EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000030056 (Gene tree)
Gene ID: 57905
Gene Symbol: Isy1
Alias: 5830446M03Rik
Full Name: ISY1 splicing factor homolog
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Minus strand
Length: 24530 bases
Position: chr6:87814269-87838798
Accession: 1923310
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000086923	Isy1	PF06246.12	3.2e-98	1	1
ENSMUSP00000145001	Isy1	PF06246.12	1.1e-32	1	2
ENSMUSP00000145001	Isy1	PF06246.12	1.1e-32	2	2

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000089497	-	5837	-	ENSMUSP00000086923	285 (aa)	-	Q69ZQ2
ENSMUST00000204892	-	394	-	-	- (aa)	-	-
ENSMUST00000204431	-	387	-	ENSMUSP00000145001	95 (aa)	-	A0A0N4SV90
ENSMUST00000204421	-	916	-	-	- (aa)	-	-
ENSMUST00000205070	-	500	-	ENSMUSP00000144956	50 (aa)	-	A0A0N4SV52
ENSMUST00000204310	-	643	-	-	- (aa)	-	-
ENSMUST00000204881	-	751	-	ENSMUSP00000144710	150 (aa)	-	A0A0N4SUJ7
ENSMUST00000203429	-	267	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000030056's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03040	Spliceosome	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000030056's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000030056	Isy1	99	98.239	ENSG00000261796	ISY1-RAB43	86	98.239	Homo_sapiens
ENSMUSG00000030056	Isy1	100	98.246	ENSG00000240682	ISY1	100	98.246	Homo_sapiens
ENSMUSG00000030056	Isy1	99	98.233	ENSAMEG00000015341	-	86	98.233	Ailuropoda_melanoleuca
ENSMUSG00000030056	Isy1	96	95.833	ENSACIG00000014723	isy1	74	88.587	Amphilophus_citrinellus
ENSMUSG00000030056	Isy1	98	95.918	ENSAOCG00000007147	isy1	99	77.544	Amphiprion_ocellaris
ENSMUSG00000030056	Isy1	98	95.918	ENSAPEG00000021883	isy1	99	69.182	Amphiprion_percula
ENSMUSG00000030056	Isy1	80	78.947	ENSATEG00000009521	isy1	84	74.510	Anabas_testudineus
ENSMUSG00000030056	Isy1	96	83.673	ENSAPLG00000014136	-	99	76.923	Anas_platyrhynchos
ENSMUSG00000030056	Isy1	91	88.372	ENSACAG00000013166	-	99	87.984	Anolis_carolinensis
ENSMUSG00000030056	Isy1	100	97.895	ENSANAG00000027120	-	100	97.895	Aotus_nancymaae
ENSMUSG00000030056	Isy1	98	81.633	ENSACLG00000014430	isy1	99	71.528	Astatotilapia_calliptera
ENSMUSG00000030056	Isy1	98	95.918	ENSAMXG00000005423	isy1	99	84.561	Astyanax_mexicanus
ENSMUSG00000030056	Isy1	98	97.959	ENSBTAG00000030915	ISY1	99	94.718	Bos_taurus
ENSMUSG00000030056	Isy1	100	51.923	WBGene00009966	isy-1	99	50.368	Caenorhabditis_elegans
ENSMUSG00000030056	Isy1	100	97.895	ENSCJAG00000017419	-	100	97.895	Callithrix_jacchus
ENSMUSG00000030056	Isy1	100	98.596	ENSCAFG00000004333	ISY1	100	98.596	Canis_familiaris
ENSMUSG00000030056	Isy1	100	98.596	ENSCAFG00020004867	-	100	98.596	Canis_lupus_dingo
ENSMUSG00000030056	Isy1	98	97.959	ENSCHIG00000008237	-	99	94.718	Capra_hircus
ENSMUSG00000030056	Isy1	100	97.895	ENSTSYG00000013897	-	100	97.895	Carlito_syrichta
