EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000043099 (Gene tree)
Gene ID: 15248
Gene Symbol: Hic1
Alias: HIC-1
Full Name: hypermethylated in cancer 1
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 4955 bases
Position: chr11:75164565-75169519
Accession: 1338010
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000053483	zf-C2H2	PF00096.26	5.3e-21	1	4
ENSMUSP00000053483	zf-C2H2	PF00096.26	5.3e-21	2	4
ENSMUSP00000053483	zf-C2H2	PF00096.26	5.3e-21	3	4
ENSMUSP00000053483	zf-C2H2	PF00096.26	5.3e-21	4	4
ENSMUSP00000053483	zf-met	PF12874.7	1.2e-08	1	2
ENSMUSP00000053483	zf-met	PF12874.7	1.2e-08	2	2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000055619	-	3497	XM_017314294	ENSMUSP00000053483	893 (aa)	XP_017169783	Z4YJP0
ENSMUST00000131720	-	645	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000043099's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000043099's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000043099	Hic1	81	95.423	ENSG00000177374	HIC1	100	100.000	Homo_sapiens
ENSMUSG00000043099	Hic1	80	48.604	ENSAPOG00000020900	hic1	85	53.257	Acanthochromis_polyacanthus
ENSMUSG00000043099	Hic1	71	92.476	ENSAMEG00000007657	HIC1	97	90.998	Ailuropoda_melanoleuca
ENSMUSG00000043099	Hic1	80	48.315	ENSAOCG00000023291	hic1	84	53.257	Amphiprion_ocellaris
ENSMUSG00000043099	Hic1	80	49.932	ENSAPEG00000008510	hic1	86	59.701	Amphiprion_percula
ENSMUSG00000043099	Hic1	81	90.509	ENSANAG00000037442	HIC1	98	91.148	Aotus_nancymaae
ENSMUSG00000043099	Hic1	80	49.565	ENSAMXG00000024869	hic1	97	48.280	Astyanax_mexicanus
ENSMUSG00000043099	Hic1	97	90.207	ENSBTAG00000025130	HIC1	98	95.562	Bos_taurus
ENSMUSG00000043099	Hic1	81	94.183	ENSCJAG00000042739	HIC1	98	94.183	Callithrix_jacchus
ENSMUSG00000043099	Hic1	81	95.146	ENSCAFG00000019257	HIC1	98	95.146	Canis_familiaris
ENSMUSG00000043099	Hic1	80	95.098	ENSCAFG00020009802	HIC1	100	95.098	Canis_lupus_dingo
ENSMUSG00000043099	Hic1	81	95.839	ENSCHIG00000015829	HIC1	98	95.839	Capra_hircus
ENSMUSG00000043099	Hic1	56	96.970	ENSTSYG00000032991	HIC1	97	98.958	Carlito_syrichta
ENSMUSG00000043099	Hic1	96	88.413	ENSCPOG00000020382	HIC1	98	93.620	Cavia_porcellus
ENSMUSG00000043099	Hic1	81	93.620	ENSCCAG00000030944	HIC1	98	93.620	Cebus_capucinus
ENSMUSG00000043099	Hic1	81	95.007	ENSCATG00000037347	HIC1	98	95.007	Cercocebus_atys
ENSMUSG00000043099	Hic1	81	95.146	ENSCLAG00000008072	HIC1	98	94.175	Chinchilla_lanigera
ENSMUSG00000043099	Hic1	81	95.146	ENSCSAG00000013805	HIC1	98	95.146	Chlorocebus_sabaeus
ENSMUSG00000043099	Hic1	74	60.448	ENSCPBG00000000255	HIC1	98	59.314	Chrysemys_picta_bellii
ENSMUSG00000043099	Hic1	89	95.990	ENSCGRG00001018912	Hic1	98	98.058	Cricetulus_griseus_chok1gshd
