EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000028911 (Gene tree)
Gene ID: 57317
Gene Symbol: Srsf4
Alias: 5730499P16Rik|MNCb-2616|SRp75|Sfrs4
Full Name: serine/arginine-rich splicing factor 4
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Plus strand
Length: 28090 bases
Position: chr4:131873617-131901706
Accession: 1890577
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000061474	RRM_1	PF00076.22	5.3e-31	1	2
ENSMUSP00000061474	RRM_1	PF00076.22	5.3e-31	2	2

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000129966	-	851	-	ENSMUSP00000141468	56 (aa)	-	A0A0A6YWA5
ENSMUST00000053819	-	2257	XM_017320333	ENSMUSP00000061474	491 (aa)	XP_017175822	Q542V3
ENSMUST00000030743	-	3100	-	-	- (aa)	-	-
ENSMUST00000134943	-	980	-	ENSMUSP00000142148	31 (aa)	-	A0A0A6YXU8

Gene Model

Click here to download ENSMUSG00000028911's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03040	Spliceosome	KEGG
mmu05168	Herpes simplex virus 1 infection	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000028911's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000028911	Srsf4	92	83.991	ENSG00000116350	SRSF4	93	83.766	Homo_sapiens
ENSMUSG00000028911	Srsf4	92	84.233	ENSAMEG00000000594	SRSF4	93	80.388	Ailuropoda_melanoleuca
ENSMUSG00000028911	Srsf4	85	71.084	ENSAPLG00000006595	-	92	71.053	Anas_platyrhynchos
ENSMUSG00000028911	Srsf4	87	83.102	ENSANAG00000037134	SRSF4	100	84.862	Aotus_nancymaae
ENSMUSG00000028911	Srsf4	92	82.035	ENSBTAG00000013309	SRSF4	92	81.681	Bos_taurus
ENSMUSG00000028911	Srsf4	92	84.199	ENSCJAG00000047192	SRSF4	93	86.638	Callithrix_jacchus
ENSMUSG00000028911	Srsf4	85	82.864	ENSCAFG00000011669	SRSF4	90	80.974	Canis_familiaris
ENSMUSG00000028911	Srsf4	85	84.198	ENSCAFG00020023963	SRSF4	88	81.882	Canis_lupus_dingo
ENSMUSG00000028911	Srsf4	92	78.571	ENSCHIG00000022096	SRSF4	85	100.000	Capra_hircus
ENSMUSG00000028911	Srsf4	92	85.991	ENSTSYG00000007903	SRSF4	93	84.267	Carlito_syrichta
ENSMUSG00000028911	Srsf4	67	78.761	ENSCCAG00000033585	SRSF4	90	82.111	Cebus_capucinus
ENSMUSG00000028911	Srsf4	92	84.430	ENSCATG00000031440	SRSF4	93	84.199	Cercocebus_atys
ENSMUSG00000028911	Srsf4	92	83.550	ENSCLAG00000009008	SRSF4	93	82.900	Chinchilla_lanigera
ENSMUSG00000028911	Srsf4	92	84.430	ENSCSAG00000001022	SRSF4	93	84.199	Chlorocebus_sabaeus
ENSMUSG00000028911	Srsf4	85	79.621	ENSCHOG00000013858	SRSF4	93	78.638	Choloepus_hoffmanni
ENSMUSG00000028911	Srsf4	67	88.554	ENSCPBG00000009020	SRSF4	93	77.897	Chrysemys_picta_bellii
ENSMUSG00000028911	Srsf4	92	84.430	ENSCANG00000028667	SRSF4	93	84.199	Colobus_angolensis_palliatus
ENSMUSG00000028911	Srsf4	92	93.172	ENSCGRG00001021115	Srsf4	92	92.105	Cricetulus_griseus_chok1gshd
ENSMUSG00000028911	Srsf4	85	91.429	ENSCGRG00000014137	Srsf4	92	91.429	Cricetulus_griseus_crigri
ENSMUSG00000028911	Srsf4	92	80.426	ENSDNOG00000047961	SRSF4	93	84.746	Dasypus_novemcinctus
ENSMUSG00000028911	Srsf4	82	100.000	ENSETEG00000009774	SRSF4	93	70.043	Echinops_telfairi
