EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000028964 (Gene tree)
Gene ID: 57320
Gene Symbol: Park7
Alias: DJ-1
Full Name: Parkinson disease (autosomal recessive%2C early onset) 7
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 17305
Position: chr4: 150897133-150914437
Accession: 2135637
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000128075	-	715	-	ENSMUSP00000115875	135 (aa)	-	A2A815
ENSMUST00000148626	-	640	-	-	- (aa)	-	-
ENSMUST00000132265	-	472	-	-	- (aa)	-	-
ENSMUST00000030805	-	908	-	ENSMUSP00000030805	189 (aa)	-	Q99LX0
ENSMUST00000134751	-	478	-	ENSMUSP00000122265	125 (aa)	-	A2A816
ENSMUST00000146184	-	584	-	ENSMUSP00000120832	84 (aa)	-	A2A817
ENSMUST00000105673	-	919	-	ENSMUSP00000101298	189 (aa)	-	Q99LX0
ENSMUST00000105674	-	937	-	ENSMUSP00000101299	189 (aa)	-	Q99LX0
ENSMUST00000105675	-	882	-	ENSMUSP00000101300	189 (aa)	-	Q99LX0
ENSMUST00000105676	-	582	-	ENSMUSP00000101301	175 (aa)	-	A2A813

Gene Model

Click here to download ENSMUSG00000028964's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu05012	Parkinson disease	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000028964's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000028964	Park7	100	95.238	ENSG00000116288	PARK7	100	91.534	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000785	chromatin	-	ISO	Component
GO:0001933	negative regulation of protein phosphorylation	-	ISO	Process
GO:0001963	synaptic transmission, dopaminergic	15799973.	IMP	Process
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	26021615.	IMP	Process
GO:0003713	transcription coactivator activity	-	ISO	Function
GO:0003723	RNA binding	11223268.	TAS	Function
GO:0003729	mRNA binding	-	ISO	Function
GO:0005102	signaling receptor binding	-	ISO	Function
GO:0005507	copper ion binding	-	ISO	Function
GO:0005515	protein binding	14752510.24947010.26021615.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	22555455.	IDA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005739	mitochondrion	18614015.	HDA	Component
GO:0005739	mitochondrion	15944198.17766438.20969476.22555455.	IDA	Component
GO:0005739	mitochondrion	-	ISO	Component
GO:0005747	mitochondrial respiratory chain complex I	-	ISO	Component
GO:0005758	mitochondrial intermembrane space	15944198.	IDA	Component
GO:0005759	mitochondrial matrix	15944198.	IDA	Component
GO:0005783	endoplasmic reticulum	22555455.	IDA	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	15944198.20969476.22555455.	IDA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005886	plasma membrane	-	IEA	Component
GO:0006281	DNA repair	-	ISO	Process
GO:0006469	negative regulation of protein kinase activity	-	ISO	Process
GO:0006508	proteolysis	-	IEA	Process
GO:0006914	autophagy	-	IEA	Process
GO:0006954	inflammatory response	-	IEA	Process
GO:0006974	cellular response to DNA damage stimulus	-	IEA	Process
GO:0006979	response to oxidative stress	-	ISO	Process
GO:0007005	mitochondrion organization	20186336.	IMP	Process
GO:0007338	single fertilization	-	IEA	Process
GO:0008134	transcription factor binding	-	ISO	Function
GO:0008233	peptidase activity	-	ISO	Function
GO:0008344	adult locomotory behavior	15721235.15799973.	IMP	Process
GO:0010273	detoxification of copper ion	23792957.	IMP	Process
GO:0010273	detoxification of copper ion	-	ISO	Process
GO:0010628	positive regulation of gene expression	22492997.	IMP	Process
GO:0010629	negative regulation of gene expression	-	ISO	Process
GO:0016020	membrane	-	IEA	Component
GO:0016532	superoxide dismutase copper chaperone activity	-	ISO	Function
GO:0016605	PML body	-	ISO	Component
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	-	ISO	Function
GO:0016787	hydrolase activity	-	IEA	Function
GO:0018323	enzyme active site formation via L-cysteine sulfinic acid	17766438.	IMP	Process
GO:0019249	lactate biosynthetic process	-	ISO	Process
GO:0019899	enzyme binding	-	ISO	Function
GO:0019900	kinase binding	-	ISO	Function
GO:0019955	cytokine binding	-	ISO	Function
GO:0030073	insulin secretion	22611253.	IMP	Process
