EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000040423 (Gene tree)
Gene ID: 381305
Gene Symbol: Rc3h1
Alias: 5730557L09Rik|roquin
Full Name: RING CCCH (C3H) domains 1
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Plus strand
Length: 68561 bases
Position: chr1:160906418-160974978
Accession: 2685397
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000037178	zf-CCCH	PF00642.24	0.00047	1	1
ENSMUSP00000124871	zf-CCCH	PF00642.24	0.00048	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000035911	-	3476	-	ENSMUSP00000037178	1121 (aa)	-	H7BX02
ENSMUST00000161708	-	663	-	-	- (aa)	-	-
ENSMUST00000161609	-	11006	XM_006496908	ENSMUSP00000124871	1130 (aa)	XP_006496971	Q4VGL6

Gene Model

Click here to download ENSMUSG00000040423's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000040423's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSMUSG00000040423	Rc3h1	92	54.296	ENSMUSG00000075376	Rc3h2	98	80.892

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000040423	Rc3h1	100	93.204	ENSG00000135870	RC3H1	100	93.645	Homo_sapiens
ENSMUSG00000040423	Rc3h1	100	93.551	ENSAMEG00000015657	RC3H1	100	93.551	Ailuropoda_melanoleuca
ENSMUSG00000040423	Rc3h1	100	85.677	ENSAPLG00000005341	RC3H1	100	85.677	Anas_platyrhynchos
ENSMUSG00000040423	Rc3h1	100	82.955	ENSACAG00000015271	RC3H1	100	83.129	Anolis_carolinensis
ENSMUSG00000040423	Rc3h1	100	93.204	ENSANAG00000036716	RC3H1	100	93.733	Aotus_nancymaae
ENSMUSG00000040423	Rc3h1	100	92.349	ENSBTAG00000052708	RC3H1	100	92.794	Bos_taurus
ENSMUSG00000040423	Rc3h1	100	93.116	ENSCJAG00000009106	RC3H1	100	93.645	Callithrix_jacchus
ENSMUSG00000040423	Rc3h1	100	93.198	ENSCAFG00000014434	RC3H1	100	93.640	Canis_familiaris
ENSMUSG00000040423	Rc3h1	100	93.116	ENSCAFG00020017112	RC3H1	99	97.978	Canis_lupus_dingo
ENSMUSG00000040423	Rc3h1	100	92.698	ENSCHIG00000002873	RC3H1	100	93.143	Capra_hircus
ENSMUSG00000040423	Rc3h1	99	91.873	ENSTSYG00000003913	RC3H1	99	92.226	Carlito_syrichta
ENSMUSG00000040423	Rc3h1	100	89.488	ENSCPOG00000004349	RC3H1	100	89.488	Cavia_porcellus
ENSMUSG00000040423	Rc3h1	100	91.527	ENSCCAG00000025652	RC3H1	100	92.056	Cebus_capucinus
ENSMUSG00000040423	Rc3h1	100	93.292	ENSCATG00000033497	RC3H1	100	93.733	Cercocebus_atys
ENSMUSG00000040423	Rc3h1	100	91.792	ENSCLAG00000011267	RC3H1	100	92.145	Chinchilla_lanigera
ENSMUSG00000040423	Rc3h1	96	93.370	ENSCSAG00000011823	RC3H1	85	93.831	Chlorocebus_sabaeus
ENSMUSG00000040423	Rc3h1	100	87.357	ENSCPBG00000014670	RC3H1	100	87.094	Chrysemys_picta_bellii
ENSMUSG00000040423	Rc3h1	100	93.298	ENSCANG00000032120	RC3H1	100	93.739	Colobus_angolensis_palliatus
ENSMUSG00000040423	Rc3h1	100	95.841	ENSCGRG00001020812	Rc3h1	100	95.841	Cricetulus_griseus_chok1gshd
ENSMUSG00000040423	Rc3h1	100	95.841	ENSCGRG00000011952	Rc3h1	100	95.841	Cricetulus_griseus_crigri
ENSMUSG00000040423	Rc3h1	55	90.000	ENSDNOG00000011494	RC3H1	99	90.806	Dasypus_novemcinctus
ENSMUSG00000040423	Rc3h1	100	92.580	ENSDORG00000004855	Rc3h1	100	92.491	Dipodomys_ordii
