EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000027433 (Gene tree)
Gene ID: 24128
Gene Symbol: Xrn2
Alias: -
Full Name: 5'-3' exoribonuclease 2
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Plus strand
Length: 65005 bases
Position: chr2:147012996-147078000
Accession: 894687
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000028921	XRN_N	PF03159.18	2e-102	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000147057	-	623	-	-	- (aa)	-	-
ENSMUST00000136136	-	575	-	-	- (aa)	-	-
ENSMUST00000137358	-	335	-	-	- (aa)	-	-
ENSMUST00000028921	-	3434	XM_006499450	ENSMUSP00000028921	951 (aa)	XP_006499514	Q9DBR1

Gene Model

Click here to download ENSMUSG00000027433's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03008	Ribosome biogenesis in eukaryotes	KEGG
mmu03018	RNA degradation	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000027433's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSMUSG00000027433	Xrn2	71	39.060	ENSMUSG00000032410	Xrn1	90	66.667

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000027433	Xrn2	100	96.004	ENSG00000088930	XRN2	100	96.004	Homo_sapiens
ENSMUSG00000027433	Xrn2	97	72.115	ENSAPOG00000009818	xrn2	100	70.846	Acanthochromis_polyacanthus
ENSMUSG00000027433	Xrn2	100	95.689	ENSAMEG00000012581	XRN2	100	95.689	Ailuropoda_melanoleuca
ENSMUSG00000027433	Xrn2	90	70.957	ENSACIG00000015047	xrn2	95	75.048	Amphilophus_citrinellus
ENSMUSG00000027433	Xrn2	97	72.650	ENSAOCG00000023632	xrn2	100	71.458	Amphiprion_ocellaris
ENSMUSG00000027433	Xrn2	97	72.572	ENSAPEG00000014871	xrn2	100	71.283	Amphiprion_percula
ENSMUSG00000027433	Xrn2	95	72.048	ENSATEG00000001273	xrn2	98	71.398	Anabas_testudineus
ENSMUSG00000027433	Xrn2	97	82.974	ENSAPLG00000013869	XRN2	99	83.405	Anas_platyrhynchos
ENSMUSG00000027433	Xrn2	100	80.042	ENSACAG00000005565	XRN2	100	80.042	Anolis_carolinensis
ENSMUSG00000027433	Xrn2	100	95.373	ENSANAG00000020126	XRN2	100	95.373	Aotus_nancymaae
ENSMUSG00000027433	Xrn2	90	74.018	ENSACLG00000010522	xrn2	96	76.667	Astatotilapia_calliptera
ENSMUSG00000027433	Xrn2	100	71.779	ENSAMXG00000018301	xrn2	100	71.779	Astyanax_mexicanus
ENSMUSG00000027433	Xrn2	100	93.487	ENSBTAG00000011304	XRN2	100	93.487	Bos_taurus
ENSMUSG00000027433	Xrn2	86	55.491	WBGene00006964	xrn-2	89	54.535	Caenorhabditis_elegans
ENSMUSG00000027433	Xrn2	100	95.478	ENSCJAG00000005611	XRN2	100	95.478	Callithrix_jacchus
ENSMUSG00000027433	Xrn2	100	95.689	ENSCAFG00000005185	XRN2	100	95.689	Canis_familiaris
ENSMUSG00000027433	Xrn2	100	95.689	ENSCAFG00020027479	XRN2	100	95.689	Canis_lupus_dingo
ENSMUSG00000027433	Xrn2	100	93.592	ENSCHIG00000006921	XRN2	100	93.592	Capra_hircus
ENSMUSG00000027433	Xrn2	100	94.953	ENSTSYG00000008315	XRN2	100	94.953	Carlito_syrichta
ENSMUSG00000027433	Xrn2	97	81.034	ENSCAPG00000010773	XRN2	99	80.927	Cavia_aperea
ENSMUSG00000027433	Xrn2	100	96.004	ENSCPOG00000009407	XRN2	100	96.004	Cavia_porcellus
