EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000026288 (Gene tree)
Gene ID: 16331
Gene Symbol: Inpp5d
Alias: SHIP|SHIP-1|SHIP1|Src homology 2 domain-containing inositol-5-phosphatase|s-SHIP
Full Name: inositol polyphosphate-5-phosphatase D
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 100196 bases
Position: chr1:87620312-87720507
Accession: 107357
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000132384	Exo_endo_phos	PF03372.23	2.3e-09	1	1
ENSMUSP00000126569	Exo_endo_phos	PF03372.23	2.6e-09	1	1
ENSMUSP00000131244	Exo_endo_phos	PF03372.23	3.7e-09	1	1
ENSMUSP00000044647	Exo_endo_phos	PF03372.23	4e-09	1	1
ENSMUSP00000127941	Exo_endo_phos	PF03372.23	4e-09	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000167032	-	4125	-	ENSMUSP00000126569	928 (aa)	-	Q9ES52
ENSMUST00000169754	-	4937	XM_006529149	ENSMUSP00000127941	1191 (aa)	XP_006529212	Q9ES52
ENSMUST00000164592	-	2480	-	-	- (aa)	-	-
ENSMUST00000165554	-	370	-	ENSMUSP00000128700	124 (aa)	-	F7BZA7
ENSMUST00000170300	-	3942	-	ENSMUSP00000132384	867 (aa)	-	Q9ES52
ENSMUST00000168783	-	3854	XM_006529151	ENSMUSP00000131244	1130 (aa)	XP_006529214	Q9ES52
ENSMUST00000072999	-	4677	-	ENSMUSP00000072763	959 (aa)	-	Q9ES52
ENSMUST00000042275	-	4880	XM_006529150	ENSMUSP00000044647	1190 (aa)	XP_006529213	Q9ES52
ENSMUST00000163222	-	364	-	-	- (aa)	-	-
ENSMUST00000163548	-	577	-	-	- (aa)	-	-
ENSMUST00000163576	-	344	-	ENSMUSP00000130336	35 (aa)	-	E9Q752

Gene Model

Click here to download ENSMUSG00000026288's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu00562	Inositol phosphate metabolism	KEGG
mmu01100	Metabolic pathways	KEGG
mmu04070	Phosphatidylinositol signaling system	KEGG
mmu04662	B cell receptor signaling pathway	KEGG
mmu04664	Fc epsilon RI signaling pathway	KEGG
mmu04666	Fc gamma R-mediated phagocytosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000026288's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSMUSG00000026288	Inpp5d	91	47.841	ENSMUSG00000032737	Inppl1	99	61.871

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000026288	Inpp5d	100	92.998	ENSG00000168918	INPP5D	100	87.448	Homo_sapiens
ENSMUSG00000026288	Inpp5d	96	63.305	ENSAPOG00000017974	inpp5d	98	57.279	Acanthochromis_polyacanthus
ENSMUSG00000026288	Inpp5d	99	89.308	ENSAMEG00000016368	INPP5D	99	89.330	Ailuropoda_melanoleuca
ENSMUSG00000026288	Inpp5d	96	63.265	ENSAOCG00000003888	inpp5d	99	56.871	Amphiprion_ocellaris
ENSMUSG00000026288	Inpp5d	92	64.262	ENSAPEG00000020416	inpp5d	98	55.077	Amphiprion_percula
ENSMUSG00000026288	Inpp5d	99	61.634	ENSATEG00000011360	inpp5d	97	56.816	Anabas_testudineus