ENSMUSG00000040423	Rc3h1	82	93.878	ENSETEG00000012064	RC3H1	87	93.878	Echinops_telfairi
ENSMUSG00000040423	Rc3h1	100	92.342	ENSEASG00005017000	RC3H1	100	92.698	Equus_asinus_asinus
ENSMUSG00000040423	Rc3h1	100	92.164	ENSECAG00000021208	RC3H1	100	92.520	Equus_caballus
ENSMUSG00000040423	Rc3h1	89	81.818	ENSEEUG00000014861	RC3H1	93	81.818	Erinaceus_europaeus
ENSMUSG00000040423	Rc3h1	100	93.292	ENSFCAG00000014924	RC3H1	100	93.733	Felis_catus
ENSMUSG00000040423	Rc3h1	100	85.039	ENSFALG00000002947	RC3H1	100	85.039	Ficedula_albicollis
ENSMUSG00000040423	Rc3h1	100	92.233	ENSFDAG00000013303	RC3H1	100	92.498	Fukomys_damarensis
ENSMUSG00000040423	Rc3h1	100	85.651	ENSGALG00000004587	RC3H1	100	85.651	Gallus_gallus
ENSMUSG00000040423	Rc3h1	100	86.472	ENSGAGG00000018194	RC3H1	100	86.472	Gopherus_agassizii
ENSMUSG00000040423	Rc3h1	100	86.544	ENSGGOG00000005735	RC3H1	100	86.983	Gorilla_gorilla
ENSMUSG00000040423	Rc3h1	88	86.604	ENSHGLG00000004183	-	100	86.604	Heterocephalus_glaber_female
ENSMUSG00000040423	Rc3h1	100	91.439	ENSHGLG00100008577	RC3H1	100	91.792	Heterocephalus_glaber_male
ENSMUSG00000040423	Rc3h1	100	92.845	ENSSTOG00000016033	RC3H1	100	93.286	Ictidomys_tridecemlineatus
ENSMUSG00000040423	Rc3h1	100	92.661	ENSJJAG00000018915	Rc3h1	100	92.573	Jaculus_jaculus
ENSMUSG00000040423	Rc3h1	100	74.019	ENSLACG00000016186	RC3H1	100	77.941	Latimeria_chalumnae
ENSMUSG00000040423	Rc3h1	97	93.437	ENSLAFG00000004367	RC3H1	100	93.892	Loxodonta_africana
ENSMUSG00000040423	Rc3h1	100	93.204	ENSMFAG00000033725	RC3H1	100	93.645	Macaca_fascicularis
ENSMUSG00000040423	Rc3h1	100	93.292	ENSMMUG00000000630	RC3H1	100	93.733	Macaca_mulatta
ENSMUSG00000040423	Rc3h1	100	93.292	ENSMNEG00000035968	RC3H1	100	93.733	Macaca_nemestrina
ENSMUSG00000040423	Rc3h1	100	93.204	ENSMLEG00000037455	RC3H1	100	93.645	Mandrillus_leucophaeus
ENSMUSG00000040423	Rc3h1	97	96.162	ENSMAUG00000020864	Rc3h1	100	96.162	Mesocricetus_auratus
ENSMUSG00000040423	Rc3h1	100	93.110	ENSMICG00000003000	RC3H1	100	93.551	Microcebus_murinus
ENSMUSG00000040423	Rc3h1	93	95.442	ENSMOCG00000016587	Rc3h1	98	95.442	Microtus_ochrogaster
ENSMUSG00000040423	Rc3h1	100	89.330	ENSMODG00000004289	RC3H1	100	89.418	Monodelphis_domestica
ENSMUSG00000040423	Rc3h1	100	99.115	MGP_CAROLIEiJ_G0014756	Rc3h1	100	99.115	Mus_caroli
ENSMUSG00000040423	Rc3h1	100	98.673	MGP_PahariEiJ_G0027992	Rc3h1	100	98.673	Mus_pahari
ENSMUSG00000040423	Rc3h1	100	99.469	MGP_SPRETEiJ_G0015563	Rc3h1	100	99.469	Mus_spretus
ENSMUSG00000040423	Rc3h1	100	93.375	ENSMPUG00000004747	RC3H1	100	93.375	Mustela_putorius_furo
ENSMUSG00000040423	Rc3h1	100	91.954	ENSMLUG00000011127	RC3H1	100	92.396	Myotis_lucifugus
ENSMUSG00000040423	Rc3h1	100	95.310	ENSNGAG00000011135	Rc3h1	100	95.310	Nannospalax_galili
ENSMUSG00000040423	Rc3h1	100	93.292	ENSNLEG00000015327	RC3H1	100	93.733	Nomascus_leucogenys
ENSMUSG00000040423	Rc3h1	99	80.177	ENSOPRG00000013068	RC3H1	99	80.177	Ochotona_princeps
ENSMUSG00000040423	Rc3h1	100	92.233	ENSODEG00000014185	RC3H1	100	92.233	Octodon_degus
