EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000028405 (Gene tree)
Gene ID: 11428
Gene Symbol: Aco1
Alias: Aco-1|Irebp|Irp1
Full Name: aconitase 1
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Plus strand
Length: 55258 bases
Position: chr4:40143081-40198338
Accession: 87879
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000100038	Aconitase	PF00330.20	4.8e-182	1	1
ENSMUSP00000100038	Aconitase_C	PF00694.19	2.7e-46	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000152911	-	714	-	-	- (aa)	-	-
ENSMUST00000142360	-	410	-	-	- (aa)	-	-
ENSMUST00000135787	-	638	-	-	- (aa)	-	-
ENSMUST00000102973	-	3832	-	ENSMUSP00000100038	889 (aa)	-	P28271

Gene Model

Click here to download ENSMUSG00000028405's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu00020	Citrate cycle (TCA cycle)	KEGG
mmu00630	Glyoxylate and dicarboxylate metabolism	KEGG
mmu01100	Metabolic pathways	KEGG
mmu01200	Carbon metabolism	KEGG
mmu01210	2-Oxocarboxylic acid metabolism	KEGG
mmu01230	Biosynthesis of amino acids	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000028405's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSMUSG00000028405	Aco1	99	62.450	ENSMUSG00000032293	Ireb2	98	57.919

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000028405	Aco1	100	93.363	ENSG00000122729	ACO1	100	93.363	Homo_sapiens
ENSMUSG00000028405	Aco1	100	83.015	ENSAPOG00000008670	aco1	99	83.015	Acanthochromis_polyacanthus
ENSMUSG00000028405	Aco1	100	92.472	ENSAMEG00000003746	ACO1	100	92.472	Ailuropoda_melanoleuca
ENSMUSG00000028405	Aco1	100	82.902	ENSACIG00000014377	aco1	99	82.902	Amphilophus_citrinellus
ENSMUSG00000028405	Aco1	100	83.352	ENSAOCG00000007699	aco1	99	83.352	Amphiprion_ocellaris
ENSMUSG00000028405	Aco1	100	83.240	ENSAPEG00000014370	aco1	99	83.240	Amphiprion_percula
ENSMUSG00000028405	Aco1	99	83.559	ENSATEG00000000560	aco1	99	83.559	Anabas_testudineus
ENSMUSG00000028405	Aco1	99	87.387	ENSAPLG00000015490	ACO1	99	87.387	Anas_platyrhynchos
ENSMUSG00000028405	Aco1	97	87.674	ENSACAG00000001541	ACO1	99	87.674	Anolis_carolinensis
ENSMUSG00000028405	Aco1	99	92.005	ENSANAG00000003359	ACO1	99	92.005	Aotus_nancymaae
ENSMUSG00000028405	Aco1	100	83.240	ENSACLG00000007755	aco1	99	83.240	Astatotilapia_calliptera
ENSMUSG00000028405	Aco1	99	83.221	ENSAMXG00000002499	aco1	99	83.315	Astyanax_mexicanus
ENSMUSG00000028405	Aco1	100	93.926	ENSBTAG00000000555	ACO1	100	93.926	Bos_taurus
ENSMUSG00000028405	Aco1	100	92.238	ENSCJAG00000007687	ACO1	100	92.238	Callithrix_jacchus
ENSMUSG00000028405	Aco1	100	92.584	ENSCAFG00000001786	ACO1	99	92.584	Canis_familiaris