ENSMUSG00000043099	Hic1	92	89.927	ENSCGRG00000008158	Hic1	98	92.510	Cricetulus_griseus_crigri
ENSMUSG00000043099	Hic1	80	48.055	ENSCSEG00000013032	hic1	81	52.896	Cynoglossus_semilaevis
ENSMUSG00000043099	Hic1	83	94.038	ENSDNOG00000049226	HIC1	95	94.038	Dasypus_novemcinctus
ENSMUSG00000043099	Hic1	73	98.347	ENSDORG00000027749	Hic1	77	98.347	Dipodomys_ordii
ENSMUSG00000043099	Hic1	80	95.238	ENSEASG00005009326	HIC1	100	94.678	Equus_asinus_asinus
ENSMUSG00000043099	Hic1	81	95.007	ENSECAG00000030580	HIC1	98	94.452	Equus_caballus
ENSMUSG00000043099	Hic1	80	48.148	ENSELUG00000001329	hic1	52	51.152	Esox_lucius
ENSMUSG00000043099	Hic1	81	95.700	ENSFCAG00000025756	HIC1	98	95.700	Felis_catus
ENSMUSG00000043099	Hic1	79	60.840	ENSFALG00000006543	HIC1	99	58.832	Ficedula_albicollis
ENSMUSG00000043099	Hic1	72	91.989	ENSFDAG00000021489	HIC1	97	94.479	Fukomys_damarensis
ENSMUSG00000043099	Hic1	80	62.756	ENSGALG00000042077	HIC1	96	61.119	Gallus_gallus
ENSMUSG00000043099	Hic1	67	50.760	ENSGACG00000010848	hic1	82	55.973	Gasterosteus_aculeatus
ENSMUSG00000043099	Hic1	81	60.027	ENSGAGG00000025616	HIC1	98	58.177	Gopherus_agassizii
ENSMUSG00000043099	Hic1	71	98.118	ENSGGOG00000027584	HIC1	99	98.118	Gorilla_gorilla
ENSMUSG00000043099	Hic1	94	90.822	ENSHGLG00000012044	HIC1	98	93.759	Heterocephalus_glaber_female
ENSMUSG00000043099	Hic1	71	95.455	ENSHGLG00100013587	HIC1	100	95.455	Heterocephalus_glaber_male
ENSMUSG00000043099	Hic1	80	48.869	ENSHCOG00000001420	hic1	97	46.962	Hippocampus_comes
ENSMUSG00000043099	Hic1	80	49.937	ENSIPUG00000004604	hic1	97	49.296	Ictalurus_punctatus
ENSMUSG00000043099	Hic1	81	95.442	ENSSTOG00000011792	HIC1	98	95.442	Ictidomys_tridecemlineatus
ENSMUSG00000043099	Hic1	81	96.533	ENSJJAG00000017367	Hic1	98	96.533	Jaculus_jaculus
ENSMUSG00000043099	Hic1	80	56.140	ENSLACG00000007028	HIC1	97	55.177	Latimeria_chalumnae
ENSMUSG00000043099	Hic1	64	62.363	ENSLOCG00000006478	hic1	89	61.690	Lepisosteus_oculatus
ENSMUSG00000043099	Hic1	81	87.983	ENSLAFG00000001259	HIC1	100	86.126	Loxodonta_africana
ENSMUSG00000043099	Hic1	81	95.146	ENSMFAG00000044684	HIC1	98	95.146	Macaca_fascicularis
ENSMUSG00000043099	Hic1	80	95.098	ENSMMUG00000048710	HIC1	100	95.098	Macaca_mulatta
ENSMUSG00000043099	Hic1	81	95.146	ENSMNEG00000013172	HIC1	98	95.146	Macaca_nemestrina
ENSMUSG00000043099	Hic1	80	49.375	ENSMAMG00000017930	hic1	84	52.874	Mastacembelus_armatus
ENSMUSG00000043099	Hic1	60	71.921	ENSMGAG00000005397	HIC1	93	71.429	Meleagris_gallopavo
ENSMUSG00000043099	Hic1	81	98.336	ENSMAUG00000019881	Hic1	98	98.336	Mesocricetus_auratus
ENSMUSG00000043099	Hic1	81	95.007	ENSMICG00000012908	HIC1	98	95.007	Microcebus_murinus
