EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000037851 (Gene tree)
Gene ID: 105148
Gene Symbol: Iars
Alias: 2510016L12Rik|E430001P04Rik
Full Name: isoleucine-tRNA synthetase
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 52168 bases
Position: chr13:49682100-49734267
Accession: 2145219
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000048096	tRNA-synt_1g	PF09334.11	8.3e-15	1	1
ENSMUSP00000126806	tRNA-synt_1g	PF09334.11	8.3e-15	1	1
ENSMUSP00000132082	tRNA-synt_1g	PF09334.11	8.3e-15	1	1
ENSMUSP00000048096	Anticodon_1	PF08264.13	6.3e-22	1	1
ENSMUSP00000126806	Anticodon_1	PF08264.13	6.3e-22	1	1
ENSMUSP00000132082	Anticodon_1	PF08264.13	6.3e-22	1	1
ENSMUSP00000048096	tRNA-synt_1	PF00133.22	3.5e-244	1	1
ENSMUSP00000126806	tRNA-synt_1	PF00133.22	3.5e-244	1	1
ENSMUSP00000132082	tRNA-synt_1	PF00133.22	3.5e-244	1	1
ENSMUSP00000130058	tRNA-synt_1	PF00133.22	1.3e-29	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000164275	-	889	-	-	- (aa)	-	-
ENSMUST00000172254	-	401	-	ENSMUSP00000130058	92 (aa)	-	E9Q866
ENSMUST00000171510	-	504	-	ENSMUSP00000130204	96 (aa)	-	F6Q6R1
ENSMUST00000165656	-	356	-	-	- (aa)	-	-
ENSMUST00000165063	-	787	-	-	- (aa)	-	-
ENSMUST00000165270	-	742	-	-	- (aa)	-	-
ENSMUST00000164260	-	3789	-	ENSMUSP00000126806	1262 (aa)	-	Q8BU30
ENSMUST00000165316	-	4426	XM_006516826	ENSMUSP00000132082	1262 (aa)	XP_006516889	Q8BU30
ENSMUST00000047363	-	4396	-	ENSMUSP00000048096	1262 (aa)	-	Q8BU30

Gene Model

Click here to download ENSMUSG00000037851's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu00970	Aminoacyl-tRNA biosynthesis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000037851's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSMUSG00000037851	Iars	65	45.000	ENSMUSG00000026618	Iars2	79	30.369
ENSMUSG00000037851	Iars	65	35.000	ENSMUSG00000035202	Lars2	71	30.337

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000037851	Iars	100	92.391	ENSG00000196305	IARS	100	92.121	Homo_sapiens
ENSMUSG00000037851	Iars	100	81.522	ENSAPOG00000002559	iars	100	74.310	Acanthochromis_polyacanthus
ENSMUSG00000037851	Iars	100	93.478	ENSAMEG00000013415	IARS	99	87.470	Ailuropoda_melanoleuca
ENSMUSG00000037851	Iars	100	84.783	ENSACIG00000018381	iars	100	72.498	Amphilophus_citrinellus
ENSMUSG00000037851	Iars	100	83.696	ENSAOCG00000006976	iars	99	77.426	Amphiprion_ocellaris
ENSMUSG00000037851	Iars	100	83.696	ENSAPEG00000005602	iars	100	75.789	Amphiprion_percula
ENSMUSG00000037851	Iars	100	83.696	ENSATEG00000024989	iars	100	75.710	Anabas_testudineus
ENSMUSG00000037851	Iars	100	91.304	ENSAPLG00000005750	IARS	99	81.329	Anas_platyrhynchos
ENSMUSG00000037851	Iars	100	90.217	ENSACAG00000009212	IARS	99	80.316	Anolis_carolinensis
