	-	863	-	ENSMUSP00000119336	202 (aa)	-	D3Z2F2

Gene Model

Click here to download ENSMUSG00000025980's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03018	RNA degradation	KEGG
mmu04940	Type I diabetes mellitus	KEGG
mmu05134	Legionellosis	KEGG
mmu05152	Tuberculosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000025980's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000025980	Hspd1	100	98.592	ENSG00000144381	HSPD1	100	98.643	Homo_sapiens
ENSMUSG00000025980	Hspd1	96	58.993	YLR259C	HSP60	96	56.522	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0001530	lipopolysaccharide binding	17164250.	IDA	Function
GO:0001530	lipopolysaccharide binding	-	ISO	Function
GO:0002020	protease binding	-	ISO	Function
GO:0002039	p53 binding	-	ISO	Function
GO:0002368	B cell cytokine production	-	ISO	Process
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	-	ISO	Process
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	-	ISO	Process
GO:0003725	double-stranded RNA binding	21266579.	ISO	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005615	extracellular space	-	ISO	Component
GO:0005737	cytoplasm	21874024.	IDA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005739	mitochondrion	14651853.18614015.	HDA	Component
GO:0005739	mitochondrion	21873635.	IBA	Component
GO:0005739	mitochondrion	1516759.8824711.9867803.12931191.16959573.17923681.23976951.26767982.	IDA	Component
GO:0005739	mitochondrion	-	ISO	Component
GO:0005743	mitochondrial inner membrane	12865426.	HDA	Component
GO:0005743	mitochondrial inner membrane	-	ISO	Component
GO:0005759	mitochondrial matrix	-	ISO	Component
GO:0005769	early endosome	-	ISO	Component
GO:0005782	peroxisomal matrix	-	ISO	Component
GO:0005791	rough endoplasmic reticulum	-	ISO	Component
GO:0005794	Golgi apparatus	-	ISO	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005886	plasma membrane	15252132.	IDA	Component
GO:0005886	plasma membrane	-	ISO	Component
GO:0005905	clathrin-coated pit	-	ISO	Component
GO:0006457	protein folding	-	IEA	Process
GO:0006458	'de novo' protein folding	21873635.	IBA	Process
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	-	ISO	Process
GO:0006986	response to unfolded protein	-	ISO	Process
GO:0007005	mitochondrion organization	21873635.	IBA	Process
GO:0008035	high-density lipoprotein particle binding	-	ISO	Function
GO:0008637	apoptotic mitochondrial changes	21873635.	IBA	Process
GO:0008637	apoptotic mitochondrial changes	-	ISO	Process
GO:0009986	cell surface	-	ISO	Component
GO:0016020	membrane	20080761.	IMP	Component
GO:0016787	hydrolase activity	-	IEA	Function
GO:0019899	enzyme binding	-	ISO	Function
GO:0030061	mitochondrial crista	-	ISO	Component
GO:0030135	coated vesicle	-	ISO	Component
GO:0030141	secretory granule	1516759.8824711.	IDA	Component
GO:0030141	secretory granule	-	ISO	Component
GO:0030141	secretory granule	-	ISO	Component
GO:0031625	ubiquitin protein ligase binding	-	ISO	Function
GO:0032727	positive regulation of interferon-alpha production	17164250.	IDA	Process
GO:0032727	positive regulation of interferon-alpha production	-	ISO	Process
GO:0032729	positive regulation of interferon-gamma production	15371451.17164250.	IDA	Process
GO:0032729	positive regulation of interferon-gamma production	17164250.	IGI	Process
GO:0032729	positive regulation of interferon-gamma production	-	ISO	Process
GO:0032733	positive regulation of interleukin-10 production	-	ISO	Process
GO:0032735	positive regulation of interleukin-12 production	-	ISO	Process
GO:0032755	positive regulation of interleukin-6 production	-	ISO	Process
GO:0032991	protein-containing complex	-	ISO	Component
GO:0034185	apolipoprotein binding	-	ISO	Function
GO:0034186	apolipoprotein A-I binding	-	ISO	Function
GO:0042026	protein refolding	-	ISO	Process
GO:0042100	B cell proliferation	-	ISO	Process
GO:0042110	T cell activation	21873635.	IBA	Process
GO:0042110	T cell activation	15371451.17164250.18256040.	IDA	Process
GO:0042110	T cell activation	17164250.	IGI	Process
GO:0042110	T cell activation	-	ISO	Process
GO:0042113	B cell activation	-	ISO	Process
GO:0042588	zymogen granule	-	ISO	Component
GO:0043032	positive regulation of macrophage activation	-	ISO	Process
GO:0043065	positive regulation of apoptotic process	-	ISO	Process
GO:0043066	negative regulation of apoptotic process	-	ISO	Process
GO:0043209	myelin sheath	17634366.	HDA	Component
GO:0043231	intracellular membrane-bounded organelle	15136728.16708399.	IDA	Component
GO:0043524	negative regulation of neuron apoptotic process	-	ISO	Process
GO:0043559	insulin binding	-	ISO	Function
GO:0044406	adhesion of symbiont to host	20633027.	IDA	Process
GO:0044877	protein-containing complex binding	-	ISO	Function
GO:0045041	protein import into mitochondrial intermembrane space	21873635.	IBA	Process
GO:0045121	membrane raft	-	ISO	Component
GO:0046696	lipopolysaccharide receptor complex	-	ISO	Component
GO:0046982	protein heterodimerization activity	-	ISO	Function
GO:0048291	isotype switching to IgG isotypes	-	ISO	Process
GO:0050729	positive regulation of inflammatory response	-	ISO	Process
GO:0050821	protein stabilization	-	ISO	Process
GO:0050870	positive regulation of T cell activation	17164250.	IDA	Process
GO:0050870	positive regulation of T cell activation	-	ISO	Process
GO:0051082	unfolded protein binding	21873635.	IBA	Function
GO:0051087	chaperone binding	-	ISO	Function
GO:0051702	interaction with symbiont	-	ISO	Process
GO:0070062	extracellular exosome	-	ISO	Component
GO:0071866	negative regulation of apoptotic process in bone marrow	-	ISO	Process
GO:0098761	cellular response to interleukin-7	29581031.	IDA	Process
GO:0140030	modification-dependent protein binding	-	ISO	Function
GO:1903427	negative regulation of reactive oxygen species biosynthetic process	-	ISO	Process
GO:1904469	positive regulation of tumor necrosis factor secretion	-	ISO	Process
GO:2000778	positive regulation of interleukin-6 secretion	-	ISO	Process