ENSMUSG00000027433	Xrn2	100	96.109	ENSCATG00000040350	XRN2	100	96.109	Cercocebus_atys
ENSMUSG00000027433	Xrn2	100	96.109	ENSCLAG00000013419	XRN2	100	96.109	Chinchilla_lanigera
ENSMUSG00000027433	Xrn2	100	96.109	ENSCSAG00000011094	XRN2	100	96.109	Chlorocebus_sabaeus
ENSMUSG00000027433	Xrn2	68	99.462	ENSCHOG00000013404	XRN2	70	99.462	Choloepus_hoffmanni
ENSMUSG00000027433	Xrn2	100	84.062	ENSCPBG00000023533	XRN2	100	84.479	Chrysemys_picta_bellii
ENSMUSG00000027433	Xrn2	86	59.666	ENSCING00000022336	-	100	60.024	Ciona_intestinalis
ENSMUSG00000027433	Xrn2	98	53.943	ENSCSAVG00000011217	-	96	69.880	Ciona_savignyi
ENSMUSG00000027433	Xrn2	100	96.109	ENSCANG00000040240	XRN2	100	96.109	Colobus_angolensis_palliatus
ENSMUSG00000027433	Xrn2	98	97.097	ENSCGRG00001010676	Xrn2	99	97.097	Cricetulus_griseus_chok1gshd
ENSMUSG00000027433	Xrn2	97	96.336	ENSCGRG00000006378	Xrn2	99	96.336	Cricetulus_griseus_crigri
ENSMUSG00000027433	Xrn2	54	72.745	ENSCSEG00000005628	xrn2	100	72.745	Cynoglossus_semilaevis
ENSMUSG00000027433	Xrn2	89	71.379	ENSCVAG00000018999	xrn2	98	77.333	Cyprinodon_variegatus
ENSMUSG00000027433	Xrn2	100	70.359	ENSDARG00000101900	xrn2	96	78.394	Danio_rerio
ENSMUSG00000027433	Xrn2	100	95.058	ENSDNOG00000001895	XRN2	100	95.058	Dasypus_novemcinctus
ENSMUSG00000027433	Xrn2	100	93.481	ENSDORG00000005434	Xrn2	100	93.481	Dipodomys_ordii
ENSMUSG00000027433	Xrn2	86	56.364	FBgn0031868	Rat1	87	56.364	Drosophila_melanogaster
ENSMUSG00000027433	Xrn2	100	82.229	ENSETEG00000001740	XRN2	100	82.229	Echinops_telfairi
ENSMUSG00000027433	Xrn2	84	71.739	ENSEBUG00000016136	xrn2	100	71.739	Eptatretus_burgeri
ENSMUSG00000027433	Xrn2	100	95.268	ENSEASG00005002484	XRN2	100	95.268	Equus_asinus_asinus
ENSMUSG00000027433	Xrn2	99	95.359	ENSECAG00000018988	XRN2	96	100.000	Equus_caballus
ENSMUSG00000027433	Xrn2	80	100.000	ENSEEUG00000009265	XRN2	80	100.000	Erinaceus_europaeus
ENSMUSG00000027433	Xrn2	100	69.632	ENSELUG00000000552	xrn2	100	70.389	Esox_lucius
ENSMUSG00000027433	Xrn2	100	95.478	ENSFCAG00000007970	XRN2	100	95.478	Felis_catus
ENSMUSG00000027433	Xrn2	100	82.267	ENSFALG00000004508	XRN2	100	82.686	Ficedula_albicollis
ENSMUSG00000027433	Xrn2	100	95.689	ENSFDAG00000016311	XRN2	100	95.689	Fukomys_damarensis
ENSMUSG00000027433	Xrn2	54	69.962	ENSFHEG00000013039	xrn2	98	69.962	Fundulus_heteroclitus
ENSMUSG00000027433	Xrn2	86	73.390	ENSGMOG00000013436	xrn2	100	73.390	Gadus_morhua
ENSMUSG00000027433	Xrn2	100	82.704	ENSGALG00000008372	XRN2	100	82.704	Gallus_gallus
ENSMUSG00000027433	Xrn2	89	74.302	ENSGAFG00000014284	xrn2	98	74.302	Gambusia_affinis
ENSMUSG00000027433	Xrn2	87	75.301	ENSGACG00000011870	xrn2	96	78.571	Gasterosteus_aculeatus
ENSMUSG00000027433	Xrn2	100	83.854	ENSGAGG00000004884	XRN2	100	84.271	Gopherus_agassizii
ENSMUSG00000027433	Xrn2	100	96.215	ENSGGOG00000013738	XRN2	100	96.215	Gorilla_gorilla
ENSMUSG00000027433	Xrn2	54	74.664	ENSHBUG00000005077	xrn2	96	76.667	Haplochromis_burtoni
