EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000030866 (Gene tree)
Gene ID: 26918
Gene Symbol: Ern2
Alias: Ire1b
Full Name: endoplasmic reticulum (ER) to nucleus signalling 2
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 16315 bases
Position: chr7:122169893-122186207
Accession: 1349436
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000033153	Ribonuc_2-5A	PF06479.12	3.7e-39	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000033153	-	2914	XM_011241817	ENSMUSP00000033153	911 (aa)	XP_011240119	Q9Z2E3
ENSMUST00000206198	-	2957	-	ENSMUSP00000145716	819 (aa)	-	Q3UTN5

Gene Model

Click here to download ENSMUSG00000030866's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000030866's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSMUSG00000030866	Ern2	95	47.290	ENSMUSG00000020715	Ern1	98	47.260

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000030866	Ern2	99	81.610	ENSG00000134398	ERN2	99	81.610	Homo_sapiens
ENSMUSG00000030866	Ern2	96	81.951	ENSAMEG00000014205	ERN2	98	80.984	Ailuropoda_melanoleuca
ENSMUSG00000030866	Ern2	95	54.849	ENSAPLG00000010981	ERN2	96	54.849	Anas_platyrhynchos
ENSMUSG00000030866	Ern2	99	56.620	ENSACAG00000012164	ERN2	99	56.620	Anolis_carolinensis
ENSMUSG00000030866	Ern2	99	81.264	ENSANAG00000016991	ERN2	99	81.264	Aotus_nancymaae
ENSMUSG00000030866	Ern2	97	80.000	ENSBTAG00000014456	ERN2	99	79.130	Bos_taurus
ENSMUSG00000030866	Ern2	99	80.283	ENSCJAG00000020632	ERN2	99	80.283	Callithrix_jacchus
ENSMUSG00000030866	Ern2	96	79.530	ENSCAFG00000017643	ERN2	98	79.103	Canis_familiaris
ENSMUSG00000030866	Ern2	97	76.201	ENSCAFG00020021342	ERN2	98	75.930	Canis_lupus_dingo
ENSMUSG00000030866	Ern2	96	82.022	ENSCHIG00000022191	ERN2	98	81.858	Capra_hircus
ENSMUSG00000030866	Ern2	98	81.788	ENSTSYG00000001334	ERN2	99	81.788	Carlito_syrichta
ENSMUSG00000030866	Ern2	80	81.308	ENSCAPG00000005936	ERN2	93	81.308	Cavia_aperea
ENSMUSG00000030866	Ern2	98	80.556	ENSCPOG00000005916	ERN2	99	80.556	Cavia_porcellus
ENSMUSG00000030866	Ern2	99	80.698	ENSCCAG00000035789	ERN2	99	80.807	Cebus_capucinus
ENSMUSG00000030866	Ern2	97	82.623	ENSCATG00000040324	ERN2	99	81.352	Cercocebus_atys
ENSMUSG00000030866	Ern2	95	81.193	ENSCLAG00000014120	ERN2	99	81.193	Chinchilla_lanigera
ENSMUSG00000030866	Ern2	97	81.717	ENSCSAG00000006703	ERN2	99	80.477	Chlorocebus_sabaeus
ENSMUSG00000030866	Ern2	95	56.781	ENSCPBG00000002165	ERN2	94	57.363	Chrysemys_picta_bellii
ENSMUSG00000030866	Ern2	99	81.393	ENSCANG00000015296	ERN2	99	81.393	Colobus_angolensis_palliatus
ENSMUSG00000030866	Ern2	96	89.852	ENSCGRG00001019098	Ern2	100	89.852	Cricetulus_griseus_chok1gshd
ENSMUSG00000030866	Ern2	96	76.239	ENSDNOG00000017619	ERN2	97	76.464	Dasypus_novemcinctus
ENSMUSG00000030866	Ern2	99	78.190	ENSDORG00000001246	Ern2	96	79.369	Dipodomys_ordii
ENSMUSG00000030866	Ern2	92	80.165	ENSETEG00000019530	ERN2	98	80.165	Echinops_telfairi
ENSMUSG00000030866	Ern2	98	80.288	ENSEASG00005017645	ERN2	98	80.288	Equus_asinus_asinus
ENSMUSG00000030866	Ern2	98	81.608	ENSECAG00000017742	ERN2	98	81.718	Equus_caballus
ENSMUSG00000030866	Ern2	87	76.667	ENSEEUG00000005382	ERN2	85	76.667	Erinaceus_europaeus
ENSMUSG00000030866	Ern2	96	81.594	ENSFCAG00000012945	ERN2	99	80.435	Felis_catus
ENSMUSG00000030866	Ern2	96	57.449	ENSFALG00000003790	ERN2	99	57.582	Ficedula_albicollis
