EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000034120 (Gene tree)
Gene ID: 20382
Gene Symbol: Srsf2
Alias: D11Wsu175e|MRF-1|SC35|Sfrs10|Sfrs2
Full Name: serine/arginine-rich splicing factor 2
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Minus strand
Length: 3194 bases
Position: chr11:116849901-116853094
Accession: 98284
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000090059	RRM_1	PF00076.22	1.2e-21	1	1
ENSMUSP00000140016	RRM_1	PF00076.22	1.2e-21	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
25993413	Label-Free Protein RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression	IC & MEF	2015	Boucas J	DOI: 10.1371/journal.pone.0125745
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000092404	-	1899	XM_011248835	ENSMUSP00000090059	221 (aa)	XP_011247137	Q62093
ENSMUST00000138484	-	1814	-	-	- (aa)	-	-
ENSMUST00000136914	-	1336	-	ENSMUSP00000120086	221 (aa)	-	Q62093
ENSMUST00000176834	-	620	-	ENSMUSP00000134907	19 (aa)	-	H3BJA4
ENSMUST00000177429	-	433	-	-	- (aa)	-	-
ENSMUST00000190993	-	1326	-	ENSMUSP00000140016	221 (aa)	-	Q62093

Gene Model

Click here to download ENSMUSG00000034120's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03040	Spliceosome	KEGG
mmu05168	Herpes simplex virus 1 infection	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000034120's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSMUSG00000034120	Srsf2	53	37.692	ENSMUSG00000024097	Srsf7	64	39.130

