EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000027580 (Gene tree)
Gene ID: 229003
Gene Symbol: Helz2
Alias: BC006779
Full Name: helicase with zinc finger 2%2C transcriptional coactivator
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Minus strand
Length: 14413 bases
Position: chr2:181227615-181242027
Accession: 2385169
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000112917	RNB	PF00773.19	5.6e-51	1	1
ENSMUSP00000104459	RNB	PF00773.19	5.6e-51	1	1
ENSMUSP00000091756	RNB	PF00773.19	5.7e-51	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
25993413	Label-Free Protein RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression	IC & MEF	2015	Boucas J	DOI: 10.1371/journal.pone.0125745
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000108831	-	10109	XM_006500599	ENSMUSP00000104459	2947 (aa)	XP_006500662	E9QAM5
ENSMUST00000155049	-	2800	-	-	- (aa)	-	-
ENSMUST00000149417	-	7787	-	-	- (aa)	-	-
ENSMUST00000121484	-	10063	-	ENSMUSP00000112917	2903 (aa)	-	A2AS05
ENSMUST00000094203	-	9162	XM_006500601	ENSMUSP00000091756	2970 (aa)	XP_006500664	A2AS03

Gene Model

Click here to download ENSMUSG00000027580's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000027580's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000027580	Helz2	92	68.492	ENSG00000130589	HELZ2	100	68.666	Homo_sapiens
ENSMUSG00000027580	Helz2	99	68.354	ENSAMEG00000001622	HELZ2	99	68.160	Ailuropoda_melanoleuca
ENSMUSG00000027580	Helz2	89	58.266	ENSAPLG00000010386	HELZ2	99	58.266	Anas_platyrhynchos
ENSMUSG00000027580	Helz2	95	54.757	ENSACAG00000011519	HELZ2	99	55.357	Anolis_carolinensis
ENSMUSG00000027580	Helz2	92	66.815	ENSANAG00000019546	HELZ2	100	66.964	Aotus_nancymaae
ENSMUSG00000027580	Helz2	96	39.988	ENSAMXG00000017465	helz2	99	39.782	Astyanax_mexicanus
ENSMUSG00000027580	Helz2	99	67.343	ENSCAFG00000012968	HELZ2	100	66.970	Canis_familiaris
ENSMUSG00000027580	Helz2	90	70.640	ENSTSYG00000027453	HELZ2	100	70.522	Carlito_syrichta
ENSMUSG00000027580	Helz2	99	70.576	ENSCAPG00000010249	HELZ2	99	70.326	Cavia_aperea
ENSMUSG00000027580	Helz2	99	70.302	ENSCPOG00000006905	HELZ2	99	70.302	Cavia_porcellus
ENSMUSG00000027580	Helz2	92	67.624	ENSCCAG00000027744	HELZ2	100	67.747	Cebus_capucinus
ENSMUSG00000027580	Helz2	97	67.403	ENSCATG00000014259	HELZ2	100	66.617	Cercocebus_atys
ENSMUSG00000027580	Helz2	99	69.656	ENSCLAG00000006292	HELZ2	99	69.656	Chinchilla_lanigera
ENSMUSG00000027580	Helz2	97	67.706	ENSCSAG00000016417	HELZ2	99	67.740	Chlorocebus_sabaeus
ENSMUSG00000027580	Helz2	97	58.737	ENSCPBG00000014633	HELZ2	98	60.044	Chrysemys_picta_bellii
ENSMUSG00000027580	Helz2	92	68.217	ENSCANG00000033242	HELZ2	100	68.353	Colobus_angolensis_palliatus
ENSMUSG00000027580	Helz2	96	89.053	ENSCGRG00001016744	Helz2	100	84.753	Cricetulus_griseus_chok1gshd
ENSMUSG00000027580	Helz2	96	89.053	ENSCGRG00000012155	Helz2	100	84.753	Cricetulus_griseus_crigri
ENSMUSG00000027580	Helz2	62	48.837	ENSDARG00000012446	zgc:113057	97	48.491	Danio_rerio
ENSMUSG00000027580	Helz2	66	50.794	ENSDARG00000012600	si:dkey-97a13.6	98	50.902	Danio_rerio
ENSMUSG00000027580	Helz2	99	38.532	ENSDARG00000016527	helz2	99	38.946	Danio_rerio