ENSMUSG00000026288	Inpp5d	97	81.633	ENSACAG00000006121	INPP5D	91	74.413	Anolis_carolinensis
ENSMUSG00000026288	Inpp5d	97	62.290	ENSACLG00000024736	inpp5d	99	55.955	Astatotilapia_calliptera
ENSMUSG00000026288	Inpp5d	98	58.728	ENSAMXG00000004736	inpp5d	97	57.270	Astyanax_mexicanus
ENSMUSG00000026288	Inpp5d	100	93.303	ENSBTAG00000020173	INPP5D	100	86.644	Bos_taurus
ENSMUSG00000026288	Inpp5d	100	93.151	ENSCJAG00000013979	INPP5D	100	87.772	Callithrix_jacchus
ENSMUSG00000026288	Inpp5d	100	93.455	ENSCAFG00000011650	INPP5D	88	87.256	Canis_familiaris
ENSMUSG00000026288	Inpp5d	100	93.455	ENSCAFG00020023772	INPP5D	99	87.535	Canis_lupus_dingo
ENSMUSG00000026288	Inpp5d	100	86.617	ENSCHIG00000018691	INPP5D	100	86.516	Capra_hircus
ENSMUSG00000026288	Inpp5d	100	93.912	ENSTSYG00000012323	INPP5D	100	88.413	Carlito_syrichta
ENSMUSG00000026288	Inpp5d	100	91.390	ENSCAPG00000013229	INPP5D	97	86.074	Cavia_aperea
ENSMUSG00000026288	Inpp5d	100	87.802	ENSCPOG00000011364	INPP5D	97	90.022	Cavia_porcellus
ENSMUSG00000026288	Inpp5d	100	87.823	ENSCCAG00000019399	INPP5D	99	85.272	Cebus_capucinus
ENSMUSG00000026288	Inpp5d	100	92.694	ENSCATG00000014660	INPP5D	100	84.171	Cercocebus_atys
ENSMUSG00000026288	Inpp5d	100	86.681	ENSCLAG00000015629	INPP5D	99	86.493	Chinchilla_lanigera
ENSMUSG00000026288	Inpp5d	100	92.694	ENSCSAG00000006368	INPP5D	100	87.353	Chlorocebus_sabaeus
ENSMUSG00000026288	Inpp5d	99	77.424	ENSCPBG00000024343	INPP5D	99	70.549	Chrysemys_picta_bellii
ENSMUSG00000026288	Inpp5d	100	89.498	ENSCANG00000040141	INPP5D	96	85.762	Colobus_angolensis_palliatus
ENSMUSG00000026288	Inpp5d	100	96.309	ENSCGRG00001023640	Inpp5d	99	97.174	Cricetulus_griseus_chok1gshd
ENSMUSG00000026288	Inpp5d	100	96.309	ENSCGRG00000003828	Inpp5d	100	96.121	Cricetulus_griseus_crigri
ENSMUSG00000026288	Inpp5d	98	58.053	ENSCSEG00000002919	inpp5d	97	55.277	Cynoglossus_semilaevis
ENSMUSG00000026288	Inpp5d	97	61.855	ENSCVAG00000015388	inpp5d	97	55.352	Cyprinodon_variegatus
ENSMUSG00000026288	Inpp5d	88	69.091	ENSDARG00000074283	inpp5d	98	66.385	Danio_rerio
ENSMUSG00000026288	Inpp5d	100	91.933	ENSDNOG00000006291	-	94	91.323	Dasypus_novemcinctus
ENSMUSG00000026288	Inpp5d	100	92.846	ENSDORG00000015370	Inpp5d	99	88.497	Dipodomys_ordii
ENSMUSG00000026288	Inpp5d	100	88.210	ENSEASG00005019862	INPP5D	99	88.003	Equus_asinus_asinus
ENSMUSG00000026288	Inpp5d	100	88.103	ENSECAG00000019497	INPP5D	100	88.003	Equus_caballus
ENSMUSG00000026288	Inpp5d	90	63.261	ENSELUG00000008208	inpp5d	97	53.718	Esox_lucius
ENSMUSG00000026288	Inpp5d	100	82.903	ENSFCAG00000011321	INPP5D	91	83.123	Felis_catus
ENSMUSG00000026288	Inpp5d	99	77.415	ENSFALG00000013517	INPP5D	95	73.542	Ficedula_albicollis
