EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000027810 (Gene tree)
Gene ID: 229317
Gene Symbol: Eif2a
Alias: D3Ertd194e
Full Name: eukaryotic translation initiation factor 2A
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Plus strand
Length: 31681 bases
Position: chr3:58525821-58557501
Accession: 1098684
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000029387	eIF2A	PF08662.11	5.1e-78	1	1
ENSMUSP00000120901	eIF2A	PF08662.11	1.6e-16	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000138848	-	913	-	ENSMUSP00000120901	251 (aa)	-	D3YZZ6
ENSMUST00000148251	-	3432	-	-	- (aa)	-	-
ENSMUST00000138827	-	2258	-	-	- (aa)	-	-
ENSMUST00000137469	-	1035	-	-	- (aa)	-	-
ENSMUST00000154219	-	1945	-	ENSMUSP00000121236	59 (aa)	-	D6RFN2
ENSMUST00000135876	-	1561	-	ENSMUSP00000122375	60 (aa)	-	D6RGA6
ENSMUST00000029387	-	2299	XM_006501321	ENSMUSP00000029387	581 (aa)	XP_006501384	Q8BJW6

Gene Model

Click here to download ENSMUSG00000027810's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000027810's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000027810	Eif2a	100	92.032	ENSG00000144895	EIF2A	100	92.821	Homo_sapiens
ENSMUSG00000027810	Eif2a	100	62.550	ENSAPOG00000008520	eif2a	98	63.066	Acanthochromis_polyacanthus
ENSMUSG00000027810	Eif2a	100	91.235	ENSAMEG00000010505	-	99	91.081	Ailuropoda_melanoleuca
ENSMUSG00000027810	Eif2a	100	63.492	ENSACIG00000024095	eif2a	92	65.961	Amphilophus_citrinellus
ENSMUSG00000027810	Eif2a	99	67.354	ENSAOCG00000006919	eif2a	98	67.838	Amphiprion_ocellaris
ENSMUSG00000027810	Eif2a	99	67.526	ENSAPEG00000019145	eif2a	98	68.014	Amphiprion_percula
ENSMUSG00000027810	Eif2a	99	67.010	ENSATEG00000019832	eif2a	98	67.368	Anabas_testudineus
ENSMUSG00000027810	Eif2a	100	87.251	ENSAPLG00000010076	EIF2A	98	84.965	Anas_platyrhynchos
ENSMUSG00000027810	Eif2a	100	80.478	ENSACAG00000007685	EIF2A	98	78.571	Anolis_carolinensis
ENSMUSG00000027810	Eif2a	100	92.829	ENSANAG00000038084	EIF2A	100	92.821	Aotus_nancymaae
ENSMUSG00000027810	Eif2a	99	66.265	ENSACLG00000009872	eif2a	98	66.725	Astatotilapia_calliptera
ENSMUSG00000027810	Eif2a	100	68.127	ENSAMXG00000013924	eif2a	98	70.087	Astyanax_mexicanus
ENSMUSG00000027810	Eif2a	100	90.085	ENSBTAG00000009106	EIF2A	100	90.085	Bos_taurus
ENSMUSG00000027810	Eif2a	99	34.558	WBGene00008480	eif-2A	97	35.324	Caenorhabditis_elegans
ENSMUSG00000027810	Eif2a	100	93.625	ENSCJAG00000001199	EIF2A	100	92.991	Callithrix_jacchus
ENSMUSG00000027810	Eif2a	100	91.966	ENSCAFG00000008407	EIF2A	100	91.966	Canis_familiaris