ENSMUSG00000040423	Rc3h1	100	88.646	ENSOANG00000000924	RC3H1	100	88.821	Ornithorhynchus_anatinus
ENSMUSG00000040423	Rc3h1	99	92.652	ENSOCUG00000004930	RC3H1	98	93.100	Oryctolagus_cuniculus
ENSMUSG00000040423	Rc3h1	100	85.979	ENSOGAG00000004044	RC3H1	100	86.332	Otolemur_garnettii
ENSMUSG00000040423	Rc3h1	100	92.105	ENSOARG00000013011	RC3H1	100	92.544	Ovis_aries
ENSMUSG00000040423	Rc3h1	100	93.210	ENSPPAG00000039253	RC3H1	100	93.651	Pan_paniscus
ENSMUSG00000040423	Rc3h1	100	93.321	ENSPPRG00000009007	RC3H1	100	93.767	Panthera_pardus
ENSMUSG00000040423	Rc3h1	100	92.876	ENSPTIG00000015326	RC3H1	100	93.404	Panthera_tigris_altaica
ENSMUSG00000040423	Rc3h1	100	93.210	ENSPTRG00000001702	RC3H1	100	93.651	Pan_troglodytes
ENSMUSG00000040423	Rc3h1	100	93.204	ENSPANG00000008886	RC3H1	100	93.645	Papio_anubis
ENSMUSG00000040423	Rc3h1	100	87.710	ENSPSIG00000016181	RC3H1	100	87.975	Pelodiscus_sinensis
ENSMUSG00000040423	Rc3h1	100	95.398	ENSPEMG00000011966	Rc3h1	100	95.487	Peromyscus_maniculatus_bairdii
ENSMUSG00000040423	Rc3h1	70	92.776	ENSPCIG00000002058	RC3H1	95	98.206	Phascolarctos_cinereus
ENSMUSG00000040423	Rc3h1	100	90.556	ENSPPYG00000000490	RC3H1	98	93.919	Pongo_abelii
ENSMUSG00000040423	Rc3h1	81	97.368	ENSPCAG00000010775	RC3H1	87	97.368	Procavia_capensis
ENSMUSG00000040423	Rc3h1	83	91.658	ENSPCOG00000021795	RC3H1	96	92.193	Propithecus_coquereli
ENSMUSG00000040423	Rc3h1	100	84.629	ENSPVAG00000007593	RC3H1	100	84.982	Pteropus_vampyrus
ENSMUSG00000040423	Rc3h1	97	61.408	ENSPNAG00000023439	rc3h1a	95	90.766	Pygocentrus_nattereri
ENSMUSG00000040423	Rc3h1	100	93.386	ENSRBIG00000037743	RC3H1	100	93.827	Rhinopithecus_bieti
ENSMUSG00000040423	Rc3h1	100	93.380	ENSRROG00000036546	RC3H1	100	93.822	Rhinopithecus_roxellana
ENSMUSG00000040423	Rc3h1	93	88.252	ENSSBOG00000010664	RC3H1	100	88.730	Saimiri_boliviensis_boliviensis
ENSMUSG00000040423	Rc3h1	100	88.634	ENSSHAG00000007589	RC3H1	100	88.722	Sarcophilus_harrisii
ENSMUSG00000040423	Rc3h1	87	86.712	ENSSARG00000004660	RC3H1	86	86.712	Sorex_araneus
ENSMUSG00000040423	Rc3h1	100	81.770	ENSSPUG00000018472	RC3H1	100	82.281	Sphenodon_punctatus
ENSMUSG00000040423	Rc3h1	100	93.551	ENSSSCG00000015498	RC3H1	100	93.993	Sus_scrofa
ENSMUSG00000040423	Rc3h1	100	85.664	ENSTGUG00000004090	RC3H1	100	85.664	Taeniopygia_guttata
ENSMUSG00000040423	Rc3h1	89	94.823	ENSTBEG00000005015	RC3H1	89	94.823	Tupaia_belangeri
ENSMUSG00000040423	Rc3h1	100	92.335	ENSTTRG00000008572	RC3H1	100	92.775	Tursiops_truncatus
ENSMUSG00000040423	Rc3h1	100	93.198	ENSUAMG00000019525	RC3H1	100	93.198	Ursus_americanus
ENSMUSG00000040423	Rc3h1	100	93.645	ENSUMAG00000020087	RC3H1	100	93.645	Ursus_maritimus
ENSMUSG00000040423	Rc3h1	91	98.423	ENSVPAG00000002591	RC3H1	92	98.423	Vicugna_pacos
ENSMUSG00000040423	Rc3h1	100	92.870	ENSVVUG00000014201	RC3H1	100	93.310	Vulpes_vulpes
ENSMUSG00000040423	Rc3h1	100	77.304	ENSXETG00000020030	rc3h1	100	77.217	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000209	protein polyubiquitination	-	ISO	Process