GO:0030424	axon	-	ISO	Component
GO:0031397	negative regulation of protein ubiquitination	24899725.	IMP	Process
GO:0031397	negative regulation of protein ubiquitination	-	ISO	Process
GO:0032091	negative regulation of protein binding	-	ISO	Process
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	-	ISO	Process
GO:0032757	positive regulation of interleukin-8 production	-	ISO	Process
GO:0033138	positive regulation of peptidyl-serine phosphorylation	-	ISO	Process
GO:0033234	negative regulation of protein sumoylation	-	ISO	Process
GO:0033864	positive regulation of NAD(P)H oxidase activity	26021615.	IMP	Process
GO:0034599	cellular response to oxidative stress	21068725.	IMP	Process
GO:0034599	cellular response to oxidative stress	-	ISO	Process
GO:0034614	cellular response to reactive oxygen species	16624565.	IMP	Process
GO:0036470	tyrosine 3-monooxygenase activator activity	-	ISO	Function
GO:0036471	cellular response to glyoxal	22523093.	IMP	Process
GO:0036471	cellular response to glyoxal	-	ISO	Process
GO:0036478	L-dopa decarboxylase activator activity	-	ISO	Function
GO:0036524	protein deglycase activity	21873635.	IBA	Function
GO:0036524	protein deglycase activity	-	ISO	Function
GO:0036526	peptidyl-cysteine deglycation	-	ISO	Process
GO:0036527	peptidyl-arginine deglycation	-	ISO	Process
GO:0036528	peptidyl-lysine deglycation	-	ISO	Process
GO:0036529	protein deglycation, glyoxal removal	21873635.	IBA	Process
GO:0036529	protein deglycation, glyoxal removal	-	ISO	Process
GO:0036531	glutathione deglycation	-	ISO	Process
GO:0042177	negative regulation of protein catabolic process	24899725.	IMP	Process
GO:0042542	response to hydrogen peroxide	15784737.	IDA	Process
GO:0042542	response to hydrogen peroxide	15784737.	IMP	Process
GO:0042593	glucose homeostasis	22611253.	IMP	Process
GO:0042743	hydrogen peroxide metabolic process	17766438.	IMP	Process
GO:0042743	hydrogen peroxide metabolic process	-	ISO	Process
GO:0042802	identical protein binding	-	ISO	Function
GO:0042803	protein homodimerization activity	-	ISO	Function
GO:0043005	neuron projection	24947010.	IDA	Component
GO:0043066	negative regulation of apoptotic process	22523093.	IMP	Process
GO:0043066	negative regulation of apoptotic process	-	ISO	Process
GO:0043523	regulation of neuron apoptotic process	-	ISO	Process
GO:0043524	negative regulation of neuron apoptotic process	-	ISO	Process
GO:0044297	cell body	24947010.	IDA	Component
GO:0044388	small protein activating enzyme binding	-	ISO	Function
GO:0044390	ubiquitin-like protein conjugating enzyme binding	-	ISO	Function
GO:0045121	membrane raft	-	ISO	Component
GO:0045340	mercury ion binding	-	ISO	Function
GO:0045944	positive regulation of transcription by RNA polymerase II	17015834.21097510.	IMP	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	-	ISO	Process
GO:0046295	glycolate biosynthetic process	22523093.	IDA	Process
GO:0046295	glycolate biosynthetic process	-	ISO	Process
GO:0046826	negative regulation of protein export from nucleus	-	ISO	Process
GO:0048471	perinuclear region of cytoplasm	-	ISO	Component
GO:0050681	androgen receptor binding	-	ISO	Function
GO:0050727	regulation of inflammatory response	19276172.	IMP	Process
GO:0050787	detoxification of mercury ion	23792957.	IMP	Process
GO:0050787	detoxification of mercury ion	-	ISO	Process
GO:0050821	protein stabilization	17015834.19229105.	IMP	Process
GO:0050821	protein stabilization	-	ISO	Process
GO:0051091	positive regulation of DNA-binding transcription factor activity	-	ISO	Process
GO:0051444	negative regulation of ubiquitin-protein transferase activity	24899725.	IC	Process
GO:0051444	negative regulation of ubiquitin-protein transferase activity	-	ISO	Process
GO:0051583	dopamine uptake involved in synaptic transmission	15721235.	IMP	Process
GO:0051881	regulation of mitochondrial membrane potential	-	ISO	Process
GO:0051899	membrane depolarization	16624565.	IMP	Process
GO:0051920	peroxiredoxin activity	17766438.	IMP	Function