ENSMUSG00000043099	Hic1	81	94.730	ENSMOCG00000001275	Hic1	98	94.730	Microtus_ochrogaster
ENSMUSG00000043099	Hic1	81	49.015	ENSMMOG00000014282	hic1	52	50.569	Mola_mola
ENSMUSG00000043099	Hic1	81	62.331	ENSMODG00000010600	HIC1	98	71.274	Monodelphis_domestica
ENSMUSG00000043099	Hic1	100	94.396	MGP_CAROLIEiJ_G0016730	-	100	94.396	Mus_caroli
ENSMUSG00000043099	Hic1	100	99.216	MGP_SPRETEiJ_G0017573	Hic1	100	99.300	Mus_spretus
ENSMUSG00000043099	Hic1	80	94.958	ENSMPUG00000019502	HIC1	100	94.958	Mustela_putorius_furo
ENSMUSG00000043099	Hic1	72	93.878	ENSMLUG00000010527	HIC1	98	93.878	Myotis_lucifugus
ENSMUSG00000043099	Hic1	81	96.810	ENSNGAG00000020689	Hic1	98	96.810	Nannospalax_galili
ENSMUSG00000043099	Hic1	56	95.200	ENSNLEG00000035047	-	81	95.200	Nomascus_leucogenys
ENSMUSG00000043099	Hic1	81	94.444	ENSODEG00000007964	HIC1	99	93.889	Octodon_degus
ENSMUSG00000043099	Hic1	80	47.453	ENSORLG00000029930	hic1	51	51.408	Oryzias_latipes
ENSMUSG00000043099	Hic1	80	46.780	ENSORLG00020008812	hic1	84	52.918	Oryzias_latipes_hni
ENSMUSG00000043099	Hic1	80	46.902	ENSORLG00015000406	hic1	84	53.488	Oryzias_latipes_hsok
ENSMUSG00000043099	Hic1	80	47.821	ENSOMEG00000004793	hic1	84	52.918	Oryzias_melastigma
ENSMUSG00000043099	Hic1	81	94.868	ENSOGAG00000034845	HIC1	98	94.868	Otolemur_garnettii
ENSMUSG00000043099	Hic1	81	95.700	ENSPPRG00000013038	HIC1	98	95.700	Panthera_pardus
ENSMUSG00000043099	Hic1	81	95.423	ENSPTRG00000047506	HIC1	98	95.423	Pan_troglodytes
ENSMUSG00000043099	Hic1	70	87.460	ENSPANG00000024595	HIC1	95	88.468	Papio_anubis
ENSMUSG00000043099	Hic1	64	62.447	ENSPKIG00000013932	hic1	73	62.069	Paramormyrops_kingsleyae
ENSMUSG00000043099	Hic1	62	57.539	ENSPSIG00000007902	HIC1	99	56.000	Pelodiscus_sinensis
ENSMUSG00000043099	Hic1	80	49.393	ENSPMGG00000011581	hic1	98	47.354	Periophthalmus_magnuspinnatus
ENSMUSG00000043099	Hic1	81	98.613	ENSPEMG00000021229	Hic1	98	98.613	Peromyscus_maniculatus_bairdii
ENSMUSG00000043099	Hic1	81	77.793	ENSPCIG00000019061	HIC1	98	78.638	Phascolarctos_cinereus
ENSMUSG00000043099	Hic1	80	48.367	ENSPFOG00000004471	hic1	51	50.115	Poecilia_formosa
ENSMUSG00000043099	Hic1	80	48.866	ENSPLAG00000022329	hic1	51	50.577	Poecilia_latipinna
ENSMUSG00000043099	Hic1	80	48.676	ENSPMEG00000004584	hic1	51	50.115	Poecilia_mexicana
ENSMUSG00000043099	Hic1	80	48.485	ENSPREG00000010341	hic1	84	54.688	Poecilia_reticulata
ENSMUSG00000043099	Hic1	70	97.959	ENSPPYG00000007789	HIC1	97	97.959	Pongo_abelii
ENSMUSG00000043099	Hic1	57	96.610	ENSPCAG00000000535	HIC1	70	96.610	Procavia_capensis
ENSMUSG00000043099	Hic1	81	94.730	ENSPCOG00000023965	HIC1	98	94.730	Propithecus_coquereli
