EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000038290 (Gene tree)
Gene ID: 103677
Gene Symbol: Smg6
Alias: -
Full Name: Smg-6 homolog%2C nonsense mediated mRNA decay factor (C. elegans)
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Plus strand
Length: 238626 bases
Position: chr11:74925823-75164448
Accession: 2144117
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000043555	EST1	PF10374.9	1.1e-13	1	1
ENSMUSP00000043555	EST1_DNA_bind	PF10373.9	3.4e-60	1	1
ENSMUSP00000120060	EST1_DNA_bind	PF10373.9	1.7e-10	1	1
ENSMUSP00000043555	PIN_4	PF13638.6	3.3e-22	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000140197	-	714	-	ENSMUSP00000120060	238 (aa)	-	B1ARG9
ENSMUST00000135522	-	2200	-	-	- (aa)	-	-
ENSMUST00000142038	-	487	-	-	- (aa)	-	-
ENSMUST00000153226	-	637	-	-	- (aa)	-	-
ENSMUST00000130145	-	4078	-	ENSMUSP00000120229	356 (aa)	-	F6WT10
ENSMUST00000045281	-	5848	XM_011248659	ENSMUSP00000043555	1418 (aa)	XP_011246961	P61406

Gene Model

Click here to download ENSMUSG00000038290's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03015	mRNA surveillance pathway	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000038290's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000038290	Smg6	100	90.839	ENSG00000070366	SMG6	100	97.652	Homo_sapiens
ENSMUSG00000038290	Smg6	94	67.742	ENSAPOG00000019448	smg6	74	54.859	Acanthochromis_polyacanthus
ENSMUSG00000038290	Smg6	100	91.191	ENSAMEG00000007632	SMG6	100	91.191	Ailuropoda_melanoleuca
ENSMUSG00000038290	Smg6	96	65.915	ENSAOCG00000002630	smg6	74	54.411	Amphiprion_ocellaris
ENSMUSG00000038290	Smg6	96	65.915	ENSAPEG00000019101	smg6	74	54.489	Amphiprion_percula
ENSMUSG00000038290	Smg6	97	63.636	ENSATEG00000006483	smg6	73	54.560	Anabas_testudineus
ENSMUSG00000038290	Smg6	97	70.950	ENSACAG00000011783	SMG6	99	56.635	Anolis_carolinensis
ENSMUSG00000038290	Smg6	100	91.050	ENSANAG00000035760	SMG6	100	91.050	Aotus_nancymaae
ENSMUSG00000038290	Smg6	96	65.352	ENSACLG00000005288	smg6	80	54.710	Astatotilapia_calliptera
ENSMUSG00000038290	Smg6	96	66.282	ENSAMXG00000017326	smg6	99	50.554	Astyanax_mexicanus
ENSMUSG00000038290	Smg6	100	91.261	ENSBTAG00000000267	SMG6	100	91.261	Bos_taurus
ENSMUSG00000038290	Smg6	100	91.121	ENSCJAG00000001820	SMG6	100	91.121	Callithrix_jacchus
ENSMUSG00000038290	Smg6	100	90.909	ENSCAFG00000019260	SMG6	100	90.909	Canis_familiaris
ENSMUSG00000038290	Smg6	100	90.909	ENSCAFG00020009770	SMG6	100	90.909	Canis_lupus_dingo
ENSMUSG00000038290	Smg6	97	95.652	ENSCHIG00000021998	SMG6	100	91.261	Capra_hircus