ENSMUSG00000027433	Xrn2	100	94.637	ENSHGLG00000014831	XRN2	100	94.427	Heterocephalus_glaber_female
ENSMUSG00000027433	Xrn2	100	94.637	ENSHGLG00100013130	XRN2	100	94.427	Heterocephalus_glaber_male
ENSMUSG00000027433	Xrn2	99	68.352	ENSHCOG00000011994	xrn2	99	69.270	Hippocampus_comes
ENSMUSG00000027433	Xrn2	100	69.929	ENSIPUG00000006639	xrn2	100	69.929	Ictalurus_punctatus
ENSMUSG00000027433	Xrn2	100	95.794	ENSSTOG00000000589	XRN2	100	95.794	Ictidomys_tridecemlineatus
ENSMUSG00000027433	Xrn2	100	95.794	ENSJJAG00000022128	Xrn2	100	95.794	Jaculus_jaculus
ENSMUSG00000027433	Xrn2	54	80.273	ENSLBEG00000010041	xrn2	100	80.273	Labrus_bergylta
ENSMUSG00000027433	Xrn2	93	76.633	ENSLACG00000008307	XRN2	99	79.141	Latimeria_chalumnae
ENSMUSG00000027433	Xrn2	99	72.490	ENSLOCG00000016874	xrn2	100	72.490	Lepisosteus_oculatus
ENSMUSG00000027433	Xrn2	100	94.427	ENSLAFG00000014624	XRN2	100	94.427	Loxodonta_africana
ENSMUSG00000027433	Xrn2	100	96.109	ENSMFAG00000038122	XRN2	100	96.109	Macaca_fascicularis
ENSMUSG00000027433	Xrn2	100	96.109	ENSMMUG00000011405	XRN2	100	96.109	Macaca_mulatta
ENSMUSG00000027433	Xrn2	100	96.004	ENSMNEG00000040626	XRN2	100	96.004	Macaca_nemestrina
ENSMUSG00000027433	Xrn2	100	96.004	ENSMLEG00000041897	XRN2	100	96.004	Mandrillus_leucophaeus
ENSMUSG00000027433	Xrn2	95	73.407	ENSMAMG00000008633	xrn2	97	72.825	Mastacembelus_armatus
ENSMUSG00000027433	Xrn2	90	75.982	ENSMZEG00005022362	xrn2	97	75.982	Maylandia_zebra
ENSMUSG00000027433	Xrn2	99	81.335	ENSMGAG00000003196	XRN2	99	81.335	Meleagris_gallopavo
ENSMUSG00000027433	Xrn2	100	96.951	ENSMAUG00000021842	Xrn2	100	96.951	Mesocricetus_auratus
ENSMUSG00000027433	Xrn2	100	95.058	ENSMICG00000008126	XRN2	100	95.058	Microcebus_murinus
ENSMUSG00000027433	Xrn2	100	96.740	ENSMOCG00000012588	Xrn2	100	96.740	Microtus_ochrogaster
ENSMUSG00000027433	Xrn2	89	73.998	ENSMMOG00000017576	xrn2	96	75.000	Mola_mola
ENSMUSG00000027433	Xrn2	100	89.695	ENSMODG00000006163	XRN2	100	89.695	Monodelphis_domestica
ENSMUSG00000027433	Xrn2	91	72.360	ENSMALG00000011355	xrn2	95	76.482	Monopterus_albus
ENSMUSG00000027433	Xrn2	100	99.685	MGP_CAROLIEiJ_G0024400	Xrn2	100	99.685	Mus_caroli
ENSMUSG00000027433	Xrn2	100	99.685	MGP_PahariEiJ_G0025843	Xrn2	100	99.685	Mus_pahari
ENSMUSG00000027433	Xrn2	100	100.000	MGP_SPRETEiJ_G0025318	Xrn2	100	100.000	Mus_spretus
ENSMUSG00000027433	Xrn2	100	93.905	ENSMPUG00000001198	XRN2	93	93.905	Mustela_putorius_furo
ENSMUSG00000027433	Xrn2	100	95.373	ENSMLUG00000001536	XRN2	100	95.373	Myotis_lucifugus
ENSMUSG00000027433	Xrn2	100	96.845	ENSNGAG00000018138	Xrn2	100	96.845	Nannospalax_galili
ENSMUSG00000027433	Xrn2	90	76.185	ENSNBRG00000008062	xrn2	97	76.185	Neolamprologus_brichardi
ENSMUSG00000027433	Xrn2	100	96.109	ENSNLEG00000009991	XRN2	100	96.109	Nomascus_leucogenys
ENSMUSG00000027433	Xrn2	66	97.778	ENSMEUG00000008622	-	67	97.778	Notamacropus_eugenii
ENSMUSG00000027433	Xrn2	75	79.058	ENSOPRG00000001397	-	77	79.058	Ochotona_princeps