ENSMUSG00000026288	Inpp5d	99	87.789	ENSFDAG00000019347	INPP5D	97	90.759	Fukomys_damarensis
ENSMUSG00000026288	Inpp5d	99	61.029	ENSFHEG00000009590	inpp5d	98	55.802	Fundulus_heteroclitus
ENSMUSG00000026288	Inpp5d	80	64.972	ENSGMOG00000019190	inpp5d	93	66.667	Gadus_morhua
ENSMUSG00000026288	Inpp5d	88	85.000	ENSGALG00000035498	INPP5D	86	77.574	Gallus_gallus
ENSMUSG00000026288	Inpp5d	92	64.779	ENSGAFG00000017284	inpp5d	98	55.633	Gambusia_affinis
ENSMUSG00000026288	Inpp5d	92	66.254	ENSGACG00000003813	inpp5d	100	66.142	Gasterosteus_aculeatus
ENSMUSG00000026288	Inpp5d	99	77.285	ENSGAGG00000001443	INPP5D	99	70.793	Gopherus_agassizii
ENSMUSG00000026288	Inpp5d	91	93.368	ENSGGOG00000000530	INPP5D	94	93.368	Gorilla_gorilla
ENSMUSG00000026288	Inpp5d	97	62.290	ENSHBUG00000013397	inpp5d	99	55.955	Haplochromis_burtoni
ENSMUSG00000026288	Inpp5d	100	92.542	ENSHGLG00000003850	INPP5D	100	88.594	Heterocephalus_glaber_female
ENSMUSG00000026288	Inpp5d	100	92.542	ENSHGLG00100002826	INPP5D	99	87.143	Heterocephalus_glaber_male
ENSMUSG00000026288	Inpp5d	98	57.648	ENSHCOG00000014071	inpp5d	90	54.346	Hippocampus_comes
ENSMUSG00000026288	Inpp5d	91	65.262	ENSIPUG00000010594	inpp5d	97	55.990	Ictalurus_punctatus
ENSMUSG00000026288	Inpp5d	100	88.362	ENSSTOG00000011273	INPP5D	97	88.627	Ictidomys_tridecemlineatus
ENSMUSG00000026288	Inpp5d	100	91.828	ENSJJAG00000022473	Inpp5d	95	93.541	Jaculus_jaculus
ENSMUSG00000026288	Inpp5d	96	62.931	ENSKMAG00000014854	inpp5d	97	56.752	Kryptolebias_marmoratus
ENSMUSG00000026288	Inpp5d	96	63.118	ENSLBEG00000025835	inpp5d	99	55.128	Labrus_bergylta
ENSMUSG00000026288	Inpp5d	95	65.974	ENSLOCG00000005346	inpp5d	98	58.789	Lepisosteus_oculatus
ENSMUSG00000026288	Inpp5d	100	85.561	ENSLAFG00000016159	INPP5D	100	85.046	Loxodonta_africana
ENSMUSG00000026288	Inpp5d	100	92.846	ENSMFAG00000032897	INPP5D	99	87.347	Macaca_fascicularis
ENSMUSG00000026288	Inpp5d	100	89.498	ENSMMUG00000009772	INPP5D	99	85.595	Macaca_mulatta
ENSMUSG00000026288	Inpp5d	100	91.033	ENSMNEG00000028451	INPP5D	99	86.360	Macaca_nemestrina
ENSMUSG00000026288	Inpp5d	100	90.715	ENSMLEG00000037654	INPP5D	100	86.432	Mandrillus_leucophaeus
ENSMUSG00000026288	Inpp5d	99	62.423	ENSMAMG00000009985	inpp5d	98	56.846	Mastacembelus_armatus
ENSMUSG00000026288	Inpp5d	97	62.290	ENSMZEG00005008710	inpp5d	99	56.072	Maylandia_zebra
ENSMUSG00000026288	Inpp5d	95	84.814	ENSMGAG00000001607	INPP5D	91	78.750	Meleagris_gallopavo
ENSMUSG00000026288	Inpp5d	100	89.573	ENSMAUG00000007862	Inpp5d	95	89.573	Mesocricetus_auratus
ENSMUSG00000026288	Inpp5d	100	92.390	ENSMICG00000006753	INPP5D	100	87.248	Microcebus_murinus