ENSMUSG00000030056	Isy1	86	97.674	ENSCAPG00000016359	-	100	73.118	Cavia_aperea
ENSMUSG00000030056	Isy1	100	98.947	ENSCPOG00000014735	-	100	98.947	Cavia_porcellus
ENSMUSG00000030056	Isy1	100	98.246	ENSCCAG00000028517	-	100	98.246	Cebus_capucinus
ENSMUSG00000030056	Isy1	100	98.596	ENSCATG00000030672	-	100	98.596	Cercocebus_atys
ENSMUSG00000030056	Isy1	100	98.601	ENSCLAG00000007518	-	100	98.601	Chinchilla_lanigera
ENSMUSG00000030056	Isy1	100	98.596	ENSCSAG00000008798	-	100	98.596	Chlorocebus_sabaeus
ENSMUSG00000030056	Isy1	98	95.918	ENSCPBG00000026346	-	99	90.141	Chrysemys_picta_bellii
ENSMUSG00000030056	Isy1	96	70.833	ENSCING00000000716	-	99	63.860	Ciona_intestinalis
ENSMUSG00000030056	Isy1	98	71.429	ENSCSAVG00000008992	-	99	64.014	Ciona_savignyi
ENSMUSG00000030056	Isy1	100	98.596	ENSCANG00000037761	-	100	98.596	Colobus_angolensis_palliatus
ENSMUSG00000030056	Isy1	100	98.596	ENSCGRG00001003415	Isy1	100	98.596	Cricetulus_griseus_chok1gshd
ENSMUSG00000030056	Isy1	100	98.596	ENSCGRG00000011641	Isy1	100	98.596	Cricetulus_griseus_crigri
ENSMUSG00000030056	Isy1	98	95.918	ENSCSEG00000020382	isy1	95	72.112	Cynoglossus_semilaevis
ENSMUSG00000030056	Isy1	98	95.918	ENSCVAG00000000650	isy1	99	78.246	Cyprinodon_variegatus
ENSMUSG00000030056	Isy1	98	93.878	ENSDARG00000063466	isy1	99	83.158	Danio_rerio
ENSMUSG00000030056	Isy1	100	96.503	ENSDNOG00000002763	-	100	96.503	Dasypus_novemcinctus
ENSMUSG00000030056	Isy1	97	98.195	ENSDORG00000006886	Isy1	100	98.195	Dipodomys_ordii
ENSMUSG00000030056	Isy1	100	65.263	FBgn0037550	CG9667	99	61.455	Drosophila_melanogaster
ENSMUSG00000030056	Isy1	96	97.080	ENSETEG00000017009	-	100	97.080	Echinops_telfairi
ENSMUSG00000030056	Isy1	52	74.242	ENSEBUG00000002888	isy1	70	74.242	Eptatretus_burgeri
ENSMUSG00000030056	Isy1	97	95.307	ENSEASG00005015810	-	97	95.307	Equus_asinus_asinus
ENSMUSG00000030056	Isy1	98	97.959	ENSECAG00000013768	-	88	99.254	Equus_caballus
ENSMUSG00000030056	Isy1	98	91.837	ENSELUG00000000489	isy1	99	85.664	Esox_lucius
ENSMUSG00000030056	Isy1	100	98.596	ENSFCAG00000008664	-	100	98.596	Felis_catus
ENSMUSG00000030056	Isy1	98	95.918	ENSFALG00000000023	-	99	89.085	Ficedula_albicollis
ENSMUSG00000030056	Isy1	98	89.796	ENSFALG00000014998	-	100	82.456	Ficedula_albicollis
ENSMUSG00000030056	Isy1	97	98.201	ENSFDAG00000012661	-	95	98.201	Fukomys_damarensis
ENSMUSG00000030056	Isy1	98	95.918	ENSFHEG00000006776	isy1	99	78.246	Fundulus_heteroclitus
ENSMUSG00000030056	Isy1	75	85.294	ENSGMOG00000005635	isy1	73	85.294	Gadus_morhua
ENSMUSG00000030056	Isy1	98	95.918	ENSGALG00000005012	-	99	89.789	Gallus_gallus
ENSMUSG00000030056	Isy1	96	93.750	ENSGAFG00000019550	isy1	99	75.972	Gambusia_affinis
ENSMUSG00000030056	Isy1	98	95.918	ENSGACG00000003342	isy1	99	78.246	Gasterosteus_aculeatus
ENSMUSG00000030056	Isy1	96	88.727	ENSGAGG00000021274	-	97	88.372	Gopherus_agassizii
