EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000031328 (Gene tree)
Gene ID: 192176
Gene Symbol: Flna
Alias: ABP-280|Dilp2|F730004A14Rik|Fln1|GENA 379|actin-binding protein 280|filamin-1
Full Name: filamin%2C alpha
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 26360
Position: chrX: 74223461-74249820
Accession: 95556
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000101454	-	8345	-	ENSMUSP00000098997	2639 (aa)	-	B7FAU9
ENSMUST00000130007	-	7753	-	ENSMUSP00000121082	2583 (aa)	-	B7FAV1
ENSMUST00000133609	-	638	-	-	- (aa)	-	-
ENSMUST00000127463	-	841	-	ENSMUSP00000114827	280 (aa)	-	F6Z2C0
ENSMUST00000150554	-	832	-	ENSMUSP00000116758	277 (aa)	-	J3JS91
ENSMUST00000141528	-	1106	-	-	- (aa)	-	-
ENSMUST00000133174	-	632	-	-	- (aa)	-	-
ENSMUST00000124950	-	797	-	-	- (aa)	-	-
ENSMUST00000133288	-	558	-	-	- (aa)	-	-
ENSMUST00000033699	-	8312	XM_006527911	ENSMUSP00000033699	2647 (aa)	XP_006527974	Q8BTM8
ENSMUST00000130203	-	689	-	-	- (aa)	-	-
ENSMUST00000144429	-	8233	-	ENSMUSP00000123278	511 (aa)	-	F6XC15
ENSMUST00000127924	-	704	-	ENSMUSP00000117324	74 (aa)	-	F7AVL7
ENSMUST00000156766	-	738	-	-	- (aa)	-	-
ENSMUST00000114299	-	8456	XM_011247549	ENSMUSP00000109938	2639 (aa)	XP_011245851	B7FAU9

Gene Model

Click here to download ENSMUSG00000031328's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04010	MAPK signaling pathway	KEGG
mmu04510	Focal adhesion	KEGG
mmu05132	Salmonella infection	KEGG
mmu05205	Proteoglycans in cancer	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000031328's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000031328	Flna	100	98.917	ENSG00000196924	FLNA	99	100.000	Homo_sapiens
ENSMUSG00000031328	Flna	100	85.294	ENSMUSG00000068699	Flnc	89	85.294	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001525	angiogenesis	17172441.	IMP	Process
GO:0001664	G protein-coupled receptor binding	-	ISO	Function
GO:0001837	epithelial to mesenchymal transition	21709252.	IGI	Process
GO:0001974	blood vessel remodeling	17172441.	IMP	Process
GO:0003007	heart morphogenesis	17172441.	IMP	Process
GO:0003779	actin binding	9412467.	TAS	Function
GO:0005080	protein kinase C binding	12704190.	IDA	Function
GO:0005515	protein binding	8871564.9412467.11114196.12393796.15102471.18824598.23055941.24436304.	IPI	Function
GO:0005634	nucleus	-	ISO	Component
GO:0005730	nucleolus	-	ISO	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005802	trans-Golgi network	9412467.	IDA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005856	cytoskeleton	-	IEA	Component
GO:0005884	actin filament	-	ISO	Component
GO:0005884	actin filament	-	ISO	Component
GO:0005886	plasma membrane	-	ISO	Component
GO:0005903	brush border	22114352.	IDA	Component
GO:0005911	cell-cell junction	-	ISO	Component
GO:0005938	cell cortex	-	ISO	Component
GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	-	ISO	Process
GO:0008134	transcription factor binding	-	ISO	Function
GO:0010977	negative regulation of neuron projection development	25358863.	IGI	Process
GO:0015459	potassium channel regulator activity	24951510.	IMP	Function
GO:0015459	potassium channel regulator activity	-	ISO	Function
GO:0015629	actin cytoskeleton	-	ISO	Component
GO:0016479	negative regulation of transcription by RNA polymerase I	-	ISO	Process
GO:0017048	Rho GTPase binding	-	ISO	Function
GO:0017160	Ral GTPase binding	-	ISO	Function
GO:0019900	kinase binding	-	ISO	Function
GO:0021943	formation of radial glial scaffolds	-	ISO	Process
GO:0030018	Z disc	24951510.	IDA	Component
GO:0030030	cell projection organization	-	IEA	Process
GO:0030036	actin cytoskeleton organization	21709252.	IGI	Process