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	26000482.26255671.	IMP	Process
GO:0000932	P-body	20639877.26000482.26255671.	IDA	Component
GO:0000956	nuclear-transcribed mRNA catabolic process	20639877.	IMP	Process
GO:0000956	nuclear-transcribed mRNA catabolic process	-	ISO	Process
GO:0001782	B cell homeostasis	23583643.	IGI	Process
GO:0002634	regulation of germinal center formation	15917799.19217324.	IMP	Process
GO:0002635	negative regulation of germinal center formation	18172933.	IMP	Process
GO:0003723	RNA binding	-	IEA	Function
GO:0003725	double-stranded RNA binding	-	ISO	Function
GO:0003729	mRNA binding	23583643.	IDA	Function
GO:0003730	mRNA 3'-UTR binding	20639877.26000482.26255671.	IDA	Function
GO:0004842	ubiquitin-protein transferase activity	-	ISO	Function
GO:0005515	protein binding	20639877.23583643.25697406.	IPI	Function
GO:0005737	cytoplasm	15917799.	IDA	Component
GO:0008270	zinc ion binding	25697406.	IDA	Function
GO:0010468	regulation of gene expression	23583643.	IDA	Process
GO:0010494	cytoplasmic stress granule	15917799.20639877.26000482.26255671.	IDA	Component
GO:0010608	posttranscriptional regulation of gene expression	23583643.	IDA	Process
GO:0010608	posttranscriptional regulation of gene expression	20639877.25026077.	IMP	Process
GO:0016740	transferase activity	-	IEA	Function
GO:0030889	negative regulation of B cell proliferation	18172933.	IMP	Process
GO:0033962	cytoplasmic mRNA processing body assembly	20639877.	IMP	Process
GO:0035198	miRNA binding	25697406.	IDA	Function
GO:0035613	RNA stem-loop binding	25026077.26000482.26255671.	IDA	Function
GO:0035613	RNA stem-loop binding	-	ISO	Function
GO:0042098	T cell proliferation	23583643.	IGI	Process
GO:0042129	regulation of T cell proliferation	-	IEA	Process
GO:0043029	T cell homeostasis	23583643.	IGI	Process
GO:0043488	regulation of mRNA stability	18172933.	IMP	Process
GO:0045623	negative regulation of T-helper cell differentiation	15917799.	IMP	Process
GO:0046007	negative regulation of activated T cell proliferation	18172933.	IMP	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0048535	lymph node development	23583643.	IGI	Process
GO:0048536	spleen development	23583643.	IGI	Process
GO:0050852	T cell receptor signaling pathway	25282160.	IMP	Process
GO:0050856	regulation of T cell receptor signaling pathway	15917799.	IMP	Process
GO:0050863	regulation of T cell activation	-	IEA	Process
GO:0061014	positive regulation of mRNA catabolic process	26000482.26255671.	IDA	Process
GO:0061014	positive regulation of mRNA catabolic process	25026077.	IMP	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	26000482.26255671.	IDA	Process
GO:0061470	T follicular helper cell differentiation	23583643.	IGI	Process
GO:0071347	cellular response to interleukin-1	26255671.	IDA	Process
GO:1901224	positive regulation of NIK/NF-kappaB signaling	23583643.	IDA	Process
GO:2000320	negative regulation of T-helper 17 cell differentiation	25282160.	IMP	Process
GO:2000628	regulation of miRNA metabolic process	25697406.	IMP	Process