ENSMUSG00000027433	Xrn2	98	86.530	ENSODEG00000000860	-	99	86.961	Octodon_degus
ENSMUSG00000027433	Xrn2	100	95.584	ENSODEG00000010745	-	100	95.584	Octodon_degus
ENSMUSG00000027433	Xrn2	100	71.649	ENSONIG00000018720	xrn2	100	71.930	Oreochromis_niloticus
ENSMUSG00000027433	Xrn2	100	89.927	ENSOANG00000015673	XRN2	100	89.927	Ornithorhynchus_anatinus
ENSMUSG00000027433	Xrn2	100	96.215	ENSOCUG00000013468	XRN2	100	96.215	Oryctolagus_cuniculus
ENSMUSG00000027433	Xrn2	98	70.747	ENSORLG00000017213	xrn2	97	75.289	Oryzias_latipes
ENSMUSG00000027433	Xrn2	98	70.968	ENSORLG00020001824	xrn2	100	70.612	Oryzias_latipes_hni
ENSMUSG00000027433	Xrn2	98	70.747	ENSORLG00015019747	xrn2	100	70.397	Oryzias_latipes_hsok
ENSMUSG00000027433	Xrn2	97	69.789	ENSOMEG00000019820	xrn2	100	69.402	Oryzias_melastigma
ENSMUSG00000027433	Xrn2	100	95.273	ENSOGAG00000001068	XRN2	100	95.273	Otolemur_garnettii
ENSMUSG00000027433	Xrn2	97	93.420	ENSOARG00000004443	XRN2	100	93.420	Ovis_aries
ENSMUSG00000027433	Xrn2	100	96.215	ENSPPAG00000033549	XRN2	100	96.215	Pan_paniscus
ENSMUSG00000027433	Xrn2	100	95.478	ENSPPRG00000008732	XRN2	100	95.478	Panthera_pardus
ENSMUSG00000027433	Xrn2	97	95.356	ENSPTIG00000015683	XRN2	97	95.356	Panthera_tigris_altaica
ENSMUSG00000027433	Xrn2	100	96.215	ENSPTRG00000013308	XRN2	100	96.215	Pan_troglodytes
ENSMUSG00000027433	Xrn2	100	96.109	ENSPANG00000018088	XRN2	100	96.109	Papio_anubis
ENSMUSG00000027433	Xrn2	100	71.136	ENSPKIG00000016889	xrn2	100	71.209	Paramormyrops_kingsleyae
ENSMUSG00000027433	Xrn2	80	87.109	ENSPSIG00000014666	XRN2	100	87.109	Pelodiscus_sinensis
ENSMUSG00000027433	Xrn2	100	96.635	ENSPEMG00000000111	Xrn2	100	96.635	Peromyscus_maniculatus_bairdii
ENSMUSG00000027433	Xrn2	100	69.990	ENSPFOG00000004182	xrn2	99	70.497	Poecilia_formosa
ENSMUSG00000027433	Xrn2	89	74.709	ENSPLAG00000007351	xrn2	96	74.709	Poecilia_latipinna
ENSMUSG00000027433	Xrn2	94	68.634	ENSPMEG00000011798	xrn2	99	69.097	Poecilia_mexicana
ENSMUSG00000027433	Xrn2	90	74.078	ENSPREG00000012452	xrn2	99	73.034	Poecilia_reticulata
ENSMUSG00000027433	Xrn2	100	95.689	ENSPPYG00000010755	XRN2	100	95.689	Pongo_abelii
ENSMUSG00000027433	Xrn2	100	89.087	ENSPCAG00000011191	XRN2	100	89.087	Procavia_capensis
ENSMUSG00000027433	Xrn2	100	88.223	ENSPCOG00000016468	XRN2	100	88.223	Propithecus_coquereli
ENSMUSG00000027433	Xrn2	93	90.909	ENSPVAG00000004596	XRN2	93	90.909	Pteropus_vampyrus
ENSMUSG00000027433	Xrn2	90	74.018	ENSPNYG00000001765	xrn2	97	74.018	Pundamilia_nyererei
ENSMUSG00000027433	Xrn2	100	71.792	ENSPNAG00000010956	xrn2	99	71.792	Pygocentrus_nattereri
ENSMUSG00000027433	Xrn2	100	97.687	ENSRNOG00000011785	Xrn2	100	97.687	Rattus_norvegicus
ENSMUSG00000027433	Xrn2	86	97.311	ENSRBIG00000036193	XRN2	100	97.311	Rhinopithecus_bieti
ENSMUSG00000027433	Xrn2	100	96.109	ENSRROG00000044400	XRN2	90	96.109	Rhinopithecus_roxellana
ENSMUSG00000027433	Xrn2	64	56.111	YOR048C	RAT1	63	53.846	Saccharomyces_cerevisiae