ENSMUSG00000037851	Iars	100	94.565	ENSANAG00000035740	IARS	99	90.880	Aotus_nancymaae
ENSMUSG00000037851	Iars	100	82.609	ENSACLG00000017656	iars	100	74.843	Astatotilapia_calliptera
ENSMUSG00000037851	Iars	100	84.783	ENSAMXG00000036265	iars	100	75.296	Astyanax_mexicanus
ENSMUSG00000037851	Iars	100	95.652	ENSBTAG00000000974	IARS	99	89.532	Bos_taurus
ENSMUSG00000037851	Iars	96	64.773	WBGene00002152	iars-1	93	58.062	Caenorhabditis_elegans
ENSMUSG00000037851	Iars	100	94.565	ENSCJAG00000020465	IARS	99	90.176	Callithrix_jacchus
ENSMUSG00000037851	Iars	100	92.391	ENSCAFG00000002340	IARS	99	87.787	Canis_familiaris
ENSMUSG00000037851	Iars	100	92.391	ENSCAFG00020009677	IARS	99	89.312	Canis_lupus_dingo
ENSMUSG00000037851	Iars	100	94.565	ENSCHIG00000023719	IARS	99	89.929	Capra_hircus
ENSMUSG00000037851	Iars	100	92.391	ENSTSYG00000001294	IARS	100	89.461	Carlito_syrichta
ENSMUSG00000037851	Iars	95	85.405	ENSCAPG00000008012	IARS	92	85.405	Cavia_aperea
ENSMUSG00000037851	Iars	100	92.391	ENSCPOG00000000819	IARS	99	88.898	Cavia_porcellus
ENSMUSG00000037851	Iars	100	94.565	ENSCCAG00000022901	IARS	99	90.604	Cebus_capucinus
ENSMUSG00000037851	Iars	100	93.478	ENSCATG00000044530	IARS	99	86.980	Cercocebus_atys
ENSMUSG00000037851	Iars	88	100.000	ENSCLAG00000003319	IARS	97	100.000	Chinchilla_lanigera
ENSMUSG00000037851	Iars	100	93.478	ENSCSAG00000007241	IARS	99	90.801	Chlorocebus_sabaeus
ENSMUSG00000037851	Iars	88	90.789	ENSCHOG00000007264	IARS	87	90.789	Choloepus_hoffmanni
ENSMUSG00000037851	Iars	100	84.783	ENSCPBG00000001174	IARS	99	81.924	Chrysemys_picta_bellii
ENSMUSG00000037851	Iars	100	75.000	ENSCING00000002466	-	100	69.300	Ciona_intestinalis
ENSMUSG00000037851	Iars	100	78.261	ENSCSAVG00000008078	-	95	81.250	Ciona_savignyi
ENSMUSG00000037851	Iars	100	95.652	ENSCGRG00001023981	Iars	100	95.642	Cricetulus_griseus_chok1gshd
ENSMUSG00000037851	Iars	100	95.652	ENSCGRG00000007869	Iars	100	95.642	Cricetulus_griseus_crigri
ENSMUSG00000037851	Iars	100	81.522	ENSCSEG00000010191	iars	97	74.921	Cynoglossus_semilaevis
ENSMUSG00000037851	Iars	100	85.870	ENSCVAG00000023077	-	95	78.571	Cyprinodon_variegatus
ENSMUSG00000037851	Iars	100	83.696	ENSDARG00000007955	iars	100	74.450	Danio_rerio
ENSMUSG00000037851	Iars	100	94.565	ENSDNOG00000019773	IARS	99	86.967	Dasypus_novemcinctus
ENSMUSG00000037851	Iars	100	92.391	ENSDORG00000004383	Iars	100	90.333	Dipodomys_ordii
ENSMUSG00000037851	Iars	99	75.824	FBgn0027086	IleRS	96	55.659	Drosophila_melanogaster
ENSMUSG00000037851	Iars	100	94.565	ENSETEG00000004138	-	74	92.453	Echinops_telfairi
ENSMUSG00000037851	Iars	100	80.435	ENSEBUG00000016686	iars	100	61.605	Eptatretus_burgeri
ENSMUSG00000037851	Iars	100	93.478	ENSEASG00005009580	IARS	98	90.619	Equus_asinus_asinus