ENSMUSG00000030056	Isy1	100	98.246	ENSGGOG00000038733	ISY1	100	98.246	Gorilla_gorilla
ENSMUSG00000030056	Isy1	98	81.633	ENSHBUG00000008922	-	92	65.909	Haplochromis_burtoni
ENSMUSG00000030056	Isy1	100	98.246	ENSHGLG00000002576	-	100	98.246	Heterocephalus_glaber_female
ENSMUSG00000030056	Isy1	100	84.000	ENSHGLG00000017889	-	79	79.359	Heterocephalus_glaber_female
ENSMUSG00000030056	Isy1	99	96.154	ENSHGLG00100004254	-	99	96.154	Heterocephalus_glaber_male
ENSMUSG00000030056	Isy1	100	84.000	ENSHGLG00100005531	-	79	79.359	Heterocephalus_glaber_male
ENSMUSG00000030056	Isy1	96	93.750	ENSHCOG00000014775	isy1	99	72.438	Hippocampus_comes
ENSMUSG00000030056	Isy1	98	93.878	ENSIPUG00000011379	Isy1	99	84.507	Ictalurus_punctatus
ENSMUSG00000030056	Isy1	99	97.544	ENSSTOG00000024769	-	100	97.544	Ictidomys_tridecemlineatus
ENSMUSG00000030056	Isy1	78	98.655	ENSJJAG00000009635	Isy1	96	98.655	Jaculus_jaculus
ENSMUSG00000030056	Isy1	98	93.878	ENSLACG00000004490	isy1	99	87.676	Latimeria_chalumnae
ENSMUSG00000030056	Isy1	98	91.837	ENSLOCG00000013988	isy1	99	85.263	Lepisosteus_oculatus
ENSMUSG00000030056	Isy1	96	97.917	ENSLAFG00000004015	-	100	88.028	Loxodonta_africana
ENSMUSG00000030056	Isy1	100	98.596	ENSMFAG00000037074	-	100	98.596	Macaca_fascicularis
ENSMUSG00000030056	Isy1	100	98.596	ENSMMUG00000011580	ISY1-RAB43	100	98.596	Macaca_mulatta
ENSMUSG00000030056	Isy1	96	97.917	ENSMNEG00000043206	ISY1	99	91.197	Macaca_nemestrina
ENSMUSG00000030056	Isy1	100	98.596	ENSMLEG00000033836	-	100	98.596	Mandrillus_leucophaeus
ENSMUSG00000030056	Isy1	98	93.878	ENSMAMG00000009501	isy1	99	79.225	Mastacembelus_armatus
ENSMUSG00000030056	Isy1	98	95.918	ENSMZEG00005012021	isy1	99	79.225	Maylandia_zebra
ENSMUSG00000030056	Isy1	96	95.833	ENSMGAG00000005181	-	99	89.085	Meleagris_gallopavo
ENSMUSG00000030056	Isy1	100	98.596	ENSMAUG00000008793	Isy1	100	98.596	Mesocricetus_auratus
ENSMUSG00000030056	Isy1	97	95.290	ENSMICG00000037547	-	100	95.290	Microcebus_murinus
ENSMUSG00000030056	Isy1	100	99.298	ENSMOCG00000000472	Isy1	100	99.298	Microtus_ochrogaster
ENSMUSG00000030056	Isy1	99	70.690	ENSMMOG00000017810	isy1	99	70.690	Mola_mola
ENSMUSG00000030056	Isy1	98	95.918	ENSMODG00000008387	-	100	91.228	Monodelphis_domestica
ENSMUSG00000030056	Isy1	98	93.878	ENSMALG00000020650	isy1	99	78.947	Monopterus_albus
ENSMUSG00000030056	Isy1	100	100.000	MGP_CAROLIEiJ_G0028619	Isy1	100	100.000	Mus_caroli
ENSMUSG00000030056	Isy1	98	97.959	MGP_PahariEiJ_G0022357	Isy1	100	86.713	Mus_pahari
ENSMUSG00000030056	Isy1	100	100.000	MGP_SPRETEiJ_G0029631	Isy1	100	100.000	Mus_spretus
ENSMUSG00000030056	Isy1	98	97.959	ENSMPUG00000017307	-	95	88.732	Mustela_putorius_furo
ENSMUSG00000030056	Isy1	96	97.917	ENSMLUG00000011804	-	100	92.958	Myotis_lucifugus
ENSMUSG00000030056	Isy1	100	99.649	ENSNGAG00000015207	Isy1	100	99.649	Nannospalax_galili