ENSMUSG00000027580	Helz2	93	62.269	ENSDNOG00000017809	HELZ2	100	62.307	Dasypus_novemcinctus
ENSMUSG00000027580	Helz2	100	70.640	ENSDORG00000005596	Helz2	100	70.457	Dipodomys_ordii
ENSMUSG00000027580	Helz2	50	71.134	ENSETEG00000009947	-	62	71.134	Echinops_telfairi
ENSMUSG00000027580	Helz2	99	69.202	ENSEASG00005023168	HELZ2	99	69.202	Equus_asinus_asinus
ENSMUSG00000027580	Helz2	99	69.371	ENSECAG00000013636	HELZ2	99	70.867	Equus_caballus
ENSMUSG00000027580	Helz2	70	80.000	ENSEEUG00000004620	HELZ2	82	80.000	Erinaceus_europaeus
ENSMUSG00000027580	Helz2	93	52.929	ENSELUG00000013322	helz2	98	52.929	Esox_lucius
ENSMUSG00000027580	Helz2	95	56.455	ENSFALG00000005852	HELZ2	99	57.778	Ficedula_albicollis
ENSMUSG00000027580	Helz2	99	69.349	ENSFDAG00000013078	HELZ2	99	69.260	Fukomys_damarensis
ENSMUSG00000027580	Helz2	95	57.948	ENSGALG00000006138	HELZ2	99	57.948	Gallus_gallus
ENSMUSG00000027580	Helz2	94	59.432	ENSGAGG00000019429	HELZ2	99	59.432	Gopherus_agassizii
ENSMUSG00000027580	Helz2	92	68.068	ENSGGOG00000008640	HELZ2	100	68.007	Gorilla_gorilla
ENSMUSG00000027580	Helz2	98	74.473	ENSHGLG00000013895	HELZ2	99	74.784	Heterocephalus_glaber_female
ENSMUSG00000027580	Helz2	97	74.473	ENSHGLG00100002953	HELZ2	96	74.473	Heterocephalus_glaber_male
ENSMUSG00000027580	Helz2	61	45.328	ENSIPUG00000017627	zgc:113057	99	45.257	Ictalurus_punctatus
ENSMUSG00000027580	Helz2	100	69.743	ENSSTOG00000023572	HELZ2	100	69.946	Ictidomys_tridecemlineatus
ENSMUSG00000027580	Helz2	100	73.630	ENSJJAG00000021775	Helz2	100	73.767	Jaculus_jaculus
ENSMUSG00000027580	Helz2	99	42.962	ENSLACG00000008155	HELZ2	99	45.922	Latimeria_chalumnae
ENSMUSG00000027580	Helz2	97	45.904	ENSLOCG00000001839	si:dkey-97a13.6	99	45.911	Lepisosteus_oculatus
ENSMUSG00000027580	Helz2	99	41.442	ENSLOCG00000001770	helz2	99	41.442	Lepisosteus_oculatus
ENSMUSG00000027580	Helz2	92	67.997	ENSMFAG00000002329	HELZ2	100	68.307	Macaca_fascicularis
ENSMUSG00000027580	Helz2	97	67.648	ENSMMUG00000006070	HELZ2	100	68.282	Macaca_mulatta
ENSMUSG00000027580	Helz2	97	67.683	ENSMNEG00000044829	HELZ2	99	67.975	Macaca_nemestrina
ENSMUSG00000027580	Helz2	88	71.358	ENSMLEG00000034372	HELZ2	95	73.493	Mandrillus_leucophaeus
ENSMUSG00000027580	Helz2	99	47.910	ENSMGAG00000006941	HELZ2	99	49.518	Meleagris_gallopavo
ENSMUSG00000027580	Helz2	96	88.632	ENSMAUG00000000857	Helz2	100	83.655	Mesocricetus_auratus
ENSMUSG00000027580	Helz2	92	64.241	ENSMICG00000027046	HELZ2	100	64.291	Microcebus_murinus
ENSMUSG00000027580	Helz2	99	83.586	ENSMOCG00000016283	Helz2	100	83.049	Microtus_ochrogaster
ENSMUSG00000027580	Helz2	99	53.360	ENSMODG00000016966	-	99	53.327	Monodelphis_domestica
ENSMUSG00000027580	Helz2	100	97.524	MGP_CAROLIEiJ_G0024801	Helz2	100	97.524	Mus_caroli
ENSMUSG00000027580	Helz2	100	95.017	MGP_PahariEiJ_G0026249	Helz2	100	95.017	Mus_pahari
ENSMUSG00000027580	Helz2	100	99.084	MGP_SPRETEiJ_G0025727	Helz2	100	99.084	Mus_spretus
ENSMUSG00000027580	Helz2	99	65.899	ENSMPUG00000008361	HELZ2	99	65.797	Mustela_putorius_furo
ENSMUSG00000027580	Helz2	99	68.936	ENSMLUG00000014588	HELZ2	99	69.106	Myotis_lucifugus
ENSMUSG00000027580	Helz2	100	80.142	ENSNGAG00000013840	Helz2	100	80.142	Nannospalax_galili