ENSMUSG00000038290	Smg6	100	90.627	ENSTSYG00000003406	SMG6	100	97.652	Carlito_syrichta
ENSMUSG00000038290	Smg6	98	76.187	ENSCAPG00000016197	SMG6	99	83.138	Cavia_aperea
ENSMUSG00000038290	Smg6	99	93.249	ENSCPOG00000014878	SMG6	99	93.249	Cavia_porcellus
ENSMUSG00000038290	Smg6	100	91.332	ENSCCAG00000035801	SMG6	100	91.332	Cebus_capucinus
ENSMUSG00000038290	Smg6	100	91.261	ENSCATG00000031956	SMG6	100	91.261	Cercocebus_atys
ENSMUSG00000038290	Smg6	100	93.697	ENSCLAG00000006748	SMG6	100	93.697	Chinchilla_lanigera
ENSMUSG00000038290	Smg6	100	91.614	ENSCSAG00000013800	SMG6	100	91.614	Chlorocebus_sabaeus
ENSMUSG00000038290	Smg6	57	98.507	ENSCHOG00000005024	-	73	98.507	Choloepus_hoffmanni
ENSMUSG00000038290	Smg6	97	82.421	ENSCPBG00000020369	SMG6	100	71.975	Chrysemys_picta_bellii
ENSMUSG00000038290	Smg6	68	35.260	ENSCING00000010099	-	99	35.385	Ciona_intestinalis
ENSMUSG00000038290	Smg6	95	94.690	ENSCANG00000031764	SMG6	100	97.260	Colobus_angolensis_palliatus
ENSMUSG00000038290	Smg6	67	97.908	ENSCGRG00001019595	Smg6	98	93.470	Cricetulus_griseus_chok1gshd
ENSMUSG00000038290	Smg6	97	93.084	ENSCGRG00000007782	Smg6	100	88.753	Cricetulus_griseus_crigri
ENSMUSG00000038290	Smg6	96	63.483	ENSCSEG00000012757	smg6	90	52.065	Cynoglossus_semilaevis
ENSMUSG00000038290	Smg6	87	67.937	ENSCVAG00000012789	smg6	74	53.313	Cyprinodon_variegatus
ENSMUSG00000038290	Smg6	92	68.182	ENSDARG00000100481	smg6	90	56.115	Danio_rerio
ENSMUSG00000038290	Smg6	100	90.768	ENSDNOG00000048283	SMG6	100	90.768	Dasypus_novemcinctus
ENSMUSG00000038290	Smg6	95	95.575	ENSDORG00000016614	Smg6	94	97.297	Dipodomys_ordii
ENSMUSG00000038290	Smg6	93	100.000	ENSETEG00000016790	SMG6	93	100.000	Echinops_telfairi
ENSMUSG00000038290	Smg6	97	50.430	ENSEBUG00000005059	smg6	71	49.904	Eptatretus_burgeri
ENSMUSG00000038290	Smg6	99	91.390	ENSEASG00005009318	SMG6	99	91.390	Equus_asinus_asinus
ENSMUSG00000038290	Smg6	99	91.461	ENSECAG00000006519	SMG6	99	91.461	Equus_caballus
ENSMUSG00000038290	Smg6	100	80.550	ENSEEUG00000003493	SMG6	100	80.550	Erinaceus_europaeus
ENSMUSG00000038290	Smg6	91	68.997	ENSELUG00000005934	smg6	67	56.324	Esox_lucius
ENSMUSG00000038290	Smg6	100	91.684	ENSFCAG00000028817	SMG6	100	91.684	Felis_catus
ENSMUSG00000038290	Smg6	97	81.556	ENSFALG00000006538	SMG6	100	71.652	Ficedula_albicollis
ENSMUSG00000038290	Smg6	100	93.697	ENSFDAG00000015106	SMG6	100	93.697	Fukomys_damarensis
ENSMUSG00000038290	Smg6	87	68.889	ENSFHEG00000013282	smg6	74	53.349	Fundulus_heteroclitus
ENSMUSG00000038290	Smg6	83	56.459	ENSGMOG00000019077	smg6	58	68.224	Gadus_morhua