ENSMUSG00000028405	Aco1	100	92.688	ENSCAFG00020014553	ACO1	100	92.688	Canis_lupus_dingo
ENSMUSG00000028405	Aco1	100	94.151	ENSCHIG00000007667	ACO1	100	94.151	Capra_hircus
ENSMUSG00000028405	Aco1	100	93.588	ENSTSYG00000004179	ACO1	99	93.588	Carlito_syrichta
ENSMUSG00000028405	Aco1	100	73.116	ENSCAPG00000007254	ACO1	100	73.003	Cavia_aperea
ENSMUSG00000028405	Aco1	100	91.564	ENSCPOG00000003768	ACO1	100	91.564	Cavia_porcellus
ENSMUSG00000028405	Aco1	100	91.901	ENSCCAG00000022465	ACO1	100	91.901	Cebus_capucinus
ENSMUSG00000028405	Aco1	100	93.026	ENSCATG00000045333	ACO1	100	93.026	Cercocebus_atys
ENSMUSG00000028405	Aco1	100	91.901	ENSCLAG00000002487	ACO1	100	91.901	Chinchilla_lanigera
ENSMUSG00000028405	Aco1	100	93.138	ENSCSAG00000009824	ACO1	99	93.138	Chlorocebus_sabaeus
ENSMUSG00000028405	Aco1	90	74.290	ENSCHOG00000008996	ACO1	90	74.174	Choloepus_hoffmanni
ENSMUSG00000028405	Aco1	99	89.077	ENSCPBG00000008077	ACO1	99	89.077	Chrysemys_picta_bellii
ENSMUSG00000028405	Aco1	100	92.913	ENSCANG00000014847	ACO1	100	92.913	Colobus_angolensis_palliatus
ENSMUSG00000028405	Aco1	100	97.638	ENSCGRG00001024337	Aco1	100	97.638	Cricetulus_griseus_chok1gshd
ENSMUSG00000028405	Aco1	100	96.513	ENSCGRG00000004877	-	100	96.513	Cricetulus_griseus_crigri
ENSMUSG00000028405	Aco1	99	78.805	ENSCSEG00000018262	aco1	99	78.805	Cynoglossus_semilaevis
ENSMUSG00000028405	Aco1	99	76.663	ENSCVAG00000020264	aco1	99	76.663	Cyprinodon_variegatus
ENSMUSG00000028405	Aco1	100	83.127	ENSDARG00000026376	aco1	99	83.127	Danio_rerio
ENSMUSG00000028405	Aco1	100	92.913	ENSDNOG00000003951	ACO1	100	92.913	Dasypus_novemcinctus
ENSMUSG00000028405	Aco1	100	93.251	ENSDORG00000014246	Aco1	100	93.251	Dipodomys_ordii
ENSMUSG00000028405	Aco1	86	70.899	ENSETEG00000012415	-	85	70.899	Echinops_telfairi
ENSMUSG00000028405	Aco1	99	58.712	ENSEBUG00000015441	aco1	97	58.712	Eptatretus_burgeri
ENSMUSG00000028405	Aco1	100	94.038	ENSEASG00005004602	ACO1	100	94.038	Equus_asinus_asinus
ENSMUSG00000028405	Aco1	100	93.926	ENSECAG00000014846	ACO1	100	93.926	Equus_caballus
ENSMUSG00000028405	Aco1	100	81.102	ENSEEUG00000015174	ACO1	100	81.102	Erinaceus_europaeus
ENSMUSG00000028405	Aco1	100	82.115	ENSELUG00000016812	aco1	97	82.115	Esox_lucius
ENSMUSG00000028405	Aco1	100	92.913	ENSFCAG00000001293	ACO1	100	92.913	Felis_catus
ENSMUSG00000028405	Aco1	99	87.387	ENSFALG00000001167	ACO1	99	87.387	Ficedula_albicollis
ENSMUSG00000028405	Aco1	100	92.238	ENSFDAG00000016058	ACO1	100	92.238	Fukomys_damarensis
ENSMUSG00000028405	Aco1	99	82.864	ENSFHEG00000005619	aco1	99	82.864	Fundulus_heteroclitus
ENSMUSG00000028405	Aco1	99	79.571	ENSGMOG00000005514	aco1	99	79.571	Gadus_morhua
