EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000028452 (Gene tree)
Gene ID: 269523
Gene Symbol: Vcp
Alias: AAA ATPase p97|CDC48|p97|p97/VCP
Full Name: valosin containing protein
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 20545
Position: chr4: 42979963-43000507
Accession: 99919
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000154423	-	707	-	-	- (aa)	-	-
ENSMUST00000148182	-	539	-	-	- (aa)	-	-
ENSMUST00000030164	-	3316	-	ENSMUSP00000030164	806 (aa)	-	Q01853
ENSMUST00000154541	-	894	-	-	- (aa)	-	-
ENSMUST00000139843	-	618	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000028452's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04141	Protein processing in endoplasmic reticulum	KEGG
mmu05134	Legionellosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000028452's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000028452	Vcp	99	83.188	FBgn0261014	TER94	97	85.190	Drosophila_melanogaster
ENSMUSG00000028452	Vcp	100	100.000	ENSG00000165280	VCP	100	100.000	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0000502	proteasome complex	-	ISO	Component
GO:0005102	signaling receptor binding	-	ISO	Function
GO:0005515	protein binding	10811609.11689694.12504083.12847084.14561754.14988733.15215856.15723043.16525503.16709668.17202270.17496150.18178578.19805280.20691684.21070972.21600962.22232657.22773186.23055941.24160817.24424410.	IPI	Function
GO:0005524	ATP binding	12847084.	IDA	Function
GO:0005524	ATP binding	15740751.	IMP	Function
GO:0005524	ATP binding	-	ISO	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005783	endoplasmic reticulum	-	ISO	Component
GO:0005789	endoplasmic reticulum membrane	12847084.	IDA	Component
GO:0005789	endoplasmic reticulum membrane	-	ISO	Component
GO:0005811	lipid droplet	-	ISO	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	23444373.	ISO	Component
GO:0006281	DNA repair	-	IEA	Process
GO:0006302	double-strand break repair	-	ISO	Process
GO:0006511	ubiquitin-dependent protein catabolic process	16810319.	IGI	Process
GO:0006734	NADH metabolic process	-	ISO	Process
GO:0006888	ER to Golgi vesicle-mediated transport	-	ISO	Process
GO:0006914	autophagy	-	ISO	Process
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	14561754.	IDA	Process
GO:0006974	cellular response to DNA damage stimulus	-	ISO	Process
GO:0008289	lipid binding	-	IEA	Function
GO:0010494	cytoplasmic stress granule	-	ISO	Component
GO:0010498	proteasomal protein catabolic process	-	ISO	Process
GO:0010918	positive regulation of mitochondrial membrane potential	23498975.	IMP	Process
GO:0010918	positive regulation of mitochondrial membrane potential	-	ISO	Process
GO:0016236	macroautophagy	21873635.	IBA	Process
GO:0016236	macroautophagy	-	ISO	Process
GO:0016567	protein ubiquitination	-	ISO	Process
GO:0016787	hydrolase activity	-	IEA	Function
GO:0016887	ATPase activity	21873635.	IBA	Function
GO:0016887	ATPase activity	12847084.	IDA	Function
GO:0016887	ATPase activity	-	ISO	Function
GO:0018279	protein N-linked glycosylation via asparagine	-	ISO	Process
GO:0019079	viral genome replication	-	ISO	Process
GO:0019903	protein phosphatase binding	-	ISO	Function
GO:0019904	protein domain specific binding	-	ISO	Function
GO:0019985	translesion synthesis	-	ISO	Process
GO:0030433	ubiquitin-dependent ERAD pathway	21873635.	IBA	Process
GO:0030433	ubiquitin-dependent ERAD pathway	-	ISO	Process
GO:0030970	retrograde protein transport, ER to cytosol	21873635.	IBA	Process
GO:0030970	retrograde protein transport, ER to cytosol	12847084.	IMP	Process
GO:0030970	retrograde protein transport, ER to cytosol	-	ISO	Process
GO:0031334	positive regulation of protein complex assembly	-	ISO	Process
GO:0031593	polyubiquitin modification-dependent protein binding	21873635.	IBA	Function
GO:0031593	polyubiquitin modification-dependent protein binding	11483959.	IDA	Function