ENSMUSG00000027433	Xrn2	100	95.584	ENSSBOG00000021014	XRN2	100	95.584	Saimiri_boliviensis_boliviensis
ENSMUSG00000027433	Xrn2	100	72.033	ENSSFOG00015001091	xrn2	100	72.033	Scleropages_formosus
ENSMUSG00000027433	Xrn2	92	73.363	ENSSMAG00000007834	xrn2	100	68.927	Scophthalmus_maximus
ENSMUSG00000027433	Xrn2	91	72.624	ENSSDUG00000012802	xrn2	99	72.964	Seriola_dumerili
ENSMUSG00000027433	Xrn2	93	74.237	ENSSLDG00000021273	xrn2	100	74.237	Seriola_lalandi_dorsalis
ENSMUSG00000027433	Xrn2	76	100.000	ENSSARG00000005859	-	76	100.000	Sorex_araneus
ENSMUSG00000027433	Xrn2	98	78.953	ENSSPUG00000005485	XRN2	96	79.060	Sphenodon_punctatus
ENSMUSG00000027433	Xrn2	100	70.642	ENSSPAG00000016027	xrn2	99	70.727	Stegastes_partitus
ENSMUSG00000027433	Xrn2	100	93.796	ENSSSCG00000007109	XRN2	100	93.796	Sus_scrofa
ENSMUSG00000027433	Xrn2	100	80.982	ENSTGUG00000007535	XRN2	100	81.400	Taeniopygia_guttata
ENSMUSG00000027433	Xrn2	100	68.687	ENSTRUG00000015489	xrn2	100	69.130	Takifugu_rubripes
ENSMUSG00000027433	Xrn2	100	71.904	ENSTNIG00000010712	xrn2	100	71.904	Tetraodon_nigroviridis
ENSMUSG00000027433	Xrn2	100	94.953	ENSTBEG00000004119	XRN2	100	94.953	Tupaia_belangeri
ENSMUSG00000027433	Xrn2	93	96.937	ENSTTRG00000009087	XRN2	93	96.937	Tursiops_truncatus
ENSMUSG00000027433	Xrn2	100	95.794	ENSUAMG00000024634	XRN2	100	95.794	Ursus_americanus
ENSMUSG00000027433	Xrn2	97	95.464	ENSUMAG00000004012	XRN2	95	95.464	Ursus_maritimus
ENSMUSG00000027433	Xrn2	89	87.825	ENSVPAG00000010694	XRN2	91	87.825	Vicugna_pacos
ENSMUSG00000027433	Xrn2	100	95.584	ENSVVUG00000012178	XRN2	100	95.584	Vulpes_vulpes
ENSMUSG00000027433	Xrn2	100	73.597	ENSXETG00000023501	xrn2	100	74.220	Xenopus_tropicalis
ENSMUSG00000027433	Xrn2	100	68.583	ENSXMAG00000000242	xrn2	92	79.319	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000175	3'-5'-exoribonuclease activity	-	ISO	Function
GO:0000738	DNA catabolic process, exonucleolytic	-	ISO	Process
GO:0001147	transcription termination site sequence-specific DNA binding	-	ISO	Function
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0004518	nuclease activity	-	IEA	Function
GO:0004527	exonuclease activity	-	IEA	Function
GO:0004534	5'-3' exoribonuclease activity	7885830.	NAS	Function
GO:0005515	protein binding	22767893.	IPI	Function
GO:0005634	nucleus	-	ISO	Component
GO:0005730	nucleolus	-	ISO	Component
GO:0006139	nucleobase-containing compound metabolic process	-	IEA	Process
GO:0006281	DNA repair	7885830.	NAS	Process
GO:0006310	DNA recombination	7885830.	NAS	Process
GO:0006353	DNA-templated transcription, termination	-	IEA	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0007017	microtubule-based process	7885830.	TAS	Process
GO:0007283	spermatogenesis	7885830.	IEP	Process
GO:0008409	5'-3' exonuclease activity	-	ISO	Function
GO:0016070	RNA metabolic process	7885830.	IGI	Process
GO:0016235	aggresome	-	ISO	Component
GO:0016787	hydrolase activity	-	IEA	Function
GO:0046872	metal ion binding	-	IEA	Function