EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000040761 (Gene tree)
Gene ID: 56381
Gene Symbol: Spen
Alias: Mint
Full Name: spen family transcription repressor
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Minus strand
Length: 70708 bases
Position: chr4:141467890-141538597
Accession: 1891706
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000077925	RRM_5	PF13893.6	1.8e-07	1	2
ENSMUSP00000077925	RRM_5	PF13893.6	1.8e-07	2	2
ENSMUSP00000101412	RRM_5	PF13893.6	1.9e-07	1	2
ENSMUSP00000101412	RRM_5	PF13893.6	1.9e-07	2	2
ENSMUSP00000077925	RRM_1	PF00076.22	1.1e-43	1	4
ENSMUSP00000077925	RRM_1	PF00076.22	1.1e-43	2	4
ENSMUSP00000077925	RRM_1	PF00076.22	1.1e-43	3	4
ENSMUSP00000077925	RRM_1	PF00076.22	1.1e-43	4	4
ENSMUSP00000101412	RRM_1	PF00076.22	1.2e-43	1	4
ENSMUSP00000101412	RRM_1	PF00076.22	1.2e-43	2	4
ENSMUSP00000101412	RRM_1	PF00076.22	1.2e-43	3	4
ENSMUSP00000101412	RRM_1	PF00076.22	1.2e-43	4	4

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000144500	-	435	-	-	- (aa)	-	-
ENSMUST00000078886	-	12082	XM_006539070	ENSMUSP00000077925	3620 (aa)	XP_006539133	A2ADB1
ENSMUST00000152081	-	680	-	-	- (aa)	-	-
ENSMUST00000147227	-	481	-	-	- (aa)	-	-
ENSMUST00000152411	-	1514	-	-	- (aa)	-	-
ENSMUST00000105786	-	12299	XM_006539069	ENSMUSP00000101412	3643 (aa)	XP_006539132	A2ADB0

Gene Model

Click here to download ENSMUSG00000040761's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000040761's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000040761	Spen	100	80.445	ENSG00000065526	SPEN	99	96.990	Homo_sapiens
ENSMUSG00000040761	Spen	87	81.461	ENSAPOG00000009853	-	91	75.281	Acanthochromis_polyacanthus
ENSMUSG00000040761	Spen	77	80.556	ENSAPOG00000011411	si:ch1073-335m2.2	77	80.556	Acanthochromis_polyacanthus
ENSMUSG00000040761	Spen	100	79.167	ENSAMEG00000011817	SPEN	100	78.933	Ailuropoda_melanoleuca
ENSMUSG00000040761	Spen	69	74.306	ENSAOCG00000008077	si:ch1073-335m2.2	74	74.306	Amphiprion_ocellaris
ENSMUSG00000040761	Spen	87	81.461	ENSAOCG00000014505	-	81	51.262	Amphiprion_ocellaris
ENSMUSG00000040761	Spen	87	81.461	ENSAPEG00000010288	-	81	51.100	Amphiprion_percula
ENSMUSG00000040761	Spen	79	74.306	ENSAPEG00000013515	si:ch1073-335m2.2	76	80.556	Amphiprion_percula
ENSMUSG00000040761	Spen	89	82.584	ENSATEG00000005627	-	90	48.625	Anabas_testudineus
ENSMUSG00000040761	Spen	65	78.307	ENSATEG00000007674	si:ch1073-335m2.2	61	78.307	Anabas_testudineus
ENSMUSG00000040761	Spen	97	65.503	ENSAPLG00000012618	SPEN	100	65.602	Anas_platyrhynchos
ENSMUSG00000040761	Spen	97	60.668	ENSACAG00000013761	SPEN	99	61.041	Anolis_carolinensis