ENSMUSG00000026288	Inpp5d	100	97.412	ENSMOCG00000020774	Inpp5d	100	95.617	Microtus_ochrogaster
ENSMUSG00000026288	Inpp5d	99	60.637	ENSMMOG00000005595	inpp5d	98	54.702	Mola_mola
ENSMUSG00000026288	Inpp5d	99	81.393	ENSMODG00000010448	INPP5D	100	82.751	Monodelphis_domestica
ENSMUSG00000026288	Inpp5d	92	65.502	ENSMALG00000016456	inpp5d	98	56.643	Monopterus_albus
ENSMUSG00000026288	Inpp5d	100	99.526	MGP_CAROLIEiJ_G0014384	Inpp5d	100	99.526	Mus_caroli
ENSMUSG00000026288	Inpp5d	100	98.935	MGP_PahariEiJ_G0027621	Inpp5d	100	98.761	Mus_pahari
ENSMUSG00000026288	Inpp5d	100	100.000	MGP_SPRETEiJ_G0015186	Inpp5d	100	100.000	Mus_spretus
ENSMUSG00000026288	Inpp5d	100	93.760	ENSMPUG00000005289	INPP5D	100	87.657	Mustela_putorius_furo
ENSMUSG00000026288	Inpp5d	100	87.045	ENSMLUG00000017391	INPP5D	99	86.561	Myotis_lucifugus
ENSMUSG00000026288	Inpp5d	100	93.985	ENSNGAG00000015967	Inpp5d	96	93.462	Nannospalax_galili
ENSMUSG00000026288	Inpp5d	99	60.963	ENSNBRG00000012987	inpp5d	99	55.882	Neolamprologus_brichardi
ENSMUSG00000026288	Inpp5d	98	85.381	ENSNLEG00000008201	INPP5D	92	79.313	Nomascus_leucogenys
ENSMUSG00000026288	Inpp5d	63	93.548	ENSMEUG00000002891	-	73	93.548	Notamacropus_eugenii
ENSMUSG00000026288	Inpp5d	87	89.963	ENSOPRG00000014301	INPP5D	92	85.452	Ochotona_princeps
ENSMUSG00000026288	Inpp5d	100	85.929	ENSODEG00000008216	INPP5D	97	85.294	Octodon_degus
ENSMUSG00000026288	Inpp5d	96	63.862	ENSONIG00000019319	inpp5d	96	66.615	Oreochromis_niloticus
ENSMUSG00000026288	Inpp5d	92	65.006	ENSORLG00000015584	inpp5d	98	56.080	Oryzias_latipes
ENSMUSG00000026288	Inpp5d	92	64.779	ENSORLG00020020270	inpp5d	98	55.906	Oryzias_latipes_hni
ENSMUSG00000026288	Inpp5d	92	65.006	ENSORLG00015000466	inpp5d	98	55.857	Oryzias_latipes_hsok
ENSMUSG00000026288	Inpp5d	92	64.480	ENSOMEG00000002876	inpp5d	98	55.791	Oryzias_melastigma
ENSMUSG00000026288	Inpp5d	100	84.459	ENSOGAG00000009128	INPP5D	100	84.506	Otolemur_garnettii
ENSMUSG00000026288	Inpp5d	100	86.724	ENSOARG00000019324	INPP5D	100	86.185	Ovis_aries
ENSMUSG00000026288	Inpp5d	100	93.151	ENSPPAG00000030895	INPP5D	100	87.280	Pan_paniscus
ENSMUSG00000026288	Inpp5d	100	88.614	ENSPPRG00000011130	INPP5D	100	87.594	Panthera_pardus
ENSMUSG00000026288	Inpp5d	99	86.979	ENSPTIG00000009805	INPP5D	98	84.254	Panthera_tigris_altaica
ENSMUSG00000026288	Inpp5d	100	93.151	ENSPTRG00000013050	INPP5D	100	87.197	Pan_troglodytes
ENSMUSG00000026288	Inpp5d	100	92.694	ENSPANG00000019973	INPP5D	100	87.605	Papio_anubis
ENSMUSG00000026288	Inpp5d	94	59.268	ENSPKIG00000025393	inpp5d	97	53.979	Paramormyrops_kingsleyae
ENSMUSG00000026288	Inpp5d	99	82.915	ENSPSIG00000002173	INPP5D	99	69.682	Pelodiscus_sinensis