ENSMUSG00000037851	Iars	100	93.478	ENSECAG00000023253	IARS	93	90.818	Equus_caballus
ENSMUSG00000037851	Iars	100	93.478	ENSEEUG00000012427	IARS	85	93.502	Erinaceus_europaeus
ENSMUSG00000037851	Iars	100	83.696	ENSELUG00000015636	iars	100	71.057	Esox_lucius
ENSMUSG00000037851	Iars	100	93.478	ENSFCAG00000000817	IARS	99	88.818	Felis_catus
ENSMUSG00000037851	Iars	100	86.957	ENSFALG00000010261	IARS	93	80.455	Ficedula_albicollis
ENSMUSG00000037851	Iars	100	93.478	ENSFDAG00000010686	IARS	99	89.532	Fukomys_damarensis
ENSMUSG00000037851	Iars	100	85.870	ENSFHEG00000015399	iars	100	75.079	Fundulus_heteroclitus
ENSMUSG00000037851	Iars	100	80.435	ENSGMOG00000003632	iars	99	73.502	Gadus_morhua
ENSMUSG00000037851	Iars	100	91.304	ENSGALG00000004813	IARS	99	81.745	Gallus_gallus
ENSMUSG00000037851	Iars	100	85.870	ENSGAFG00000012832	iars	100	75.394	Gambusia_affinis
ENSMUSG00000037851	Iars	100	86.957	ENSGACG00000007055	iars	99	78.656	Gasterosteus_aculeatus
ENSMUSG00000037851	Iars	100	85.870	ENSGAGG00000017539	IARS	99	81.422	Gopherus_agassizii
ENSMUSG00000037851	Iars	100	92.391	ENSGGOG00000010212	IARS	99	90.642	Gorilla_gorilla
ENSMUSG00000037851	Iars	100	82.609	ENSHBUG00000010503	iars	97	75.710	Haplochromis_burtoni
ENSMUSG00000037851	Iars	100	95.652	ENSHGLG00000011793	IARS	99	89.929	Heterocephalus_glaber_female
ENSMUSG00000037851	Iars	100	89.130	ENSHGLG00100019375	-	99	89.532	Heterocephalus_glaber_male
ENSMUSG00000037851	Iars	72	85.507	ENSHGLG00100010624	-	97	75.375	Heterocephalus_glaber_male
ENSMUSG00000037851	Iars	100	81.522	ENSHCOG00000017482	iars	100	74.842	Hippocampus_comes
ENSMUSG00000037851	Iars	100	81.522	ENSIPUG00000012333	iars	100	74.980	Ictalurus_punctatus
ENSMUSG00000037851	Iars	100	95.652	ENSSTOG00000015173	IARS	99	92.942	Ictidomys_tridecemlineatus
ENSMUSG00000037851	Iars	100	93.478	ENSJJAG00000012564	Iars	100	92.314	Jaculus_jaculus
ENSMUSG00000037851	Iars	100	81.522	ENSKMAG00000011154	iars	99	74.901	Kryptolebias_marmoratus
ENSMUSG00000037851	Iars	100	83.696	ENSLBEG00000016283	iars	100	75.000	Labrus_bergylta
ENSMUSG00000037851	Iars	100	82.609	ENSLACG00000018913	IARS	100	78.831	Latimeria_chalumnae
ENSMUSG00000037851	Iars	100	83.696	ENSLOCG00000013871	iars	100	77.427	Lepisosteus_oculatus
ENSMUSG00000037851	Iars	100	93.478	ENSLAFG00000012996	IARS	99	88.025	Loxodonta_africana
ENSMUSG00000037851	Iars	100	93.478	ENSMFAG00000033748	IARS	99	87.071	Macaca_fascicularis
ENSMUSG00000037851	Iars	91	90.791	ENSMMUG00000004628	IARS	99	90.791	Macaca_mulatta
ENSMUSG00000037851	Iars	100	93.478	ENSMNEG00000018792	IARS	99	90.880	Macaca_nemestrina
ENSMUSG00000037851	Iars	100	93.478	ENSMLEG00000035022	IARS	99	86.915	Mandrillus_leucophaeus