ENSMUSG00000038290	Smg6	97	80.692	ENSGALG00000003108	SMG6	98	71.478	Gallus_gallus
ENSMUSG00000038290	Smg6	87	68.889	ENSGAFG00000000379	smg6	74	53.485	Gambusia_affinis
ENSMUSG00000038290	Smg6	96	66.006	ENSGACG00000020521	smg6	100	52.790	Gasterosteus_aculeatus
ENSMUSG00000038290	Smg6	97	81.844	ENSGAGG00000025617	SMG6	100	71.784	Gopherus_agassizii
ENSMUSG00000038290	Smg6	100	91.402	ENSGGOG00000017156	SMG6	100	91.402	Gorilla_gorilla
ENSMUSG00000038290	Smg6	96	65.352	ENSHBUG00000021311	smg6	74	54.867	Haplochromis_burtoni
ENSMUSG00000038290	Smg6	100	93.277	ENSHGLG00000012882	SMG6	100	93.277	Heterocephalus_glaber_female
ENSMUSG00000038290	Smg6	100	93.277	ENSHGLG00100017815	SMG6	100	93.277	Heterocephalus_glaber_male
ENSMUSG00000038290	Smg6	97	61.648	ENSHCOG00000008761	smg6	96	53.607	Hippocampus_comes
ENSMUSG00000038290	Smg6	97	66.857	ENSIPUG00000012493	smg6	75	55.404	Ictalurus_punctatus
ENSMUSG00000038290	Smg6	100	94.958	ENSSTOG00000028127	SMG6	100	94.958	Ictidomys_tridecemlineatus
ENSMUSG00000038290	Smg6	97	96.542	ENSJJAG00000015367	Smg6	95	88.562	Jaculus_jaculus
ENSMUSG00000038290	Smg6	97	64.903	ENSKMAG00000000279	smg6	85	53.822	Kryptolebias_marmoratus
ENSMUSG00000038290	Smg6	96	65.915	ENSLBEG00000002184	smg6	73	53.643	Labrus_bergylta
ENSMUSG00000038290	Smg6	94	79.911	ENSLACG00000003276	SMG6	100	80.000	Latimeria_chalumnae
ENSMUSG00000038290	Smg6	77	83.273	ENSLACG00000000806	-	98	59.367	Latimeria_chalumnae
ENSMUSG00000038290	Smg6	95	95.133	ENSLAFG00000001261	SMG6	100	89.922	Loxodonta_africana
ENSMUSG00000038290	Smg6	100	91.473	ENSMFAG00000003394	SMG6	100	91.473	Macaca_fascicularis
ENSMUSG00000038290	Smg6	100	91.402	ENSMMUG00000023161	SMG6	100	91.402	Macaca_mulatta
ENSMUSG00000038290	Smg6	95	94.690	ENSMNEG00000044592	SMG6	100	86.920	Macaca_nemestrina
ENSMUSG00000038290	Smg6	93	97.368	ENSMLEG00000029353	SMG6	100	97.368	Mandrillus_leucophaeus
ENSMUSG00000038290	Smg6	96	66.197	ENSMAMG00000020119	smg6	79	55.504	Mastacembelus_armatus
ENSMUSG00000038290	Smg6	96	65.352	ENSMZEG00005024736	smg6	74	54.567	Maylandia_zebra
ENSMUSG00000038290	Smg6	52	90.244	ENSMGAG00000017200	-	100	85.286	Meleagris_gallopavo
ENSMUSG00000038290	Smg6	97	80.980	ENSMGAG00000005401	-	99	65.468	Meleagris_gallopavo
ENSMUSG00000038290	Smg6	96	96.943	ENSMAUG00000017203	-	99	96.943	Mesocricetus_auratus
ENSMUSG00000038290	Smg6	100	92.600	ENSMICG00000012913	SMG6	100	92.600	Microcebus_murinus
ENSMUSG00000038290	Smg6	99	95.763	ENSMOCG00000019924	-	99	95.763	Microtus_ochrogaster
ENSMUSG00000038290	Smg6	96	63.739	ENSMMOG00000010883	smg6	100	48.125	Mola_mola