ENSMUSG00000028911	Srsf4	92	85.281	ENSEASG00005010168	SRSF4	93	87.284	Equus_asinus_asinus
ENSMUSG00000028911	Srsf4	92	85.281	ENSECAG00000021350	SRSF4	93	87.284	Equus_caballus
ENSMUSG00000028911	Srsf4	68	91.317	ENSEEUG00000008479	SRSF4	92	82.609	Erinaceus_europaeus
ENSMUSG00000028911	Srsf4	53	56.146	ENSELUG00000017551	srsf4	93	72.308	Esox_lucius
ENSMUSG00000028911	Srsf4	92	82.018	ENSFCAG00000027821	SRSF4	92	82.174	Felis_catus
ENSMUSG00000028911	Srsf4	92	72.185	ENSFALG00000001346	SRSF4	92	71.366	Ficedula_albicollis
ENSMUSG00000028911	Srsf4	61	82.333	ENSFDAG00000007332	SRSF4	92	77.986	Fukomys_damarensis
ENSMUSG00000028911	Srsf4	52	68.110	ENSFHEG00000007472	srsf4	90	86.905	Fundulus_heteroclitus
ENSMUSG00000028911	Srsf4	92	71.523	ENSGALG00000050314	SRSF4	92	71.366	Gallus_gallus
ENSMUSG00000028911	Srsf4	51	61.328	ENSGAFG00000018496	srsf4	75	85.507	Gambusia_affinis
ENSMUSG00000028911	Srsf4	67	87.576	ENSGAGG00000014836	SRSF4	93	77.137	Gopherus_agassizii
ENSMUSG00000028911	Srsf4	92	84.211	ENSGGOG00000002444	SRSF4	93	83.983	Gorilla_gorilla
ENSMUSG00000028911	Srsf4	95	76.496	ENSHGLG00000011842	SRSF4	92	79.130	Heterocephalus_glaber_female
ENSMUSG00000028911	Srsf4	95	76.496	ENSHGLG00100017279	SRSF4	92	79.130	Heterocephalus_glaber_male
ENSMUSG00000028911	Srsf4	92	83.807	ENSSTOG00000015908	SRSF4	93	86.463	Ictidomys_tridecemlineatus
ENSMUSG00000028911	Srsf4	92	71.490	ENSJJAG00000022153	Srsf4	93	73.707	Jaculus_jaculus
ENSMUSG00000028911	Srsf4	84	81.690	ENSLAFG00000002575	SRSF4	87	82.460	Loxodonta_africana
ENSMUSG00000028911	Srsf4	92	84.430	ENSMFAG00000041784	SRSF4	93	84.199	Macaca_fascicularis
ENSMUSG00000028911	Srsf4	85	83.095	ENSMMUG00000007110	SRSF4	87	82.864	Macaca_mulatta
ENSMUSG00000028911	Srsf4	92	84.430	ENSMNEG00000034931	SRSF4	93	84.199	Macaca_nemestrina
ENSMUSG00000028911	Srsf4	92	84.649	ENSMLEG00000031619	SRSF4	93	84.416	Mandrillus_leucophaeus
ENSMUSG00000028911	Srsf4	92	71.523	ENSMGAG00000002400	SRSF4	92	71.366	Meleagris_gallopavo
ENSMUSG00000028911	Srsf4	92	95.154	ENSMAUG00000021940	Srsf4	92	94.493	Mesocricetus_auratus
ENSMUSG00000028911	Srsf4	92	86.087	ENSMICG00000043567	SRSF4	93	88.528	Microcebus_murinus
ENSMUSG00000028911	Srsf4	92	89.868	ENSMOCG00000013319	Srsf4	92	92.105	Microtus_ochrogaster
ENSMUSG00000028911	Srsf4	54	65.530	ENSMMOG00000013653	srsf4	99	85.507	Mola_mola
ENSMUSG00000028911	Srsf4	61	93.355	ENSMODG00000011052	SRSF4	93	93.355	Monodelphis_domestica
ENSMUSG00000028911	Srsf4	100	99.593	MGP_CAROLIEiJ_G0026555	Srsf4	100	99.593	Mus_caroli
ENSMUSG00000028911	Srsf4	92	93.612	MGP_PahariEiJ_G0028887	Srsf4	92	93.886	Mus_pahari
ENSMUSG00000028911	Srsf4	100	99.391	MGP_SPRETEiJ_G0027535	Srsf4	100	99.391	Mus_spretus
ENSMUSG00000028911	Srsf4	92	81.466	ENSMPUG00000015470	SRSF4	93	82.796	Mustela_putorius_furo
ENSMUSG00000028911	Srsf4	67	90.578	ENSMLUG00000014770	SRSF4	92	79.310	Myotis_lucifugus
ENSMUSG00000028911	Srsf4	92	84.430	ENSNGAG00000012225	Srsf4	93	83.913	Nannospalax_galili