ENSMUSG00000026288	Inpp5d	91	64.213	ENSPMGG00000018491	inpp5d	87	63.760	Periophthalmus_magnuspinnatus
ENSMUSG00000026288	Inpp5d	100	91.531	ENSPEMG00000007040	Inpp5d	99	90.863	Peromyscus_maniculatus_bairdii
ENSMUSG00000026288	Inpp5d	97	62.065	ENSPFOG00000021881	inpp5d	97	56.074	Poecilia_formosa
ENSMUSG00000026288	Inpp5d	98	57.931	ENSPLAG00000017156	inpp5d	97	54.818	Poecilia_latipinna
ENSMUSG00000026288	Inpp5d	97	61.749	ENSPMEG00000019565	inpp5d	97	55.898	Poecilia_mexicana
ENSMUSG00000026288	Inpp5d	97	61.595	ENSPREG00000016395	inpp5d	97	55.853	Poecilia_reticulata
ENSMUSG00000026288	Inpp5d	89	90.179	ENSPPYG00000013288	INPP5D	100	74.689	Pongo_abelii
ENSMUSG00000026288	Inpp5d	82	86.796	ENSPCAG00000007196	INPP5D	86	86.796	Procavia_capensis
ENSMUSG00000026288	Inpp5d	100	83.005	ENSPCOG00000018356	INPP5D	97	74.648	Propithecus_coquereli
ENSMUSG00000026288	Inpp5d	80	91.128	ENSPVAG00000007918	INPP5D	83	88.406	Pteropus_vampyrus
ENSMUSG00000026288	Inpp5d	98	58.409	ENSPNYG00000019357	inpp5d	98	56.272	Pundamilia_nyererei
ENSMUSG00000026288	Inpp5d	99	61.490	ENSPNAG00000027826	inpp5d	97	56.447	Pygocentrus_nattereri
ENSMUSG00000026288	Inpp5d	100	97.412	ENSRNOG00000017020	Inpp5d	100	96.807	Rattus_norvegicus
ENSMUSG00000026288	Inpp5d	100	89.650	ENSRBIG00000033999	INPP5D	99	86.025	Rhinopithecus_bieti
ENSMUSG00000026288	Inpp5d	100	92.998	ENSRROG00000030416	INPP5D	100	87.772	Rhinopithecus_roxellana
ENSMUSG00000026288	Inpp5d	100	92.998	ENSSBOG00000028279	INPP5D	100	87.866	Saimiri_boliviensis_boliviensis
ENSMUSG00000026288	Inpp5d	99	63.267	ENSSFOG00015006629	inpp5d	97	58.319	Scleropages_formosus
ENSMUSG00000026288	Inpp5d	99	61.880	ENSSMAG00000001138	inpp5d	97	57.105	Scophthalmus_maximus
ENSMUSG00000026288	Inpp5d	95	63.834	ENSSDUG00000021622	inpp5d	99	55.864	Seriola_dumerili
ENSMUSG00000026288	Inpp5d	95	62.177	ENSSLDG00000002786	inpp5d	98	55.236	Seriola_lalandi_dorsalis
ENSMUSG00000026288	Inpp5d	99	69.276	ENSSPUG00000014342	INPP5D	93	73.757	Sphenodon_punctatus
ENSMUSG00000026288	Inpp5d	96	62.047	ENSSPAG00000016922	inpp5d	99	56.716	Stegastes_partitus
ENSMUSG00000026288	Inpp5d	95	91.475	ENSSSCG00000016298	INPP5D	100	86.938	Sus_scrofa
ENSMUSG00000026288	Inpp5d	99	82.371	ENSTGUG00000007342	INPP5D	94	76.739	Taeniopygia_guttata
ENSMUSG00000026288	Inpp5d	92	64.036	ENSTRUG00000001313	inpp5d	97	55.702	Takifugu_rubripes
ENSMUSG00000026288	Inpp5d	84	80.206	ENSTTRG00000016300	INPP5D	83	90.517	Tursiops_truncatus
ENSMUSG00000026288	Inpp5d	100	87.633	ENSUAMG00000027664	INPP5D	95	87.412	Ursus_americanus
ENSMUSG00000026288	Inpp5d	99	88.248	ENSUMAG00000014489	INPP5D	93	90.081	Ursus_maritimus