ENSMUSG00000027810	Eif2a	82	92.308	ENSCAFG00020004502	EIF2A	88	92.308	Canis_lupus_dingo
ENSMUSG00000027810	Eif2a	100	90.040	ENSCHIG00000023786	EIF2A	100	91.282	Capra_hircus
ENSMUSG00000027810	Eif2a	100	92.430	ENSTSYG00000014247	EIF2A	98	92.496	Carlito_syrichta
ENSMUSG00000027810	Eif2a	98	86.435	ENSCPOG00000006568	EIF2A	98	86.501	Cavia_porcellus
ENSMUSG00000027810	Eif2a	100	86.454	ENSCCAG00000026029	-	95	87.903	Cebus_capucinus
ENSMUSG00000027810	Eif2a	100	92.430	ENSCCAG00000032810	-	100	92.137	Cebus_capucinus
ENSMUSG00000027810	Eif2a	98	89.062	ENSCATG00000030017	EIF2A	97	89.062	Cercocebus_atys
ENSMUSG00000027810	Eif2a	100	91.966	ENSCLAG00000002863	EIF2A	100	91.966	Chinchilla_lanigera
ENSMUSG00000027810	Eif2a	100	92.430	ENSCSAG00000011568	EIF2A	100	92.308	Chlorocebus_sabaeus
ENSMUSG00000027810	Eif2a	100	76.027	ENSCHOG00000005256	EIF2A	94	76.491	Choloepus_hoffmanni
ENSMUSG00000027810	Eif2a	100	84.861	ENSCPBG00000014430	EIF2A	98	83.972	Chrysemys_picta_bellii
ENSMUSG00000027810	Eif2a	100	40.635	ENSCING00000002504	-	98	41.297	Ciona_intestinalis
ENSMUSG00000027810	Eif2a	99	43.836	ENSCSAVG00000003057	-	98	44.636	Ciona_savignyi
ENSMUSG00000027810	Eif2a	100	92.829	ENSCANG00000037097	EIF2A	100	92.321	Colobus_angolensis_palliatus
ENSMUSG00000027810	Eif2a	100	96.220	ENSCGRG00001016171	Eif2a	100	96.220	Cricetulus_griseus_chok1gshd
ENSMUSG00000027810	Eif2a	100	96.220	ENSCGRG00000009072	Eif2a	100	96.220	Cricetulus_griseus_crigri
ENSMUSG00000027810	Eif2a	97	65.785	ENSCSEG00000006247	eif2a	94	65.497	Cynoglossus_semilaevis
ENSMUSG00000027810	Eif2a	95	64.505	ENSCVAG00000001346	eif2a	99	66.739	Cyprinodon_variegatus
ENSMUSG00000027810	Eif2a	100	71.315	ENSDARG00000101061	eif2a	98	72.007	Danio_rerio
ENSMUSG00000027810	Eif2a	100	90.837	ENSDNOG00000014002	EIF2A	100	91.438	Dasypus_novemcinctus
ENSMUSG00000027810	Eif2a	100	89.641	ENSDORG00000012408	Eif2a	96	92.434	Dipodomys_ordii
ENSMUSG00000027810	Eif2a	97	39.764	FBgn0037135	CG7414	97	37.261	Drosophila_melanogaster
ENSMUSG00000027810	Eif2a	100	91.235	ENSETEG00000020032	EIF2A	98	84.615	Echinops_telfairi
ENSMUSG00000027810	Eif2a	100	58.167	ENSEBUG00000009787	eif2a	97	51.342	Eptatretus_burgeri
ENSMUSG00000027810	Eif2a	100	90.837	ENSEASG00005021392	EIF2A	100	91.282	Equus_asinus_asinus
ENSMUSG00000027810	Eif2a	100	90.438	ENSECAG00000024832	EIF2A	100	91.453	Equus_caballus
ENSMUSG00000027810	Eif2a	100	91.633	ENSEEUG00000011239	EIF2A	96	91.938	Erinaceus_europaeus
ENSMUSG00000027810	Eif2a	100	71.453	ENSELUG00000006270	eif2a	98	71.454	Esox_lucius