ENSMUSG00000028405	Aco1	99	87.725	ENSGALG00000002162	ACO1	99	87.725	Gallus_gallus
ENSMUSG00000028405	Aco1	100	82.340	ENSGACG00000001637	aco1	99	82.340	Gasterosteus_aculeatus
ENSMUSG00000028405	Aco1	99	88.739	ENSGAGG00000023315	ACO1	99	88.739	Gopherus_agassizii
ENSMUSG00000028405	Aco1	100	93.138	ENSGGOG00000016306	ACO1	100	93.138	Gorilla_gorilla
ENSMUSG00000028405	Aco1	100	83.127	ENSHBUG00000008952	aco1	99	83.127	Haplochromis_burtoni
ENSMUSG00000028405	Aco1	100	93.026	ENSHGLG00000018922	Aco1	100	93.026	Heterocephalus_glaber_female
ENSMUSG00000028405	Aco1	100	93.026	ENSHGLG00100000149	Aco1	100	93.026	Heterocephalus_glaber_male
ENSMUSG00000028405	Aco1	99	79.707	ENSHCOG00000015881	aco1	99	79.707	Hippocampus_comes
ENSMUSG00000028405	Aco1	100	82.790	ENSIPUG00000020088	ACO1	99	82.790	Ictalurus_punctatus
ENSMUSG00000028405	Aco1	100	94.488	ENSSTOG00000006942	ACO1	99	94.488	Ictidomys_tridecemlineatus
ENSMUSG00000028405	Aco1	100	94.826	ENSJJAG00000013824	Aco1	100	94.826	Jaculus_jaculus
ENSMUSG00000028405	Aco1	99	82.545	ENSKMAG00000015759	aco1	99	82.545	Kryptolebias_marmoratus
ENSMUSG00000028405	Aco1	100	78.539	ENSLBEG00000013866	aco1	99	78.539	Labrus_bergylta
ENSMUSG00000028405	Aco1	75	73.739	ENSLACG00000000936	ACO1	99	73.582	Latimeria_chalumnae
ENSMUSG00000028405	Aco1	100	84.589	ENSLOCG00000011082	aco1	99	84.589	Lepisosteus_oculatus
ENSMUSG00000028405	Aco1	100	91.901	ENSLAFG00000013470	ACO1	100	91.901	Loxodonta_africana
ENSMUSG00000028405	Aco1	100	93.026	ENSMFAG00000001702	ACO1	100	93.026	Macaca_fascicularis
ENSMUSG00000028405	Aco1	100	93.138	ENSMMUG00000008196	ACO1	100	93.138	Macaca_mulatta
ENSMUSG00000028405	Aco1	100	92.913	ENSMNEG00000045040	ACO1	100	92.913	Macaca_nemestrina
ENSMUSG00000028405	Aco1	100	93.138	ENSMLEG00000005636	ACO1	100	93.138	Mandrillus_leucophaeus
ENSMUSG00000028405	Aco1	100	83.577	ENSMAMG00000002915	aco1	99	83.577	Mastacembelus_armatus
ENSMUSG00000028405	Aco1	99	79.731	ENSMZEG00005012733	aco1	99	79.395	Maylandia_zebra
ENSMUSG00000028405	Aco1	99	72.433	ENSMGAG00000008851	ACO1	99	72.433	Meleagris_gallopavo
ENSMUSG00000028405	Aco1	100	96.850	ENSMAUG00000021408	Aco1	100	96.850	Mesocricetus_auratus
ENSMUSG00000028405	Aco1	100	93.588	ENSMICG00000006540	ACO1	100	93.588	Microcebus_murinus
ENSMUSG00000028405	Aco1	100	96.738	ENSMOCG00000015393	Aco1	100	96.738	Microtus_ochrogaster
ENSMUSG00000028405	Aco1	100	81.552	ENSMMOG00000020282	aco1	99	81.552	Mola_mola
ENSMUSG00000028405	Aco1	100	89.876	ENSMODG00000004463	ACO1	100	89.876	Monodelphis_domestica
ENSMUSG00000028405	Aco1	100	82.902	ENSMALG00000019764	aco1	99	82.902	Monopterus_albus