ENSMUSG00000040761	Spen	99	79.533	ENSANAG00000034428	SPEN	99	79.024	Aotus_nancymaae
ENSMUSG00000040761	Spen	97	81.461	ENSACLG00000016922	-	90	48.093	Astatotilapia_calliptera
ENSMUSG00000040761	Spen	89	82.682	ENSAMXG00000012485	spen	89	47.706	Astyanax_mexicanus
ENSMUSG00000040761	Spen	100	78.676	ENSBTAG00000018729	SPEN	100	78.459	Bos_taurus
ENSMUSG00000040761	Spen	100	79.595	ENSCJAG00000008527	SPEN	100	79.024	Callithrix_jacchus
ENSMUSG00000040761	Spen	88	77.122	ENSCAFG00000016132	-	98	76.639	Canis_familiaris
ENSMUSG00000040761	Spen	100	79.606	ENSCHIG00000025070	SPEN	100	78.988	Capra_hircus
ENSMUSG00000040761	Spen	92	78.216	ENSTSYG00000036016	SPEN	99	77.679	Carlito_syrichta
ENSMUSG00000040761	Spen	99	76.828	ENSCAPG00000013803	SPEN	100	76.600	Cavia_aperea
ENSMUSG00000040761	Spen	99	75.165	ENSCPOG00000014036	SPEN	100	75.357	Cavia_porcellus
ENSMUSG00000040761	Spen	100	75.338	ENSCCAG00000020258	SPEN	99	76.791	Cebus_capucinus
ENSMUSG00000040761	Spen	95	97.778	ENSCATG00000015079	SPEN	99	97.059	Cercocebus_atys
ENSMUSG00000040761	Spen	99	77.327	ENSCLAG00000002018	SPEN	100	76.932	Chinchilla_lanigera
ENSMUSG00000040761	Spen	100	80.488	ENSCSAG00000000841	SPEN	100	80.109	Chlorocebus_sabaeus
ENSMUSG00000040761	Spen	99	78.907	ENSCANG00000034547	SPEN	99	78.418	Colobus_angolensis_palliatus
ENSMUSG00000040761	Spen	99	86.753	ENSCGRG00001007725	Spen	100	86.608	Cricetulus_griseus_chok1gshd
ENSMUSG00000040761	Spen	99	85.805	ENSCGRG00000010581	Spen	100	85.520	Cricetulus_griseus_crigri
ENSMUSG00000040761	Spen	97	84.270	ENSCSEG00000003915	-	90	48.296	Cynoglossus_semilaevis
ENSMUSG00000040761	Spen	86	62.825	ENSCVAG00000009075	si:ch1073-335m2.2	90	62.825	Cyprinodon_variegatus
ENSMUSG00000040761	Spen	97	45.023	ENSCVAG00000016346	-	90	48.361	Cyprinodon_variegatus
ENSMUSG00000040761	Spen	84	66.935	ENSDARG00000074245	spen	100	88.148	Danio_rerio
ENSMUSG00000040761	Spen	73	63.821	ENSDARG00000074332	si:ch1073-335m2.2	81	63.821	Danio_rerio
ENSMUSG00000040761	Spen	100	78.345	ENSDNOG00000041948	SPEN	100	78.075	Dasypus_novemcinctus
ENSMUSG00000040761	Spen	99	76.726	ENSDORG00000023909	Spen	99	76.671	Dipodomys_ordii
ENSMUSG00000040761	Spen	68	95.378	ENSETEG00000016692	-	67	95.397	Echinops_telfairi
ENSMUSG00000040761	Spen	95	97.778	ENSEASG00005015911	SPEN	99	97.778	Equus_asinus_asinus
ENSMUSG00000040761	Spen	95	97.778	ENSECAG00000008833	SPEN	99	97.778	Equus_caballus
ENSMUSG00000040761	Spen	72	95.349	ENSEEUG00000010255	SPEN	76	95.349	Erinaceus_europaeus
ENSMUSG00000040761	Spen	71	76.923	ENSELUG00000007726	si:ch1073-335m2.2	78	76.923	Esox_lucius
ENSMUSG00000040761	Spen	99	76.335	ENSFDAG00000010212	SPEN	100	76.260	Fukomys_damarensis