GO:0060081	membrane hyperpolarization	16624565.	IMP	Process
GO:0060548	negative regulation of cell death	15784737.	IMP	Process
GO:0060548	negative regulation of cell death	-	ISO	Process
GO:0060765	regulation of androgen receptor signaling pathway	-	ISO	Process
GO:0061827	sperm head	-	ISO	Component
GO:0070301	cellular response to hydrogen peroxide	15784737.	IMP	Process
GO:0070301	cellular response to hydrogen peroxide	-	ISO	Process
GO:0070491	repressing transcription factor binding	-	ISO	Function
GO:0090073	positive regulation of protein homodimerization activity	-	ISO	Process
GO:0097110	scaffold protein binding	-	ISO	Function
GO:0106044	guanine deglycation	-	ISO	Process
GO:0106045	guanine deglycation, methylglyoxal removal	-	ISO	Process
GO:0106046	guanine deglycation, glyoxal removal	21873635.	IBA	Process
GO:0106046	guanine deglycation, glyoxal removal	-	ISO	Process
GO:1900182	positive regulation of protein localization to nucleus	-	ISO	Process
GO:1901215	negative regulation of neuron death	-	ISO	Process
GO:1901671	positive regulation of superoxide dismutase activity	-	ISO	Process
GO:1901984	negative regulation of protein acetylation	-	ISO	Process
GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	22555455.	IMP	Process
GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	14652021.	IMP	Process
GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	-	ISO	Process
GO:1902958	positive regulation of mitochondrial electron transport, NADH to ubiquinone	19822128.	IMP	Process
GO:1902958	positive regulation of mitochondrial electron transport, NADH to ubiquinone	-	ISO	Process
GO:1903094	negative regulation of protein K48-linked deubiquitination	-	ISO	Process
GO:1903122	negative regulation of TRAIL-activated apoptotic signaling pathway	-	ISO	Process
GO:1903135	cupric ion binding	-	ISO	Function
GO:1903136	cuprous ion binding	-	ISO	Function
GO:1903168	positive regulation of pyrroline-5-carboxylate reductase activity	-	ISO	Process
GO:1903178	positive regulation of tyrosine 3-monooxygenase activity	-	ISO	Process
GO:1903181	positive regulation of dopamine biosynthetic process	-	ISO	Process
GO:1903189	glyoxal metabolic process	22523093.	IDA	Process
GO:1903189	glyoxal metabolic process	-	ISO	Process
GO:1903197	positive regulation of L-dopa biosynthetic process	-	ISO	Process
GO:1903200	positive regulation of L-dopa decarboxylase activity	-	ISO	Process
GO:1903202	negative regulation of oxidative stress-induced cell death	-	ISO	Process
GO:1903204	negative regulation of oxidative stress-induced neuron death	24899725.	IMP	Process
GO:1903206	negative regulation of hydrogen peroxide-induced cell death	-	ISO	Process
GO:1903208	negative regulation of hydrogen peroxide-induced neuron death	24947010.	IMP	Process
GO:1903208	negative regulation of hydrogen peroxide-induced neuron death	-	ISO	Process
GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	-	ISO	Process
GO:1903384	negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	14652021.	IMP	Process
GO:1903384	negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	-	ISO	Process
GO:1903427	negative regulation of reactive oxygen species biosynthetic process	22611253.	IMP	Process
GO:1903428	positive regulation of reactive oxygen species biosynthetic process	22555455.	IDA	Process
GO:1904782	negative regulation of NMDA glutamate receptor activity	-	ISO	Process
GO:1905259	negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	-	ISO	Process
GO:1905516	positive regulation of fertilization	-	ISO	Process
GO:1990381	ubiquitin-specific protease binding	-	ISO	Function
GO:2000157	negative regulation of ubiquitin-specific protease activity	-	ISO	Process
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	21068725.	IMP	Process
GO:2000679	positive regulation of transcription regulatory region DNA binding	-	ISO	Process
GO:2000825	positive regulation of androgen receptor activity	-	ISO	Process
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	-	ISO	Process
GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	-	ISO	Process