ENSMUSG00000028405	Aco1	100	99.213	MGP_CAROLIEiJ_G0025892	Aco1	100	99.213	Mus_caroli
ENSMUSG00000028405	Aco1	100	98.875	MGP_PahariEiJ_G0024015	Aco1	100	98.875	Mus_pahari
ENSMUSG00000028405	Aco1	100	99.438	MGP_SPRETEiJ_G0026841	Aco1	100	99.438	Mus_spretus
ENSMUSG00000028405	Aco1	100	93.026	ENSMPUG00000004340	ACO1	100	93.026	Mustela_putorius_furo
ENSMUSG00000028405	Aco1	100	91.789	ENSMLUG00000003029	ACO1	100	91.789	Myotis_lucifugus
ENSMUSG00000028405	Aco1	100	95.838	ENSNGAG00000005703	Aco1	100	95.838	Nannospalax_galili
ENSMUSG00000028405	Aco1	100	65.213	ENSNBRG00000008973	aco1	99	64.989	Neolamprologus_brichardi
ENSMUSG00000028405	Aco1	100	93.476	ENSNLEG00000003409	ACO1	100	93.476	Nomascus_leucogenys
ENSMUSG00000028405	Aco1	90	82.916	ENSMEUG00000014756	ACO1	90	82.916	Notamacropus_eugenii
ENSMUSG00000028405	Aco1	100	89.539	ENSOPRG00000016791	ACO1	100	89.539	Ochotona_princeps
ENSMUSG00000028405	Aco1	100	90.664	ENSODEG00000001240	-	100	90.664	Octodon_degus
ENSMUSG00000028405	Aco1	100	88.189	ENSODEG00000015432	-	100	87.739	Octodon_degus
ENSMUSG00000028405	Aco1	100	83.015	ENSONIG00000019869	aco1	99	83.015	Oreochromis_niloticus
ENSMUSG00000028405	Aco1	81	91.010	ENSOANG00000012132	ACO1	100	91.010	Ornithorhynchus_anatinus
ENSMUSG00000028405	Aco1	100	91.657	ENSOCUG00000015960	ACO1	100	91.435	Oryctolagus_cuniculus
ENSMUSG00000028405	Aco1	99	83.446	ENSORLG00000020656	aco1	99	83.446	Oryzias_latipes
ENSMUSG00000028405	Aco1	99	82.995	ENSORLG00020010991	aco1	99	82.995	Oryzias_latipes_hni
ENSMUSG00000028405	Aco1	99	83.108	ENSORLG00015011785	aco1	99	83.108	Oryzias_latipes_hsok
ENSMUSG00000028405	Aco1	99	81.603	ENSOMEG00000000660	aco1	99	81.603	Oryzias_melastigma
ENSMUSG00000028405	Aco1	100	93.251	ENSOGAG00000010522	ACO1	100	93.251	Otolemur_garnettii
ENSMUSG00000028405	Aco1	100	94.151	ENSOARG00000014707	ACO1	98	94.151	Ovis_aries
ENSMUSG00000028405	Aco1	100	93.251	ENSPPAG00000033498	ACO1	100	93.251	Pan_paniscus
ENSMUSG00000028405	Aco1	100	92.913	ENSPPRG00000009875	ACO1	100	92.913	Panthera_pardus
ENSMUSG00000028405	Aco1	100	92.801	ENSPTIG00000016606	ACO1	98	92.801	Panthera_tigris_altaica
ENSMUSG00000028405	Aco1	100	93.251	ENSPTRG00000020843	ACO1	100	93.251	Pan_troglodytes
ENSMUSG00000028405	Aco1	100	93.138	ENSPANG00000025270	ACO1	100	93.138	Papio_anubis
ENSMUSG00000028405	Aco1	100	81.777	ENSPKIG00000023168	aco1	99	81.777	Paramormyrops_kingsleyae
ENSMUSG00000028405	Aco1	99	88.739	ENSPSIG00000008030	ACO1	99	88.739	Pelodiscus_sinensis
ENSMUSG00000028405	Aco1	99	83.653	ENSPMGG00000020708	aco1	99	83.653	Periophthalmus_magnuspinnatus