ENSMUSG00000040761	Spen	62	80.791	ENSFHEG00000004544	si:ch1073-335m2.2	66	80.791	Fundulus_heteroclitus
ENSMUSG00000040761	Spen	91	77.249	ENSGMOG00000008156	si:ch1073-335m2.2	65	77.249	Gadus_morhua
ENSMUSG00000040761	Spen	65	77.114	ENSGMOG00000008397	-	64	77.114	Gadus_morhua
ENSMUSG00000040761	Spen	74	74.752	ENSGAFG00000021570	si:ch1073-335m2.2	79	68.398	Gambusia_affinis
ENSMUSG00000040761	Spen	97	44.292	ENSGAFG00000015819	-	91	74.157	Gambusia_affinis
ENSMUSG00000040761	Spen	69	58.395	ENSGACG00000005341	-	70	58.395	Gasterosteus_aculeatus
ENSMUSG00000040761	Spen	80	81.176	ENSGACG00000001176	si:ch1073-335m2.2	81	81.176	Gasterosteus_aculeatus
ENSMUSG00000040761	Spen	98	94.737	ENSGAGG00000020785	SPEN	100	94.152	Gopherus_agassizii
ENSMUSG00000040761	Spen	100	80.244	ENSGGOG00000012041	SPEN	100	79.534	Gorilla_gorilla
ENSMUSG00000040761	Spen	75	77.041	ENSHBUG00000023253	si:ch1073-335m2.2	74	76.263	Haplochromis_burtoni
ENSMUSG00000040761	Spen	97	81.461	ENSHBUG00000020626	-	90	48.301	Haplochromis_burtoni
ENSMUSG00000040761	Spen	89	77.419	ENSHGLG00100019294	SPEN	95	77.302	Heterocephalus_glaber_male
ENSMUSG00000040761	Spen	75	67.647	ENSHCOG00000006004	si:ch1073-335m2.2	76	79.104	Hippocampus_comes
ENSMUSG00000040761	Spen	97	82.222	ENSIPUG00000021668	spen	80	81.421	Ictalurus_punctatus
ENSMUSG00000040761	Spen	74	67.464	ENSIPUG00000018212	si:ch1073-335m2.2	75	67.464	Ictalurus_punctatus
ENSMUSG00000040761	Spen	99	81.114	ENSSTOG00000021428	SPEN	100	80.712	Ictidomys_tridecemlineatus
ENSMUSG00000040761	Spen	100	80.327	ENSJJAG00000010882	Spen	100	79.782	Jaculus_jaculus
ENSMUSG00000040761	Spen	72	80.000	ENSKMAG00000021725	si:ch1073-335m2.2	75	80.000	Kryptolebias_marmoratus
ENSMUSG00000040761	Spen	97	80.337	ENSKMAG00000003882	-	69	56.062	Kryptolebias_marmoratus
ENSMUSG00000040761	Spen	83	40.772	ENSLBEG00000019129	-	65	46.525	Labrus_bergylta
ENSMUSG00000040761	Spen	85	62.252	ENSLACG00000003258	SPEN	89	62.252	Latimeria_chalumnae
ENSMUSG00000040761	Spen	97	51.728	ENSLOCG00000007896	si:ch1073-335m2.2	99	52.068	Lepisosteus_oculatus
ENSMUSG00000040761	Spen	99	78.143	ENSLAFG00000004524	SPEN	100	77.739	Loxodonta_africana
ENSMUSG00000040761	Spen	100	80.098	ENSMFAG00000041974	SPEN	100	79.881	Macaca_fascicularis
ENSMUSG00000040761	Spen	100	80.163	ENSMMUG00000008026	SPEN	100	79.935	Macaca_mulatta
ENSMUSG00000040761	Spen	100	80.195	ENSMNEG00000042402	SPEN	100	80.087	Macaca_nemestrina
ENSMUSG00000040761	Spen	100	79.826	ENSMLEG00000039293	SPEN	99	79.555	Mandrillus_leucophaeus
ENSMUSG00000040761	Spen	79	83.832	ENSMAMG00000023870	si:ch1073-335m2.2	75	83.832	Mastacembelus_armatus