ENSMUSG00000037851	Iars	100	83.696	ENSMAMG00000014297	iars	100	73.817	Mastacembelus_armatus
ENSMUSG00000037851	Iars	100	82.609	ENSMZEG00005013533	iars	100	74.843	Maylandia_zebra
ENSMUSG00000037851	Iars	100	91.304	ENSMGAG00000004555	IARS	99	81.804	Meleagris_gallopavo
ENSMUSG00000037851	Iars	100	95.404	ENSMAUG00000018695	Iars	100	95.404	Mesocricetus_auratus
ENSMUSG00000037851	Iars	100	95.652	ENSMICG00000014286	IARS	100	91.521	Microcebus_murinus
ENSMUSG00000037851	Iars	100	95.246	ENSMOCG00000022610	Iars	100	95.246	Microtus_ochrogaster
ENSMUSG00000037851	Iars	100	81.522	ENSMMOG00000010432	iars	94	74.012	Mola_mola
ENSMUSG00000037851	Iars	100	93.478	ENSMODG00000020876	IARS	99	82.871	Monodelphis_domestica
ENSMUSG00000037851	Iars	100	86.957	ENSMALG00000008778	iars	100	75.710	Monopterus_albus
ENSMUSG00000037851	Iars	100	100.000	MGP_CAROLIEiJ_G0018510	Iars	100	100.000	Mus_caroli
ENSMUSG00000037851	Iars	100	100.000	MGP_PahariEiJ_G0019576	Iars	100	100.000	Mus_pahari
ENSMUSG00000037851	Iars	100	100.000	MGP_SPRETEiJ_G0019390	Iars	100	100.000	Mus_spretus
ENSMUSG00000037851	Iars	100	91.304	ENSMPUG00000004835	IARS	99	84.909	Mustela_putorius_furo
ENSMUSG00000037851	Iars	100	94.565	ENSMLUG00000015180	IARS	99	88.739	Myotis_lucifugus
ENSMUSG00000037851	Iars	100	85.870	ENSNGAG00000001639	-	100	85.870	Nannospalax_galili
ENSMUSG00000037851	Iars	100	93.478	ENSNGAG00000007880	-	97	94.411	Nannospalax_galili
ENSMUSG00000037851	Iars	100	82.609	ENSNBRG00000022044	iars	100	75.552	Neolamprologus_brichardi
ENSMUSG00000037851	Iars	100	92.391	ENSNLEG00000016253	IARS	100	90.412	Nomascus_leucogenys
ENSMUSG00000037851	Iars	100	88.043	ENSMEUG00000011662	IARS	99	75.000	Notamacropus_eugenii
ENSMUSG00000037851	Iars	73	92.308	ENSOPRG00000009618	-	76	92.308	Ochotona_princeps
ENSMUSG00000037851	Iars	100	73.913	ENSODEG00000008400	-	98	70.399	Octodon_degus
ENSMUSG00000037851	Iars	100	94.565	ENSODEG00000004404	-	99	87.401	Octodon_degus
ENSMUSG00000037851	Iars	100	82.609	ENSONIG00000014366	iars	100	75.631	Oreochromis_niloticus
ENSMUSG00000037851	Iars	100	92.391	ENSOANG00000020510	-	79	92.424	Ornithorhynchus_anatinus
ENSMUSG00000037851	Iars	86	81.919	ENSOANG00000000112	-	100	81.919	Ornithorhynchus_anatinus
ENSMUSG00000037851	Iars	100	94.565	ENSOCUG00000016888	IARS	99	90.642	Oryctolagus_cuniculus
ENSMUSG00000037851	Iars	100	84.783	ENSORLG00000004747	iars	100	75.000	Oryzias_latipes
ENSMUSG00000037851	Iars	100	83.696	ENSORLG00020018714	iars	100	68.843	Oryzias_latipes_hni
ENSMUSG00000037851	Iars	100	84.783	ENSORLG00015014606	iars	100	74.921	Oryzias_latipes_hsok
ENSMUSG00000037851	Iars	100	84.783	ENSOMEG00000020072	iars	100	75.237	Oryzias_melastigma
