EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000037860 (Gene tree)
Gene ID: 383619
Gene Symbol: Aim2
Alias: Ifi210|LOC383619
Full Name: absent in melanoma 2
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 115162
Position: chr1: 173350879-173466040
Accession: 2686159
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000135370	-	372	-	-	- (aa)	-	-
ENSMUST00000166137	-	2079	XM_006496919	ENSMUSP00000132253	354 (aa)	XP_006496982	Q91VJ1
ENSMUST00000192575	-	363	-	-	- (aa)	-	-
ENSMUST00000151176	-	326	-	ENSMUSP00000121333	80 (aa)	-	D3Z341
ENSMUST00000173023	-	744	-	ENSMUSP00000134329	94 (aa)	-	G3UZ36
ENSMUST00000174263	-	383	-	-	- (aa)	-	-
ENSMUST00000147604	-	2839	XM_011238831	ENSMUSP00000119465	354 (aa)	XP_011237133	Q91VJ1

Gene Model

Click here to download ENSMUSG00000037860's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04621	NOD-like receptor signaling pathway	KEGG
mmu04623	Cytosolic DNA-sensing pathway	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000037860's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000037860	Aim2	100	42.029	ENSG00000163565	IFI16	85	41.546	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002218	activation of innate immune response	19158676.	IDA	Process
GO:0002218	activation of innate immune response	-	ISO	Process
GO:0002230	positive regulation of defense response to virus by host	19158675.	IMP	Process
GO:0002376	immune system process	-	IEA	Process
GO:0003677	DNA binding	-	IEA	Function
GO:0003690	double-stranded DNA binding	19158679.23567559.	IDA	Function
GO:0003690	double-stranded DNA binding	-	ISO	Function
GO:0005515	protein binding	19158679.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005737	cytoplasm	19158679.	IDA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005739	mitochondrion	-	ISO	Component
GO:0005829	cytosol	-	ISO	Component
GO:0006915	apoptotic process	-	IEA	Process
GO:0006954	inflammatory response	-	IEA	Process
GO:0032088	negative regulation of NF-kappaB transcription factor activity	-	ISO	Process
GO:0032461	positive regulation of protein oligomerization	-	ISO	Process
GO:0032731	positive regulation of interleukin-1 beta production	19158676.	IDA	Process
GO:0032731	positive regulation of interleukin-1 beta production	19158675.	IMP	Process
GO:0032731	positive regulation of interleukin-1 beta production	-	ISO	Process
GO:0033209	tumor necrosis factor-mediated signaling pathway	-	ISO	Process
GO:0035458	cellular response to interferon-beta	19158679.	IDA	Process
GO:0035690	cellular response to drug	19158679.	ISO	Process
GO:0042802	identical protein binding	19158676.	IPI	Function
GO:0042802	identical protein binding	-	ISO	Function
GO:0045087	innate immune response	-	IEA	Process
GO:0050702	interleukin-1 beta secretion	19158679.	ISO	Process
GO:0050718	positive regulation of interleukin-1 beta secretion	23997220.	IGI	Process
GO:0050718	positive regulation of interleukin-1 beta secretion	-	ISO	Process
GO:0051092	positive regulation of NF-kappaB transcription factor activity	-	ISO	Process
GO:0070269	pyroptosis	19158676.	IDA	Process
GO:0070269	pyroptosis	-	ISO	Process
GO:0097169	AIM2 inflammasome complex	19158679.	IDA	Component
GO:0097169	AIM2 inflammasome complex	-	ISO	Component
GO:2001056	positive regulation of cysteine-type endopeptidase activity	19158676.	IDA	Process
GO:2001056	positive regulation of cysteine-type endopeptidase activity	19131592.	IMP	Process
GO:2001056	positive regulation of cysteine-type endopeptidase activity	-	ISO	Process