ENSMUSG00000040761	Spen	88	41.217	ENSMZEG00005021491	-	88	44.266	Maylandia_zebra
ENSMUSG00000040761	Spen	100	84.502	ENSMAUG00000008318	Spen	100	84.529	Mesocricetus_auratus
ENSMUSG00000040761	Spen	100	79.605	ENSMICG00000030994	SPEN	100	79.376	Microcebus_murinus
ENSMUSG00000040761	Spen	100	87.106	ENSMOCG00000016083	Spen	100	87.078	Microtus_ochrogaster
ENSMUSG00000040761	Spen	53	77.907	ENSMMOG00000021742	si:ch1073-335m2.2	51	77.907	Mola_mola
ENSMUSG00000040761	Spen	97	82.022	ENSMALG00000008625	-	81	51.439	Monopterus_albus
ENSMUSG00000040761	Spen	100	97.874	MGP_CAROLIEiJ_G0026745	Spen	100	97.874	Mus_caroli
ENSMUSG00000040761	Spen	100	94.598	MGP_PahariEiJ_G0029076	Spen	100	94.460	Mus_pahari
ENSMUSG00000040761	Spen	100	98.766	MGP_SPRETEiJ_G0027724	Spen	100	98.766	Mus_spretus
ENSMUSG00000040761	Spen	98	78.872	ENSMPUG00000016317	SPEN	100	78.520	Mustela_putorius_furo
ENSMUSG00000040761	Spen	94	77.366	ENSMLUG00000010144	SPEN	99	94.340	Myotis_lucifugus
ENSMUSG00000040761	Spen	100	77.102	ENSNGAG00000000641	Spen	99	81.327	Nannospalax_galili
ENSMUSG00000040761	Spen	68	77.041	ENSNBRG00000005733	si:ch1073-335m2.2	69	77.041	Neolamprologus_brichardi
ENSMUSG00000040761	Spen	83	41.083	ENSNBRG00000022090	-	88	41.090	Neolamprologus_brichardi
ENSMUSG00000040761	Spen	99	80.213	ENSNLEG00000007652	SPEN	99	79.711	Nomascus_leucogenys
ENSMUSG00000040761	Spen	88	93.750	ENSMEUG00000002422	SPEN	90	93.750	Notamacropus_eugenii
ENSMUSG00000040761	Spen	93	83.119	ENSOPRG00000015800	SPEN	92	83.372	Ochotona_princeps
ENSMUSG00000040761	Spen	100	77.271	ENSODEG00000016644	SPEN	100	76.805	Octodon_degus
ENSMUSG00000040761	Spen	99	77.007	ENSOCUG00000010840	SPEN	99	77.009	Oryctolagus_cuniculus
ENSMUSG00000040761	Spen	82	76.190	ENSORLG00000018414	si:ch1073-335m2.2	78	62.698	Oryzias_latipes
ENSMUSG00000040761	Spen	66	77.157	ENSORLG00000028894	-	63	77.157	Oryzias_latipes
ENSMUSG00000040761	Spen	81	76.190	ENSORLG00020009351	si:ch1073-335m2.2	78	62.698	Oryzias_latipes_hni
ENSMUSG00000040761	Spen	66	77.157	ENSORLG00020007735	-	63	77.157	Oryzias_latipes_hni
ENSMUSG00000040761	Spen	62	77.157	ENSORLG00015022085	-	64	77.157	Oryzias_latipes_hsok
ENSMUSG00000040761	Spen	73	65.607	ENSOMEG00000004509	si:ch1073-335m2.2	79	64.286	Oryzias_melastigma
ENSMUSG00000040761	Spen	86	84.884	ENSOMEG00000007639	-	77	84.884	Oryzias_melastigma
ENSMUSG00000040761	Spen	100	80.027	ENSOGAG00000025110	SPEN	100	79.512	Otolemur_garnettii
ENSMUSG00000040761	Spen	99	78.776	ENSOARG00000008477	SPEN	99	78.356	Ovis_aries
ENSMUSG00000040761	Spen	99	80.159	ENSPPAG00000035690	SPEN	100	79.416	Pan_paniscus