ENSMUSG00000038290	Smg6	81	45.641	ENSMODG00000024395	-	99	40.509	Monodelphis_domestica
ENSMUSG00000038290	Smg6	73	48.295	ENSMODG00000024410	-	99	41.487	Monodelphis_domestica
ENSMUSG00000038290	Smg6	96	92.576	ENSMODG00000010622	SMG6	100	85.654	Monodelphis_domestica
ENSMUSG00000038290	Smg6	73	48.864	ENSMODG00000024463	-	99	42.074	Monodelphis_domestica
ENSMUSG00000038290	Smg6	73	48.864	ENSMODG00000024460	-	99	41.879	Monodelphis_domestica
ENSMUSG00000038290	Smg6	97	66.295	ENSMALG00000001106	smg6	73	55.210	Monopterus_albus
ENSMUSG00000038290	Smg6	100	98.739	MGP_CAROLIEiJ_G0016729	Smg6	100	98.739	Mus_caroli
ENSMUSG00000038290	Smg6	100	99.160	MGP_PahariEiJ_G0017866	Smg6	100	99.160	Mus_pahari
ENSMUSG00000038290	Smg6	100	99.718	MGP_SPRETEiJ_G0017572	Smg6	100	99.718	Mus_spretus
ENSMUSG00000038290	Smg6	97	94.524	ENSMPUG00000013046	SMG6	100	91.191	Mustela_putorius_furo
ENSMUSG00000038290	Smg6	100	90.557	ENSMLUG00000005739	SMG6	100	90.557	Myotis_lucifugus
ENSMUSG00000038290	Smg6	100	94.538	ENSNGAG00000007287	Smg6	100	94.538	Nannospalax_galili
ENSMUSG00000038290	Smg6	96	65.352	ENSNBRG00000009511	smg6	80	54.281	Neolamprologus_brichardi
ENSMUSG00000038290	Smg6	95	94.248	ENSNLEG00000017171	SMG6	100	97.456	Nomascus_leucogenys
ENSMUSG00000038290	Smg6	96	91.703	ENSMEUG00000015804	SMG6	100	82.112	Notamacropus_eugenii
ENSMUSG00000038290	Smg6	71	90.000	ENSOPRG00000000579	SMG6	83	98.421	Ochotona_princeps
ENSMUSG00000038290	Smg6	95	94.273	ENSODEG00000008038	SMG6	100	85.011	Octodon_degus
ENSMUSG00000038290	Smg6	96	65.642	ENSONIG00000005594	smg6	100	51.535	Oreochromis_niloticus
ENSMUSG00000038290	Smg6	97	87.032	ENSOANG00000021103	-	100	86.283	Ornithorhynchus_anatinus
ENSMUSG00000038290	Smg6	100	91.344	ENSOCUG00000013018	SMG6	100	91.485	Oryctolagus_cuniculus
ENSMUSG00000038290	Smg6	95	65.029	ENSORLG00000003317	smg6	74	54.075	Oryzias_latipes
ENSMUSG00000038290	Smg6	95	65.029	ENSORLG00020015343	smg6	74	53.937	Oryzias_latipes_hni
ENSMUSG00000038290	Smg6	95	65.318	ENSORLG00015020454	smg6	74	54.033	Oryzias_latipes_hsok
ENSMUSG00000038290	Smg6	97	63.610	ENSOMEG00000010838	smg6	75	53.417	Oryzias_melastigma
ENSMUSG00000038290	Smg6	100	91.761	ENSOGAG00000004483	SMG6	100	91.761	Otolemur_garnettii
ENSMUSG00000038290	Smg6	97	95.652	ENSOARG00000015076	SMG6	100	91.047	Ovis_aries
ENSMUSG00000038290	Smg6	100	91.332	ENSPPAG00000043296	SMG6	100	91.332	Pan_paniscus
ENSMUSG00000038290	Smg6	100	91.825	ENSPPRG00000014581	SMG6	100	91.825	Panthera_pardus
ENSMUSG00000038290	Smg6	98	91.841	ENSPTIG00000008925	SMG6	100	98.043	Panthera_tigris_altaica
