EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000030400 (Gene tree)
Gene ID: 13871
Gene Symbol: Ercc2
Alias: Ercc-2|Mhdarco15|RCO015|XPD
Full Name: excision repair cross-complementing rodent repair deficiency%2C complementation group 2
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Plus strand
Length: 13685 bases
Position: chr7:19382010-19395694
Accession: 95413
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000117840	ResIII	PF04851.15	2.8e-07	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000136055	-	311	-	-	- (aa)	-	-
ENSMUST00000135693	-	994	-	-	- (aa)	-	-
ENSMUST00000127363	-	607	-	-	- (aa)	-	-
ENSMUST00000129249	-	2071	-	ENSMUSP00000117840	684 (aa)	-	F6YA33
ENSMUST00000145039	-	286	-	-	- (aa)	-	-
ENSMUST00000128167	-	684	-	-	- (aa)	-	-
ENSMUST00000062831	-	3578	-	ENSMUSP00000054380	760 (aa)	-	O08811
ENSMUST00000129291	-	485	-	-	- (aa)	-	-
ENSMUST00000108460	-	3485	-	ENSMUSP00000104100	739 (aa)	-	E9Q6K1
ENSMUST00000108461	-	2799	-	ENSMUSP00000104101	508 (aa)	-	D3Z700

Gene Model

Click here to download ENSMUSG00000030400's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03022	Basal transcription factors	KEGG
mmu03420	Nucleotide excision repair	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000030400's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000030400	Ercc2	99	97.944	ENSG00000104884	ERCC2	99	98.010	Homo_sapiens
ENSMUSG00000030400	Ercc2	97	85.068	ENSAPOG00000000375	ercc2	99	85.068	Acanthochromis_polyacanthus
ENSMUSG00000030400	Ercc2	99	85.272	ENSACIG00000008002	ercc2	99	85.272	Amphilophus_citrinellus
ENSMUSG00000030400	Ercc2	97	83.634	ENSAOCG00000016153	ercc2	99	83.634	Amphiprion_ocellaris
ENSMUSG00000030400	Ercc2	97	83.634	ENSAPEG00000016712	ercc2	99	83.634	Amphiprion_percula
ENSMUSG00000030400	Ercc2	99	85.294	ENSATEG00000005268	ercc2	99	85.294	Anabas_testudineus
ENSMUSG00000030400	Ercc2	99	97.797	ENSANAG00000022694	ERCC2	99	97.797	Aotus_nancymaae
ENSMUSG00000030400	Ercc2	97	85.671	ENSACLG00000017573	ercc2	99	85.671	Astatotilapia_calliptera
ENSMUSG00000030400	Ercc2	97	85.693	ENSAMXG00000009052	ercc2	99	85.693	Astyanax_mexicanus
ENSMUSG00000030400	Ercc2	99	98.091	ENSCJAG00000012716	ERCC2	99	98.091	Callithrix_jacchus
ENSMUSG00000030400	Ercc2	99	98.088	ENSCAFG00020011390	ERCC2	99	98.088	Canis_lupus_dingo
ENSMUSG00000030400	Ercc2	96	80.758	ENSTSYG00000026723	ERCC2	99	80.758	Carlito_syrichta
ENSMUSG00000030400	Ercc2	99	95.328	ENSCCAG00000019831	ERCC2	99	95.328	Cebus_capucinus
ENSMUSG00000030400	Ercc2	99	98.091	ENSCANG00000040683	ERCC2	99	98.091	Colobus_angolensis_palliatus
ENSMUSG00000030400	Ercc2	97	80.422	ENSCSEG00000006041	ercc2	99	80.422	Cynoglossus_semilaevis
ENSMUSG00000030400	Ercc2	99	94.853	ENSEASG00005013856	ERCC2	99	94.853	Equus_asinus_asinus
ENSMUSG00000030400	Ercc2	97	84.511	ENSELUG00000018055	ercc2	100	84.511	Esox_lucius
ENSMUSG00000030400	Ercc2	99	97.944	ENSFCAG00000002679	ERCC2	99	97.944	Felis_catus
ENSMUSG00000030400	Ercc2	99	85.441	ENSFHEG00000000072	ercc2	99	85.441	Fundulus_heteroclitus
ENSMUSG00000030400	Ercc2	99	84.167	ENSGAGG00000009493	ERCC2	99	84.167	Gopherus_agassizii
ENSMUSG00000030400	Ercc2	99	98.091	ENSGGOG00000015842	ERCC2	99	98.091	Gorilla_gorilla
ENSMUSG00000030400	Ercc2	97	84.858	ENSHBUG00000002187	ercc2	99	84.858	Haplochromis_burtoni
ENSMUSG00000030400	Ercc2	99	84.265	ENSLBEG00000010573	ercc2	92	84.265	Labrus_bergylta
ENSMUSG00000030400	Ercc2	99	98.091	ENSMFAG00000037898	ERCC2	99	98.091	Macaca_fascicularis
ENSMUSG00000030400	Ercc2	99	98.091	ENSMMUG00000014419	ERCC2	99	98.091	Macaca_mulatta