ENSMUSG00000040761	Spen	100	80.309	ENSPTRG00000000210	SPEN	100	79.545	Pan_troglodytes
ENSMUSG00000040761	Spen	100	79.176	ENSPANG00000006293	SPEN	100	78.905	Papio_anubis
ENSMUSG00000040761	Spen	94	100.000	ENSPKIG00000010492	si:ch1073-335m2.2	89	100.000	Paramormyrops_kingsleyae
ENSMUSG00000040761	Spen	84	83.511	ENSPKIG00000002617	SPEN	91	80.370	Paramormyrops_kingsleyae
ENSMUSG00000040761	Spen	97	64.978	ENSPSIG00000008026	SPEN	100	64.751	Pelodiscus_sinensis
ENSMUSG00000040761	Spen	99	87.517	ENSPEMG00000022997	Spen	100	87.517	Peromyscus_maniculatus_bairdii
ENSMUSG00000040761	Spen	70	75.743	ENSPLAG00000016625	si:ch1073-335m2.2	77	75.743	Poecilia_latipinna
ENSMUSG00000040761	Spen	97	44.202	ENSPMEG00000006764	-	91	73.783	Poecilia_mexicana
ENSMUSG00000040761	Spen	72	75.743	ENSPMEG00000002674	si:ch1073-335m2.2	77	75.743	Poecilia_mexicana
ENSMUSG00000040761	Spen	87	62.222	ENSPREG00000005357	si:ch1073-335m2.2	79	62.222	Poecilia_reticulata
ENSMUSG00000040761	Spen	97	44.284	ENSPREG00000010399	-	91	74.157	Poecilia_reticulata
ENSMUSG00000040761	Spen	100	80.570	ENSPPYG00000001834	SPEN	100	79.805	Pongo_abelii
ENSMUSG00000040761	Spen	88	90.036	ENSPCAG00000009543	SPEN	92	86.544	Procavia_capensis
ENSMUSG00000040761	Spen	100	79.003	ENSPCOG00000021735	SPEN	100	78.223	Propithecus_coquereli
ENSMUSG00000040761	Spen	82	86.066	ENSPVAG00000013794	SPEN	82	86.149	Pteropus_vampyrus
ENSMUSG00000040761	Spen	97	81.461	ENSPNYG00000012379	-	90	47.716	Pundamilia_nyererei
ENSMUSG00000040761	Spen	73	77.041	ENSPNYG00000009042	si:ch1073-335m2.2	58	77.041	Pundamilia_nyererei
ENSMUSG00000040761	Spen	97	83.616	ENSPNAG00000020795	spen	86	77.820	Pygocentrus_nattereri
ENSMUSG00000040761	Spen	90	61.660	ENSPNAG00000011452	si:ch1073-335m2.2	78	61.660	Pygocentrus_nattereri
ENSMUSG00000040761	Spen	99	90.192	ENSRNOG00000033556	Spen	100	89.942	Rattus_norvegicus
ENSMUSG00000040761	Spen	99	79.836	ENSRBIG00000039654	SPEN	100	79.398	Rhinopithecus_bieti
ENSMUSG00000040761	Spen	99	80.169	ENSRROG00000035686	SPEN	100	79.491	Rhinopithecus_roxellana
ENSMUSG00000040761	Spen	97	83.680	ENSSBOG00000028770	SPEN	99	81.633	Saimiri_boliviensis_boliviensis
ENSMUSG00000040761	Spen	95	84.737	ENSSFOG00015010267	si:ch1073-335m2.2	68	84.737	Scleropages_formosus
ENSMUSG00000040761	Spen	68	65.741	ENSSFOG00015007131	si:ch1073-335m2.2	75	65.741	Scleropages_formosus
ENSMUSG00000040761	Spen	97	82.022	ENSSMAG00000008996	-	81	51.843	Scophthalmus_maximus
ENSMUSG00000040761	Spen	97	82.584	ENSSDUG00000003476	-	91	76.208	Seriola_dumerili
ENSMUSG00000040761	Spen	80	67.292	ENSSDUG00000008416	si:ch1073-335m2.2	77	65.447	Seriola_dumerili