ENSMUSG00000028405	Aco1	100	96.738	ENSPEMG00000018464	Aco1	100	96.738	Peromyscus_maniculatus_bairdii
ENSMUSG00000028405	Aco1	100	89.651	ENSPCIG00000029321	ACO1	100	90.256	Phascolarctos_cinereus
ENSMUSG00000028405	Aco1	99	82.300	ENSPFOG00000013405	aco1	99	82.300	Poecilia_formosa
ENSMUSG00000028405	Aco1	90	83.625	ENSPLAG00000023422	aco1	98	83.625	Poecilia_latipinna
ENSMUSG00000028405	Aco1	90	83.541	ENSPMEG00000011800	aco1	98	83.541	Poecilia_mexicana
ENSMUSG00000028405	Aco1	99	82.300	ENSPREG00000021791	aco1	99	82.300	Poecilia_reticulata
ENSMUSG00000028405	Aco1	100	93.026	ENSPPYG00000019150	ACO1	95	93.026	Pongo_abelii
ENSMUSG00000028405	Aco1	78	94.340	ENSPCAG00000013222	ACO1	91	94.340	Procavia_capensis
ENSMUSG00000028405	Aco1	89	93.165	ENSPCOG00000021198	ACO1	100	93.165	Propithecus_coquereli
ENSMUSG00000028405	Aco1	96	87.617	ENSPVAG00000002372	ACO1	99	87.617	Pteropus_vampyrus
ENSMUSG00000028405	Aco1	100	83.127	ENSPNYG00000009425	aco1	99	83.127	Pundamilia_nyererei
ENSMUSG00000028405	Aco1	100	83.802	ENSPNAG00000017918	aco1	100	83.802	Pygocentrus_nattereri
ENSMUSG00000028405	Aco1	100	96.963	ENSRNOG00000005849	Aco1	100	96.963	Rattus_norvegicus
ENSMUSG00000028405	Aco1	100	92.913	ENSRBIG00000034592	ACO1	100	92.913	Rhinopithecus_bieti
ENSMUSG00000028405	Aco1	100	93.026	ENSRROG00000042672	ACO1	100	93.026	Rhinopithecus_roxellana
ENSMUSG00000028405	Aco1	100	92.463	ENSSBOG00000026008	ACO1	100	92.463	Saimiri_boliviensis_boliviensis
ENSMUSG00000028405	Aco1	100	89.775	ENSSHAG00000008924	ACO1	100	89.775	Sarcophilus_harrisii
ENSMUSG00000028405	Aco1	100	82.677	ENSSFOG00015018941	aco1	99	82.677	Scleropages_formosus
ENSMUSG00000028405	Aco1	75	83.731	ENSSMAG00000018908	aco1	80	83.634	Scophthalmus_maximus
ENSMUSG00000028405	Aco1	99	83.427	ENSSDUG00000002984	aco1	99	83.427	Seriola_dumerili
ENSMUSG00000028405	Aco1	99	83.653	ENSSLDG00000013952	aco1	99	83.653	Seriola_lalandi_dorsalis
ENSMUSG00000028405	Aco1	96	89.836	ENSSARG00000008437	ACO1	100	89.836	Sorex_araneus
ENSMUSG00000028405	Aco1	99	86.359	ENSSPUG00000002916	ACO1	99	86.359	Sphenodon_punctatus
ENSMUSG00000028405	Aco1	100	84.027	ENSSPAG00000019147	aco1	99	84.027	Stegastes_partitus
ENSMUSG00000028405	Aco1	100	94.038	ENSSSCG00000023807	ACO1	100	94.038	Sus_scrofa
ENSMUSG00000028405	Aco1	99	87.050	ENSTGUG00000001505	ACO1	99	87.050	Taeniopygia_guttata
ENSMUSG00000028405	Aco1	99	82.393	ENSTRUG00000006888	aco1	99	82.280	Takifugu_rubripes
ENSMUSG00000028405	Aco1	99	80.023	ENSTNIG00000005288	aco1	99	80.023	Tetraodon_nigroviridis
ENSMUSG00000028405	Aco1	100	89.651	ENSTBEG00000012369	ACO1	100	89.651	Tupaia_belangeri
ENSMUSG00000028405	Aco1	100	93.926	ENSTTRG00000016991	ACO1	99	93.926	Tursiops_truncatus