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000034120	Srsf2	100	100.000	ENSG00000161547	SRSF2	100	100.000	Homo_sapiens
ENSMUSG00000034120	Srsf2	100	99.095	ENSACAG00000008553	-	100	99.095	Anolis_carolinensis
ENSMUSG00000034120	Srsf2	100	100.000	ENSANAG00000004226	SRSF2	100	100.000	Aotus_nancymaae
ENSMUSG00000034120	Srsf2	100	100.000	ENSBTAG00000018258	SRSF2	100	100.000	Bos_taurus
ENSMUSG00000034120	Srsf2	100	100.000	ENSCJAG00000041154	SRSF2	100	100.000	Callithrix_jacchus
ENSMUSG00000034120	Srsf2	100	99.548	ENSCAFG00000005147	SRSF2	100	99.548	Canis_familiaris
ENSMUSG00000034120	Srsf2	100	100.000	ENSCAFG00020006267	-	100	100.000	Canis_lupus_dingo
ENSMUSG00000034120	Srsf2	100	100.000	ENSCHIG00000017001	-	100	100.000	Capra_hircus
ENSMUSG00000034120	Srsf2	50	100.000	ENSTSYG00000006517	-	50	100.000	Carlito_syrichta
ENSMUSG00000034120	Srsf2	100	99.095	ENSCCAG00000037532	SRSF2	100	99.095	Cebus_capucinus
ENSMUSG00000034120	Srsf2	100	100.000	ENSCATG00000033650	SRSF2	100	100.000	Cercocebus_atys
ENSMUSG00000034120	Srsf2	100	100.000	ENSCSAG00000005108	SRSF2	100	100.000	Chlorocebus_sabaeus
ENSMUSG00000034120	Srsf2	100	100.000	ENSCPBG00000027975	-	100	100.000	Chrysemys_picta_bellii
ENSMUSG00000034120	Srsf2	100	100.000	ENSCANG00000028176	SRSF2	100	100.000	Colobus_angolensis_palliatus
ENSMUSG00000034120	Srsf2	100	100.000	ENSCGRG00001023483	Srsf2	100	100.000	Cricetulus_griseus_chok1gshd
ENSMUSG00000034120	Srsf2	54	94.167	ENSDARG00000057484	srsf2a	85	96.000	Danio_rerio
ENSMUSG00000034120	Srsf2	100	100.000	ENSDNOG00000000439	-	100	100.000	Dasypus_novemcinctus
ENSMUSG00000034120	Srsf2	100	100.000	ENSEASG00005004319	-	100	100.000	Equus_asinus_asinus
ENSMUSG00000034120	Srsf2	100	100.000	ENSECAG00000033515	-	100	100.000	Equus_caballus
ENSMUSG00000034120	Srsf2	100	100.000	ENSFCAG00000043466	-	100	100.000	Felis_catus
ENSMUSG00000034120	Srsf2	100	98.190	ENSGALG00000017357	SRSF2	100	98.190	Gallus_gallus
ENSMUSG00000034120	Srsf2	100	100.000	ENSGAGG00000024457	-	100	100.000	Gopherus_agassizii
ENSMUSG00000034120	Srsf2	100	92.760	ENSGGOG00000014378	SRSF2	100	92.760	Gorilla_gorilla
ENSMUSG00000034120	Srsf2	100	100.000	ENSHGLG00000017262	-	100	100.000	Heterocephalus_glaber_female
ENSMUSG00000034120	Srsf2	100	100.000	ENSJJAG00000013794	Srsf2	100	100.000	Jaculus_jaculus
ENSMUSG00000034120	Srsf2	51	95.536	ENSLACG00000013394	srsf2a	51	95.536	Latimeria_chalumnae
ENSMUSG00000034120	Srsf2	100	100.000	ENSMFAG00000045524	SRSF2	100	100.000	Macaca_fascicularis
ENSMUSG00000034120	Srsf2	100	94.570	ENSMMUG00000022413	SRSF2	100	94.570	Macaca_mulatta
ENSMUSG00000034120	Srsf2	100	100.000	ENSMNEG00000031444	SRSF2	100	100.000	Macaca_nemestrina
ENSMUSG00000034120	Srsf2	100	85.068	ENSMLEG00000025525	SRSF2	100	85.068	Mandrillus_leucophaeus
ENSMUSG00000034120	Srsf2	100	100.000	ENSMAUG00000022242	Srsf2	100	100.000	Mesocricetus_auratus
ENSMUSG00000034120	Srsf2	100	100.000	ENSMICG00000016956	-	100	100.000	Microcebus_murinus
ENSMUSG00000034120	Srsf2	99	98.630	ENSMODG00000001575	-	86	98.630	Monodelphis_domestica
ENSMUSG00000034120	Srsf2	100	100.000	MGP_CAROLIEiJ_G0017457	Srsf2	100	100.000	Mus_caroli
ENSMUSG00000034120	Srsf2	100	100.000	MGP_PahariEiJ_G0018587	Srsf2	100	100.000	Mus_pahari
ENSMUSG00000034120	Srsf2	100	100.000	MGP_SPRETEiJ_G0018303	Srsf2	100	100.000	Mus_spretus
ENSMUSG00000034120	Srsf2	100	100.000	ENSNGAG00000021718	Srsf2	100	100.000	Nannospalax_galili
ENSMUSG00000034120	Srsf2	50	100.000	ENSNLEG00000002547	SRSF2	51	100.000	Nomascus_leucogenys
ENSMUSG00000034120	Srsf2	100	100.000	ENSMEUG00000016745	-	100	100.000	Notamacropus_eugenii
ENSMUSG00000034120	Srsf2	100	100.000	ENSODEG00000014748	-	100	100.000	Octodon_degus
ENSMUSG00000034120	Srsf2	54	100.000	ENSOANG00000002695	-	100	100.000	Ornithorhynchus_anatinus
ENSMUSG00000034120	Srsf2	100	100.000	ENSOGAG00000028335	-	100	100.000	Otolemur_garnettii
ENSMUSG00000034120	Srsf2	99	49.545	ENSOARG00000018359	-	50	73.000	Ovis_aries
ENSMUSG00000034120	Srsf2	99	49.545	ENSOARG00000018667	-	50	73.000	Ovis_aries
ENSMUSG00000034120	Srsf2	100	100.000	ENSPPAG00000031433	SRSF2	100	100.000	Pan_paniscus
ENSMUSG00000034120	Srsf2	100	100.000	ENSPTRG00000009692	SRSF2	100	100.000	Pan_troglodytes
ENSMUSG00000034120	Srsf2	100	100.000	ENSPANG00000020023	SRSF2	100	100.000	Papio_anubis
ENSMUSG00000034120	Srsf2	100	100.000	ENSPCIG00000005334	-	100	100.000	Phascolarctos_cinereus
ENSMUSG00000034120	Srsf2	100	100.000	ENSPPYG00000008668	SRSF2	100	100.000	Pongo_abelii
ENSMUSG00000034120	Srsf2	100	100.000	ENSPCOG00000023806	-	100	100.000	Propithecus_coquereli
ENSMUSG00000034120	Srsf2	54	100.000	ENSPVAG00000014264	-	100	100.000	Pteropus_vampyrus
ENSMUSG00000034120	Srsf2	100	100.000	ENSRNOG00000000248	Srsf2	100	100.000	Rattus_norvegicus
ENSMUSG00000034120	Srsf2	100	100.000	ENSRBIG00000034493	SRSF2	100	100.000	Rhinopithecus_bieti
ENSMUSG00000034120	Srsf2	100	100.000	ENSRROG00000042457	SRSF2	100	100.000	Rhinopithecus_roxellana
ENSMUSG00000034120	Srsf2	100	88.688	ENSSBOG00000030904	SRSF2	100	88.688	Saimiri_boliviensis_boliviensis
ENSMUSG00000034120	Srsf2	100	99.550	ENSSHAG00000005932	-	100	99.550	Sarcophilus_harrisii
ENSMUSG00000034120	Srsf2	100	93.665	ENSSPUG00000007582	-	100	93.665	Sphenodon_punctatus
ENSMUSG00000034120	Srsf2	64	67.832	ENSSSCG00000012212	-	51	77.000	Sus_scrofa
ENSMUSG00000034120	Srsf2	100	99.548	ENSSSCG00000036592	-	100	99.548	Sus_scrofa
ENSMUSG00000034120	Srsf2	100	97.738	ENSTGUG00000007799	-	100	97.738	Taeniopygia_guttata
ENSMUSG00000034120	Srsf2	100	100.000	ENSTBEG00000014339	-	100	100.000	Tupaia_belangeri
ENSMUSG00000034120	Srsf2	100	100.000	ENSUAMG00000013403	-	100	100.000	Ursus_americanus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	21470964.	IDA	Process
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0005080	protein kinase C binding	-	ISO	Function
GO:0005515	protein binding	11739632.18641664.21470964.22570411.23663783.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	11641275.11739632.26013685.	IDA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005681	spliceosomal complex	11827461.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0016607	nuclear speck	21873635.	IBA	Component
GO:0016607	nuclear speck	15564382.16376875.20356838.22840402.23512658.25896510.26013685.	IDA	Component
GO:0016607	nuclear speck	15798186.21984414.23562910.	ISO	Component
GO:0035061	interchromatin granule	-	ISO	Component
GO:0036002	pre-mRNA binding	21470964.	IDA	Function
GO:0043484	regulation of RNA splicing	-	IEA	Process
GO:0045292	mRNA cis splicing, via spliceosome	21873635.	IBA	Process