ENSMUSG00000040761	Spen	97	82.584	ENSSLDG00000012950	-	91	76.208	Seriola_lalandi_dorsalis
ENSMUSG00000040761	Spen	86	95.370	ENSSPUG00000001866	-	100	95.370	Sphenodon_punctatus
ENSMUSG00000040761	Spen	97	81.461	ENSSPAG00000006014	-	91	75.281	Stegastes_partitus
ENSMUSG00000040761	Spen	80	65.753	ENSSPAG00000012454	si:ch1073-335m2.2	79	58.763	Stegastes_partitus
ENSMUSG00000040761	Spen	85	79.439	ENSSSCG00000034484	SPEN	99	79.088	Sus_scrofa
ENSMUSG00000040761	Spen	78	82.456	ENSTRUG00000021008	si:ch1073-335m2.2	70	82.456	Takifugu_rubripes
ENSMUSG00000040761	Spen	98	43.139	ENSTRUG00000024350	-	74	53.950	Takifugu_rubripes
ENSMUSG00000040761	Spen	90	82.456	ENSTNIG00000014666	si:ch1073-335m2.2	76	82.456	Tetraodon_nigroviridis
ENSMUSG00000040761	Spen	94	74.578	ENSTNIG00000010907	-	55	75.904	Tetraodon_nigroviridis
ENSMUSG00000040761	Spen	77	92.991	ENSTBEG00000003628	SPEN	77	92.991	Tupaia_belangeri
ENSMUSG00000040761	Spen	79	94.419	ENSTTRG00000015704	SPEN	79	94.419	Tursiops_truncatus
ENSMUSG00000040761	Spen	100	79.519	ENSUAMG00000009600	SPEN	100	79.162	Ursus_americanus
ENSMUSG00000040761	Spen	100	78.237	ENSUMAG00000021641	SPEN	100	77.745	Ursus_maritimus
ENSMUSG00000040761	Spen	95	97.778	ENSVVUG00000028951	SPEN	99	100.000	Vulpes_vulpes
ENSMUSG00000040761	Spen	97	56.652	ENSXETG00000023114	SPEN	99	56.911	Xenopus_tropicalis
ENSMUSG00000040761	Spen	72	61.029	ENSXCOG00000004516	si:ch1073-335m2.2	79	61.029	Xiphophorus_couchianus
ENSMUSG00000040761	Spen	97	44.394	ENSXMAG00000021384	-	90	72.453	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	-	ISO	Process
GO:0001085	RNA polymerase II transcription factor binding	-	ISO	Function
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0003677	DNA binding	15778499.	IDA	Function
GO:0003697	single-stranded DNA binding	10451362.	IDA	Function
GO:0003700	DNA-binding transcription factor activity	10451362.	IDA	Function
GO:0003714	transcription corepressor activity	15778499.	IDA	Function
GO:0003714	transcription corepressor activity	-	ISO	Function
GO:0003723	RNA binding	-	IEA	Function
GO:0005515	protein binding	10451362.15778499.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	10451362.15778499.	IDA	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0007219	Notch signaling pathway	-	IEA	Process
GO:0017053	transcriptional repressor complex	-	ISO	Component
GO:0045892	negative regulation of transcription, DNA-templated	10451362.15778499.	IDA	Process
GO:0045892	negative regulation of transcription, DNA-templated	-	ISO	Process
GO:0045893	positive regulation of transcription, DNA-templated	10451362.	IDA	Process
GO:0050769	positive regulation of neurogenesis	-	ISO	Process