ENSMUSG00000027810	Eif2a	100	92.308	ENSFCAG00000011331	EIF2A	100	92.077	Felis_catus
ENSMUSG00000027810	Eif2a	100	82.869	ENSFALG00000005241	EIF2A	99	77.296	Ficedula_albicollis
ENSMUSG00000027810	Eif2a	100	91.235	ENSFDAG00000019484	EIF2A	95	92.147	Fukomys_damarensis
ENSMUSG00000027810	Eif2a	99	66.437	ENSFHEG00000008768	eif2a	99	64.860	Fundulus_heteroclitus
ENSMUSG00000027810	Eif2a	95	67.027	ENSGMOG00000001939	eif2a	100	67.027	Gadus_morhua
ENSMUSG00000027810	Eif2a	100	85.657	ENSGALG00000010401	EIF2A	98	84.495	Gallus_gallus
ENSMUSG00000027810	Eif2a	100	64.395	ENSGAFG00000016886	eif2a	98	65.969	Gambusia_affinis
ENSMUSG00000027810	Eif2a	99	61.986	ENSGACG00000004748	eif2a	98	62.238	Gasterosteus_aculeatus
ENSMUSG00000027810	Eif2a	100	84.462	ENSGAGG00000020541	EIF2A	98	83.798	Gopherus_agassizii
ENSMUSG00000027810	Eif2a	100	93.227	ENSGGOG00000015391	EIF2A	100	93.162	Gorilla_gorilla
ENSMUSG00000027810	Eif2a	99	66.265	ENSHBUG00000017252	eif2a	98	66.725	Haplochromis_burtoni
ENSMUSG00000027810	Eif2a	100	91.453	ENSHGLG00000019241	-	100	91.453	Heterocephalus_glaber_female
ENSMUSG00000027810	Eif2a	100	84.462	ENSHGLG00000002495	-	100	80.109	Heterocephalus_glaber_female
ENSMUSG00000027810	Eif2a	100	84.462	ENSHGLG00100005448	-	100	80.109	Heterocephalus_glaber_male
ENSMUSG00000027810	Eif2a	100	91.453	ENSHGLG00100008925	-	100	91.453	Heterocephalus_glaber_male
ENSMUSG00000027810	Eif2a	99	59.044	ENSHCOG00000006342	eif2a	98	59.582	Hippocampus_comes
ENSMUSG00000027810	Eif2a	100	70.120	ENSIPUG00000013822	eif2a	98	72.232	Ictalurus_punctatus
ENSMUSG00000027810	Eif2a	100	91.633	ENSSTOG00000003374	EIF2A	100	90.769	Ictidomys_tridecemlineatus
ENSMUSG00000027810	Eif2a	100	90.040	ENSJJAG00000011257	Eif2a	99	90.227	Jaculus_jaculus
ENSMUSG00000027810	Eif2a	99	66.323	ENSKMAG00000007156	eif2a	98	66.960	Kryptolebias_marmoratus
ENSMUSG00000027810	Eif2a	100	76.923	ENSLACG00000009147	EIF2A	100	76.923	Latimeria_chalumnae
ENSMUSG00000027810	Eif2a	100	72.908	ENSLOCG00000001831	eif2a	98	68.641	Lepisosteus_oculatus
ENSMUSG00000027810	Eif2a	100	90.438	ENSLAFG00000003767	EIF2A	98	91.623	Loxodonta_africana
ENSMUSG00000027810	Eif2a	100	92.829	ENSMFAG00000045972	EIF2A	100	92.650	Macaca_fascicularis
ENSMUSG00000027810	Eif2a	100	92.829	ENSMMUG00000017696	EIF2A	100	92.650	Macaca_mulatta
ENSMUSG00000027810	Eif2a	100	92.430	ENSMNEG00000034637	EIF2A	100	87.091	Macaca_nemestrina
ENSMUSG00000027810	Eif2a	100	92.829	ENSMLEG00000032824	EIF2A	100	92.479	Mandrillus_leucophaeus
ENSMUSG00000027810	Eif2a	97	66.667	ENSMAMG00000018484	eif2a	98	66.725	Mastacembelus_armatus