ENSMUSG00000030056	Isy1	98	81.633	ENSNBRG00000006974	isy1	75	85.556	Neolamprologus_brichardi
ENSMUSG00000030056	Isy1	100	98.596	ENSNLEG00000028747	ISY1	100	98.596	Nomascus_leucogenys
ENSMUSG00000030056	Isy1	78	97.436	ENSMEUG00000008434	-	78	87.692	Notamacropus_eugenii
ENSMUSG00000030056	Isy1	99	97.173	ENSOPRG00000005468	-	85	97.173	Ochotona_princeps
ENSMUSG00000030056	Isy1	97	85.612	ENSODEG00000002067	-	96	85.971	Octodon_degus
ENSMUSG00000030056	Isy1	98	81.633	ENSONIG00000000267	isy1	100	75.794	Oreochromis_niloticus
ENSMUSG00000030056	Isy1	99	80.783	ENSOANG00000013141	-	99	80.071	Ornithorhynchus_anatinus
ENSMUSG00000030056	Isy1	100	98.596	ENSOCUG00000003923	-	100	98.596	Oryctolagus_cuniculus
ENSMUSG00000030056	Isy1	98	95.918	ENSORLG00000013250	isy1	99	76.842	Oryzias_latipes
ENSMUSG00000030056	Isy1	98	95.918	ENSORLG00020020966	isy1	99	76.491	Oryzias_latipes_hni
ENSMUSG00000030056	Isy1	98	95.918	ENSORLG00015017316	isy1	99	76.842	Oryzias_latipes_hsok
ENSMUSG00000030056	Isy1	96	93.750	ENSOMEG00000023905	isy1	99	75.874	Oryzias_melastigma
ENSMUSG00000030056	Isy1	99	98.944	ENSOGAG00000005142	-	99	98.944	Otolemur_garnettii
ENSMUSG00000030056	Isy1	98	95.918	ENSOARG00000003231	-	94	91.197	Ovis_aries
ENSMUSG00000030056	Isy1	100	97.895	ENSPPAG00000042141	-	100	97.895	Pan_paniscus
ENSMUSG00000030056	Isy1	100	98.596	ENSPPRG00000003480	-	100	98.596	Panthera_pardus
ENSMUSG00000030056	Isy1	100	98.596	ENSPTIG00000017919	-	100	98.596	Panthera_tigris_altaica
ENSMUSG00000030056	Isy1	98	97.959	ENSPTRG00000015367	ISY1	100	90.554	Pan_troglodytes
ENSMUSG00000030056	Isy1	100	98.246	ENSPANG00000004750	-	100	98.246	Papio_anubis
ENSMUSG00000030056	Isy1	98	95.918	ENSPKIG00000024592	isy1	99	85.563	Paramormyrops_kingsleyae
ENSMUSG00000030056	Isy1	98	95.918	ENSPSIG00000009384	-	99	88.732	Pelodiscus_sinensis
ENSMUSG00000030056	Isy1	82	90.244	ENSPMGG00000016328	isy1	88	64.364	Periophthalmus_magnuspinnatus
ENSMUSG00000030056	Isy1	100	98.947	ENSPEMG00000005390	Isy1	100	98.947	Peromyscus_maniculatus_bairdii
ENSMUSG00000030056	Isy1	96	87.500	ENSPMAG00000005010	-	99	85.475	Petromyzon_marinus
ENSMUSG00000030056	Isy1	98	95.918	ENSPCIG00000000466	-	74	91.228	Phascolarctos_cinereus
ENSMUSG00000030056	Isy1	63	67.039	ENSPFOG00000010228	isy1	99	68.333	Poecilia_formosa
ENSMUSG00000030056	Isy1	96	93.750	ENSPREG00000015121	isy1	99	70.714	Poecilia_reticulata
ENSMUSG00000030056	Isy1	100	98.596	ENSPPYG00000013424	-	100	98.596	Pongo_abelii
ENSMUSG00000030056	Isy1	99	88.235	ENSPCAG00000009535	-	100	88.235	Procavia_capensis
ENSMUSG00000030056	Isy1	98	97.959	ENSPCOG00000025242	-	100	100.000	Propithecus_coquereli
ENSMUSG00000030056	Isy1	98	95.918	ENSPNAG00000000703	isy1	99	84.561	Pygocentrus_nattereri
ENSMUSG00000030056	Isy1	100	98.947	ENSRNOG00000010021	Isy1	100	98.947	Rattus_norvegicus
