EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Gene Ontology

Description

Ensembl ID: ENSMUSG00000040249 (Gene tree)
Gene ID: 16971
Gene Symbol: Lrp1
Alias: A2mr|CD91|b2b1554Clo
Full Name: low density lipoprotein receptor-related protein 1
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 82988
Position: chr10: 127538161-127621148
Accession: 96828
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000129877	-	550	-	-	- (aa)	-	-
ENSMUST00000135188	-	763	-	-	- (aa)	-	-
ENSMUST00000125480	-	3436	-	-	- (aa)	-	-
ENSMUST00000118455	-	2097	-	ENSMUSP00000113497	285 (aa)	-	D3Z5M3
ENSMUST00000049149	-	14888	-	ENSMUSP00000044004	4545 (aa)	-	A0A0R4J0I9
ENSMUST00000121829	-	2887	-	ENSMUSP00000113584	743 (aa)	-	Q3U5J2
ENSMUST00000145947	-	600	-	-	- (aa)	-	-
ENSMUST00000140269	-	782	-	-	- (aa)	-	-
ENSMUST00000129727	-	679	-	ENSMUSP00000120567	13 (aa)	-	F6XU19
ENSMUST00000133620	-	292	-	ENSMUSP00000115305	98 (aa)	-	F6UAC8

Gene Model

Click here to download ENSMUSG00000040249's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04979	Cholesterol metabolism	KEGG
mmu05010	Alzheimer disease	KEGG
mmu05144	Malaria	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000040249's network

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002020	protease binding	-	ISO	Function
GO:0002265	astrocyte activation involved in immune response	23152628.	IGI	Process
GO:0003279	cardiac septum development	25807483.	IMP	Process
GO:0005509	calcium ion binding	3266596.	IDA	Function
GO:0005515	protein binding	10827173.17727637.17920016.19047013.19455133.20205790.21264353.28671696.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0005768	endosome	-	ISO	Component
GO:0005769	early endosome	-	ISO	Component
GO:0005886	plasma membrane	-	IEA	Component
GO:0005887	integral component of plasma membrane	3266596.	IDA	Component
GO:0005905	clathrin-coated pit	-	IEA	Component
GO:0006897	endocytosis	-	IEA	Process
GO:0006898	receptor-mediated endocytosis	21795536.	IDA	Process
GO:0006898	receptor-mediated endocytosis	21289173.24305823.	IGI	Process
GO:0006898	receptor-mediated endocytosis	21289173.	IMP	Process
GO:0006898	receptor-mediated endocytosis	-	ISO	Process
GO:0006909	phagocytosis	-	ISO	Process
GO:0007041	lysosomal transport	26370502.	IDA	Process
GO:0007204	positive regulation of cytosolic calcium ion concentration	-	ISO	Process
GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	-	ISO	Process
GO:0007275	multicellular organism development	-	IEA	Process
GO:0008203	cholesterol metabolic process	17920016.	IMP	Process
GO:0008283	cell proliferation	-	ISO	Process
GO:0010812	negative regulation of cell-substrate adhesion	-	ISO	Process
GO:0010875	positive regulation of cholesterol efflux	19718435.	IMP	Process
GO:0010942	positive regulation of cell death	-	ISO	Process
GO:0010976	positive regulation of neuron projection development	-	ISO	Process
GO:0010977	negative regulation of neuron projection development	-	ISO	Process
GO:0014912	negative regulation of smooth muscle cell migration	19742316.	IMP	Process
GO:0015026	coreceptor activity	-	ISO	Function
GO:0016020	membrane	15082773.	IDA	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0016323	basolateral plasma membrane	-	ISO	Component
GO:0016964	alpha-2 macroglobulin receptor activity	-	ISO	Function
GO:0030136	clathrin-coated vesicle	-	ISO	Component
GO:0030178	negative regulation of Wnt signaling pathway	16207730.	IDA	Process
GO:0030425	dendrite	-	ISO	Component
GO:0032050	clathrin heavy chain binding	-	ISO	Function
GO:0032092	positive regulation of protein binding	-	ISO	Process
GO:0032370	positive regulation of lipid transport	19718435.	IMP	Process
GO:0032374	regulation of cholesterol transport	19718435.	IMP	Process
GO:0032429	regulation of phospholipase A2 activity	19718435.	IMP	Process
GO:0032593	insulin-responsive compartment	-	ISO	Component
GO:0032956	regulation of actin cytoskeleton organization	19742316.	IMP	Process
GO:0034185	apolipoprotein binding	-	ISO	Function
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	-	ISO	Process
GO:0035909	aorta morphogenesis	19742316.	IMP	Process
GO:0038024	cargo receptor activity	21289173.	IMP	Function
GO:0038024	cargo receptor activity	-	ISO	Function
GO:0043025	neuronal cell body	-	ISO	Component
GO:0043066	negative regulation of apoptotic process	-	ISO	Process
GO:0043235	receptor complex	23382219.	ISO	Component
GO:0043277	apoptotic cell clearance	15647754.	IMP	Process
GO:0043524	negative regulation of neuron apoptotic process	-	ISO	Process
GO:0044242	cellular lipid catabolic process	-	ISO	Process
GO:0044295	axonal growth cone	-	ISO	Component
GO:0044877	protein-containing complex binding	-	ISO	Function
GO:0045177	apical part of cell	-	ISO	Component
GO:0045773	positive regulation of axon extension	-	ISO	Process
GO:0045807	positive regulation of endocytosis	-	ISO	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0048471	perinuclear region of cytoplasm	19047013.	ISO	Component
GO:0048691	positive regulation of axon extension involved in regeneration	-	ISO	Process
GO:0048694	positive regulation of collateral sprouting of injured axon	-	ISO	Process
GO:0050766	positive regulation of phagocytosis	-	ISO	Process
GO:0051222	positive regulation of protein transport	-	ISO	Process
GO:0051481	negative regulation of cytosolic calcium ion concentration	-	ISO	Process
GO:0051895	negative regulation of focal adhesion assembly	-	ISO	Process
GO:0060548	negative regulation of cell death	-	ISO	Process
GO:0060976	coronary vasculature development	25807483.	IMP	Process
GO:0061642	chemoattraction of axon	-	ISO	Process
GO:0070374	positive regulation of ERK1 and ERK2 cascade	-	ISO	Process
GO:0097242	amyloid-beta clearance	19098903.	IMP	Process
GO:0150093	amyloid-beta clearance by transcytosis	-	ISO	Process
GO:0150094	amyloid-beta clearance by cellular catabolic process	21289173.	IDA	Process
GO:0150094	amyloid-beta clearance by cellular catabolic process	24305823.	IGI	Process
GO:0150094	amyloid-beta clearance by cellular catabolic process	23152628.	IMP	Process
GO:0150094	amyloid-beta clearance by cellular catabolic process	-	ISO	Process
GO:1900149	positive regulation of Schwann cell migration	-	ISO	Process
GO:1903078	positive regulation of protein localization to plasma membrane	-	ISO	Process
GO:1904109	positive regulation of cholesterol import	-	ISO	Process
GO:1904209	positive regulation of chemokine (C-C motif) ligand 2 secretion	-	ISO	Process
GO:1904646	cellular response to amyloid-beta	23152628.	IGI	Process
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	-	ISO	Process
GO:1905167	positive regulation of lysosomal protein catabolic process	-	ISO	Process
GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	19742316.	IMP	Process