ENSMUSG00000027810	Eif2a	99	66.265	ENSMZEG00005001832	eif2a	98	66.725	Maylandia_zebra
ENSMUSG00000027810	Eif2a	94	84.322	ENSMGAG00000010935	EIF2A	97	84.133	Meleagris_gallopavo
ENSMUSG00000027810	Eif2a	100	95.618	ENSMAUG00000017191	Eif2a	100	95.181	Mesocricetus_auratus
ENSMUSG00000027810	Eif2a	100	93.227	ENSMICG00000049004	EIF2A	100	92.650	Microcebus_murinus
ENSMUSG00000027810	Eif2a	100	96.016	ENSMOCG00000017111	Eif2a	97	91.237	Microtus_ochrogaster
ENSMUSG00000027810	Eif2a	99	60.449	ENSMMOG00000009546	eif2a	97	60.847	Mola_mola
ENSMUSG00000027810	Eif2a	100	86.860	ENSMODG00000028858	EIF2A	100	86.860	Monodelphis_domestica
ENSMUSG00000027810	Eif2a	100	61.660	ENSMALG00000018747	eif2a	100	63.734	Monopterus_albus
ENSMUSG00000027810	Eif2a	100	99.484	MGP_CAROLIEiJ_G0025009	Eif2a	100	99.484	Mus_caroli
ENSMUSG00000027810	Eif2a	100	99.602	MGP_PahariEiJ_G0026453	Eif2a	100	99.602	Mus_pahari
ENSMUSG00000027810	Eif2a	100	100.000	MGP_SPRETEiJ_G0025949	Eif2a	100	100.000	Mus_spretus
ENSMUSG00000027810	Eif2a	100	92.137	ENSMPUG00000002592	EIF2A	100	92.137	Mustela_putorius_furo
ENSMUSG00000027810	Eif2a	100	91.633	ENSMLUG00000010497	EIF2A	99	90.799	Myotis_lucifugus
ENSMUSG00000027810	Eif2a	99	86.919	ENSNGAG00000007717	Eif2a	99	86.919	Nannospalax_galili
ENSMUSG00000027810	Eif2a	98	63.710	ENSNBRG00000007149	eif2a	95	66.058	Neolamprologus_brichardi
ENSMUSG00000027810	Eif2a	100	87.649	ENSNLEG00000003219	EIF2A	100	90.138	Nomascus_leucogenys
ENSMUSG00000027810	Eif2a	100	74.104	ENSMEUG00000000747	EIF2A	95	73.379	Notamacropus_eugenii
ENSMUSG00000027810	Eif2a	98	86.911	ENSOPRG00000014400	EIF2A	96	87.009	Ochotona_princeps
ENSMUSG00000027810	Eif2a	100	92.032	ENSODEG00000001987	-	94	90.698	Octodon_degus
ENSMUSG00000027810	Eif2a	85	92.982	ENSODEG00000000457	-	100	92.982	Octodon_degus
ENSMUSG00000027810	Eif2a	99	66.267	ENSONIG00000017284	eif2a	98	66.725	Oreochromis_niloticus
ENSMUSG00000027810	Eif2a	81	86.583	ENSOANG00000005785	EIF2A	96	86.583	Ornithorhynchus_anatinus
ENSMUSG00000027810	Eif2a	100	91.633	ENSOCUG00000016095	-	98	92.321	Oryctolagus_cuniculus
ENSMUSG00000027810	Eif2a	52	77.124	ENSOCUG00000007577	-	96	78.105	Oryctolagus_cuniculus
ENSMUSG00000027810	Eif2a	99	63.918	ENSORLG00015012728	eif2a	98	64.386	Oryzias_latipes_hsok
ENSMUSG00000027810	Eif2a	99	65.000	ENSOMEG00000016817	eif2a	98	65.493	Oryzias_melastigma
ENSMUSG00000027810	Eif2a	100	92.137	ENSOGAG00000010148	EIF2A	98	92.147	Otolemur_garnettii
ENSMUSG00000027810	Eif2a	100	90.438	ENSOARG00000004511	EIF2A	100	91.453	Ovis_aries