ENSMUSG00000038290	Smg6	100	91.332	ENSPTRG00000008544	SMG6	100	97.652	Pan_troglodytes
ENSMUSG00000038290	Smg6	100	91.473	ENSPANG00000024588	SMG6	100	91.473	Papio_anubis
ENSMUSG00000038290	Smg6	97	81.556	ENSPSIG00000006660	SMG6	96	69.725	Pelodiscus_sinensis
ENSMUSG00000038290	Smg6	91	67.868	ENSPMGG00000000844	smg6	89	60.000	Periophthalmus_magnuspinnatus
ENSMUSG00000038290	Smg6	100	95.346	ENSPEMG00000020707	Smg6	98	98.253	Peromyscus_maniculatus_bairdii
ENSMUSG00000038290	Smg6	87	69.206	ENSPFOG00000012035	smg6	100	50.234	Poecilia_formosa
ENSMUSG00000038290	Smg6	87	68.889	ENSPLAG00000017660	smg6	74	53.381	Poecilia_latipinna
ENSMUSG00000038290	Smg6	87	69.206	ENSPMEG00000000258	smg6	74	53.695	Poecilia_mexicana
ENSMUSG00000038290	Smg6	87	69.206	ENSPREG00000010066	smg6	74	53.485	Poecilia_reticulata
ENSMUSG00000038290	Smg6	100	86.006	ENSPPYG00000007790	SMG6	100	86.006	Pongo_abelii
ENSMUSG00000038290	Smg6	95	91.445	ENSPCAG00000000552	SMG6	100	85.976	Procavia_capensis
ENSMUSG00000038290	Smg6	96	96.507	ENSPCOG00000020925	SMG6	100	92.107	Propithecus_coquereli
ENSMUSG00000038290	Smg6	95	93.805	ENSPVAG00000002159	SMG6	86	100.000	Pteropus_vampyrus
ENSMUSG00000038290	Smg6	96	65.352	ENSPNYG00000024151	smg6	79	56.494	Pundamilia_nyererei
ENSMUSG00000038290	Smg6	87	61.395	ENSPNAG00000015480	smg6	74	63.243	Pygocentrus_nattereri
ENSMUSG00000038290	Smg6	99	98.592	ENSRNOG00000003041	Smg6	99	98.592	Rattus_norvegicus
ENSMUSG00000038290	Smg6	100	91.473	ENSRBIG00000024746	SMG6	100	91.473	Rhinopithecus_bieti
ENSMUSG00000038290	Smg6	100	91.543	ENSRROG00000030423	SMG6	100	96.869	Rhinopithecus_roxellana
ENSMUSG00000038290	Smg6	100	91.121	ENSSBOG00000022518	SMG6	100	89.500	Saimiri_boliviensis_boliviensis
ENSMUSG00000038290	Smg6	97	90.202	ENSSHAG00000010045	SMG6	98	84.467	Sarcophilus_harrisii
ENSMUSG00000038290	Smg6	87	41.784	ENSSHAG00000000380	-	99	39.130	Sarcophilus_harrisii
ENSMUSG00000038290	Smg6	97	66.477	ENSSFOG00015005436	smg6	70	57.176	Scleropages_formosus
ENSMUSG00000038290	Smg6	96	67.042	ENSSMAG00000019777	smg6	73	54.934	Scophthalmus_maximus
ENSMUSG00000038290	Smg6	97	65.460	ENSSDUG00000016412	smg6	74	54.468	Seriola_dumerili
ENSMUSG00000038290	Smg6	97	65.460	ENSSLDG00000020747	smg6	77	53.505	Seriola_lalandi_dorsalis
ENSMUSG00000038290	Smg6	94	82.222	ENSSPUG00000007152	SMG6	99	69.386	Sphenodon_punctatus
ENSMUSG00000038290	Smg6	96	64.507	ENSSPAG00000015633	smg6	74	54.239	Stegastes_partitus
ENSMUSG00000038290	Smg6	100	90.909	ENSSSCG00000017826	SMG6	100	90.909	Sus_scrofa
ENSMUSG00000038290	Smg6	94	83.408	ENSTGUG00000005836	SMG6	100	71.980	Taeniopygia_guttata