GO:0031593	polyubiquitin modification-dependent protein binding	-	ISO	Function
GO:0031625	ubiquitin protein ligase binding	-	ISO	Function
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	-	ISO	Process
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	-	ISO	Process
GO:0032991	protein-containing complex	17785525.	IPI	Component
GO:0032991	protein-containing complex	-	ISO	Component
GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	21873635.	IBA	Component
GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	10811609.17000876.	IDA	Component
GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	12847084.	IPI	Component
GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	-	ISO	Component
GO:0034214	protein hexamerization	10811609.12847084.	IDA	Process
GO:0034214	protein hexamerization	15740751.	IMP	Process
GO:0034214	protein hexamerization	-	ISO	Process
GO:0034605	cellular response to heat	-	ISO	Process
GO:0035617	stress granule disassembly	-	ISO	Process
GO:0035800	deubiquitinase activator activity	-	ISO	Function
GO:0035861	site of double-strand break	-	ISO	Component
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	12847084.	IDA	Function
GO:0036503	ERAD pathway	-	ISO	Process
GO:0036513	Derlin-1 retrotranslocation complex	15215856.	IDA	Component
GO:0036513	Derlin-1 retrotranslocation complex	-	ISO	Component
GO:0042288	MHC class I protein binding	12847084.	IDA	Function
GO:0042802	identical protein binding	15740751.	IMP	Function
GO:0042802	identical protein binding	18462676.22232657.	IPI	Function
GO:0042802	identical protein binding	-	ISO	Function
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	26692333.	IMP	Process
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	-	ISO	Process
GO:0043209	myelin sheath	17634366.	HDA	Component
GO:0043231	intracellular membrane-bounded organelle	-	ISO	Component
GO:0043531	ADP binding	15740751.	IMP	Function
GO:0043531	ADP binding	-	ISO	Function
GO:0044389	ubiquitin-like protein ligase binding	-	ISO	Function
GO:0044877	protein-containing complex binding	-	ISO	Function
GO:0045202	synapse	16635246.24534009.	EXP	Component
GO:0045202	synapse	16635246.24534009.	IDA	Component
GO:0045732	positive regulation of protein catabolic process	-	ISO	Process
GO:0046034	ATP metabolic process	12847084.	IDA	Process
GO:0048471	perinuclear region of cytoplasm	-	ISO	Component
GO:0050807	regulation of synapse organization	-	ISO	Process
GO:0051228	mitotic spindle disassembly	21873635.	IBA	Process
GO:0051260	protein homooligomerization	-	ISO	Process
GO:0061857	endoplasmic reticulum stress-induced pre-emptive quality control	-	ISO	Process
GO:0070842	aggresome assembly	16810319.	IGI	Process
GO:0071712	ER-associated misfolded protein catabolic process	21873635.	IBA	Process
GO:0071712	ER-associated misfolded protein catabolic process	-	ISO	Process
GO:0072389	flavin adenine dinucleotide catabolic process	-	ISO	Process
GO:0090263	positive regulation of canonical Wnt signaling pathway	-	ISO	Process
GO:0097352	autophagosome maturation	21873635.	IBA	Process
GO:0097352	autophagosome maturation	-	ISO	Process
GO:0098978	glutamatergic synapse	-	ISO	Component
GO:1903006	positive regulation of protein K63-linked deubiquitination	-	ISO	Process
GO:1903007	positive regulation of Lys63-specific deubiquitinase activity	-	ISO	Process
GO:1903715	regulation of aerobic respiration	-	ISO	Process
GO:1903843	cellular response to arsenite ion	-	ISO	Process
GO:1903862	positive regulation of oxidative phosphorylation	-	ISO	Process
GO:1904288	BAT3 complex binding	-	ISO	Function
GO:1904949	ATPase complex	15740751.	IMP	Component
GO:1990381	ubiquitin-specific protease binding	17000876.	IPI	Function
GO:1990381	ubiquitin-specific protease binding	-	ISO	Function
GO:1990730	VCP-NSFL1C complex	10811609.12847084.	IPI	Component
GO:1990730	VCP-NSFL1C complex	-	ISO	Component
GO:2001171	positive regulation of ATP biosynthetic process	-	ISO	Process