ENSMUSG00000026288	Inpp5d	100	88.400	ENSVVUG00000025476	INPP5D	100	88.151	Vulpes_vulpes
ENSMUSG00000026288	Inpp5d	92	66.253	ENSXETG00000013875	inpp5d	99	60.172	Xenopus_tropicalis
ENSMUSG00000026288	Inpp5d	97	61.960	ENSXMAG00000016471	inpp5d	97	55.487	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002376	immune system process	-	IEA	Process
GO:0004445	inositol-polyphosphate 5-phosphatase activity	8643691.	IDA	Function
GO:0005515	protein binding	10068665.11031258.12874256.15102471.20526344.	IPI	Function
GO:0005737	cytoplasm	-	IEA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005856	cytoskeleton	-	IEA	Component
GO:0005884	actin filament	-	ISO	Component
GO:0005886	plasma membrane	-	ISO	Component
GO:0006915	apoptotic process	-	IEA	Process
GO:0008285	negative regulation of cell proliferation	8890215.	IDA	Process
GO:0008340	determination of adult lifespan	9620849.	IMP	Process
GO:0009968	negative regulation of signal transduction	9620849.10704460.12161749.	IMP	Process
GO:0016020	membrane	-	IEA	Component
GO:0016064	immunoglobulin mediated immune response	10704460.	IMP	Process
GO:0016787	hydrolase activity	-	IEA	Function
GO:0017124	SH3 domain binding	8643691.	IDA	Function
GO:0030487	inositol-4,5-bisphosphate 5-phosphatase activity	-	ISO	Function
GO:0030853	negative regulation of granulocyte differentiation	9620849.	IMP	Process
GO:0030863	cortical cytoskeleton	-	ISO	Component
GO:0030889	negative regulation of B cell proliferation	10704460.	IMP	Process
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	8890215.	IDA	Function
GO:0035556	intracellular signal transduction	10704460.	IMP	Process
GO:0043065	positive regulation of apoptotic process	12161749.	IMP	Process
GO:0045409	negative regulation of interleukin-6 biosynthetic process	12161749.	IMP	Process
GO:0045579	positive regulation of B cell differentiation	9620849.10704460.	IMP	Process
GO:0045621	positive regulation of lymphocyte differentiation	9620849.	IMP	Process
GO:0045648	positive regulation of erythrocyte differentiation	9620849.	IMP	Process
GO:0045656	negative regulation of monocyte differentiation	9620849.	IMP	Process
GO:0045659	negative regulation of neutrophil differentiation	9620849.	IMP	Process
GO:0045671	negative regulation of osteoclast differentiation	12161749.	IMP	Process
GO:0045779	negative regulation of bone resorption	12161749.	IMP	Process
GO:0046856	phosphatidylinositol dephosphorylation	-	IEA	Process
GO:0050777	negative regulation of immune response	10704460.	IMP	Process
GO:0050869	negative regulation of B cell activation	10704460.	IMP	Process
GO:0051425	PTB domain binding	8654924.	IDA	Function