ENSMUSG00000027580	Helz2	88	73.053	ENSNLEG00000010083	-	99	73.305	Nomascus_leucogenys
ENSMUSG00000027580	Helz2	88	66.667	ENSMEUG00000006147	HELZ2	96	68.371	Notamacropus_eugenii
ENSMUSG00000027580	Helz2	99	69.291	ENSODEG00000007200	HELZ2	99	71.882	Octodon_degus
ENSMUSG00000027580	Helz2	69	68.217	ENSOANG00000004941	-	99	51.909	Ornithorhynchus_anatinus
ENSMUSG00000027580	Helz2	99	67.037	ENSOGAG00000031068	HELZ2	99	67.332	Otolemur_garnettii
ENSMUSG00000027580	Helz2	92	68.231	ENSPPAG00000037593	HELZ2	100	68.245	Pan_paniscus
ENSMUSG00000027580	Helz2	91	67.826	ENSPPRG00000012585	HELZ2	99	67.639	Panthera_pardus
ENSMUSG00000027580	Helz2	91	67.992	ENSPTRG00000013743	HELZ2	98	68.006	Pan_troglodytes
ENSMUSG00000027580	Helz2	97	67.731	ENSPANG00000020634	HELZ2	100	66.927	Papio_anubis
ENSMUSG00000027580	Helz2	94	51.255	ENSPKIG00000005935	helz2	99	51.255	Paramormyrops_kingsleyae
ENSMUSG00000027580	Helz2	98	47.431	ENSPSIG00000012565	HELZ2	99	47.594	Pelodiscus_sinensis
ENSMUSG00000027580	Helz2	100	85.263	ENSPEMG00000016538	Helz2	99	88.842	Peromyscus_maniculatus_bairdii
ENSMUSG00000027580	Helz2	94	63.911	ENSPCIG00000017966	HELZ2	99	64.315	Phascolarctos_cinereus
ENSMUSG00000027580	Helz2	92	66.007	ENSPPYG00000011241	HELZ2	100	66.093	Pongo_abelii
ENSMUSG00000027580	Helz2	78	63.419	ENSPCAG00000001068	HELZ2	100	63.174	Procavia_capensis
ENSMUSG00000027580	Helz2	92	65.971	ENSPCOG00000017149	HELZ2	100	65.999	Propithecus_coquereli
ENSMUSG00000027580	Helz2	85	78.125	ENSPVAG00000007183	HELZ2	97	78.299	Pteropus_vampyrus
ENSMUSG00000027580	Helz2	88	50.515	ENSPNAG00000016859	helz2	99	50.515	Pygocentrus_nattereri
ENSMUSG00000027580	Helz2	99	88.957	ENSRNOG00000013267	Helz2	97	88.957	Rattus_norvegicus
ENSMUSG00000027580	Helz2	97	65.310	ENSRBIG00000044653	HELZ2	100	68.202	Rhinopithecus_bieti
ENSMUSG00000027580	Helz2	97	67.925	ENSRROG00000009088	HELZ2	100	67.033	Rhinopithecus_roxellana
ENSMUSG00000027580	Helz2	92	67.324	ENSSBOG00000033345	HELZ2	100	67.298	Saimiri_boliviensis_boliviensis
ENSMUSG00000027580	Helz2	97	59.582	ENSSHAG00000018163	HELZ2	99	59.582	Sarcophilus_harrisii
ENSMUSG00000027580	Helz2	93	49.004	ENSSFOG00015020580	helz2	98	49.296	Scleropages_formosus
ENSMUSG00000027580	Helz2	55	73.946	ENSSARG00000010235	-	68	73.946	Sorex_araneus
ENSMUSG00000027580	Helz2	99	61.070	ENSSSCG00000003306	HELZ2	99	61.070	Sus_scrofa
ENSMUSG00000027580	Helz2	85	47.218	ENSTGUG00000006981	HELZ2	99	52.645	Taeniopygia_guttata
ENSMUSG00000027580	Helz2	99	66.883	ENSUAMG00000025224	-	98	66.845	Ursus_americanus
ENSMUSG00000027580	Helz2	99	66.062	ENSVVUG00000015158	HELZ2	97	66.007	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21873635.	IBA	Process
GO:0003677	DNA binding	-	IEA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0004004	ATP-dependent RNA helicase activity	21873635.	IBA	Function
GO:0004386	helicase activity	-	IEA	Function
GO:0004540	ribonuclease activity	-	IEA	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0016787	hydrolase activity	-	IEA	Function
GO:0030374	nuclear receptor transcription coactivator activity	-	ISO	Function
GO:0045944	positive regulation of transcription by RNA polymerase II	-	ISO	Process
GO:0046872	metal ion binding	-	IEA	Function