ENSMUSG00000027810	Eif2a	100	93.162	ENSPPAG00000043784	EIF2A	100	93.162	Pan_paniscus
ENSMUSG00000027810	Eif2a	100	91.633	ENSPPRG00000020244	EIF2A	100	92.137	Panthera_pardus
ENSMUSG00000027810	Eif2a	100	91.633	ENSPTIG00000017401	EIF2A	100	92.308	Panthera_tigris_altaica
ENSMUSG00000027810	Eif2a	100	93.162	ENSPTRG00000015528	EIF2A	100	93.162	Pan_troglodytes
ENSMUSG00000027810	Eif2a	100	92.829	ENSPANG00000017829	EIF2A	100	91.453	Papio_anubis
ENSMUSG00000027810	Eif2a	100	69.178	ENSPKIG00000014595	eif2a	95	69.298	Paramormyrops_kingsleyae
ENSMUSG00000027810	Eif2a	100	84.861	ENSPSIG00000005644	EIF2A	98	83.449	Pelodiscus_sinensis
ENSMUSG00000027810	Eif2a	93	63.919	ENSPMGG00000020947	eif2a	95	65.478	Periophthalmus_magnuspinnatus
ENSMUSG00000027810	Eif2a	100	97.074	ENSPEMG00000015613	Eif2a	100	97.074	Peromyscus_maniculatus_bairdii
ENSMUSG00000027810	Eif2a	100	87.372	ENSPCIG00000022274	EIF2A	100	87.372	Phascolarctos_cinereus
ENSMUSG00000027810	Eif2a	99	64.103	ENSPFOG00000008701	eif2a	98	65.445	Poecilia_formosa
ENSMUSG00000027810	Eif2a	99	64.274	ENSPLAG00000017279	eif2a	98	65.620	Poecilia_latipinna
ENSMUSG00000027810	Eif2a	99	64.103	ENSPMEG00000005215	eif2a	98	65.445	Poecilia_mexicana
ENSMUSG00000027810	Eif2a	98	59.109	ENSPREG00000021793	eif2a	85	59.524	Poecilia_reticulata
ENSMUSG00000027810	Eif2a	59	93.391	ENSPPYG00000029636	-	100	93.333	Pongo_abelii
ENSMUSG00000027810	Eif2a	100	85.259	ENSPCAG00000010767	EIF2A	94	83.072	Procavia_capensis
ENSMUSG00000027810	Eif2a	100	92.829	ENSPCOG00000024978	EIF2A	98	92.845	Propithecus_coquereli
ENSMUSG00000027810	Eif2a	100	90.438	ENSPVAG00000011535	EIF2A	95	90.093	Pteropus_vampyrus
ENSMUSG00000027810	Eif2a	99	66.265	ENSPNYG00000023276	eif2a	98	66.725	Pundamilia_nyererei
ENSMUSG00000027810	Eif2a	100	70.120	ENSPNAG00000022086	eif2a	98	72.007	Pygocentrus_nattereri
ENSMUSG00000027810	Eif2a	100	97.610	ENSRNOG00000013393	Eif2a	99	97.418	Rattus_norvegicus
ENSMUSG00000027810	Eif2a	100	91.966	ENSRBIG00000038363	EIF2A	100	91.966	Rhinopithecus_bieti
ENSMUSG00000027810	Eif2a	100	92.137	ENSRROG00000039293	EIF2A	100	92.137	Rhinopithecus_roxellana
ENSMUSG00000027810	Eif2a	95	92.887	ENSSBOG00000022479	EIF2A	100	92.266	Saimiri_boliviensis_boliviensis
ENSMUSG00000027810	Eif2a	77	82.533	ENSSHAG00000018554	EIF2A	100	82.533	Sarcophilus_harrisii
ENSMUSG00000027810	Eif2a	98	70.332	ENSSFOG00015017634	eif2a	98	70.332	Scleropages_formosus
ENSMUSG00000027810	Eif2a	99	67.642	ENSSMAG00000005233	eif2a	96	66.014	Scophthalmus_maximus
ENSMUSG00000027810	Eif2a	99	68.385	ENSSDUG00000005404	eif2a	98	68.717	Seriola_dumerili