ENSMUSG00000038290	Smg6	97	63.130	ENSTRUG00000000358	smg6	81	54.661	Takifugu_rubripes
ENSMUSG00000038290	Smg6	92	68.072	ENSTNIG00000016164	smg6	100	49.375	Tetraodon_nigroviridis
ENSMUSG00000038290	Smg6	96	97.794	ENSTBEG00000011424	SMG6	100	87.165	Tupaia_belangeri
ENSMUSG00000038290	Smg6	95	94.690	ENSTTRG00000001175	SMG6	91	91.364	Tursiops_truncatus
ENSMUSG00000038290	Smg6	100	91.491	ENSUAMG00000025152	SMG6	100	91.427	Ursus_americanus
ENSMUSG00000038290	Smg6	95	95.252	ENSUMAG00000009306	SMG6	100	91.625	Ursus_maritimus
ENSMUSG00000038290	Smg6	85	92.593	ENSVPAG00000000225	SMG6	88	92.593	Vicugna_pacos
ENSMUSG00000038290	Smg6	100	90.557	ENSVVUG00000021727	SMG6	100	90.557	Vulpes_vulpes
ENSMUSG00000038290	Smg6	97	69.164	ENSXETG00000023799	SMG6	100	59.351	Xenopus_tropicalis
ENSMUSG00000038290	Smg6	87	67.823	ENSXCOG00000009867	smg6	74	54.560	Xiphophorus_couchianus
ENSMUSG00000038290	Smg6	87	68.254	ENSXMAG00000010321	smg6	74	53.792	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21873635.	IBA	Process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	-	ISO	Process
GO:0000781	chromosome, telomeric region	-	IEA	Component
GO:0003677	DNA binding	-	IEA	Function
GO:0003723	RNA binding	-	ISO	Function
GO:0004518	nuclease activity	-	IEA	Function
GO:0004519	endonuclease activity	-	IEA	Function
GO:0004521	endoribonuclease activity	21873635.	IBA	Function
GO:0004521	endoribonuclease activity	-	ISO	Function
GO:0005634	nucleus	-	ISO	Component
GO:0005694	chromosome	-	IEA	Component
GO:0005697	telomerase holoenzyme complex	21873635.	IBA	Component
GO:0005730	nucleolus	-	ISO	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005829	cytosol	-	ISO	Component
GO:0007004	telomere maintenance via telomerase	21873635.	IBA	Process
GO:0016787	hydrolase activity	-	IEA	Function
GO:0032204	regulation of telomere maintenance	-	ISO	Process
GO:0032210	regulation of telomere maintenance via telomerase	21873635.	IBA	Process
GO:0035145	exon-exon junction complex	-	ISO	Component
GO:0042162	telomeric DNA binding	21873635.	IBA	Function
GO:0042162	telomeric DNA binding	-	ISO	Function
GO:0043021	ribonucleoprotein complex binding	21873635.	IBA	Function
GO:0043021	ribonucleoprotein complex binding	-	ISO	Function
GO:0043487	regulation of RNA stability	21873635.	IBA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0070034	telomerase RNA binding	21873635.	IBA	Function
GO:0070034	telomerase RNA binding	-	ISO	Function
GO:0070182	DNA polymerase binding	-	ISO	Function
GO:1904354	negative regulation of telomere capping	-	ISO	Process