EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000028063 (Gene tree)
Gene ID: 16905
Gene Symbol: Lmna
Alias: Dhe|lamin A/C
Full Name: lamin A
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 29810
Position: chr3: 88480147-88509956
Accession: 96794
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000036252	-	1536	-	ENSMUSP00000040265	462 (aa)	-	P48678
ENSMUST00000029699	-	3156	XM_006501073	ENSMUSP00000029699	665 (aa)	XP_006501136	P48678
ENSMUST00000135494	-	901	-	-	- (aa)	-	-
ENSMUST00000147537	-	3948	-	-	- (aa)	-	-
ENSMUST00000150496	-	543	-	-	- (aa)	-	-
ENSMUST00000120377	-	2021	-	ENSMUSP00000113093	574 (aa)	-	P48678
ENSMUST00000149068	-	785	-	ENSMUSP00000120784	117 (aa)	-	D3YUF7

Gene Model

Click here to download ENSMUSG00000028063's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04210	Apoptosis	KEGG
mmu05410	Hypertrophic cardiomyopathy (HCM)	KEGG
mmu05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	KEGG
mmu05414	Dilated cardiomyopathy (DCM)	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000028063's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000028063	Lmna	100	100.000	ENSG00000160789	LMNA	100	99.087	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005198	structural molecule activity	-	IEA	Function
GO:0005515	protein binding	11739632.16380439.22349700.26436652.	IPI	Function
GO:0005634	nucleus	11739632.16731532.18664494.19915186.22886301.26436652.26657864.	IDA	Component
GO:0005634	nucleus	18809582.	ISO	Component
GO:0005635	nuclear envelope	18606848.20457914.23686339.	IDA	Component
GO:0005635	nuclear envelope	-	ISO	Component
GO:0005635	nuclear envelope	-	ISO	Component
GO:0005638	lamin filament	8032679.	IDA	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005882	intermediate filament	-	IEA	Component
GO:0006606	protein import into nucleus	14755333.	IMP	Process
GO:0006997	nucleus organization	16511604.	IGI	Process
GO:0006997	nucleus organization	14755333.	IMP	Process
GO:0006998	nuclear envelope organization	15608054.	IGI	Process
GO:0006998	nuclear envelope organization	-	ISO	Process
GO:0007517	muscle organ development	-	ISO	Process
GO:0008157	protein phosphatase 1 binding	-	ISO	Function
GO:0008285	negative regulation of cell proliferation	-	ISO	Process
GO:0010628	positive regulation of gene expression	22886301.	IMP	Process
GO:0016363	nuclear matrix	-	ISO	Component
GO:0030010	establishment of cell polarity	17631533.	NAS	Process
GO:0030334	regulation of cell migration	17631533.	IMP	Process
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	17631533.	IMP	Process
GO:0031647	regulation of protein stability	23695662.	IMP	Process
GO:0031965	nuclear membrane	11092755.17164264.	IDA	Component
GO:0032204	regulation of telomere maintenance	-	ISO	Process
GO:0034504	protein localization to nucleus	16339967.21498514.	IMP	Process
GO:0034613	cellular protein localization	-	ISO	Process
GO:0042802	identical protein binding	-	ISO	Function
GO:0045669	positive regulation of osteoblast differentiation	-	ISO	Process
GO:0048471	perinuclear region of cytoplasm	-	ISO	Component
GO:0055015	ventricular cardiac muscle cell development	14755333.	IMP	Process
GO:0072201	negative regulation of mesenchymal cell proliferation	22886301.	IMP	Process
GO:0090201	negative regulation of release of cytochrome c from mitochondria	21151901.	IMP	Process
GO:0090343	positive regulation of cell aging	-	ISO	Process
GO:1900114	positive regulation of histone H3-K9 trimethylation	23695662.	IMP	Process
GO:1900180	regulation of protein localization to nucleus	22349700.	IMP	Process
GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress	26436652.	IMP	Process
GO:1904178	negative regulation of adipose tissue development	-	ISO	Process
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	21151901.	IMP	Process