ENSMUSG00000028405	Aco1	100	92.688	ENSUAMG00000020699	ACO1	100	92.688	Ursus_americanus
ENSMUSG00000028405	Aco1	100	92.688	ENSUMAG00000005807	ACO1	100	92.688	Ursus_maritimus
ENSMUSG00000028405	Aco1	96	93.427	ENSVPAG00000009876	ACO1	100	93.427	Vicugna_pacos
ENSMUSG00000028405	Aco1	100	92.688	ENSVVUG00000021152	ACO1	91	92.688	Vulpes_vulpes
ENSMUSG00000028405	Aco1	99	85.169	ENSXETG00000009184	aco1	99	85.169	Xenopus_tropicalis
ENSMUSG00000028405	Aco1	50	81.406	ENSXCOG00000005638	aco1	96	81.406	Xiphophorus_couchianus
ENSMUSG00000028405	Aco1	99	82.525	ENSXMAG00000023603	aco1	99	82.525	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	-	ISO	Function
GO:0003994	aconitate hydratase activity	21873635.	IBA	Function
GO:0003994	aconitate hydratase activity	14726953.15604406.	IDA	Function
GO:0003994	aconitate hydratase activity	-	ISO	Function
GO:0005737	cytoplasm	8262972.	IDA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005739	mitochondrion	18614015.	HDA	Component
GO:0005739	mitochondrion	21873635.	IBA	Component
GO:0005739	mitochondrion	-	ISO	Component
GO:0005783	endoplasmic reticulum	-	ISO	Component
GO:0005794	Golgi apparatus	-	ISO	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	14726953.16144863.	IDA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0006099	tricarboxylic acid cycle	21873635.	IBA	Process
GO:0006101	citrate metabolic process	21873635.	IBA	Process
GO:0006101	citrate metabolic process	-	ISO	Process
GO:0006417	regulation of translation	14726953.	IMP	Process
GO:0006879	cellular iron ion homeostasis	14726953.	IGI	Process
GO:0006879	cellular iron ion homeostasis	14726953.	IMP	Process
GO:0006879	cellular iron ion homeostasis	-	ISO	Process
GO:0009791	post-embryonic development	18177727.	IGI	Process
GO:0010040	response to iron(II) ion	-	ISO	Process
GO:0010468	regulation of gene expression	18177727.	IGI	Process
GO:0016829	lyase activity	-	IEA	Function
GO:0030350	iron-responsive element binding	8262972.14726953.15604406.15629469.	IDA	Function
GO:0030350	iron-responsive element binding	-	ISO	Function
GO:0043231	intracellular membrane-bounded organelle	-	ISO	Component
GO:0046872	metal ion binding	-	IEA	Function
GO:0048027	mRNA 5'-UTR binding	-	ISO	Function
GO:0050892	intestinal absorption	18177727.	IGI	Process
GO:0051536	iron-sulfur cluster binding	-	ISO	Function
GO:0051538	3 iron, 4 sulfur cluster binding	21873635.	IBA	Function
GO:0051538	3 iron, 4 sulfur cluster binding	-	ISO	Function
GO:0051539	4 iron, 4 sulfur cluster binding	21873635.	IBA	Function
GO:0051539	4 iron, 4 sulfur cluster binding	-	ISO	Function