ENSMUSG00000028911	Srsf4	92	84.649	ENSNLEG00000009916	SRSF4	93	84.632	Nomascus_leucogenys
ENSMUSG00000028911	Srsf4	61	100.000	ENSMEUG00000003045	-	69	100.000	Notamacropus_eugenii
ENSMUSG00000028911	Srsf4	92	78.728	ENSOPRG00000010098	SRSF4	93	77.899	Ochotona_princeps
ENSMUSG00000028911	Srsf4	68	86.866	ENSODEG00000003230	SRSF4	93	80.687	Octodon_degus
ENSMUSG00000028911	Srsf4	92	78.913	ENSOCUG00000001837	SRSF4	93	81.425	Oryctolagus_cuniculus
ENSMUSG00000028911	Srsf4	92	84.868	ENSOGAG00000015515	SRSF4	92	81.739	Otolemur_garnettii
ENSMUSG00000028911	Srsf4	92	84.211	ENSPPAG00000028357	SRSF4	93	83.983	Pan_paniscus
ENSMUSG00000028911	Srsf4	92	82.018	ENSPPRG00000016248	SRSF4	92	82.174	Panthera_pardus
ENSMUSG00000028911	Srsf4	92	84.211	ENSPTRG00000000445	SRSF4	93	83.983	Pan_troglodytes
ENSMUSG00000028911	Srsf4	92	84.649	ENSPANG00000021937	SRSF4	93	84.416	Papio_anubis
ENSMUSG00000028911	Srsf4	88	90.972	ENSPEMG00000003365	Srsf4	92	94.048	Peromyscus_maniculatus_bairdii
ENSMUSG00000028911	Srsf4	92	84.649	ENSPPYG00000001629	SRSF4	93	84.416	Pongo_abelii
ENSMUSG00000028911	Srsf4	92	79.826	ENSPCAG00000009879	SRSF4	93	81.602	Procavia_capensis
ENSMUSG00000028911	Srsf4	92	84.868	ENSPCOG00000027341	SRSF4	92	84.565	Propithecus_coquereli
ENSMUSG00000028911	Srsf4	53	79.856	ENSPVAG00000012500	SRSF4	78	73.554	Pteropus_vampyrus
ENSMUSG00000028911	Srsf4	92	93.846	ENSRNOG00000010007	Srsf4	92	95.624	Rattus_norvegicus
ENSMUSG00000028911	Srsf4	92	84.430	ENSRBIG00000035789	SRSF4	93	84.199	Rhinopithecus_bieti
ENSMUSG00000028911	Srsf4	92	84.430	ENSRROG00000029463	SRSF4	93	84.199	Rhinopithecus_roxellana
ENSMUSG00000028911	Srsf4	92	84.416	ENSSBOG00000027098	SRSF4	93	86.853	Saimiri_boliviensis_boliviensis
ENSMUSG00000028911	Srsf4	57	90.357	ENSSHAG00000012407	SRSF4	94	91.209	Sarcophilus_harrisii
ENSMUSG00000028911	Srsf4	65	84.161	ENSSPUG00000015318	-	92	70.576	Sphenodon_punctatus
ENSMUSG00000028911	Srsf4	54	71.970	ENSSPAG00000014538	srsf4	88	85.507	Stegastes_partitus
ENSMUSG00000028911	Srsf4	96	80.042	ENSSSCG00000003589	SRSF4	94	83.224	Sus_scrofa
ENSMUSG00000028911	Srsf4	85	74.163	ENSTGUG00000000765	SRSF4	91	68.182	Taeniopygia_guttata
ENSMUSG00000028911	Srsf4	55	66.783	ENSTRUG00000011891	srsf4	62	80.829	Takifugu_rubripes
ENSMUSG00000028911	Srsf4	92	81.978	ENSTTRG00000002572	SRSF4	92	81.602	Tursiops_truncatus
ENSMUSG00000028911	Srsf4	92	85.870	ENSUAMG00000006106	SRSF4	93	83.297	Ursus_americanus
ENSMUSG00000028911	Srsf4	85	84.434	ENSVVUG00000012690	SRSF4	90	81.585	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0002244	hematopoietic progenitor cell differentiation	24029230.	IMP	Process
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0016607	nuclear speck	21873635.	IBA	Component
GO:0016607	nuclear speck	-	ISO	Component
GO:0045292	mRNA cis splicing, via spliceosome	21873635.	IBA	Process
GO:0048025	negative regulation of mRNA splicing, via spliceosome	-	ISO	Process
GO:1990825	sequence-specific mRNA binding	-	ISO	Function