ENSMUSG00000037851	Iars	100	94.565	ENSOGAG00000015426	IARS	100	90.103	Otolemur_garnettii
ENSMUSG00000037851	Iars	100	94.565	ENSOARG00000008328	IARS	99	89.620	Ovis_aries
ENSMUSG00000037851	Iars	100	92.391	ENSPPAG00000027754	IARS	99	90.960	Pan_paniscus
ENSMUSG00000037851	Iars	100	93.478	ENSPPRG00000008953	IARS	99	88.660	Panthera_pardus
ENSMUSG00000037851	Iars	91	88.184	ENSPTIG00000015464	IARS	99	88.184	Panthera_tigris_altaica
ENSMUSG00000037851	Iars	100	92.391	ENSPTRG00000021108	IARS	100	90.933	Pan_troglodytes
ENSMUSG00000037851	Iars	100	93.478	ENSPANG00000024723	IARS	99	87.071	Papio_anubis
ENSMUSG00000037851	Iars	100	88.043	ENSPKIG00000025011	iars	100	75.513	Paramormyrops_kingsleyae
ENSMUSG00000037851	Iars	100	83.696	ENSPSIG00000011011	IARS	99	80.553	Pelodiscus_sinensis
ENSMUSG00000037851	Iars	100	81.522	ENSPMGG00000005379	iars	100	71.689	Periophthalmus_magnuspinnatus
ENSMUSG00000037851	Iars	100	96.739	ENSPEMG00000012867	Iars	100	95.880	Peromyscus_maniculatus_bairdii
ENSMUSG00000037851	Iars	100	79.348	ENSPMAG00000000527	-	100	80.402	Petromyzon_marinus
ENSMUSG00000037851	Iars	100	93.478	ENSPCIG00000023807	IARS	92	82.292	Phascolarctos_cinereus
ENSMUSG00000037851	Iars	100	84.783	ENSPFOG00000011883	iars	100	74.369	Poecilia_formosa
ENSMUSG00000037851	Iars	100	84.783	ENSPLAG00000012010	iars	100	74.369	Poecilia_latipinna
ENSMUSG00000037851	Iars	100	84.783	ENSPMEG00000018215	iars	100	74.369	Poecilia_mexicana
ENSMUSG00000037851	Iars	100	83.696	ENSPREG00000006938	iars	100	74.606	Poecilia_reticulata
ENSMUSG00000037851	Iars	100	93.478	ENSPPYG00000019374	IARS	99	87.391	Pongo_abelii
ENSMUSG00000037851	Iars	100	90.217	ENSPCAG00000013215	IARS	99	81.840	Procavia_capensis
ENSMUSG00000037851	Iars	100	94.565	ENSPCOG00000017998	IARS	100	91.204	Propithecus_coquereli
ENSMUSG00000037851	Iars	100	94.565	ENSPVAG00000010269	IARS	93	89.256	Pteropus_vampyrus
ENSMUSG00000037851	Iars	100	82.609	ENSPNYG00000019391	iars	100	75.631	Pundamilia_nyererei
ENSMUSG00000037851	Iars	100	83.696	ENSPNAG00000008441	iars	98	73.491	Pygocentrus_nattereri
ENSMUSG00000037851	Iars	100	97.826	ENSRNOG00000052977	LOC103690033	100	98.204	Rattus_norvegicus
ENSMUSG00000037851	Iars	100	97.826	ENSRNOG00000014616	Iars	100	96.355	Rattus_norvegicus
ENSMUSG00000037851	Iars	100	93.478	ENSRBIG00000038873	IARS	99	89.392	Rhinopithecus_bieti
ENSMUSG00000037851	Iars	100	92.391	ENSRROG00000028942	IARS	99	90.801	Rhinopithecus_roxellana
ENSMUSG00000037851	Iars	92	61.176	YBL076C	ILS1	98	53.693	Saccharomyces_cerevisiae
ENSMUSG00000037851	Iars	100	94.565	ENSSBOG00000001596	IARS	99	90.397	Saimiri_boliviensis_boliviensis
ENSMUSG00000037851	Iars	97	81.796	ENSSHAG00000000237	IARS	99	81.878	Sarcophilus_harrisii