ENSMUSG00000030056	Isy1	98	97.959	ENSRBIG00000028747	ISY1	100	84.561	Rhinopithecus_bieti
ENSMUSG00000030056	Isy1	100	98.596	ENSRROG00000032314	ISY1	100	98.596	Rhinopithecus_roxellana
ENSMUSG00000030056	Isy1	100	32.000	YJR050W	ISY1	61	33.333	Saccharomyces_cerevisiae
ENSMUSG00000030056	Isy1	100	98.246	ENSSBOG00000029301	-	100	98.246	Saimiri_boliviensis_boliviensis
ENSMUSG00000030056	Isy1	98	95.918	ENSSHAG00000017192	-	100	91.228	Sarcophilus_harrisii
ENSMUSG00000030056	Isy1	98	95.918	ENSSFOG00015001127	isy1	99	84.912	Scleropages_formosus
ENSMUSG00000030056	Isy1	98	93.878	ENSSMAG00000006601	isy1	99	78.246	Scophthalmus_maximus
ENSMUSG00000030056	Isy1	98	95.918	ENSSDUG00000018291	isy1	99	79.649	Seriola_dumerili
ENSMUSG00000030056	Isy1	98	95.918	ENSSLDG00000022252	isy1	99	79.298	Seriola_lalandi_dorsalis
ENSMUSG00000030056	Isy1	64	73.224	ENSSARG00000007648	-	67	73.224	Sorex_araneus
ENSMUSG00000030056	Isy1	98	95.918	ENSSPUG00000018050	-	99	89.789	Sphenodon_punctatus
ENSMUSG00000030056	Isy1	80	95.000	ENSSPAG00000021900	isy1	63	89.474	Stegastes_partitus
ENSMUSG00000030056	Isy1	100	98.246	ENSSSCG00000038900	-	100	98.246	Sus_scrofa
ENSMUSG00000030056	Isy1	78	85.068	ENSTGUG00000003998	-	99	85.068	Taeniopygia_guttata
ENSMUSG00000030056	Isy1	98	93.878	ENSTGUG00000007076	-	100	86.441	Taeniopygia_guttata
ENSMUSG00000030056	Isy1	98	93.878	ENSTRUG00000002546	isy1	96	87.778	Takifugu_rubripes
ENSMUSG00000030056	Isy1	96	95.833	ENSTNIG00000005224	isy1	99	73.356	Tetraodon_nigroviridis
ENSMUSG00000030056	Isy1	77	77.273	ENSTBEG00000006938	-	100	77.273	Tupaia_belangeri
ENSMUSG00000030056	Isy1	99	92.606	ENSTTRG00000015267	-	100	92.606	Tursiops_truncatus
ENSMUSG00000030056	Isy1	80	97.500	ENSUAMG00000018980	-	81	100.000	Ursus_americanus
ENSMUSG00000030056	Isy1	78	81.081	ENSVPAG00000015390	-	63	100.000	Vicugna_pacos
ENSMUSG00000030056	Isy1	100	98.596	ENSVVUG00000018261	-	100	98.596	Vulpes_vulpes
ENSMUSG00000030056	Isy1	80	95.000	ENSXETG00000018921	isy1	100	96.923	Xenopus_tropicalis
ENSMUSG00000030056	Isy1	96	95.833	ENSXCOG00000017248	isy1	89	95.146	Xiphophorus_couchianus
ENSMUSG00000030056	Isy1	98	95.918	ENSXMAG00000012452	isy1	99	77.895	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000350	generation of catalytic spliceosome for second transesterification step	21873635.	IBA	Process
GO:0000384	first spliceosomal transesterification activity	21873635.	IBA	Function
GO:0000389	mRNA 3'-splice site recognition	21873635.	IBA	Process
GO:0000974	Prp19 complex	21873635.	IBA	Component
GO:0005634	nucleus	-	IEA	Component
GO:0005681	spliceosomal complex	-	IEA	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0071013	catalytic step 2 spliceosome	21873635.	IBA	Component
GO:0071014	post-mRNA release spliceosomal complex	21873635.	IBA	Component
GO:0071020	post-spliceosomal complex	21873635.	IBA	Component