EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000030536 (Gene tree)
Gene ID: 29875
Gene Symbol: Iqgap1
Alias: D7Ertd237e|D7Ertd257e
Full Name: IQ motif containing GTPase activating protein 1
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 114392
Position: chr7: 80711583-80825974
Accession: 1352757
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000205824	-	2307	-	-	- (aa)	-	-
ENSMUST00000205606	-	569	-	ENSMUSP00000145991	37 (aa)	-	A0A0U1RPI2
ENSMUST00000205383	-	2803	-	-	- (aa)	-	-
ENSMUST00000205540	-	3367	-	-	- (aa)	-	-
ENSMUST00000205304	-	484	-	ENSMUSP00000146126	101 (aa)	-	A0A0U1RPU3
ENSMUST00000167377	-	7444	XM_006540950	ENSMUSP00000128278	1657 (aa)	XP_006541013	Q9JKF1
ENSMUST00000206149	-	3629	-	-	- (aa)	-	-
ENSMUST00000205813	-	560	-	ENSMUSP00000145556	186 (aa)	-	A0A0U1RNG5

Gene Model

Click here to download ENSMUSG00000030536's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04520	Adherens junction	KEGG
mmu04810	Regulation of actin cytoskeleton	KEGG
mmu05205	Proteoglycans in cancer	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000030536's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000030536	Iqgap1	97	100.000	ENSG00000140575	IQGAP1	98	100.000	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001726	ruffle	-	ISO	Component
GO:0001817	regulation of cytokine production	21709260.	IMP	Process
GO:0005515	protein binding	16628219.18604197.20075861.	IPI	Function
GO:0005516	calmodulin binding	-	ISO	Function
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	-	ISO	Function
GO:0005634	nucleus	20883816.	IDA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005737	cytoplasm	14516655.18604197.	IDA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005874	microtubule	-	ISO	Component
GO:0005886	plasma membrane	-	ISO	Component
GO:0005911	cell-cell junction	18604197.	IDA	Component
GO:0005925	focal adhesion	-	ISO	Component
GO:0007165	signal transduction	-	IEA	Process
GO:0007173	epidermal growth factor receptor signaling pathway	17563371.	IMP	Process
GO:0007173	epidermal growth factor receptor signaling pathway	-	ISO	Process
GO:0007346	regulation of mitotic cell cycle	-	ISO	Process
GO:0008543	fibroblast growth factor receptor signaling pathway	17563371.	IMP	Process
GO:0015629	actin cytoskeleton	-	ISO	Component
GO:0015630	microtubule cytoskeleton	-	ISO	Component
GO:0016020	membrane	-	IEA	Component
GO:0016328	lateral plasma membrane	18604197.	IDA	Component
GO:0016477	cell migration	-	ISO	Process
GO:0017048	Rho GTPase binding	18604197.	IPI	Function
GO:0019901	protein kinase binding	-	ISO	Function
GO:0019903	protein phosphatase binding	-	ISO	Function
GO:0019904	protein domain specific binding	-	ISO	Function
GO:0030424	axon	-	ISO	Component
GO:0030426	growth cone	-	ISO	Component
GO:0030496	midbody	-	ISO	Component
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	-	ISO	Component
GO:0031252	cell leading edge	16369480.	IGI	Component
GO:0031267	small GTPase binding	-	ISO	Function
GO:0032991	protein-containing complex	-	ISO	Component
GO:0035305	negative regulation of dephosphorylation	21709260.	IGI	Process
GO:0036120	cellular response to platelet-derived growth factor stimulus	17563371.	IMP	Process
GO:0036464	cytoplasmic ribonucleoprotein granule	-	ISO	Component
GO:0043005	neuron projection	16369480.	IGI	Component
GO:0043005	neuron projection	-	ISO	Component
GO:0043087	regulation of GTPase activity	-	IEA	Process
GO:0043406	positive regulation of MAP kinase activity	-	ISO	Process
GO:0043539	protein serine/threonine kinase activator activity	-	ISO	Function
GO:0044344	cellular response to fibroblast growth factor stimulus	17563371.	IMP	Process
GO:0044548	S100 protein binding	-	ISO	Function
GO:0044877	protein-containing complex binding	-	ISO	Function
GO:0045121	membrane raft	-	ISO	Component
GO:0045860	positive regulation of protein kinase activity	17563371.	IMP	Process
GO:0045860	positive regulation of protein kinase activity	-	ISO	Process
GO:0048008	platelet-derived growth factor receptor signaling pathway	17563371.	IMP	Process
GO:0048365	Rac GTPase binding	18604197.	IPI	Function
GO:0051019	mitogen-activated protein kinase binding	-	ISO	Function
GO:0051894	positive regulation of focal adhesion assembly	-	ISO	Process
GO:0060090	molecular adaptor activity	-	ISO	Function
GO:0071277	cellular response to calcium ion	-	ISO	Process
GO:0071364	cellular response to epidermal growth factor stimulus	17563371.	IMP	Process
GO:0071364	cellular response to epidermal growth factor stimulus	-	ISO	Process
GO:1900006	positive regulation of dendrite development	-	ISO	Process
GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation	-	ISO	Process
GO:1903829	positive regulation of cellular protein localization	-	ISO	Process
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	-	ISO	Process
GO:1990138	neuron projection extension	-	ISO	Process
GO:1990904	ribonucleoprotein complex	21709260.	IDA	Component
GO:1990904	ribonucleoprotein complex	21709260.	IGI	Component