ENSMUSG00000030866	Ern2	96	78.888	ENSFDAG00000006000	ERN2	98	78.822	Fukomys_damarensis
ENSMUSG00000030866	Ern2	95	56.703	ENSGAGG00000002490	ERN2	94	57.174	Gopherus_agassizii
ENSMUSG00000030866	Ern2	99	81.502	ENSGGOG00000012853	ERN2	99	81.502	Gorilla_gorilla
ENSMUSG00000030866	Ern2	96	81.962	ENSHGLG00000012125	ERN2	97	77.901	Heterocephalus_glaber_female
ENSMUSG00000030866	Ern2	97	81.278	ENSHGLG00100009410	ERN2	97	81.278	Heterocephalus_glaber_male
ENSMUSG00000030866	Ern2	97	83.221	ENSSTOG00000012411	ERN2	99	82.892	Ictidomys_tridecemlineatus
ENSMUSG00000030866	Ern2	96	82.786	ENSJJAG00000015169	Ern2	96	82.786	Jaculus_jaculus
ENSMUSG00000030866	Ern2	96	82.727	ENSLAFG00000005429	ERN2	98	82.294	Loxodonta_africana
ENSMUSG00000030866	Ern2	82	69.221	ENSMFAG00000038350	ERN2	90	69.221	Macaca_fascicularis
ENSMUSG00000030866	Ern2	97	82.399	ENSMMUG00000013806	ERN2	99	78.366	Macaca_mulatta
ENSMUSG00000030866	Ern2	97	82.511	ENSMNEG00000034382	ERN2	99	81.243	Macaca_nemestrina
ENSMUSG00000030866	Ern2	88	82.389	ENSMLEG00000040622	ERN2	99	82.389	Mandrillus_leucophaeus
ENSMUSG00000030866	Ern2	95	59.218	ENSMGAG00000006523	ERN2	96	59.598	Meleagris_gallopavo
ENSMUSG00000030866	Ern2	100	82.314	ENSMAUG00000013187	Ern2	99	82.642	Mesocricetus_auratus
ENSMUSG00000030866	Ern2	96	81.440	ENSMICG00000007841	ERN2	98	81.264	Microcebus_murinus
ENSMUSG00000030866	Ern2	99	88.767	ENSMOCG00000000736	Ern2	98	88.767	Microtus_ochrogaster
ENSMUSG00000030866	Ern2	95	65.784	ENSMODG00000006717	ERN2	97	64.952	Monodelphis_domestica
ENSMUSG00000030866	Ern2	100	98.353	MGP_CAROLIEiJ_G0030420	Ern2	100	98.411	Mus_caroli
ENSMUSG00000030866	Ern2	100	97.695	MGP_PahariEiJ_G0013630	Ern2	100	97.957	Mus_pahari
ENSMUSG00000030866	Ern2	100	98.573	MGP_SPRETEiJ_G0031534	Ern2	100	98.573	Mus_spretus
ENSMUSG00000030866	Ern2	96	80.808	ENSMPUG00000012189	ERN2	98	80.330	Mustela_putorius_furo
ENSMUSG00000030866	Ern2	89	72.571	ENSMLUG00000012167	ERN2	99	72.571	Myotis_lucifugus
ENSMUSG00000030866	Ern2	97	85.989	ENSNGAG00000021537	Ern2	97	85.989	Nannospalax_galili
ENSMUSG00000030866	Ern2	92	82.884	ENSNLEG00000011950	ERN2	93	82.884	Nomascus_leucogenys
ENSMUSG00000030866	Ern2	95	63.605	ENSOANG00000007667	-	99	63.720	Ornithorhynchus_anatinus
ENSMUSG00000030866	Ern2	98	76.752	ENSOCUG00000008483	ERN2	99	77.282	Oryctolagus_cuniculus
ENSMUSG00000030866	Ern2	98	81.556	ENSOGAG00000005577	ERN2	98	81.556	Otolemur_garnettii
ENSMUSG00000030866	Ern2	96	80.474	ENSOARG00000017432	ERN2	99	80.587	Ovis_aries
ENSMUSG00000030866	Ern2	99	81.719	ENSPPAG00000037128	ERN2	99	81.719	Pan_paniscus
ENSMUSG00000030866	Ern2	96	81.818	ENSPPRG00000001852	ERN2	99	80.652	Panthera_pardus
ENSMUSG00000030866	Ern2	96	78.812	ENSPTIG00000016188	ERN2	99	77.850	Panthera_tigris_altaica
ENSMUSG00000030866	Ern2	99	81.393	ENSPTRG00000007893	ERN2	99	81.393	Pan_troglodytes
ENSMUSG00000030866	Ern2	99	81.570	ENSPANG00000023632	ERN2	99	81.570	Papio_anubis
ENSMUSG00000030866	Ern2	100	88.840	ENSPEMG00000012773	Ern2	100	88.840	Peromyscus_maniculatus_bairdii
ENSMUSG00000030866	Ern2	95	64.939	ENSPCIG00000026605	ERN2	97	64.757	Phascolarctos_cinereus
ENSMUSG00000030866	Ern2	97	82.662	ENSPPYG00000007196	ERN2	94	81.393	Pongo_abelii
ENSMUSG00000030866	Ern2	98	78.761	ENSPCAG00000016200	ERN2	93	78.761	Procavia_capensis
ENSMUSG00000030866	Ern2	96	80.248	ENSPCOG00000017614	ERN2	98	80.133	Propithecus_coquereli