ENSMUSG00000043099	Hic1	81	95.146	ENSPVAG00000002158	HIC1	98	95.146	Pteropus_vampyrus
ENSMUSG00000043099	Hic1	81	54.107	ENSPNAG00000001133	hic1	98	50.988	Pygocentrus_nattereri
ENSMUSG00000043099	Hic1	60	99.064	ENSRNOG00000046405	Hic1	99	99.064	Rattus_norvegicus
ENSMUSG00000043099	Hic1	81	95.604	ENSRNOG00000057619	LOC100912068	98	95.467	Rattus_norvegicus
ENSMUSG00000043099	Hic1	81	95.146	ENSRROG00000031780	HIC1	98	95.146	Rhinopithecus_roxellana
ENSMUSG00000043099	Hic1	80	47.229	ENSSFOG00015005452	hic1	82	54.864	Scleropages_formosus
ENSMUSG00000043099	Hic1	77	49.012	ENSSFOG00015004559	hic1	94	38.592	Scleropages_formosus
ENSMUSG00000043099	Hic1	80	49.125	ENSSMAG00000009823	hic1	83	55.769	Scophthalmus_maximus
ENSMUSG00000043099	Hic1	80	48.875	ENSSLDG00000002022	hic1	84	53.640	Seriola_lalandi_dorsalis
ENSMUSG00000043099	Hic1	81	59.010	ENSSPUG00000007168	HIC1	97	56.361	Sphenodon_punctatus
ENSMUSG00000043099	Hic1	81	94.183	ENSSSCG00000025717	HIC1	98	94.044	Sus_scrofa
ENSMUSG00000043099	Hic1	80	63.215	ENSTGUG00000005835	HIC1	99	61.757	Taeniopygia_guttata
ENSMUSG00000043099	Hic1	80	95.518	ENSUAMG00000025149	HIC1	100	95.518	Ursus_americanus
ENSMUSG00000043099	Hic1	80	95.098	ENSVVUG00000021725	HIC1	100	95.098	Vulpes_vulpes
ENSMUSG00000043099	Hic1	80	60.573	ENSXETG00000023803	hic1	99	58.799	Xenopus_tropicalis
ENSMUSG00000043099	Hic1	80	48.496	ENSXCOG00000009641	hic1	53	50.000	Xiphophorus_couchianus
ENSMUSG00000043099	Hic1	80	47.990	ENSXMAG00000023343	hic1	84	55.078	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	16269335.	IDA	Process
GO:0000122	negative regulation of transcription by RNA polymerase II	-	ISO	Process
GO:0000785	chromatin	16269335.	IDA	Component
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	-	ISO	Function
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003700	DNA-binding transcription factor activity	-	ISO	Function
GO:0005515	protein binding	16269335.16724116.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005829	cytosol	-	ISO	Component
GO:0006974	cellular response to DNA damage stimulus	21873635.	IBA	Process
GO:0007275	multicellular organism development	-	IEA	Process
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	16269335.	IDA	Process
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	-	ISO	Process
GO:0016055	Wnt signaling pathway	-	IEA	Process
GO:0030178	negative regulation of Wnt signaling pathway	-	ISO	Process
GO:0042826	histone deacetylase binding	-	ISO	Function
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	16269335.	IMP	Process
GO:0043565	sequence-specific DNA binding	-	ISO	Function
GO:0046872	metal ion binding	-	IEA	Function