ENSMUSG00000037851	Iars	100	82.609	ENSSFOG00015001874	iars	100	73.402	Scleropages_formosus
ENSMUSG00000037851	Iars	100	85.870	ENSSMAG00000013630	iars	99	74.901	Scophthalmus_maximus
ENSMUSG00000037851	Iars	100	84.783	ENSSDUG00000016007	iars	100	75.710	Seriola_dumerili
ENSMUSG00000037851	Iars	100	84.783	ENSSLDG00000003987	iars	100	74.862	Seriola_lalandi_dorsalis
ENSMUSG00000037851	Iars	100	93.478	ENSSARG00000010543	IARS	99	87.242	Sorex_araneus
ENSMUSG00000037851	Iars	100	85.870	ENSSPUG00000002467	IARS	98	79.775	Sphenodon_punctatus
ENSMUSG00000037851	Iars	100	82.609	ENSSPAG00000020176	iars	100	75.079	Stegastes_partitus
ENSMUSG00000037851	Iars	100	94.565	ENSSSCG00000008068	IARS	99	91.667	Sus_scrofa
ENSMUSG00000037851	Iars	100	86.957	ENSTGUG00000004410	IARS	99	79.669	Taeniopygia_guttata
ENSMUSG00000037851	Iars	100	81.522	ENSTRUG00000007056	iars	100	74.901	Takifugu_rubripes
ENSMUSG00000037851	Iars	100	82.609	ENSTNIG00000014814	iars	99	74.901	Tetraodon_nigroviridis
ENSMUSG00000037851	Iars	100	94.565	ENSTBEG00000014010	IARS	75	94.697	Tupaia_belangeri
ENSMUSG00000037851	Iars	100	93.478	ENSTTRG00000008240	IARS	99	86.122	Tursiops_truncatus
ENSMUSG00000037851	Iars	100	94.565	ENSUAMG00000013778	IARS	99	87.946	Ursus_americanus
ENSMUSG00000037851	Iars	100	93.478	ENSUMAG00000015456	IARS	99	87.946	Ursus_maritimus
ENSMUSG00000037851	Iars	100	94.565	ENSVPAG00000008524	IARS	99	81.998	Vicugna_pacos
ENSMUSG00000037851	Iars	100	92.391	ENSVVUG00000004144	IARS	99	87.787	Vulpes_vulpes
ENSMUSG00000037851	Iars	100	84.783	ENSXETG00000020903	iars	99	73.978	Xenopus_tropicalis
ENSMUSG00000037851	Iars	100	84.783	ENSXMAG00000017562	iars	100	74.611	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000049	tRNA binding	-	IEA	Function
GO:0000166	nucleotide binding	-	IEA	Function
GO:0002161	aminoacyl-tRNA editing activity	-	IEA	Function
GO:0004812	aminoacyl-tRNA ligase activity	-	IEA	Function
GO:0004822	isoleucine-tRNA ligase activity	21873635.	IBA	Function
GO:0004822	isoleucine-tRNA ligase activity	12060739.	IMP	Function
GO:0004822	isoleucine-tRNA ligase activity	-	ISO	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005737	cytoplasm	-	ISO	Component
GO:0005829	cytosol	-	ISO	Component
GO:0006412	translation	-	IEA	Process
GO:0006418	tRNA aminoacylation for protein translation	-	IEA	Process
GO:0006428	isoleucyl-tRNA aminoacylation	21873635.	IBA	Process
GO:0006428	isoleucyl-tRNA aminoacylation	12060739.	IDA	Process
GO:0006428	isoleucyl-tRNA aminoacylation	-	ISO	Process
GO:0016874	ligase activity	-	IEA	Function
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	12060739.	IDA	Component
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	-	ISO	Component
GO:0051020	GTPase binding	-	ISO	Function