ENSMUSG00000030866	Ern2	98	74.365	ENSPVAG00000008445	ERN2	93	74.365	Pteropus_vampyrus
ENSMUSG00000030866	Ern2	99	92.944	ENSRNOG00000018974	Ern2	98	92.944	Rattus_norvegicus
ENSMUSG00000030866	Ern2	97	82.755	ENSRBIG00000034872	ERN2	99	78.524	Rhinopithecus_bieti
ENSMUSG00000030866	Ern2	97	82.662	ENSRROG00000008752	ERN2	99	81.284	Rhinopithecus_roxellana
ENSMUSG00000030866	Ern2	85	72.247	ENSSBOG00000027251	ERN2	96	72.247	Saimiri_boliviensis_boliviensis
ENSMUSG00000030866	Ern2	95	66.027	ENSSHAG00000005538	ERN2	98	66.027	Sarcophilus_harrisii
ENSMUSG00000030866	Ern2	75	75.527	ENSSPUG00000010312	ERN2	76	75.527	Sphenodon_punctatus
ENSMUSG00000030866	Ern2	97	81.432	ENSSSCG00000040637	ERN2	93	80.631	Sus_scrofa
ENSMUSG00000030866	Ern2	96	82.034	ENSTBEG00000000414	ERN2	99	82.712	Tupaia_belangeri
ENSMUSG00000030866	Ern2	91	76.505	ENSTTRG00000005264	ERN2	94	76.623	Tursiops_truncatus
ENSMUSG00000030866	Ern2	96	77.803	ENSUAMG00000021038	ERN2	98	76.940	Ursus_americanus
ENSMUSG00000030866	Ern2	96	75.336	ENSUMAG00000008840	ERN2	98	74.917	Ursus_maritimus
ENSMUSG00000030866	Ern2	97	78.771	ENSVVUG00000005617	ERN2	99	77.850	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0000287	magnesium ion binding	-	ISO	Function
GO:0003824	catalytic activity	-	IEA	Function
GO:0004519	endonuclease activity	-	ISO	Function
GO:0004521	endoribonuclease activity	21873635.	IBA	Function
GO:0004540	ribonuclease activity	-	IEA	Function
GO:0004672	protein kinase activity	21873635.	IBA	Function
GO:0004674	protein serine/threonine kinase activity	21873635.	IBA	Function
GO:0004674	protein serine/threonine kinase activity	-	ISO	Function
GO:0005515	protein binding	10650002.	IPI	Function
GO:0005524	ATP binding	-	ISO	Function
GO:0005783	endoplasmic reticulum	-	IEA	Component
GO:0005789	endoplasmic reticulum membrane	21873635.	IBA	Component
GO:0006355	regulation of transcription, DNA-templated	9755171.	IDA	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0006468	protein phosphorylation	-	ISO	Process
GO:0006915	apoptotic process	-	IEA	Process
GO:0006986	response to unfolded protein	-	IEA	Process
GO:0007050	cell cycle arrest	9755171.	IDA	Process
GO:0007257	activation of JUN kinase activity	10650002.	IDA	Process
GO:0008152	metabolic process	-	IEA	Process
GO:0016020	membrane	-	IEA	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0016075	rRNA catabolic process	-	ISO	Process
GO:0016301	kinase activity	-	IEA	Function
GO:0016310	phosphorylation	-	IEA	Process
GO:0016740	transferase activity	-	IEA	Function
GO:0016787	hydrolase activity	-	IEA	Function
GO:0030263	apoptotic chromosome condensation	-	ISO	Process
GO:0030968	endoplasmic reticulum unfolded protein response	21873635.	IBA	Process
GO:0034976	response to endoplasmic reticulum stress	10650002.	IDA	Process
GO:0034976	response to endoplasmic reticulum stress	11238559.	IMP	Process
GO:0036498	IRE1-mediated unfolded protein response	21873635.	IBA	Process
GO:0045892	negative regulation of transcription, DNA-templated	-	ISO	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0051082	unfolded protein binding	21873635.	IBA	Function
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	21873635.	IBA	Process
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	9755171.	IDA	Process
GO:1990604	IRE1-TRAF2-ASK1 complex	21873635.	IBA	Component
GO:1990604	IRE1-TRAF2-ASK1 complex	12050113.	IDA	Component