ENSMUSG00000027810	Eif2a	99	68.213	ENSSLDG00000006171	eif2a	98	68.541	Seriola_lalandi_dorsalis
ENSMUSG00000027810	Eif2a	100	89.243	ENSSARG00000013191	EIF2A	95	91.323	Sorex_araneus
ENSMUSG00000027810	Eif2a	100	84.064	ENSSPUG00000010458	EIF2A	98	83.423	Sphenodon_punctatus
ENSMUSG00000027810	Eif2a	100	63.745	ENSSPAG00000005081	eif2a	99	67.974	Stegastes_partitus
ENSMUSG00000027810	Eif2a	100	90.040	ENSSSCG00000011710	EIF2A	100	90.940	Sus_scrofa
ENSMUSG00000027810	Eif2a	100	82.470	ENSTGUG00000011386	EIF2A	99	82.038	Taeniopygia_guttata
ENSMUSG00000027810	Eif2a	100	61.355	ENSTRUG00000002918	eif2a	93	63.333	Takifugu_rubripes
ENSMUSG00000027810	Eif2a	99	62.329	ENSTNIG00000011202	eif2a	94	62.435	Tetraodon_nigroviridis
ENSMUSG00000027810	Eif2a	100	90.438	ENSTBEG00000017179	EIF2A	96	87.692	Tupaia_belangeri
ENSMUSG00000027810	Eif2a	100	89.641	ENSTTRG00000007521	EIF2A	96	87.350	Tursiops_truncatus
ENSMUSG00000027810	Eif2a	100	90.837	ENSUAMG00000027103	EIF2A	99	91.424	Ursus_americanus
ENSMUSG00000027810	Eif2a	100	91.235	ENSUMAG00000012261	EIF2A	100	91.901	Ursus_maritimus
ENSMUSG00000027810	Eif2a	100	88.845	ENSVPAG00000006109	EIF2A	100	90.435	Vicugna_pacos
ENSMUSG00000027810	Eif2a	100	91.966	ENSVVUG00000011028	EIF2A	100	91.966	Vulpes_vulpes
ENSMUSG00000027810	Eif2a	100	79.283	ENSXETG00000020093	eif2a	100	76.764	Xenopus_tropicalis
ENSMUSG00000027810	Eif2a	98	61.538	ENSXCOG00000012657	eif2a	99	65.625	Xiphophorus_couchianus
ENSMUSG00000027810	Eif2a	99	65.582	ENSXMAG00000014008	eif2a	98	66.084	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000049	tRNA binding	21873635.	IBA	Function
GO:0000049	tRNA binding	-	ISO	Function
GO:0003743	translation initiation factor activity	21873635.	IBA	Function
GO:0003743	translation initiation factor activity	-	ISO	Function
GO:0005737	cytoplasm	-	ISO	Component
GO:0005850	eukaryotic translation initiation factor 2 complex	-	ISO	Component
GO:0006412	translation	7519779.	IDA	Process
GO:0006413	translational initiation	-	IEA	Process
GO:0006417	regulation of translation	-	ISO	Process
GO:0006468	protein phosphorylation	16705175.	IDA	Process
GO:0009967	positive regulation of signal transduction	18852460.	IDA	Process
GO:0022627	cytosolic small ribosomal subunit	21873635.	IBA	Component
GO:0032933	SREBP signaling pathway	18852460.	IDA	Process
GO:0042255	ribosome assembly	-	ISO	Process
GO:0043022	ribosome binding	21873635.	IBA	Function
GO:0043022	ribosome binding	-	ISO	Function
GO:1990928	response to amino acid starvation	-	ISO	Process