ENSMUSG00000030400	Ercc2	99	98.091	ENSMNEG00000042641	ERCC2	99	98.091	Macaca_nemestrina
ENSMUSG00000030400	Ercc2	82	39.655	ENSMNEG00000040728	BRIP1	57	39.655	Macaca_nemestrina
ENSMUSG00000030400	Ercc2	99	98.085	ENSMLEG00000043492	ERCC2	99	98.085	Mandrillus_leucophaeus
ENSMUSG00000030400	Ercc2	99	85.125	ENSMAMG00000016724	ercc2	99	85.125	Mastacembelus_armatus
ENSMUSG00000030400	Ercc2	97	85.693	ENSMZEG00005024441	ercc2	99	85.693	Maylandia_zebra
ENSMUSG00000030400	Ercc2	99	97.651	ENSMICG00000000635	ERCC2	99	97.651	Microcebus_murinus
ENSMUSG00000030400	Ercc2	99	81.591	ENSMMOG00000005162	ercc2	99	81.738	Mola_mola
ENSMUSG00000030400	Ercc2	99	84.242	ENSMALG00000005990	ercc2	99	84.242	Monopterus_albus
ENSMUSG00000030400	Ercc2	99	100.000	MGP_CAROLIEiJ_G0029287	Ercc2	100	100.000	Mus_caroli
ENSMUSG00000030400	Ercc2	99	100.000	MGP_PahariEiJ_G0021147	Ercc2	100	100.000	Mus_pahari
ENSMUSG00000030400	Ercc2	99	99.854	MGP_SPRETEiJ_G0030371	Ercc2	100	99.854	Mus_spretus
ENSMUSG00000030400	Ercc2	99	98.091	ENSPPAG00000044005	ERCC2	99	98.091	Pan_paniscus
ENSMUSG00000030400	Ercc2	99	92.647	ENSPPRG00000000507	ERCC2	99	93.235	Panthera_pardus
ENSMUSG00000030400	Ercc2	99	98.091	ENSPTRG00000011149	ERCC2	99	98.091	Pan_troglodytes
ENSMUSG00000030400	Ercc2	99	98.085	ENSPANG00000032195	ERCC2	99	98.085	Papio_anubis
ENSMUSG00000030400	Ercc2	99	80.735	ENSPKIG00000006883	ercc2	98	80.735	Paramormyrops_kingsleyae
ENSMUSG00000030400	Ercc2	97	84.789	ENSPMGG00000000223	ercc2	99	84.789	Periophthalmus_magnuspinnatus
ENSMUSG00000030400	Ercc2	99	85.441	ENSPLAG00000002626	ercc2	99	85.441	Poecilia_latipinna
ENSMUSG00000030400	Ercc2	99	85.441	ENSPMEG00000002858	ercc2	99	85.441	Poecilia_mexicana
ENSMUSG00000030400	Ercc2	99	80.882	ENSPREG00000019280	ercc2	99	80.882	Poecilia_reticulata
ENSMUSG00000030400	Ercc2	97	84.985	ENSPNYG00000022007	ercc2	99	84.985	Pundamilia_nyererei
ENSMUSG00000030400	Ercc2	97	84.962	ENSPNAG00000010434	ercc2	100	84.962	Pygocentrus_nattereri
ENSMUSG00000030400	Ercc2	99	98.091	ENSRROG00000040423	ERCC2	99	98.091	Rhinopithecus_roxellana
ENSMUSG00000030400	Ercc2	99	98.382	ENSSBOG00000030257	ERCC2	99	98.382	Saimiri_boliviensis_boliviensis
ENSMUSG00000030400	Ercc2	97	79.310	ENSSMAG00000019720	ercc2	99	79.310	Scophthalmus_maximus
ENSMUSG00000030400	Ercc2	97	84.488	ENSSDUG00000002397	ercc2	99	84.488	Seriola_dumerili
ENSMUSG00000030400	Ercc2	97	84.639	ENSSLDG00000020353	ercc2	99	84.639	Seriola_lalandi_dorsalis
ENSMUSG00000030400	Ercc2	99	85.420	ENSSPAG00000002074	ercc2	99	85.420	Stegastes_partitus
ENSMUSG00000030400	Ercc2	99	84.536	ENSTRUG00000007303	ercc2	99	84.536	Takifugu_rubripes
ENSMUSG00000030400	Ercc2	99	98.088	ENSUAMG00000019562	ERCC2	99	98.088	Ursus_americanus
ENSMUSG00000030400	Ercc2	99	81.176	ENSXMAG00000003922	ercc2	99	81.176	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000019	regulation of mitotic recombination	21873635.	IBA	Process
GO:0000166	nucleotide binding	-	IEA	Function
GO:0000439	transcription factor TFIIH core complex	-	ISO	Component
GO:0000717	nucleotide-excision repair, DNA duplex unwinding	21873635.	IBA	Process
GO:0001701	in utero embryonic development	17020410.	IMP	Process
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003684	damaged DNA binding	21873635.	IBA	Function
GO:0004003	ATP-dependent DNA helicase activity	21873635.	IBA	Function
GO:0004386	helicase activity	-	IEA	Function
GO:0004672	protein kinase activity	-	ISO	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	17952069.	IDA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005669	transcription factor TFIID complex	-	ISO	Component