GO:0030334	regulation of cell migration	-	ISO	Process
GO:0030426	growth cone	25358863.	IDA	Component
GO:0030863	cortical cytoskeleton	-	ISO	Component
GO:0031267	small GTPase binding	-	ISO	Function
GO:0031523	Myb complex	18548008.	ISO	Component
GO:0031532	actin cytoskeleton reorganization	-	ISO	Process
GO:0031852	mu-type opioid receptor binding	-	ISO	Function
GO:0031941	filamentous actin	25358863.	IDA	Component
GO:0031941	filamentous actin	-	ISO	Component
GO:0032231	regulation of actin filament bundle assembly	20713593.	IMP	Process
GO:0032233	positive regulation of actin filament bundle assembly	-	ISO	Process
GO:0032432	actin filament bundle	24436304.	IDA	Component
GO:0034394	protein localization to cell surface	-	ISO	Process
GO:0034988	Fc-gamma receptor I complex binding	-	ISO	Function
GO:0042177	negative regulation of protein catabolic process	-	ISO	Process
GO:0042307	positive regulation of protein import into nucleus	-	ISO	Process
GO:0042789	mRNA transcription by RNA polymerase II	-	ISO	Process
GO:0042803	protein homodimerization activity	-	ISO	Function
GO:0043025	neuronal cell body	-	ISO	Component
GO:0043066	negative regulation of apoptotic process	-	ISO	Process
GO:0043113	receptor clustering	-	ISO	Process
GO:0043198	dendritic shaft	-	ISO	Component
GO:0043433	negative regulation of DNA-binding transcription factor activity	-	ISO	Process
GO:0044319	wound healing, spreading of cells	-	ISO	Process
GO:0044325	ion channel binding	-	ISO	Function
GO:0044877	protein-containing complex binding	-	ISO	Function
GO:0045022	early endosome to late endosome transport	9412467.	IDA	Process
GO:0045184	establishment of protein localization	-	ISO	Process
GO:0045216	cell-cell junction organization	17172441.	IMP	Process
GO:0046332	SMAD binding	-	ISO	Function
GO:0048365	Rac GTPase binding	-	ISO	Function
GO:0048471	perinuclear region of cytoplasm	-	ISO	Component
GO:0050808	synapse organization	26972007.	IDA	Process
GO:0050808	synapse organization	26972007.	IMP	Process
GO:0050821	protein stabilization	-	ISO	Process
GO:0051015	actin filament binding	-	ISO	Function
GO:0051020	GTPase binding	-	ISO	Function
GO:0051220	cytoplasmic sequestering of protein	-	ISO	Process
GO:0051764	actin crosslink formation	-	ISO	Process
GO:0060271	cilium assembly	-	ISO	Process
GO:0071526	semaphorin-plexin signaling pathway	25358863.	IEP	Process
GO:0071526	semaphorin-plexin signaling pathway	25358863.	IGI	Process
GO:0071526	semaphorin-plexin signaling pathway	-	ISO	Process
GO:0072659	protein localization to plasma membrane	24951510.	IMP	Process
GO:0072659	protein localization to plasma membrane	-	ISO	Process
GO:0090307	mitotic spindle assembly	18548008.	ISO	Process
GO:0097368	establishment of Sertoli cell barrier	-	ISO	Process
GO:0097440	apical dendrite	-	ISO	Component
GO:0098794	postsynapse	-	ISO	Component
GO:0098978	glutamatergic synapse	-	ISO	Component
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	-	ISO	Process
GO:1901381	positive regulation of potassium ion transmembrane transport	24951510.	IMP	Process
GO:1901381	positive regulation of potassium ion transmembrane transport	-	ISO	Process
GO:1902396	protein localization to bicellular tight junction	-	ISO	Process
GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential	24951510.	IC	Process
GO:1905031	regulation of membrane repolarization during cardiac muscle cell action potential	24951510.	IMP	Process
GO:2000179	positive regulation of neural precursor cell proliferation	-	ISO	Process
GO:2001046	positive regulation of integrin-mediated signaling pathway	-	ISO	Process
GO:2001224	positive regulation of neuron migration	-	ISO	Process