GO:0005675	transcription factor TFIIH holo complex	-	ISO	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005819	spindle	-	ISO	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005856	cytoskeleton	-	IEA	Component
GO:0006139	nucleobase-containing compound metabolic process	-	IEA	Process
GO:0006281	DNA repair	11950998.	IMP	Process
GO:0006283	transcription-coupled nucleotide-excision repair	-	ISO	Process
GO:0006289	nucleotide-excision repair	9651581.11950998.	IMP	Process
GO:0006289	nucleotide-excision repair	-	ISO	Process
GO:0006366	transcription by RNA polymerase II	21873635.	IBA	Process
GO:0006366	transcription by RNA polymerase II	-	ISO	Process
GO:0006915	apoptotic process	-	ISO	Process
GO:0006974	cellular response to DNA damage stimulus	-	IEA	Process
GO:0006979	response to oxidative stress	21873635.	IBA	Process
GO:0006979	response to oxidative stress	11950998.	IMP	Process
GO:0006979	response to oxidative stress	-	ISO	Process
GO:0007059	chromosome segregation	-	ISO	Process
GO:0007568	aging	11950998.17020410.18545656.	IMP	Process
GO:0008022	protein C-terminus binding	-	ISO	Function
GO:0008026	ATP-dependent helicase activity	-	IEA	Function
GO:0008094	DNA-dependent ATPase activity	-	ISO	Function
GO:0008283	cell proliferation	17554309.	IMP	Process
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	21873635.	IBA	Function
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	-	ISO	Function
GO:0009411	response to UV	21873635.	IBA	Process
GO:0009411	response to UV	17020410.	IMP	Process
GO:0009650	UV protection	9651581.	IMP	Process
GO:0009650	UV protection	-	ISO	Process
GO:0009791	post-embryonic development	11950998.17020410.	IMP	Process
GO:0016787	hydrolase activity	-	IEA	Function
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	-	IEA	Function
GO:0021510	spinal cord development	17020410.	IMP	Process
GO:0022405	hair cycle process	17020410.	IMP	Process
GO:0030198	extracellular matrix organization	9651581.	IMP	Process
GO:0030282	bone mineralization	17020410.	IMP	Process
GO:0030674	protein binding, bridging	-	ISO	Function
GO:0032289	central nervous system myelin formation	17952069.	IMP	Process
GO:0033683	nucleotide-excision repair, DNA incision	21873635.	IBA	Process
GO:0033683	nucleotide-excision repair, DNA incision	-	ISO	Process
GO:0035264	multicellular organism growth	17020410.	IMP	Process
GO:0035315	hair cell differentiation	17020410.	IMP	Process
GO:0035315	hair cell differentiation	-	ISO	Process
GO:0040016	embryonic cleavage	9426063.	IMP	Process
GO:0043139	5'-3' DNA helicase activity	-	ISO	Function
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	21873635.	IBA	Function
GO:0043249	erythrocyte maturation	17020410.	IMP	Process
GO:0043388	positive regulation of DNA binding	17952069.	IMP	Process
GO:0043588	skin development	9651581.17020410.	IMP	Process
GO:0045893	positive regulation of transcription, DNA-templated	21873635.	IBA	Process
GO:0045893	positive regulation of transcription, DNA-templated	-	ISO	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	-	ISO	Process
GO:0045951	positive regulation of mitotic recombination	21873635.	IBA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0047485	protein N-terminus binding	-	ISO	Function
GO:0048820	hair follicle maturation	9651581.	IMP	Process
GO:0051536	iron-sulfur cluster binding	-	IEA	Function
GO:0051539	4 iron, 4 sulfur cluster binding	-	IEA	Function
GO:0060218	hematopoietic stem cell differentiation	17554309.	IMP	Process
GO:0070516	CAK-ERCC2 complex	-	ISO	Component
GO:0071817	MMXD complex	-	ISO	Component
GO:1901990	regulation of mitotic cell cycle phase transition	-	ISO	Process